Endotoxin causes pulmonary hypertension by upregulating smooth muscle endothelin type-B receptors: Role of aldose reductase

Shock

Volumn 30, Issue 2, 2008, Pages 189-196

  Dschietzig, Thomas ^a   Alexiou, Kosta ^b   Richter, Christoph ^a   Bobzin, Martin ^a   Baumann, Gert ^a   Stangl, Karl ^a   Brunner, Friedrich ^c  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b University Heart Center Dresden   (Germany)

^c UNIVERSITY OF GRAZ   (Austria)

Author keywords

Aldose reductase; Endothelin receptors; Endothelin 1; Endothelium; Endotoxin; Lung; Pulmonary hypertension; Vascular smooth muscle

Indexed keywords

ALDEHYDE REDUCTASE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR ANTAGONIST; ENDOTOXIN; MESSENGER RNA; SORBINIL; ZOPOLRESTAT; BENZOTHIAZOLE DERIVATIVE; IMIDAZOLIDINE DERIVATIVE; PHTHALAZINE DERIVATIVE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROL GROUP; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; ENDOTOXEMIA; GENE EXPRESSION; LUNG; LUNG BLOOD VESSEL; LUNG PERFUSION; LUNG VASCULAR RESISTANCE; MALE; NONHUMAN; PULMONARY HYPERTENSION; RAT; RECEPTOR UPREGULATION; SMOOTH MUSCLE; SMOOTH MUSCLE FIBER; ACUTE DISEASE; ANIMAL; BIOSYNTHESIS; CELL CULTURE; COMPARATIVE STUDY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; LUNG WEDGE PRESSURE; METABOLISM; PATHOPHYSIOLOGY; PERFUSION; PHYSIOLOGY; UPREGULATION; WISTAR RAT;

ACUTE DISEASE; ALDEHYDE REDUCTASE; ANIMALS; BENZOTHIAZOLES; CELLS, CULTURED; ENDOTOXINS; HYPERTENSION, PULMONARY; IMIDAZOLIDINES; MALE; MUSCLE, SMOOTH; PERFUSION; PHTHALAZINES; PULMONARY WEDGE PRESSURE; RATS; RATS, WISTAR; RECEPTOR, ENDOTHELIN B; UP-REGULATION;

EID: 52149115137     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e318160f03b     Document Type: Article

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