Site-specific cleavage of G protein-coupled receptor-engaged β-arrestin: Influence of the at1 receptor conformation on scissile site selection

Journal of Biological Chemistry

Volumn 283, Issue 31, 2008, Pages 21612-21620

  Lee, ChangWoo ^a,b   Bhatt, Sumantha ^a   Shukla, Anita ^a   Desnoyer, Russell W ^a   Yadav, Satya P ^a   Kim, Mijin ^b   Jang, Sei Heon ^b   Karnik, Sadashiva S ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b Daegu University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; SUGARS;

ARRESTIN; ARRESTINS; CLEAVAGE SITES; COUPLED RECEPTORS; DIRECT INTERACTIONS; EDMAN DEGRADATION ANALYSES; ENDOCRINE SYSTEMS; ENHANCED GREEN FLUORESCENT PROTEINS; G PROTEINS; ISOFORMS; MASS SPECTROMETRIC ANALYSIS; MEDIATED SIGNALING PATHWAYS; MOUSE HEARTS; PROTEOLYTIC CLEAVAGES; RECEPTOR CONFORMATIONS; SCISSILE SITES; SPLICE VARIANTS; TERMINAL FRAGMENTS; TRANSFECTED CELLS; TRIS PHOSPHATES;

SITE SELECTION;

2 BUTYL 4 CHLORO 1 [[2' (1H TETRAZOL 5 YL) 4 BIPHENYLYL]METHYL] 5 IMIDAZOLECARBOXYLIC ACID; ANGIOTENSIN 1 RECEPTOR; ARGININE; BETA ARRESTIN 1; CALCIUM; G PROTEIN COUPLED RECEPTOR; GREEN FLUORESCENT PROTEIN; INOSITOL 1,4,5 TRISPHOSPHATE; ANGIOTENSIN II; BETA ARRESTIN; RETINA S ANTIGEN;

ANIMAL CELL; ARTICLE; CALCIUM SIGNALING; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; FRAGMENTATION REACTION; GENETIC VARIABILITY; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; RAT; STIMULATION; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CATTLE; CELL STRAIN COS1; CERCOPITHECUS; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION;

BOVINAE;

AMINO ACID SEQUENCE; ANGIOTENSIN II; ANIMALS; ARRESTINS; BINDING SITES; CALCIUM; CATTLE; CERCOPITHECUS AETHIOPS; COS CELLS; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; RATS; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 52049110777     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M803062200     Document Type: Article

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