Protective tolerance to fungi: the role of IL-10 and tryptophan catabolism

Trends in Microbiology

Volumn 14, Issue 4, 2006, Pages 183-189

  Romani, Luigina ^a   Puccetti, Paolo ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; INTERLEUKIN 10; INTERLEUKIN 10 AGONIST; INTERLEUKIN 10 ANTAGONIST; INTERLEUKIN 4; TRANSFORMING GROWTH FACTOR BETA; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ASPERGILLOSIS; CANDIDIASIS; CATABOLISM; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CYTOKINE PRODUCTION; DRUG MECHANISM; HOST PATHOGEN INTERACTION; HUMAN; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; IMMUNOREACTIVITY; IMMUNOREGULATION; INFECTION PREVENTION; MYCOSIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REVIEW; SIGNAL TRANSDUCTION; TH1 CELL;

FUNGI; HUMANS; IMMUNE TOLERANCE; INTERFERON TYPE II; INTERLEUKIN-10; MYCOSES; T-LYMPHOCYTES, REGULATORY; TRYPTOPHAN;

FUNGI;

EID: 33645984274     PISSN: 0966842X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tim.2006.02.003     Document Type: Review

References (38)

1. Romani L. Immunity to fungal infections. Nat. Rev. Immunol. 4 (2004) 1-23
2. O'Garra A., and Vieira P. Regulatory T cells and mechanisms of immune system control. Nat. Med. 10 (2004) 801-805
3. Mills K.H. Regulatory T cells: friend or foe in immunity to infection?. Nat. Rev. Immunol. 4 (2004) 841-855
4. Belkaid Y., and Rouse B.T. Natural regulatory T cells in infectious disease. Nat. Immunol. 6 (2005) 353-360
5. No authors listed. Essence of harmony. Nat. Immunol. 6 (2005) 325
6. Balloy V., et al. Differences in patterns of infection and inflammation for corticosteroid treatment and chemotherapy in experimental invasive pulmonary aspergillosis. Infect. Immun. 73 (2005) 494-503
7. Mencacci A., et al. IL-10 is required for development of protective Th1 responses in IL-12-deficient mice upon Candida albicans infection. J. Immunol. 161 (1998) 6228-6237
8. Ausiello C.M., et al. Cytokine gene expression in human peripheral blood mononuclear cells stimulated by mannoprotein constituents from Candida albicans. Infect. Immun. 61 (1993) 4105-4111
9. Hebart H., et al. Analysis of T-cell responses to Aspergillus fumigatus antigens in healthy individuals and patients with hematologic malignancies. Blood 100 (2002) 4521-4528
10. Qureshi M.H., et al. IL-10 modulates host responses and lung damage induced by Pneumocystis carinii infection. J. Immunol. 170 (2003) 1002-1009
11. Brouard J., et al. Influence of interleukin-10 on Aspergillus fumigatus infection in patients with cystic fibrosis. J. Infect. Dis. 191 (2005) 1988-1991
12. Li L., et al. Cellular immune suppressor activity resides in lymphocyte cell clusters adjacent to granulomata in human coccidioidomycosis. Infect. Immun. 73 (2005) 3923-3928
13. Romani L. Immunity to Candida albicans: Th1, Th2 cells and beyond. Curr. Opin. Microbiol. 2 (1999) 363-367
14. Deepe Jr. G.S. Immune response to early and late Histoplasma capsulatum infections. Curr. Opin. Microbiol. 3 (2000) 359-362
15. Trinchieri G. Regulatory role of T cells producing both interferon γ and interleukin 10 in persistent infection. J. Exp Med. 194 (2001) F53-F57
16. Bozza S., et al. A crucial role for tryptophan catabolism at the host-Candida albicans interface. J. Immunol. 174 (2005) 2910-2918
17. Fallarino F., et al. Modulation of tryptophan catabolism by regulatory T cells. Nat. Immunol. 4 (2003) 1206-1212
18. Hori S., et al. CD25+CD4+ regulatory T cells suppress CD4+ T cell-mediated pulmonary hyperinflammation driven by Pneumocystis carinii in immunodeficient mice. Eur. J. Immunol. 32 (2002) 1282-1291
19. Montagnoli C., et al. B7/CD28-dependent CD4+CD25+ regulatory T cells are essential components of the memory-protective immunity to Candida albicans. J. Immunol. 169 (2002) 6298-6308
20. Montagnoli C., et al. Immunity and tolerance to Aspergillus involve functionally distinct regulatory T cells and tryptophan catabolism. J. Immunol. 176 (2006) 1712-1723
21. Netea M.G., et al. Toll-like receptors as an escape mechanism from the host defense. Trends Microbiol. 12 (2004) 484-488
22. Fidel Jr. P.L. The protective immune response against vaginal candidiasis: lessons learned from clinical studies and animal models. Int. Rev. Immunol. 21 (2002) 515-548
23. Carvalho L.P., et al. Downregulation of IFN-γ production in patients with recurrent vaginal candidiasis. J. Allergy Clin. Immunol. 109 (2002) 102-105
24. Lilic D. New perspectives on the immunology of chronic mucocutaneous candidiasis. Curr. Opin. Infect. Dis. 15 (2002) 143-147
25. Liston A., et al. Aire regulates negative selection of organ-specific T cells. Nat. Immunol. 4 (2003) 350-354
26. Akbari O., et al. Role of regulatory T cells in allergy and asthma. Curr. Opin. Immunol. 15 (2003) 627-633
27. Alyanakian M.A., et al. Diversity of regulatory CD4+T cells controlling distinct organ-specific autoimmune diseases. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 15806-15811
28. Grohmann U., et al. Tolerance, DCs and tryptophan: much ado about IDO. Trends Immunol. 24 (2003) 242-248
29. Romani L., et al. Fungi, dendritic cells and receptors: a host perspective of fungal virulence. Trends Microbiol. 10 (2002) 508-514
30. Gurtner G.J., et al. Inhibition of indoleamine 2,3-dioxygenase augments trinitrobenzene sulfonic acid colitis in mice. Gastroenterology 125 (2003) 1762-1773
31. Umetsu D.T., et al. Asthma: an epidemic of dysregulated immunity. Nat. Immunol. 3 (2002) 715-720
32. Heaton T., et al. An immunoepidemiological approach to asthma: identification of in-vitro T-cell response patterns associated with different wheezing phenotypes in children. Lancet 365 (2005) 142-149
33. Hansen G., et al. Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation. J. Clin. Invest. 103 (1999) 175-183
34. McGuirk P., and Mills K.H. Pathogen-specific regulatory T cells provoke a shift in the Th1/Th2 paradigm in immunity to infectious diseases. Trends Immunol. 23 (2002) 450-455
35. Noverr M.C., and Huffnagle G.B. Does the microbiota regulate immune responses outside the gut?. Trends Microbiol. 12 (2004) 562-568
36. Perruccio K., et al. Prospects for dendritic cell vaccination against fungal infections in hematopoietic transplantation. Blood Cells Mol. Dis. 33 (2004) 248-255
37. Scheckelhoff M., and Deepe Jr. G.S. A deficiency in γ-interferon or interleukin-10 modulates T-cell-dependent responses to heat shock protein 60 from Histoplasma capsulatum. Infect. Immun. 73 (2005) 2129-2134
38. Bluestone J.A. Regulatory T-cell therapy: is it ready for the clinic?. Nat. Rev. Immunol. 5 (2005) 343-349