Maximal HIV-1 replication in alveolar macrophages during tuberculosis requires both lymphocyte contact and cytokines

Journal of Experimental Medicine

Volumn 195, Issue 4, 2002, Pages 495-505

  Hoshino, Yoshihiko ^a   Nakata, Koh ^b   Hoshino, Satomi ^a   Honda, Yoshihiro ^c   Tse, Doris B ^a   Shioda, Tatsuo ^d   Rom, William N ^a   Weiden, Michael ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^c Sendai Kosei Hospital   (Japan)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

Cellular immunity; Costimulatory molecules; Derepression; Infection; Transcription factors

Indexed keywords

BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

ARTICLE; CELL INTERACTION; CELLULAR IMMUNITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN TISSUE; IMMUNE RESPONSE; LUNG ALVEOLUS MACROPHAGE; LUNG TUBERCULOSIS; PRIORITY JOURNAL; VIRUS CELL INTERACTION; VIRUS REPLICATION;

BLOTTING, WESTERN; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL ADHESION; CYTOKINES; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, VIRAL; HIV INFECTIONS; HIV LONG TERMINAL REPEAT; HIV-1; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE ACTIVATION; MACROPHAGES, ALVEOLAR; NF-KAPPA B; PROMOTER REGIONS (GENETICS); T-LYMPHOCYTES; TUBERCULOSIS; VIRAL LOAD; VIRUS REPLICATION;

EID: 0037128166     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20011614     Document Type: Article

References (24)

1. Low copy number and limited variability of proviral DNA in alveolar macrophages from HIV-1 infected patients: Evidence for genetic differences in HIV-1 between lung and blood macrophage populations
2. M. tuberculosis enhances human immunodeficiency virus-1 replication in the lung
3. Macrophages as a source of HIV during opportunistic infections
4. Accelerated course of human immunodeficiency virus infection after tuberculosis
5. Macrophage differentiation-specific expression of NF-IL6, a transcription factor for Interleukin-6
6. A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA
7. C/EBP-beta regulation of the tumor-necrosis-factor-alpha gene
8. Ras regulates the association of serum response factor and CCAAT/enhancer-binding protein beta
9. + T cells
10. NF IL-6-mediated transcriptional activation of the long terminal repeat of the human immunodeficiency virus type 1
11. Type I interferon induces inhibitory 16 kDa C/EBP-β repressing the HIV-1 LTR in macrophages: Pulmonary tuberculosis alters C/EBP expression enhancing HIV-1 replication
12. C/EBP proteins activate transcription from human immunodeficiency virus type 1 long terminal repeat in macrophages/monocytes
13. Mycobacterium toberculosis enhances HIV-1 replication by transcriptional activation at the long terminal repeat
14. Differentiation of monocytes to macrophages switches the Mycobacterium tuberculosis effect on HIV-1 replication from stimulation to inhibition: Modulation of interferon response and C/EBPβ expression
15. Induction of HIV-1 replication by allogeneic stimulation
16. Activation of infectious virus from latent human-immunodeficiency-virus infection of monocytes in vivo
17. Autocrine signals control CCAAT enhancer binding protein beta expression, localization, and activity in macrophages
18. Generation of truncated C/EBP beta isoforms by in vitro proteolysis
19. Translational control of C/EBP alpha and C/EBP beta isoform expression
20. Regulation of CCAAT/enhancer-binding protein-beta isoform synthesis by alternative translational initiation at multiple AUG start sites
21. C/EBP alpha regulates generation of C/EBP beta isoforms through activation of specific proteolytic cleavage
22. Tuberculosis in HIV-positive patients: Cellular response and immune activation in the lung
23. Microglial production of TNF-alpha is induced by activated T Lymphocytes - Involvement of VLA-4 and inhibition by Interferon beta-1b
24. Mechanisms of IL-10 production in human microglia-t cell interaction