In-vivo mathematical study of co-infection dynamics of HIV-1 and Mycobacterium tuberculosis

Journal of Biological Systems

Volumn 16, Issue 3, 2008, Pages 357-394

  Magombedze, Gesham ^a   Garira, Winston ^a   Mwenje, Eddie ^a  

^a NATIONAL UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Zimbabwe)

Author keywords

CD4+ helper T cells; Co infection; Human Immunodeficiency Virus (HIV); Mathematical modeling; Mycobacterium tuberculosis (Mtb)

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MYCOBACTERIUM TUBERCULOSIS;

EID: 52249101534     PISSN: 02183390     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0218339008002551     Document Type: Article

References (32)

1. Kirschner D, Dynamics of co-infection with M. tuberculosis and HIV-1, Theor Popul Biol 55:94-109, 1999.
2. Weiden M et al., Differentiation of monocytes to macrophages switches the Mycobacterium tuberculosis effect on HIV-1 replication from stimulation to inhibition: modulation of interferon response and CCAAT/enhancer binding protein β expression, J Immunol 165:2028-2039, 2000.
3. Honda Y et al., Type I interferon induces inhibitory 16-kD CCAAT/enhancer binding protein (C/EBP)β, repressing the HIV-1 long terminal repeat in macrophages: pulmonary tuberculosis alters C/EBP expression, enhancing HIV-1 replication, J Exp Med 188(7):1255-1265, 1998.
4. Kaufmanns SH and Schaible UE, A dangerous liaison between two major killers: Mycobacterium tuberculosis and HIV target dendritic cells through DC-SIGN. Commentry, J Exp Med 197:121-127, 7-17, 2003.
5. Kirschner D, Using mathematics to understanding HIV immune dynamics, Not AIMS 43:191-202, 1996.
6. Janeway AC, Travers P, Walport M, Shlomchik JM, Immuno Biology: The Immune System in Health and Disease, Garland Science Publishing, 2005.
7. Stevenson M, HIV-1 pathogenesis: review, Nat Med 9(7):853-860, 2003.
8. Kaplan D, Sieg S, Role of the Fas/Fas ligand apoptotic pathway in human immunodeficiency virus type 1 disease, J Virol 72(8):6279-6282, 1998.
9. Raja, A, Immunology of tuberculosis: review article, Indian J Med Bes 120:213-232, 2004.
10. Schluger NW, Rom WN, The host immune response to tuberculosis: state of the art, Am J Respir Crit Care Med 157:679-691, 1998.
11. Flynn JL, Immunology of tuberculosis and implications in vaccine developments, Tuberculosis 84:93-101, 2004.
12. Wigginton JE, Kischner D, A model to predict cell mediated immune regulatory mechanisms during human infection with Mycobacterium tuberculosis, J Immunol 166(3):1951-1967, 2001.
13. Schluger NW, Recent advances in our understanding of the human host responses to tuberculosis: review, Respir Res 2:157-163, 2001.
14. Rook GAW, Seah G, Ustianowski A, M. tuberculosis: immunology and vaccination, Eur Respir 17:537-557, 2001.
15. Marino S, Kirschner D, The human immune response to Mycobacterium tuberculosis in lung and lymph node, J Theor Biol 227:463-486, 2004.
16. Stenger S et al., An anti-microbial activity of cytotoxic T cells mediated by granulysin, Science 282:121-125, 1998.
17. Stenger S et al., Differential effects of cytolytic T cell subsets on intracellular infection, Science 276:1684-1687, 1997.
18. Hoshino Y et al., Maximal HIV- replication in alveolar macrophages during tuberculosis requires both lymphocyte contact and cytokines, J Exp Med 195(4):495-505, 2002.
19. Hoshino Y et al., Mycobacterium tuberculosis-induced CXR4 and chemokine expression leads to preferential X4 HIV-lreplication in human macrophages, J Immunol 172:6251-6258, 2004.
20. Yi Y et al., Role of CXCR4 in cell-cell fusion and infection of monocyte derived macrophages by primary human immunodeficiency virus type 1 (HIV-1) strains: two distinct mechanisms of HIV-1 dual tropism, J Virol 73(9):7117-7125, 1999.
21. Raju B et al., In situ activation of helper T cells in the lung, Infect Immun 69(8): 4790-4798, 2001.
22. Magombedze G, Garira W, Mwenje E, Modelling the human immune response mechanisms to Mycobacterium tuberculosis infection in the lungs, MBE 3(4):661-682, 2006.
23. Flynn JL, Goldstein MM, Chan J, Triebold KJ, Pfeffer K, Lowenstein CJ et al., Tumor necrosis factor-a is required in the protective immune response against Mycobacterium tuberculosis in mice, Immunity 2:561-572, 1995.
24. 0 in models for infectious diseases in heterogeneous population, J Math Biol 28:365-382, 1990.
25. 0 its role on global stability, IMA 125:229-250, 2002.
26. Rosas Taraco AG et al., Mycobacterium tuberculosis upregulates coreceptors CCR-5 and CXCR4 while HIV modulates CD 14 favoring concurrent infection, AIDS Res Hum Retrovir 22(1):45-51, 2006.
27. Aquaro S et al., Macrophages and HIV infection: therapeutical approaches toward this strategic virus reservoir, Antiviral Res 55:209-225, 2002.
28. Moriuchi M, Moriuchi H, Turner W, Fauci AC, Exposure to bacterial products renders macrophages highly susceptible to T-tropic HIV-1, J Clin Invest 102(8):1540-1550, 1998.
29. Orenstein JN, The macrophage in HIV infection, Immunobiology 204:598-602, 2001.
30. Verani A, Gras G, Pancino, Macrophages and HIV-1: dangerous liaisons, Mol Immunol 42:195-212, 2005.
31. Serbina NV, Flynn JL, Early emergence of CD8+ T cells primed for production of Type 1 cytokenes in the lungs of Mycobacterium tuberculosis-infected mice, Infect Immunol 67:3980-3988, 1999.
32. Shiri T, Garira W, Musekwa SD, A two-strain HIV-1 mathematical model to assess the effects of chemotherapy on disease parameters, MBE 2:811-832, 2005.