The antithrombotic effect of Borneol related to its anticoagulant property

American Journal of Chinese Medicine

Volumn 36, Issue 4, 2008, Pages 719-727

  Li, Yan Hong ^a   Sun, Xiao Ping ^a   Zhang, Yin Qing ^a   Wang, Ning Sheng ^a  

^a GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Antithrombosis; Borneol; Clotting time; Platelet aggregation

Indexed keywords

ACETYLSALICYLIC ACID; BORNEOL; PLACEBO;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICOAGULATION; ARTERIOVENOUS SHUNT; ARTICLE; BLOOD CLOTTING; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG MEGADOSE; DRUG RESPONSE; FIBRINOLYSIS; LOW DRUG DOSE; MALE; NONHUMAN; PROTHROMBIN TIME; RAT; THROMBIN TIME; THROMBOCYTE AGGREGATION; VEIN THROMBOSIS;

ANIMALS; ANTICOAGULANTS; BLOOD COAGULATION; BORNANES; DISEASE MODELS, ANIMAL; FIBRINOLYSIS; FIBRINOLYTIC AGENTS; MALE; PLATELET AGGREGATION; PROTHROMBIN TIME; RATS; RATS, WISTAR; THROMBIN TIME; VENOUS THROMBOSIS;

EID: 52049111393     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X08006181     Document Type: Article

References (25)

1. Al-Jishi, S.A. and B. Abuo Hozaifa. Effect of Nigella sativa on blood hemostatic function in rats. J. Ethnopharmacol. 85: 7-14, 2003.
2. Born, G.V.R. and M.J. Cross. Cross biochemistry of platelets. Lancet 281: 168, 1963.
3. Chaer, R.A. and J.A. Graham. Mureebe L. Platelet function and pharmacologic inhibition. Vasc. Endovascular. Surg. 40: 261-267, 2006.
4. Chapman, M.J. From pathophysiology to targeted therapy for atherothrombosis: A role for the combination of statin and aspirin in secondary prevention. Pharmacol. Ther. 113: 184-196, 2007.
5. Fang, Y.Q., Y.Y. Zhou, L. Li, G. Wei and S.F. Lin. Effects of FangXiang KaiQiao drugs and QieTan drugs on CNS excitability. Res. Tradit. Chin. Med. 18: 40-42, 2002.
6. Granger, R.E., E.L. Campbell and G.A. Johnston. (+)- and (-)-borneol: efficacious positive modulators of GABA action at human recombinant alpha1 beta2gamma2L GABA (A) receptors. Biochem. Pharmacol. 69: 1101-1111, 2005.
7. Green, M.D., C.D. King, B. Mojarrabi, P.I. Mackenzie and T.R. Tephly. Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP- glucuronosyltransferase 1A3. Drug Metab. Dispos. 26: 507-512, 1998.
8. Guo, J., H. Meng, L.L. Wang, L. Zhang, X. Huang and R. Xu. Effect of blood drug level change of Borneol in Suxiaojiuxin pill on patients with myocardial ischemia. Med. J. Int. Tradit. Chin. West. Med. 13: 2387-2402, 2004.
9. A and glycerin receptor currents by menthol and related monoterpenoids. Eur. J. Pharmacol. 506: 9-16, 2004.
10. Kim, M.S. and K.A. Lee. Antithrombotic activity of methanolic extract of Usnea longissima. Phytother. Res. 19: 1061-1064, 2005.
11. Kim, M.S. and K.A. Lee. Antithrombotic activity of methanolic extract of Umbilicaria esculenta. J. Ethnopharmacol. 105: 342-345, 2006.
12. Kovacs, I.B., D.A. Gorog and J. Yamamoto. Enhanced spontaneous thrombolysis: A new therapeutic challenge. J. Thromb. Thrombolysis 21: 221-227, 2006.
13. Li, W.R., L.M. Yao, S.Q. Mi and N.S. Wang. The effect of borneol on level of HA and 5-HT in rat's hypothalamus. Zhong Yao Cai 27: 937-939, 2004.
14. Li Lin, A., N. Shangari, T.S. Chan, D. Remirez and P.J. O'Brien. Herbal monoterpene alcohols inhibit propofol metabolism and prolong anesthesia time. Life Sci. 79: 21-29, 2006.
15. Lorrain, J., L. Millet, I. Lechaire, S. Lochot, P. Ferrari, C. Visconte, M. Sainte-Marie, C. Lunven, C.N. Berry, P. Schaeffer, J.M. Herbert and S.E. O'Connor. Antithrombotic properties of SSR182289A, a new, orally active thrombin inhibitor. J. Pharmacol. Exp. Ther. 304: 567-574, 2003.
16. Mosnier, L.O. and B.N. Bouma. Regulation of fibrinolysis by thrombin activatable fibrinolysis inhibitor, an unstable carboxypeptidase B that unites the pathways of coagulation and fibrinolysis. Arterioscler. Thromb. Vasc. Biol. 26: 2445-2453, 2006.
17. Park, T.J., Y.S. Park, T.G. Lee, L. Ha and K.T. Kim. Inhibition of acetylcholine-mediated effects by borneol. Biochem. Pharmacol. 65: 83-90, 2003.
18. Benet, L.Z., D.L. Kroetz and L.B. Sheiner. Pharmacokinetics: The dynamics of drug absorption, distribution, and elimination. In: Goodman, L.S., L.E. Limbird, P.B. Milinoff, R.W. Ruddon and A.G. Gilman (eds.), Goodman & Gilman's. The Pharmacological Basis of Therapeutics, 9th ed. McGraw-Hill, New York, 1996.
19. Sato, K., T. Kawasaki, N. Hisamichi, Y. Taniuchi, F. Hirayama, H. Koshio, M. Ichihara and Y. Matsumoto. Antithrombotic effects of YM-60828 in three thrombosis models in guinea pigs. Eur. J. Pharmacol. 350: 87-91, 1998.
20. Tian, H., J. Ou, S.C. Strom and R. Venkataramanan. Activity and expression of various isoforms of uridine diphosphate glucuronosyltransferase are differentially regulated during hepatic regeneration in rats. Pharm. Res. 22: 2007-2015, 2005.
21. Verbeuren, T.J. Experimental models of thrombosis and atherosclerosis. Therapie 61: 379-387, 2005.
22. Wang, Y., Y.M. Gao and B.L. Zhang. Action and dose-effect study of borneol in the Danshen dropping pills. Zhong Gao Yao 35: 672-673, 2004.
23. Yan, Z., P. Liu, J. Zhang, C. Wan, T. Feng and W. Zhou. Gas chromatographic determination of camphora, menthol, isoborneol and borneol in Guanxingao. Se Pu 16: 411-413, 1998.
24. Yuk, D.Y, C.K. Ryu, J.T. Hong, K.H. Chung, W.S. Kang, Y. Kim, H.S. Yoo, M.K. Lee, C.K. Lee and Y.P. Yun. Antithrombotic and antiplatelet activities of 2-chloro-3-[4-(ethylcarboxy)-phenyl]-amino-1, 4-naphthoquinone (NQ12), a newly synthesized 1,4-naphthoquinone derivative. Biochem. Pharmacol. 60: 1001-1008, 2000.
25. Zhang, J.J., Z.Y. Zhu, J. Zhang and S.J. Gu. The observation on therapeutic efficacy of antihyperthermal and revival effects of Xingnaojing injection in treatment for severe craniocerebral injuries. Int. Tradit. Chin. West. Pract. Crit. Care Med. 6: 5-7, 1999.