Inhibiting gene expression of α3 nicotinic receptor in SH-SY5Y cells with the effects on APP metabolism and antioxidation in Alzheimer's disease

Neurochemistry International

Volumn 53, Issue 5, 2008, Pages 112-117

  Tang, Zhi ^a   An, Yu ^a   Qi, Xiao Lan ^a   Xiao, Yan ^a   Shan, Ke Ren ^a   Guan, Zhi Zhong ^a  

^a GUIZHOU MEDICAL UNIVERSITY   (China)

Author keywords

3 Nicotinic acetylcholine receptor; Amyloid precursor protein; Oxidative stress; RNA interference; SH SY5Y cells

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALPHA AMYLOID PRECURSOR PROTEIN; ALPHA SECRETASE; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; GLUTATHIONE PEROXIDASE; MESSENGER RNA; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA3; SMALL INTERFERING RNA; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENE REPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIPID PEROXIDATION; NEUROBLASTOMA CELL; NEUROPROTECTION; NEUROTOXICITY; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; SPECTROPHOTOMETRY; WESTERN BLOTTING;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; CELL LINE, TUMOR; GLUTATHIONE PEROXIDASE; HUMANS; LIPID PEROXIDATION; OXIDATIVE STRESS; OXIDOREDUCTASES; PEPTIDE FRAGMENTS; PROTEIN PRECURSORS; RECEPTORS, NICOTINIC; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 52049126181     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2008.06.010     Document Type: Article

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