Radiometal-labelled macrocyclic chelator-derivatised somatostatin analogue with superb tumour-targeting properties and potential for receptor-mediated internal radiotherapy

Chemistry - A European Journal

Volumn 5, Issue 7, 1999, Pages 1974-1981

  Heppeler, A ^a   Froidevaux, S ^a   Macke H R ^a   Jermann, E ^a   Behe M ^a   Powell, P ^a   Hennig, M ^b  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Gallium; Macrocyclic ligands; Peptides; Radiopharmaceuticals; Yttrium

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; 4,7,10 TRICARBOXYMETHYL TERT BUTYL ESTER 1,4,7,10 TETRAAZACYCLODODECANE 1 ACETIC ACID; CHELATING AGENT; GADOTERIC ACID; OCTREOTIDE; SOMATOSTATIN ANALOG; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CANCER RADIOTHERAPY; CHELATION; CRYSTAL STRUCTURE; DRUG RECEPTOR BINDING; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; ISOTOPE LABELING; MOUSE; NONHUMAN; SOLID PHASE EXTRACTION; STRUCTURE ANALYSIS; TARGET CELL DESTRUCTION; TUMOR CELL DESTRUCTION;

EID: 0033033382     PISSN: 09476539     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1521-3765(19990702)5:7<1974::aid-chem1974>3.0.co;2-x     Document Type: Article

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