Immune regulation and tolerance to fungi in the lungs and skin

Chemical Immunology and Allergy

Volumn 94, Issue , 2008, Pages 124-137

  Romani, L ^a   Puccetti, P ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

INDOLEAMINE 2,3 DIOXYGENASE; TRYPTOPHAN;

ALLERGIC ASTHMA; ALLERGIC PNEUMONITIS; ALLERGIC RHINITIS; ATOPIC DERMATITIS; BRONCHOPULMONARY ASPERGILLOMA; DENDRITIC CELL; DERMATOMYCOSIS; HUMAN; IMMUNOPATHOGENESIS; IMMUNOREGULATION; INFLAMMATION; INNATE IMMUNITY; LUNG MYCOSIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH2 CELL;

ANIMALS; ANTIBODIES, FUNGAL; ANTIGENS, FUNGAL; DERMATOMYCOSES; FEEDBACK, BIOCHEMICAL; FUNGI; HOMEOSTASIS; HUMANS; IMMUNE TOLERANCE; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; LUNG DISEASES, FUNGAL; MOLECULAR MIMICRY; RESPIRATORY HYPERSENSITIVITY; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY;

EID: 52249110428     PISSN: 16602242     EISSN: None     Source Type: Book Series    
DOI: 10.1159/000154957     Document Type: Review

References (62)

1. Crameri R, Weichel M, Fluckiger S, Glaser AG, Rhyner C: Fungal allergies: a yet unsolved problem. Chem Immunol Allergy 2006;91:121-133.
2. Simon-Nobbe B, Denk U, Poll V, Rid R, Breitenbach M: The spectrum of fungal allergy. Int Arch Allergy Immunol 2007;145:58-86.
3. Denning DW, O'Driscoll BR, Hogaboam CM, Bowyer P, Niven RM: The link between fungi and severe asthma: a summary of the evidence. Eur Respir J 2006;27:615-626.
4. Virnig C, Bush RK: Allergic bronchopulmonary aspergillosis: a US perspective. Curr Opin Pulm Med 2007;13:67-71.
5. Zeller S, Glaser AG, Vilhelmsson M, Rhyner C, Crameri R: Immunoglobulin-E-mediated reactivity to self antigens: a controversial issue. Int Arch Allergy Immunol 2007;145:87-93.
6. Ashbee HR: Recent developments in the immunology and biology of Malassezia species. FEMS Immunol Med Microbiol 2006;47:14-23.
7. Lilic D: New perspectives on the immunology of chronic mucocutaneous candidiasis. Curr Opin Infect Dis 2002;15:143-147.
8. Romani L, Puccetti P: Protective tolerance to fungi: the role of IL-10 and tryptophan catabolism. Trends Microbiol 2006;14:183-189.
9. Brown, GD: Dectin-1: a signalling non-TLR pattern-recognition receptor. Nat Rev Immunol 2006;6:33-43.
10. McGirt LY, Beck LA: Innate immune defects in atopic dermatitis. J Allergy Clin Immunol 2006;118:202-208.
11. Baker BS: The role of microorganisms in atopic dermatitis. Clin Exp Immunol 2006;144:1-9.
12. Montagnoli C, Bozza S, Gaziano R, Zelante T, Bonifazi P, Moretti S, Bellocchio S, Pitzurra L, Romani L: Immunity and tolerance to Aspergillus fumigatus. Novartis Found Symp 2006;279:66-77.
13. Romani L, Bistoni F, Puccetti P: Fungi, dendritic cells and receptors: a host perspective of fungal virulence. Trends Microbiol 2002;10:508-514.
14. Buentke E, D'Amato M, Scheynius A: Malassezia enhances natural killer cell-induced dendritic cell maturation. Scand J Immunol 2004;59:511-516.
15. Buentke E, Scheynius A: Dendritic cells and fungi. APMIS 2003;111:789-796.
16. Guttman-Yassky E, Lowes MA, Fuentes-Duculan J, Whynot J, Novitskaya I, Cardinale I, Haider A, Khatcherian A, Carucci JA, Bergman R, Krueger JG: Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis. J Allergy Clin Immunol 2007;119:1210-1217.
17. Colonna M, Trinchieri G, Liu YJ: Plasma cytoid dendritic cells in immunity. Nat Immunol 2004;5:1219-1226.
18. Grohmann U, Fallarino F, Puccetti P: Tolerance, DCs and tryptophan: much ado about IDO. Trends Immunol 2003;24:242-248.
19. Mellor AL, Munn DH: IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol 2004;4:762-774.
20. Romani L: Immunity to fungal infections. Nat Rev Immunol 2004;4:1-23.
21. Lilic D, Gravenor I, Robson N, Lammas DA, Drysdale P, Calvert JE, Cant AJ, Abinun M: Deregulated production of protective cytokines in response to Candida albicans infection in patients with chronic mucocutaneous candidiasis. Infect Immun 2003;71:5690-5699.
22. Sambatakou H, Pravica V, Hutchinson IV, Denning DW: Cytokine profiling of pulmonary aspergillosis. Int J Immunogenet 2006;33:297-302.
23. Woodfolk JA: Allergy and dermatophytes. Clin Microbiol Rev 2005;18:30-43.
24. Rieg S, Steffen H, Seeber S, Humeny A, Kalbacher H, Dietz K, Garbe C, Schittek B: Deficiency of dermcidin-derived antimicrobial peptides in sweat of patients with atopic dermatitis correlates with an impaired innate defense of human skin in vivo. J Immunol 2005;174:8003-8010.
25. Burton OT, Zaccone P: The potential role of chitin in allergic reactions. Trends Immunol 2007.
26. Zhu Z, Zheng T, Homer RJ, Kim YK, Chen NY, Cohn L, Hamid Q, Elias JA: Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation. Science 2004;304:1678-1682.
27. Bullens DM: Measuring T-cell cytokines in allergic upper and lower airway inflammation: can we move to the clinic? Inflamm Allergy Drug Targets 2007;6:81-90.
28. Zheng Y, Danilenko DM, Valdez P, Kasman I, Eastham-Anderson J, Wu J, Ouyang W: Interleukin-22, a Th17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature 2007;445:648-651.
29. Crameri R, Faith A, Hemmann S, Jaussi R, Ismail C, Menz G, Blaser K: Humoral and cell-mediated autoimmunity in allergy to Aspergillus fumigatus. J Exp Med 1996;18:265-270.
30. Mayer C, Appenzeller U, Seelbach H, Achatz G, Oberkofler H, Breitenbach M, Blaser K, Crameri R: Humoral and cell-mediated autoimmune reactions to human acidic ribosomal P2 protein in individuals sensitized to Aspergillus fumigatus P2 protein. J Exp Med 1999;189:1507-1512.
31. Schmid-Grendelmeier P, Fluckiger S, Disch R, Trautmann A, Wuthrich B, Blaser K, Scheynius A, Crameri R: IgE-mediated and T cell-mediated autoimmunity against manganese superoxide dismutase in atopic dermatitis. J Allergy Clin Immunol 2005;115:1068-1075.
32. Singh N, Perfect JR: Immune reconstitution syndrome associated with opportunistic mycoses. Lancet Infect Dis 2007;7:395-401.
33. Dong C: Diversification of T-helper-cell lineages: finding the family root of IL-17-producing cells. Nat Rev Immunol 2006;6:329-333.
34. Leibundgut-Landmann S, Gross O, Robinson MJ, Osorio F, Slack EC, Tsoni SV, Schweighoffer E, Tybulewicz V, Brown GD, Ruland J, Reis ESC: Syk- and CARD9-dependent coupling of innate immunity to the induction of T-helper cells that produce interleukin-17. Nat Immunol 2007;8:630-638.
35. Zelante T, De Luca A, Bonifazi P, Montagnoli C, Bozza S, Moretti S, Belladonna ML, Vacca C, Conte C, Bistoni F, Puccetti P, Kastelein RA, Kopf M, Romani L: The Th17 pathway promote inflammation and impairs antifungal immune resistance. Eur J Immunol 37:2695-2706.
36. De Luca A, Montagnoli C, Zelante T, Bonifazi P, Bozza S, Moretti S, D'Angelo C, Vacca C, Boon L, Bistoni F, Puccetti P, Fallarino F, Romani L: Functional yet balanced reactivity to Candida albicans requires both TRIF and MyD88 and IDO-dependent inhibition of Rorc. J Immunol 2007;179:5999-6008.
37. Huang W, Na L, Fidel PL, Schwarzenberger P: Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice. J Infect Dis 2004;190:624-631.
38. Bozza S, Fallarino F, Pitzurra L, Zelante T, Montagnoli C, Bellocchio S, Mosci P, Vacca C, Puccetti P, Romani L: A crucial role for tryptophan catabolism at the host/Candida albicans Interface. J Immunol 2005;174:2910-2918.
39. Montagnoli C, Fallarino F, Gaziano R, Bozza S, Bellocchio S, Zelante T, Kurup WP, Pitzurra L, Puccetti P, Romani L: Immunity and tolerance to Aspergillus involve functionally distinct regulatory T cells and tryptophan catabolism. J Immunol 2006;176:1712-1723.
40. Linden A, Laan M, Anderson GP: Neutrophils, interleukin-17A and lung disease. Eur Respir J 2005;25:159-172.
41. Nakae S, Komiyama Y, Nambu A, Sudo K, Iwase M, Homma I, Sekikawa K, Asano M, Iwakura Y: Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity 2002;17:375-387.
42. Herrick CA, Bottomly K: To respond or not to respond: T cells in allergic asthma. Nat Rev Immunol 2003;3:405-412.
43. Lima HC: Role of regulatory T cells in the development of skin diseases. An Bras Dermatol 2006;81:269-281.
44. O'Garra A, Vieira P: Regulatory T cells and mechanisms of immune system control. Nat Med 2004;10:801-805.
45. Mucida D, Park Y, Kim G, Turovskaya O, Scott I, Kronenberg M, Cheroutre H: Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science 2007;317:256-260.
46. Bettelli E, Oukka M, Kuchroo VK: Th-17 cells in the circle of immunity and autoimmunity. Nat Immunol 2007;8:345-350.
47. Ryan KR, Lawson CA, Lorenzi AR, Arkwright PD, Isaacs JD, Lilic D: CD4+CD25+ T-regulatory cells are decreased in patients with autoimmune polyendocrinopathy candidiasis ectodermal dystrophy. J Allergy Clin Immunol 2005;116:1158-1159.
48. Montagnoli C, Bacci A, Bozza S, Gaziano R, Mosci P, Sharpe AH, Romani L: B7/CD28-dependent CD4+CD25+ regulatory T cells are essential components of the memory-protective immunity to Candida albicans. J Immunol 2002;169:6298-6308.
49. Puccetti P, Grohmann U: IDO and regulatory T cells: a role for reverse signaling and non-canonical NF-κB activation. Nat Rev Immunol 2007;7:817-823.
50. Fallarino F, Grohmann U, Hwang KW, Orabona C, Vacca C, Bianchi R, Belladonna ML, Fioretti MC, Alegre ML, Puccetti P: Modulation of tryptophan catabolism by regulatory T cells. Nat Immunol 2003;4:1206-1212.
51. Grohmann U, Volpi C, Fallarino F, Bozza S, Bianchi R, Vacca C, Orabona C, Belladonna ML, Ayroldi E, Nocentini G, Boon L, Bistoni F, Fioretti MC, Romani L, Riccardi C, Puccetti P: Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy. Nat Med 2007;13:579-586.
52. Judson MA, Stevens DA: Current pharmacotherapy of allergic bronchopulmonary aspergillosis. Expert Opin Pharmacother 2001;2:1065-1071.
53. Wills-Karp M, Santeliz J, Karp CL: The germless theory of allergic disease: revisiting the hygiene hypothesis. Nat Rev Immunol 2001;1:69-75.
54. Bach JF: The effect of infections on susceptibility to autoimmune and allergic diseases. N Engl J Med 2002;347:911-920.
55. Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R: Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 2004;118:229-241.
56. Neish AS, Gewirtz AT, Zeng H, Young AN, Hobert ME, Karmali V, Rao AS, Madara JL: Prokaryotic regulation of epithelial responses by inhibition of IκB-α ubiquitination. Science 2000;289:1560-1563.
57. Gurtner GJ, Newberry RD, Schloemann SR, McDonald KG, Stenson WF: Inhibition of indoleamine 2,3-dioxygenase augments trinitrobenzene sulfonic acid colitis in mice. Gastroenterology 2003;125:1762-1773.
58. Padrid PA, Mathur M, Li X, Herrmann K, Qin Y, Cattamanchi A, Weinstock J, Elliott D, Sperling AI, Bluestone JA: CTLA4Ig inhibits airway eosinophilia and hyperresponsiveness by regulating the development of Th1/Th2 subsets in a murine model of asthma. Am J Respir Cell Mol Biol 1998;18:453-462.
59. Hayashi T, Beck L, Rossetto C, Gong X, Takikawa O, Takabayashi K, Broide DH, Carson DA, Raz E: Inhibition of experimental asthma by indoleamine 2,3-dioxygenase. J Clin Invest 2004;114:270-279.
60. Von Bubnoff D, Fimmers R, Bogdanow M, Matz H, Koch S, Bieber T: Asymptomatic atopy is associated with increased indoleamine 2,3-dioxygenase activity and interleukin-10 production during seasonal allergen exposure. Clin Exp Allergy 2004;34:1056-1063.
61. Hessel EM, Chu M, Lizcano JO, Chang B, Herman N, Kell SA, Wills-Karp M, Coffman RL: Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction. J Exp Med 2005;202:1563-1573.
62. Zaph C, Troy AE, Taylor BC, Berman-Booty LD, Guild KJ, Du Y, Yost EA, Gruber AD, May MJ, Greten FR, Eckmann L, Karin M, Artis D: Epithelial-cell- intrinsic IKK-β expression regulates intestinal immune homeostasis. Nature 2007;446:552-556.