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Volumn 350, Issue 1, 1998, Pages 87-91

Antithrombotic effects of YM-60828 in three thrombosis models in guinea pigs

Author keywords

Arterial thrombosis; Bleeding time; Factor Xa inhibitor; Venous thrombosis; YM 60828

Indexed keywords

[N [4 [(1 ACETIMIDOYL 4 PIPERIDYL)OXY]PHENYL] N [(7 AMIDINO 2 NAPHTHYL)METHYL]SULFAMOYL]ACETIC ACID; [N [4 [(1 ACETIMIDOYL 4 PIPERIDYL)OXY]PHENYL] N [(7 AMIDINO 2 NAPTHYL)METHYL]SULFAMOYL]ACETIC ACID; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 0032577589     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00328-8     Document Type: Article
Times cited : (26)

References (16)
  • 2
    • 0018729826 scopus 로고
    • Optimization of conditions for the catalytic effect of the factor IXa-factor VIII complex: Probable role of the complex in the amplification of blood coagulation
    • Elódi S., Varadi K. Optimization of conditions for the catalytic effect of the factor IXa-factor VIII complex: probable role of the complex in the amplification of blood coagulation. Thromb. Res. 15:1979;617-629.
    • (1979) Thromb. Res. , vol.15 , pp. 617-629
    • Elódi, S.1    Varadi, K.2
  • 3
    • 0029111442 scopus 로고
    • DX-9065a, an orally active, specific inhibitor of factor Xa, inhibits thrombosis without affecting bleeding time in rats
    • Hara T., Yokoyama A., Tanabe K., Ishihara H., Iwamoto M. DX-9065a, an orally active, specific inhibitor of factor Xa, inhibits thrombosis without affecting bleeding time in rats. Thromb. Haemost. 74:1995;635-639.
    • (1995) Thromb. Haemost. , vol.74 , pp. 635-639
    • Hara, T.1    Yokoyama, A.2    Tanabe, K.3    Ishihara, H.4    Iwamoto, M.5
  • 4
    • 0030097984 scopus 로고    scopus 로고
    • DX-9065a a novel, synthetic, selective and orally active inhibitor of factor Xa: In vitro and in vivo studies
    • Herbert J.M., Bernat A., Dol F., Herault J.P., Crepon B., Lormeau J.C. DX-9065a a novel, synthetic, selective and orally active inhibitor of factor Xa: in vitro and in vivo studies. J. Pharmacol. Exp. Ther. 276:1996;1030-1038.
    • (1996) J. Pharmacol. Exp. Ther. , vol.276 , pp. 1030-1038
    • Herbert, J.M.1    Bernat, A.2    Dol, F.3    Herault, J.P.4    Crepon, B.5    Lormeau, J.C.6
  • 5
    • 0020964886 scopus 로고
    • Steady state kinetic parameters for the thrombin-catalyzed conversion of human fibrinogen to fibrin
    • Higgins D.L., Lewis S.D., Shafer J.A. Steady state kinetic parameters for the thrombin-catalyzed conversion of human fibrinogen to fibrin. J. Biol. Chem. 258:1983;9276-9282.
    • (1983) J. Biol. Chem. , vol.258 , pp. 9276-9282
    • Higgins, D.L.1    Lewis, S.D.2    Shafer, J.A.3
  • 6
    • 0027932365 scopus 로고
    • Direct thrombin inhibitors in cardiovascular medicine
    • Lefkovits J., Topol E.J. Direct thrombin inhibitors in cardiovascular medicine. Circulation. 90:1994;1522-1536.
    • (1994) Circulation , vol.90 , pp. 1522-1536
    • Lefkovits, J.1    Topol, E.J.2
  • 7
    • 0028561974 scopus 로고
    • The skin bleeding time test as a predictor of brain bleeding time in a rat model
    • MacDonald J.D., Remington B.J., Rodgers G.M. The skin bleeding time test as a predictor of brain bleeding time in a rat model. Thromb. Res. 76:1994;535-540.
    • (1994) Thromb. Res. , vol.76 , pp. 535-540
    • MacDonald, J.D.1    Remington, B.J.2    Rodgers, G.M.3
  • 8
    • 0026556210 scopus 로고
    • Acceleration of recombinant tissue-type plasminogen activator-induced reperfusion and prevention of reocclusion by recombinant antistasin, a selective factor Xa inhibitor, in a canine model of femoral arterial thrombosis
    • Mellott M.J., Holahan M.A., Lynch J.J., Vlasuk G.P., Dunwiddie C.T. Acceleration of recombinant tissue-type plasminogen activator-induced reperfusion and prevention of reocclusion by recombinant antistasin, a selective factor Xa inhibitor, in a canine model of femoral arterial thrombosis. Circ. Res. 70:1992;1152-1160.
    • (1992) Circ. Res. , vol.70 , pp. 1152-1160
    • Mellott, M.J.1    Holahan, M.A.2    Lynch, J.J.3    Vlasuk, G.P.4    Dunwiddie, C.T.5
  • 10
    • 0025801637 scopus 로고
    • The characterization of thrombus development in an improved model of arterio-venous shunt thrombosis in the rat and the effects of recombinant desulphatohirudin (CGP 39393), heparin, and iloprost
    • Peters R.F., Lees C.M., Mitchell K.A., Tweed M.F., Talbot M.D., Wallis R.B. The characterization of thrombus development in an improved model of arterio-venous shunt thrombosis in the rat and the effects of recombinant desulphatohirudin (CGP 39393), heparin, and iloprost. Thromb. Haemost. 65:1991;268-274.
    • (1991) Thromb. Haemost. , vol.65 , pp. 268-274
    • Peters, R.F.1    Lees, C.M.2    Mitchell, K.A.3    Tweed, M.F.4    Talbot, M.D.5    Wallis, R.B.6
  • 11
    • 0018962983 scopus 로고
    • Failure of aspirin at different doses to modify experimental thrombosis in rats
    • Reyers I., Mussoni L., Donati M.B., de Gaetano G. Failure of aspirin at different doses to modify experimental thrombosis in rats. Thromb. Res. 18:1980;669-674.
    • (1980) Thromb. Res. , vol.18 , pp. 669-674
    • Reyers, I.1    Mussoni, L.2    Donati, M.B.3    De Gaetano, G.4
  • 12
    • 0016635205 scopus 로고
    • Activation of human prothrombin by highly purified human factors V and Xa in presence of human antithrombin
    • Rosenberg J.S., Beeler D.L., Rosenberg R.D. Activation of human prothrombin by highly purified human factors V and Xa in presence of human antithrombin. J. Biol. Chem. 250:1975;1607-1617.
    • (1975) J. Biol. Chem. , vol.250 , pp. 1607-1617
    • Rosenberg, J.S.1    Beeler, D.L.2    Rosenberg, R.D.3
  • 14
    • 0031588348 scopus 로고    scopus 로고
    • YM-60828, a novel factor Xa inhibitor: Separation of its antithrombotic effects from its prolongation of bleeding time
    • Sato K., Kawasaki T., Taniuchi Y., Hirayama F., Koshio H., Matsumoto Y. YM-60828, a novel factor Xa inhibitor: separation of its antithrombotic effects from its prolongation of bleeding time. Eur. J. Pharmacol. 339:1997;141-146.
    • (1997) Eur. J. Pharmacol. , vol.339 , pp. 141-146
    • Sato, K.1    Kawasaki, T.2    Taniuchi, Y.3    Hirayama, F.4    Koshio, H.5    Matsumoto, Y.6
  • 15
    • 0031964032 scopus 로고    scopus 로고
    • Antithrombotic effects of YM-60828, a newly synthesized factor Xa inhibitor, in rat thrombosis models and its effects on bleeding time
    • Sato K., Kawasaki T., Hisamichi N., Taniuchi Y., Hirayama F., Koshio H., Matsumoto Y. Antithrombotic effects of YM-60828, a newly synthesized factor Xa inhibitor, in rat thrombosis models and its effects on bleeding time. Br. J. Pharmacol. 123:1998;92-96.
    • (1998) Br. J. Pharmacol. , vol.123 , pp. 92-96
    • Sato, K.1    Kawasaki, T.2    Hisamichi, N.3    Taniuchi, Y.4    Hirayama, F.5    Koshio, H.6    Matsumoto, Y.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.