Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis

Journal of Allergy and Clinical Immunology

Volumn 119, Issue 5, 2007, Pages 1210-1217

  Guttman Yassky, Emma ^a   Lowes, Michelle A ^a   Fuentes Duculan, Judilyn ^a   Whynot, Julia ^a   Novitskaya, Inna ^a   Cardinale, Irma ^a   Haider, Asifa ^a   Khatcherian, Artemis ^a   Carucci, John A ^b   Bergman, Reuven ^c   Krueger, James G ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c RAMBAM MEDICAL CENTER   (Israel)

Author keywords

Atopic dermatitis; inflammatory dendritic epidermal cells; myeloid DCs; plasmacytoid DCs; psoriasis; TIP DCs

Indexed keywords

CHEMOKINE; CYTOKINE;

ADOLESCENT; ADULT; AGED; ANTIGEN PRESENTATION; ARTICLE; ATOPIC DERMATITIS; BONE MARROW CELL; CLINICAL ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; DNA MICROARRAY; FEMALE; GENE EXPRESSION; HUMAN; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PSORIASIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN BIOPSY; TH1 CELL; TH2 CELL;

ADOLESCENT; ADULT; AGED; CYTOKINES; DENDRITIC CELLS; DERMATITIS, ATOPIC; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PSORIASIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SKIN; T-LYMPHOCYTES;

EID: 34247532495     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2007.03.006     Document Type: Article

References (29)

1. Krueger J.G. The immunologic basis for the treatment of psoriasis with new biologic agents. J Am Acad Dermatol 46 (2002) 1-23 quiz 23-6
2. Leung D.Y., and Bieber T. Atopic dermatitis. Lancet 361 (2003) 151-160
3. Ong P.Y., and Leung D.Y. Immune dysregulation in atopic dermatitis. Curr Allergy Asthma Rep 6 (2006) 384-389
4. Homey B., Steinhoff M., Ruzicka T., and Leung D.Y. Cytokines and chemokines orchestrate atopic skin inflammation. J Allergy Clin Immunol 118 (2006) 178-189
5. de Jongh G.J., Zeeuwen P.L., Kucharekova M., Pfundt R., van der Valk P.G., Blokx W., et al. High expression levels of keratinocyte antimicrobial proteins in psoriasis compared with atopic dermatitis. J Invest Dermatol 125 (2005) 1163-1173
6. Wollenberg A., Kraft S., Hanau D., and Bieber T. Immunomorphological and ultrastructural characterization of Langerhans cells and a novel, inflammatory dendritic epidermal cell (IDEC) population in lesional skin of atopic eczema. J Invest Dermatol 106 (1996) 446-453
7. Novak N., and Bieber T. The role of dendritic cell subtypes in the pathophysiology of atopic dermatitis. J Am Acad Dermatol 53 (2005) S171-S176
8. Wollenberg A., Mommaas M., Oppel T., Schottdorf E.M., Gunther S., and Moderer M. Expression and function of the mannose receptor CD206 on epidermal dendritic cells in inflammatory skin diseases. J Invest Dermatol 118 (2002) 327-334
9. Angel C.E., George E., Brooks A.E., Ostrovsky L.L., Brown T.L., and Dunbar P.R. Cutting edge: CD1a+ antigen-presenting cells in human dermis respond rapidly to CCR7 ligands. J Immunol 176 (2006) 5730-5734
10. Stary G., Bangert C., Stingl G., and Kopp T. Dendritic cells in atopic dermatitis: expression of FcepsilonRI on two distinct inflammation-associated subsets. Int Arch Allergy Immunol 138 (2005) 278-290
11. Wollenberg A., Wagner M., Gunther S., Towarowski A., Tuma E., Moderer M., et al. Plasmacytoid dendritic cells: a new cutaneous dendritic cell subset with distinct role in inflammatory skin diseases. J Invest Dermatol 119 (2002) 1096-1102
12. Gilliet M., Conrad C., Geiges M., Cozzio A., Thurlimann W., Burg G., et al. Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors. Arch Dermatol 140 (2004) 1490-1495
13. Lowes M.A., Chamian F., Abello M.V., Fuentes-Duculan J., Lin S.L., Nussbaum R., et al. Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a). Proc Natl Acad Sci U S A 102 (2005) 19057-19062
14. Soumelis V., Reche P.A., Kanzler H., Yuan W., Edward G., Homey B., et al. Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP. Nat Immunol 3 (2002) 673-680
15. Watanabe N., Hanabuchi S., Marloie-Provost M.A., Antonenko S., Liu Y.J., and Soumelis V. Human TSLP promotes CD40 ligand-induced IL-12 production by myeloid dendritic cells but maintains their Th2 priming potential. Blood 105 (2005) 4749-4751
16. Yoo J., Omori M., Gyarmati D., Zhou B., Aye T., Brewer A., et al. Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin. J Exp Med 202 (2005) 541-549
17. Zhou X., Krueger J.G., Kao M.C., Lee E., Du F., Menter A., et al. Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array. Physiol Genomics 13 (2003) 69-78
18. Haider A.S., Peters S.B., Kaporis H., Cardinale I., Fei J., Ott J., et al. Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia. J Invest Dermatol 126 (2006) 869-881
19. Liu Y.J. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell 106 (2001) 259-262
20. Rissoan M.C., Soumelis V., Kadowaki N., Grouard G., Briere F., de Waal Malefyt R., et al. Reciprocal control of T helper cell and dendritic cell differentiation. Science 283 (1999) 1183-1186
21. Penna G., Vulcano M., Sozzani S., and Adorini L. Differential migration behavior and chemokine production by myeloid and plasmacytoid dendritic cells. Hum Immunol 63 (2002) 1164-1171
22. Nomura I., Goleva E., Howell M.D., Hamid Q.A., Ong P.Y., Hall C.F., et al. Cytokine milieu of atopic dermatitis, as compared to psoriasis, skin prevents induction of innate immune response genes. J Immunol 171 (2003) 3262-3269
23. Nomura I., Gao B., Boguniewicz M., Darst M.A., Travers J.B., and Leung D.Y. Distinct patterns of gene expression in the skin lesions of atopic dermatitis and psoriasis: a gene microarray analysis. J Allergy Clin Immunol 112 (2003) 1195-1202
24. Kato Y., Pawankar R., Kimura Y., and Kawana S. Increased expression of RANTES, CCR3 and CCR5 in the lesional skin of patients with atopic eczema. Int Arch Allergy Immunol 139 (2006) 245-257
25. Park C.W., Lee B.H., Han H.J., Lee C.H., and Ahn H.K. Tacrolimus decreases the expression of eotaxin, CCR3, RANTES and interleukin-5 in atopic dermatitis. Br J Dermatol 152 (2005) 1173-1181
26. Tanaka K., Roberts M.H., Yamamoto N., Sugiura H., Uehara M., and Hopkin J.M. Upregulating promoter polymorphisms of RANTES relate to atopic dermatitis. Int J Immunogenet 33 (2006) 423-428
27. Shortman K., and Naik S.H. Steady-state and inflammatory dendritic-cell development. Nat Rev Immunol 7 (2007) 19-30
28. Serbina N.V., Salazar-Mather T.P., Biron C.A., Kuziel W.A., and Pamer E.G. TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection. Immunity 19 (2003) 59-70
29. MacDonald K.P., Munster D.J., Clark G.J., Dzionek A., Schmitz J., and Hart D.N. Characterization of human blood dendritic cell subsets. Blood 100 (2002) 4512-4520