Bosentan-improved cardiopulmonary vascular performance and increased plasma levels of endothelin-1 in porcine endotoxin shock

British Journal of Pharmacology

Volumn 118, Issue 3, 1996, Pages 617-626

  Weitzberg, Eddie ^a   Hemsén, Anette ^b   Rudehill, Anders ^a   Modin, Agnes ^b   Wanecek, Michael ^a   Lundberg, Jan M ^b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Big endothelin; Bosentan; Endothelin; Endothelin receptor antagonist; Intestinal blood flow; Lipopolysaccharide; Noradrenaline; Pulmonary hypertension; Septic shock; Splenic blood flow

Indexed keywords

BIG ENDOTHELIN 1; BOSENTAN; ENDOTHELIN 1; ENDOTHELIN RECEPTOR ANTAGONIST; LIPOPOLYSACCHARIDE; MESSENGER RNA; PROTEIN PRECURSOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; ENDOTOXEMIA; FEMALE; HEART OUTPUT; HEART RATE; HEMODYNAMICS; INTESTINE BLOOD FLOW; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY BLOOD FLOW; LUNG ARTERY PRESSURE; LUNG HEMODYNAMICS; LUNG VASCULAR RESISTANCE; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; SEPTIC SHOCK; SPLEEN BLOOD FLOW; SWINE; SYSTEMIC VASCULAR RESISTANCE;

EID: 0029894226     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15446.x     Document Type: Article

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