-
1
-
-
0027303686
-
Highly specific in vivo tumor targeting by monovalent and divalent forms of 741f8 anti-c-erbb-2 single-chain fv
-
Adams, G.P., McCartney, J.E., Tai, M.-S., Oppermann, H., Huston, J.S., Stafford, W.F., Bookman, M.A., Fand, I., Houston, L.L. and Weiner, L.M. (1993) Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 anti-c-erbB-2 single-chain Fv. Cancer Res. 53, 4026.
-
(1993)
Cancer Res.
, vol.53
, pp. 4026
-
-
Adams, G.P.1
McCartney, J.E.2
Tai, M.-S.3
Oppermann, H.4
Huston, J.S.5
Stafford, W.F.6
Bookman, M.A.7
Fand, I.8
Houston, L.L.9
Weiner, L.M.10
-
2
-
-
0024293979
-
Single-chain antigen-binding proteins
-
Bird, R.E., Hardman, K.D., Jacobson, J.W., Johnson, S., Kaufman, B.M., Lee, S.-M., Lee, T., Pope, S.H., Riordan, G.S. and Whitlow, M. (1988) Single-chain antigen-binding proteins. Science 242, 423.
-
(1988)
Science
, vol.242
, pp. 423
-
-
Bird, R.E.1
Hardman, K.D.2
Jacobson, J.W.3
Johnson, S.4
Kaufman, B.M.5
Lee, S.-M.6
Lee, T.7
Pope, S.H.8
Riordan, G.S.9
Whitlow, M.10
-
3
-
-
0025123399
-
Folding and aggregation of β-lactamase in the periplasmic space of escherichia coli
-
Bowden, G.A. and Georgiou, G. (1990) Folding and aggregation of β-lactamase in the periplasmic space of Escherichia coli. J. Biol. Chem. 265, 16760.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 16760
-
-
Bowden, G.A.1
Georgiou, G.2
-
4
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248
-
-
Bradford, M.M.1
-
5
-
-
0025944567
-
A surface expression vector for antibody screening
-
Breitling, F., Dübel, S., Seehaus, T., Klewinghaus, I. and Little, M. (1991) A surface expression vector for antibody screening. Gene 104, 147.
-
(1991)
Gene
, vol.104
, pp. 147
-
-
Breitling, F.1
Dübel, S.2
Seehaus, T.3
Klewinghaus, I.4
Little, M.5
-
6
-
-
0006454079
-
Renaturation, purification and characterization of recombinant fab-fragments produced in escherichia coli
-
Buchner, J. and Rudolph, R. (1991) Renaturation, purification and characterization of recombinant Fab-fragments produced in Escherichia coli. Bio/Technology 9, 157.
-
(1991)
Bio/technology
, vol.9
, pp. 157
-
-
Buchner, J.1
Rudolph, R.2
-
7
-
-
0026792807
-
A method for increasing the yield of properly folded recombinant fusion proteins: Single-chain immunotoxins from renaturation of bacterial inclusion bodies
-
Buchner, J., Pastan, I. and Brinkmann, U. (1992) A method for increasing the yield of properly folded recombinant fusion proteins: single-chain immunotoxins from renaturation of bacterial inclusion bodies. Anal. Biochem. 205, 263.
-
(1992)
Anal. Biochem.
, vol.205
, pp. 263
-
-
Buchner, J.1
Pastan, I.2
Brinkmann, U.3
-
8
-
-
0027975979
-
Intra- and extracellular expression of an scfv antibody fragment in e. Coli: Effect of bacterial strains and pathway engineering using groes/l chaperonins
-
Duenas, M., Vazquez, J., Ayala, M., Söderlind, E., Ohlin, M., Perez, L., Borrebaeck, C.A.K. and Gavilondo, J.V. (1994) Intra- and extracellular expression of an scFv antibody fragment in E. coli: effect of bacterial strains and pathway engineering using GroES/L chaperonins. BioTechniques 16, 476.
-
(1994)
Biotechniques
, vol.16
, pp. 476
-
-
Duenas, M.1
Vazquez, J.2
Ayala, M.3
Söderlind, E.4
Ohlin, M.5
Perez, L.6
Borrebaeck, C.A.K.7
Gavilondo, J.V.8
-
9
-
-
0028316085
-
Redirection of t-cell mediated cytotoxicity by a recombinant single-chain fv molecule
-
George, A.J.T., Titus, J.A., Jost, C.R., Kurucz, I., Perez, P., Andrew, S.M., Nicholls, P.J., Huston, J.S. and Segal, D.M. (1994) Redirection of T-cell mediated cytotoxicity by a recombinant single-chain Fv molecule. J. Immunol. 152, 1802.
-
(1994)
J. Immunol.
, vol.152
, pp. 1802
-
-
George, A.J.T.1
Titus, J.A.2
Jost, C.R.3
Kurucz, I.4
Perez, P.5
Andrew, S.M.6
Nicholls, P.J.7
Huston, J.S.8
Segal, D.M.9
-
10
-
-
0024448151
-
Calculation of protein extinction coefficients from amino acid sequence data
-
Gill, S.C. and von Hippel, P.H. (1989) Calculation of protein extinction coefficients from amino acid sequence data. Anal. Biochem. 182, 319.
-
(1989)
Anal. Biochem.
, vol.182
, pp. 319
-
-
Gill, S.C.1
Von Hippel, P.H.2
-
11
-
-
0025162270
-
A comparison of strategies to stabilize immunoglobulin fv-fragments
-
Glockshuber, R., Malia, M., Pfitzinger, I. and Plückthun, A. (1990) A comparison of strategies to stabilize immunoglobulin Fv-fragments. Biochemistry 29, 1362.
-
(1990)
Biochemistry
, vol.29
, pp. 1362
-
-
Glockshuber, R.1
Malia, M.2
Pfitzinger, I.3
Plückthun, A.4
-
12
-
-
0004198722
-
Protein engineering of antibody binding sites: Recovery of specific activity in an anti-digoxin single-chain fv analogue produced in escherichia coli
-
Huston, J.S., Levinson, D., Mudgett-Hunter, M., Tai, M.-S., Novotny, J.M., Margolies, N., Ridge, R.J., Bruccolery, R.E., Haber, E., Crea, R. and Oppermann, H. (1988) Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli. Proc. Natl. Acad. Sci. USA 85, 5879.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 5879
-
-
Huston, J.S.1
Levinson, D.2
Mudgett-Hunter, M.3
Tai, M.-S.4
Novotny, J.M.5
Margolies, N.6
Ridge, R.J.7
Bruccolery, R.E.8
Haber, E.9
Crea, R.10
Oppermann, H.11
-
13
-
-
0026334521
-
Protein engineering of single-chain fv analogs and fusion proteins
-
Huston, J.S., Mudgett-Hunter, M., Tai, M.-S., McCartney, J., Warren, F., Haber, E. and Oppermann, H. (1991) Protein engineering of single-chain Fv analogs and fusion proteins. Methods Enzymol. 203, 46.
-
(1991)
Methods Enzymol.
, vol.203
, pp. 46
-
-
Huston, J.S.1
Mudgett-Hunter, M.2
Tai, M.-S.3
McCartney, J.4
Warren, F.5
Haber, E.6
Oppermann, H.7
-
14
-
-
14744271625
-
Protein aggregation in vitro and in vivo: A quantitative model of the kinetic competition between folding and aggregation
-
Kiefhaber, T., Rudolf, R., Kohler, H.-H. and Buchner, J. (1991) Protein aggregation in vitro and in vivo: a quantitative model of the kinetic competition between folding and aggregation. Bio/Technology 9, 825.
-
(1991)
Bio/technology
, vol.9
, pp. 825
-
-
Kiefhaber, T.1
Rudolf, R.2
Kohler, H.-H.3
Buchner, J.4
-
15
-
-
0028001154
-
Recombinant single-chain fv fragments carrying c-terminal cysteine residues: Production of bivalent and biotinylated miniantibodies
-
Kipriyanov, S.M., Dübel, S., Breitling, F., Kontermann, R.E. and Little, M. (1994) Recombinant single-chain Fv fragments carrying C-terminal cysteine residues: production of bivalent and biotinylated miniantibodies. Mol. Immunol. 31, 1047.
-
(1994)
Mol. Immunol.
, vol.31
, pp. 1047
-
-
Kipriyanov, S.M.1
Dübel, S.2
Breitling, F.3
Kontermann, R.E.4
Little, M.5
-
16
-
-
0029877588
-
Affinity enhancement of a recombinant antibody: Formation of complexes with multiple valency by a single-chain fv fragment-core streptavidin fusion
-
Kipriyanov, S.M., Little, M., Kropshofer, H., Breitling, F., Gotter, S. and Dübel, S. (1996a) Affinity enhancement of a recombinant antibody: formation of complexes with multiple valency by a single-chain Fv fragment-core streptavidin fusion. Protein Eng. 9, 203.
-
(1996)
Protein Eng.
, vol.9
, pp. 203
-
-
Kipriyanov, S.M.1
Little, M.2
Kropshofer, H.3
Breitling, F.4
Gotter, S.5
Dübel, S.6
-
17
-
-
0029793209
-
Rapid detection of recombinant antibody fragments directed against cell-surface antigens by flow cytometry
-
Kipriyanov, S.M., Kupriyanova, O.A., Little, M. and Moldenhauer, G. (1996b) Rapid detection of recombinant antibody fragments directed against cell-surface antigens by flow cytometry. J. Immunol. Methods 196, 51.
-
(1996)
J. Immunol. Methods
, vol.196
, pp. 51
-
-
Kipriyanov, S.M.1
Kupriyanova, O.A.2
Little, M.3
Moldenhauer, G.4
-
18
-
-
0027526906
-
The effect of folding catalysts on the in vivo folding process of different antibody fragments expressed in escherichia coli
-
Knappik, A., Krebber, C. and Plückthun, A. (1993) The effect of folding catalysts on the in vivo folding process of different antibody fragments expressed in Escherichia coli. Bio/Technology 11, 77.
-
(1993)
Bio/technology
, vol.11
, pp. 77
-
-
Knappik, A.1
Krebber, C.2
Plückthun, A.3
-
19
-
-
0028966985
-
Engineered turns of a recombinant antibody improve its in vivo folding
-
Knappik, A. and Plückthun, A. (1995) Engineered turns of a recombinant antibody improve its in vivo folding. Protein Eng. 8, 81.
-
(1995)
Protein Eng.
, vol.8
, pp. 81
-
-
Knappik, A.1
Plückthun, A.2
-
20
-
-
0023613953
-
Rapid and efficient site-specific mutagenesis without phenotypic selection
-
Kunkel, T.A., Roberts, J.D. and Zakour, R.A. (1987) Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol. 154, 367.
-
(1987)
Methods Enzymol.
, vol.154
, pp. 367
-
-
Kunkel, T.A.1
Roberts, J.D.2
Zakour, R.A.3
-
21
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of the bacteriophage t4
-
Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature 227, 680.
-
(1970)
Nature
, vol.227
, pp. 680
-
-
Laemmli, U.K.1
-
22
-
-
0345077411
-
Promoters largely determine the efficiency of repressor action
-
Lanzer, M. and Bujard, H. (1988) Promoters largely determine the efficiency of repressor action. Proc. Natl. Acad. Sci. USA 85, 8973.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 8973
-
-
Lanzer, M.1
Bujard, H.2
-
23
-
-
0028285385
-
Recombinant single-chain antibody peptide conjugates expressed in escherichia coli for the rapid diagnosis of hiv
-
Lilley, G.G., Dolezal, O., Hillyard, C.J., Bernard, C. and Hudson, P. (1994) Recombinant single-chain antibody peptide conjugates expressed in Escherichia coli for the rapid diagnosis of HIV. J. Immunol. Methods 171, 211.
-
(1994)
J. Immunol. Methods
, vol.171
, pp. 211
-
-
Lilley, G.G.1
Dolezal, O.2
Hillyard, C.J.3
Bernard, C.4
Hudson, P.5
-
24
-
-
0018257739
-
Inheritance of antibody specificity
-
Mäkelä, O., Kaartinen, M., Pelkonen, J.L.T. and Karjalainen, K. (1978) Inheritance of antibody specificity. V. J. Exp. Med. 148, 1644.
-
(1978)
V. J. Exp. Med.
, vol.148
, pp. 1644
-
-
Mäkelä, O.1
Kaartinen, M.2
Pelkonen, J.L.T.3
Karjalainen, K.4
-
25
-
-
14744300211
-
By-passing immunization: Building high affinity human antibodies by chain shuffling
-
Marks, J.D., Griffiths, A.D., Andrew, D., Malmquist, M., Clackson, T., Bye, J. and Winter, G. (1992) By-passing immunization: building high affinity human antibodies by chain shuffling. Bio/Technology 10, 779.
-
(1992)
Bio/technology
, vol.10
, pp. 779
-
-
Marks, J.D.1
Griffiths, A.D.2
Andrew, D.3
Malmquist, M.4
Clackson, T.5
Bye, J.6
Winter, G.7
-
26
-
-
0026327378
-
Construction, binding properties, metabolism, and tumor targeting of a single-chain fv derived from the pancarcinoma monoclonal antibody cc49
-
Milenic, D.E., Yokota, T., Filpula, D.R., Finkelman, M.A.J., Dodd, S.W., Wood, J.F., Whitlow, M., Snoy P. and Schlom, J. (1991) Construction, binding properties, metabolism, and tumor targeting of a single-chain Fv derived from the pancarcinoma monoclonal antibody CC49. Cancer Res. 51, 6363.
-
(1991)
Cancer Res.
, vol.51
, pp. 6363
-
-
Milenic, D.E.1
Yokota, T.2
Filpula, D.R.3
Finkelman, M.A.J.4
Dodd, S.W.5
Wood, J.F.6
Whitlow, M.7
Snoy, P.8
Schlom, J.9
-
27
-
-
0001708437
-
Antibodies from escherichia coli
-
M. Rosenberg and G.P. Moore (Eds.), Springer-Verlag, Berlin
-
Plückthun, A. 1994. Antibodies from Escherichia coli. In: M. Rosenberg and G.P. Moore (Eds.), Handbook of Experimental Pharmacology, Vol. 113, The Pharmacology of Monoclonal Antibodies. Springer-Verlag, Berlin, p. 269
-
(1994)
Handbook of Experimental Pharmacology, Vol. 113, The Pharmacology of Monoclonal Antibodies
, vol.113
, pp. 269
-
-
Plückthun, A.1
-
28
-
-
0027450561
-
The complete general secretory pathway in gram-negative bacteria
-
Pugsley, A.P. (1993) The complete general secretory pathway in gram-negative bacteria. Microbiol. Rev. 57, 50.
-
(1993)
Microbiol. Rev.
, vol.57
, pp. 50
-
-
Pugsley, A.P.1
-
29
-
-
0027361585
-
High-level production of an active single-chain fv fragment in the culture supernatant of escherichia coli
-
C. Terhorst, F. Malavasi, A. Albertini (Eds.), Karger, Basel
-
Sizmann, D., Takkinen, K., Laukkanen, M.-L., Saloheimo, M., Candussio, A., Veijola-Bailey, P. and Teeri, T.T. (1993) High-level production of an active single-chain Fv fragment in the culture supernatant of Escherichia coli. In: C. Terhorst, F. Malavasi, A. Albertini (Eds.), Year Immunol., Vol. 7, Generation of antibodies by cell and gene immortalization. Karger, Basel, p. 119.
-
(1993)
Year Immunol., Vol. 7, Generation of Antibodies by Cell and Gene Immortalization
, vol.7
, pp. 119
-
-
Sizmann, D.1
Takkinen, K.2
Laukkanen, M.-L.3
Saloheimo, M.4
Candussio, A.5
Veijola-Bailey, P.6
Teeri, T.T.7
-
30
-
-
0026350603
-
Secretion and in vivo folding of the fab fragment of the antibody mcpc603 in escherichia coli: Influence of disulfides and cis-prolines
-
Skerra, A. and Plückthim, A. (1991) Secretion and in vivo folding of the Fab fragment of the antibody McPC603 in Escherichia coli: influence of disulfides and cis-prolines. Protein Eng. 4, 971.
-
(1991)
Protein Eng.
, vol.4
, pp. 971
-
-
Skerra, A.1
Plückthim, A.2
-
31
-
-
0027312336
-
Bacterial expression of immunoglobulin fragments
-
Skerra, A. (1993) Bacterial expression of immunoglobulin fragments. Curr. Opin. Immunol. 5, 256.
-
(1993)
Curr. Opin. Immunol.
, vol.5
, pp. 256
-
-
Skerra, A.1
-
32
-
-
0025952336
-
An active single-chain antibody containing a cellulase linker domain is secreted by escherichia coli
-
Takkinen, K., Laukkanen, M.-L., Sizmann, D., Alfthan, K., Immonen, T., Vanne, L., Kaartinen, M., Knowles, J.K.C. and Teeri, T.T. (1991) An active single-chain antibody containing a cellulase linker domain is secreted by Escherichia coli. Protein Eng. 4, 837.
-
(1991)
Protein Eng.
, vol.4
, pp. 837
-
-
Takkinen, K.1
Laukkanen, M.-L.2
Sizmann, D.3
Alfthan, K.4
Immonen, T.5
Vanne, L.6
Kaartinen, M.7
Knowles, J.K.C.8
Teeri, T.T.9
-
33
-
-
0018836897
-
Okt3: A monoclonal anti-human t lymphocyte antibody with potent mytogenic properties
-
Van Wauwe, J.P, DeMey, J.R. and Goossens, J.G. (1980) OKT3: a monoclonal anti-human T lymphocyte antibody with potent mytogenic properties. J. Immunol. 124, 2708.
-
(1980)
J. Immunol.
, vol.124
, pp. 2708
-
-
Van Wauwe, J.P.1
Demey, J.R.2
Goossens, J.G.3
-
34
-
-
0028955645
-
Amino acid sequence based pcr primers for amplification of rearranged human heavy and light chain immunoglobulin variable region genes
-
Welschof, M., Terness, P., Kolbinger, F., Zewe, M., Dübel, S., Dörsam, H., Hain, C., Finger, M., Jung, M., Moldenhauer, G., Hayashi, N., Little, M. and Opelz, G. (1995) Amino acid sequence based PCR primers for amplification of rearranged human heavy and light chain immunoglobulin variable region genes. J. Immunol. Methods 179, 203.
-
(1995)
J. Immunol. Methods
, vol.179
, pp. 203
-
-
Welschof, M.1
Terness, P.2
Kolbinger, F.3
Zewe, M.4
Dübel, S.5
Dörsam, H.6
Hain, C.7
Finger, M.8
Jung, M.9
Moldenhauer, G.10
Hayashi, N.11
Little, M.12
Opelz, G.13
-
36
-
-
0026684815
-
Rapid tumor penetration of a single-chain fv and comparison with other immunoglobulin forms
-
Yokota, T., Milenic, D.E., Whitlow, M. and Schlom, J. (1992) Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms. Cancer Res. 52, 3402.
-
(1992)
Cancer Res.
, vol.52
, pp. 3402
-
-
Yokota, T.1
Milenic, D.E.2
Whitlow, M.3
Schlom, J.4
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