Tetrafluorophenolate of HBED-CC: A versatile conjugation agent for 68Ga-labeled small recombinant antibodies

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 35, Issue 10, 2008, Pages 1878-1886

  Eder, Matthias ^a   Wängler, Björn ^a   Knackmuss, Stefan ^b   LeGall, Fabrice ^b   Little, Melvyn ^b   Haberkorn, Uwe ^c   Mier, Walter ^c   Eisenhut, Michael ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b Affimed GmbH   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

68Ga; Conjugation chemistry; Diabody; HBED CC; Recombinant antibodies

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; 2,3,5,6 TETRAFLUOROPHENOLATE; 4 (2 HYDROXYETHYL) 1 PIPERAZINEETHANESULFONIC ACID; EDETIC ACID DERIVATIVE; EPIDERMAL GROWTH FACTOR RECEPTOR; GALLIUM 68; IMMUNOGLOBULIN ANTIBODY; MONOCLONAL ANTIBODY; N,N' BIS[2 HYDROXY 5 (CARBOXYETHYL)BENZYL]ETHYLENEDIAMINE N,N' DIACETIC ACID MONOCLONAL ANTIBODY 425 GA 68; N,N' BIS[2 HYDROXY 5 (CARBOXYETHYL)BENZYL]ETHYLENEDIAMINE N,N' DIACETIC ACID TETRAFLUOROPHENOL ESTER; PHENOL DERIVATIVE; RECOMBINANT ANTIBODY; RECOMBINANT DIABODY; RECOMBINANT PROTEIN; TETRAFLUOROPHENOLATE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HT29; COMPLEX FORMATION; CONTROLLED STUDY; DRUG CLEARANCE; DRUG CONJUGATION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IMMUNOGLOBULIN VARIABLE REGION; ISOTOPE LABELING; MOLECULAR IMAGING; NEUROENDOCRINE TUMOR; POSITRON EMISSION TOMOGRAPHY;

ANTIBODIES; EDETIC ACID; GALLIUM RADIOISOTOPES; HETEROCYCLIC COMPOUNDS, 1-RING; ISOTOPE LABELING; PEPTIDES; RADIOPHARMACEUTICALS; RECOMBINANT PROTEINS;

EID: 52449110518     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-008-0816-z     Document Type: Article

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