메뉴 건너뛰기




Volumn 116, Issue 4, 2008, Pages 425-437

Neurotrophic effects of Cerebrolysin in the Mecp2308/Y transgenic model of Rett syndrome

Author keywords

Dendrites; Neurodevelopmental disorders; Neurotrophic peptides

Indexed keywords

CEREBROLYSIN; METHYL CPG BINDING PROTEIN 2;

EID: 51849145627     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-008-0407-x     Document Type: Article
Times cited : (18)

References (66)
  • 1
    • 33645239847 scopus 로고    scopus 로고
    • A 24-week, double-blind, placebo-controlled study of three dosages of Cerebrolysin in patients with mild to moderate Alzheimer's disease
    • doi: 10.1111/j.1468-1331.2006.01222.x
    • Alvarez XA, Cacabelos R, Laredo M, Couceiro V, Sampedro C, Varela M et al (2006) A 24-week, double-blind, placebo-controlled study of three dosages of Cerebrolysin in patients with mild to moderate Alzheimer's disease. Eur J Neurol 13:43-54. doi: 10.1111/j.1468-1331.2006.01222.x
    • (2006) Eur J Neurol , vol.13 , pp. 43-54
    • Alvarez, X.A.1    Cacabelos, R.2    Laredo, M.3    Couceiro, V.4    Sampedro, C.5    Varela, M.6
  • 2
    • 17444440488 scopus 로고    scopus 로고
    • Influence of mutation type and X chromosome inactivation on Rett syndrome phenotypes
    • doi:10.1002/1531-8249(200005)47:5<670::AID-ANA20>3.0.CO;2-F
    • Amir RE, Van den Veyver IB, Schultz R, Malicki DM, Tran CQ, Dahle EJ et al (2000) Influence of mutation type and X chromosome inactivation on Rett syndrome phenotypes. Ann Neurol 47:670-679. doi:10.1002/ 1531-8249(200005)47:5<670::AID-ANA20>3.0.CO;2-F
    • (2000) Ann Neurol , vol.47 , pp. 670-679
    • Amir, R.E.1    Van den Veyver, I.B.2    Schultz, R.3    Malicki, D.M.4    Tran, C.Q.5    Dahle, E.J.6
  • 3
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY (1999) Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet 23:185-188
    • (1999) Nat Genet , vol.23 , pp. 185-188
    • Amir, R.E.1    Van den Veyver, I.B.2    Wan, M.3    Tran, C.Q.4    Francke, U.5    Zoghbi, H.Y.6
  • 4
    • 0028904853 scopus 로고
    • Selective dendritic alterations in the cortex of Rett syndrome
    • doi: 10.1097/00005072-199503000-00006
    • Armstrong D, Dunn JK, Antalffy B, Trivedi R (1995) Selective dendritic alterations in the cortex of Rett syndrome. J Neuropathol Exp Neurol 54:195-201. doi: 10.1097/00005072-199503000-00006
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 195-201
    • Armstrong, D.1    Dunn, J.K.2    Antalffy, B.3    Trivedi, R.4
  • 5
    • 27144534968 scopus 로고    scopus 로고
    • Neuropathology of Rett syndrome
    • Armstrong DD (2005) Neuropathology of Rett syndrome. J Child Neurol 20:747-753
    • (2005) J Child Neurol , vol.20 , pp. 747-753
    • Armstrong, D.D.1
  • 6
    • 0031761177 scopus 로고    scopus 로고
    • Decreased dendritic branching in frontal, motor and limbic cortex in Rett syndrome compared with trisomy 21
    • doi: 10.1097/00005072-199811000-00003
    • Armstrong DD, Dunn K, Antalffy B (1998) Decreased dendritic branching in frontal, motor and limbic cortex in Rett syndrome compared with trisomy 21. J Neuropathol Exp Neurol 57:1013-1017. doi: 10.1097/ 00005072-199811000-00003
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 1013-1017
    • Armstrong, D.D.1    Dunn, K.2    Antalffy, B.3
  • 7
    • 0030639079 scopus 로고    scopus 로고
    • Morphological study of neocortical areas in Rett syndrome
    • doi: 10.1007/s004010050582
    • Belichenko PV, Hagberg B, Dahlstrom A (1997) Morphological study of neocortical areas in Rett syndrome. Acta Neuropathol 93:50-61. doi: 10.1007/s004010050582
    • (1997) Acta Neuropathol , vol.93 , pp. 50-61
    • Belichenko, P.V.1    Hagberg, B.2    Dahlstrom, A.3
  • 8
    • 0034701999 scopus 로고    scopus 로고
    • MECP2 mutations account for most cases of typical forms of Rett syndrome
    • doi: 10.1093/hmg/9.9.1377
    • Bienvenu T, Carrie A, de Roux N, Vinet MC, Jonveaux P, Couvert P et al (2000) MECP2 mutations account for most cases of typical forms of Rett syndrome. Hum Mol Genet 9:1377-1384. doi: 10.1093/hmg/9.9.1377
    • (2000) Hum Mol Genet , vol.9 , pp. 1377-1384
    • Bienvenu, T.1    Carrie, A.2    de Roux, N.3    Vinet, M.C.4    Jonveaux, P.5    Couvert, P.6
  • 9
    • 0035093830 scopus 로고    scopus 로고
    • Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
    • doi: 10.1038/85906
    • Chen RZ, Akbarian S, Tudor M, Jaenisch R (2001) Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice. Nat Genet 27:327-331. doi: 10.1038/85906
    • (2001) Nat Genet , vol.27 , pp. 327-331
    • Chen, R.Z.1    Akbarian, S.2    Tudor, M.3    Jaenisch, R.4
  • 10
    • 0030986183 scopus 로고    scopus 로고
    • Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits
    • doi: 10.1073/pnas.94.10.5401
    • Comery TA, Harris JB, Willems PJ, Oostra BA, Irwin SA, Weiler IJ et al (1997) Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits. Proc Natl Acad Sci USA 94:5401-5404. doi: 10.1073/ pnas.94.10.5401
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 5401-5404
    • Comery, T.A.1    Harris, J.B.2    Willems, P.J.3    Oostra, B.A.4    Irwin, S.A.5    Weiler, I.J.6
  • 12
    • 0036460460 scopus 로고    scopus 로고
    • Dopamine transporter knock-out mice are hypersensitive to 3-nitropropionic acid-induced striatal damage
    • doi: 10.1046/j.1460-9568.2002.02047.x
    • Fernagut PO, Diguet E, Jaber M, Bioulac B, Tison F (2002) Dopamine transporter knock-out mice are hypersensitive to 3-nitropropionic acid-induced striatal damage. Eur J NeuroSci 15:2053-2056. doi: 10.1046/ j.1460-9568.2002.02047.x
    • (2002) Eur J NeuroSci , vol.15 , pp. 2053-2056
    • Fernagut, P.O.1    Diguet, E.2    Jaber, M.3    Bioulac, B.4    Tison, F.5
  • 13
    • 7044270767 scopus 로고    scopus 로고
    • Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein
    • doi: 10.1523/JNEUROSCI.3080-04.2004
    • Fleming SM, Salcedo J, Fernagut PO, Rockenstein E, Masliah E, Levine MS et al (2004) Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein. J Neurosci 24:9434-9440. doi: 10.1523/JNEUROSCI.3080-04.2004
    • (2004) J Neurosci , vol.24 , pp. 9434-9440
    • Fleming, S.M.1    Salcedo, J.2    Fernagut, P.O.3    Rockenstein, E.4    Masliah, E.5    Levine, M.S.6
  • 14
    • 17044458021 scopus 로고    scopus 로고
    • Nerve growth factor and nootropic drug Cerebrolysin but not fibroblast growth factor can reduce spatial memory impairment elicited by fimbria-fornix transection: Short-term study
    • doi: 10.1016/0304-3940(95)12240-0
    • Francis-Turner L, Valouskova V (1996) Nerve growth factor and nootropic drug Cerebrolysin but not fibroblast growth factor can reduce spatial memory impairment elicited by fimbria-fornix transection: Short-term study. Neurosci Lett 202:1-4. doi: 10.1016/0304-3940(95)12240-0
    • (1996) Neurosci Lett , vol.202 , pp. 1-4
    • Francis-Turner, L.1    Valouskova, V.2
  • 15
    • 0037423186 scopus 로고    scopus 로고
    • The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation
    • doi: 10.1074/jbc.M210256200
    • Fuks F, Hurd PJ, Wolf D, Nan X, Bird AP, Kouzarides T (2003) The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation. J Biol Chem 278:4035-4040. doi: 10.1074/jbc.M210256200
    • (2003) J Biol Chem , vol.278 , pp. 4035-4040
    • Fuks, F.1    Hurd, P.J.2    Wolf, D.3    Nan, X.4    Bird, A.P.5    Kouzarides, T.6
  • 16
    • 0035197321 scopus 로고    scopus 로고
    • Cerebrolysin therapy in Rett syndrome: Clinical and EEG mapping study
    • doi: 10.1016/S0387-7604(01)00349-7
    • Gorbachevskaya N, Bashina V, Gratchev V, Iznak A (2001) Cerebrolysin therapy in Rett syndrome: Clinical and EEG mapping study. Brain Dev 23(Suppl. 1):S90-S93. doi: 10.1016/S0387-7604(01)00349-7
    • (2001) Brain Dev , vol.23 , Issue.SUPPL. 1
    • Gorbachevskaya, N.1    Bashina, V.2    Gratchev, V.3    Iznak, A.4
  • 17
    • 0032847667 scopus 로고    scopus 로고
    • Patterning events and specification signals in the developing hippocampus
    • doi: 10.1093/cercor/9.6.551
    • Grove EA, Tole S (1999) Patterning events and specification signals in the developing hippocampus. Cereb Cortex 9:551-561. doi: 10.1093/cercor/ 9.6.551
    • (1999) Cereb Cortex , vol.9 , pp. 551-561
    • Grove, E.A.1    Tole, S.2
  • 18
    • 0033061554 scopus 로고    scopus 로고
    • Early postnatal treatment with peptide preparations influences spatial navigation of young and adult rats
    • doi: 10.1016/S0166-4328(98)00127-2
    • Gschanes A, Windisch M (1999) Early postnatal treatment with peptide preparations influences spatial navigation of young and adult rats. Behav Brain Res 100:161-166. doi: 10.1016/S0166-4328(98)00127-2
    • (1999) Behav Brain Res , vol.100 , pp. 161-166
    • Gschanes, A.1    Windisch, M.2
  • 19
    • 0035094767 scopus 로고    scopus 로고
    • A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
    • doi: 10.1038/85899
    • Guy J, Hendrich B, Holmes M, Martin JE, Bird A (2001) A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat Genet 27:322-326. doi: 10.1038/85899
    • (2001) Nat Genet , vol.27 , pp. 322-326
    • Guy, J.1    Hendrich, B.2    Holmes, M.3    Martin, J.E.4    Bird, A.5
  • 20
    • 0036270792 scopus 로고    scopus 로고
    • Clinical manifestations and stages of Rett syndrome
    • doi: 10.1002/mrdd.10020
    • Hagberg B (2002) Clinical manifestations and stages of Rett syndrome. Ment Retard Dev Disabil Res Rev 8:61-65. doi: 10.1002/mrdd.10020
    • (2002) Ment Retard Dev Disabil Res Rev , vol.8 , pp. 61-65
    • Hagberg, B.1
  • 21
    • 11244290255 scopus 로고    scopus 로고
    • Reinnervation of the rat musculocutaneous nerve stump after its direct reconnection with the C5 spinal cord segment by the nerve graft following avulsion of the ventral spinal roots: A comparison of intrathecal administration of brain-derived neurotrophic factor and Cerebrolysin
    • doi: 10.1007/s00221-004-1969-z
    • Haninec P, Dubovy P, Samal F, Houstava L, Stejskal L (2004) Reinnervation of the rat musculocutaneous nerve stump after its direct reconnection with the C5 spinal cord segment by the nerve graft following avulsion of the ventral spinal roots: A comparison of intrathecal administration of brain-derived neurotrophic factor and Cerebrolysin. Exp Brain Res 159:425-432. doi: 10.1007/s00221-004-1969-z
    • (2004) Exp Brain Res , vol.159 , pp. 425-432
    • Haninec, P.1    Dubovy, P.2    Samal, F.3    Houstava, L.4    Stejskal, L.5
  • 22
    • 0038203257 scopus 로고    scopus 로고
    • Rescue of rat spinal motoneurons from avulsion-induced cell death by intrathecal administration of IGF-I and Cerebrolysin
    • doi: 10.1016/S0940-9602(03)80030-4
    • Haninec P, Houst'ava L, Stejskal L, Dubovy P (2003) Rescue of rat spinal motoneurons from avulsion-induced cell death by intrathecal administration of IGF-I and Cerebrolysin. Ann Anat 185:233-238. doi: 10.1016/S0940-9602(03)80030-4
    • (2003) Ann Anat , vol.185 , pp. 233-238
    • Haninec, P.1    Houst'ava, L.2    Stejskal, L.3    Dubovy, P.4
  • 23
    • 0035033947 scopus 로고    scopus 로고
    • Effects of Cerebrolysin on the outgrowth and protection of processes of cultured brain neurons
    • doi: 10.1007/s007020170058
    • Hartbauer M, Hutter-Paie B, Windisch M (2001) Effects of Cerebrolysin on the outgrowth and protection of processes of cultured brain neurons. J Neural Transm 108:581-592. doi: 10.1007/s007020170058
    • (2001) J Neural Transm , vol.108 , pp. 581-592
    • Hartbauer, M.1    Hutter-Paie, B.2    Windisch, M.3
  • 24
    • 0034895512 scopus 로고    scopus 로고
    • Antiapoptotic effects of the peptidergic drug cerebrolysin on primary cultures of embryonic chick cortical neurons
    • doi: 10.1007/s007020170067
    • Hartbauer M, Hutter-Paier B, Skofitsch G, Windisch M (2001) Antiapoptotic effects of the peptidergic drug cerebrolysin on primary cultures of embryonic chick cortical neurons. J Neural Transm 108:459-473. doi: 10.1007/s007020170067
    • (2001) J Neural Transm , vol.108 , pp. 459-473
    • Hartbauer, M.1    Hutter-Paier, B.2    Skofitsch, G.3    Windisch, M.4
  • 25
    • 0029815427 scopus 로고    scopus 로고
    • Cerebrolysin protects neurons from ischemia-induced loss of microtubule-associated protein 2
    • Hutter-Paier B, Fruhwirth M, Grygar E, Windisch M (1996) Cerebrolysin protects neurons from ischemia-induced loss of microtubule-associated protein 2. J Neural Transm Suppl 47:276
    • (1996) J Neural Transm Suppl , vol.47 , pp. 276
    • Hutter-Paier, B.1    Fruhwirth, M.2    Grygar, E.3    Windisch, M.4
  • 26
    • 0031596281 scopus 로고    scopus 로고
    • Cerebrolysin protects isolated cortical neurons from neurodegeneration after brief histotoxic hypoxia
    • Hutter-Paier B, Steiner E, Windisch M (1998) Cerebrolysin protects isolated cortical neurons from neurodegeneration after brief histotoxic hypoxia. J Neural Transm Suppl 53:351-361
    • (1998) J Neural Transm Suppl , vol.53 , pp. 351-361
    • Hutter-Paier, B.1    Steiner, E.2    Windisch, M.3
  • 27
    • 14244261010 scopus 로고    scopus 로고
    • 3, 4-dihydroxyphenylalanine reverses the motor deficits in Pitx3-deficient aphakia mice: Behavioral characterization of a novel genetic model of Parkinson's disease
    • doi: 10.1523/JNEUROSCI.3718-04.2005
    • Hwang DY, Fleming SM, Ardayfio P, Moran-Gates T, Kim H, Tarazi FI et al (2005) 3, 4-dihydroxyphenylalanine reverses the motor deficits in Pitx3-deficient aphakia mice: Behavioral characterization of a novel genetic model of Parkinson's disease. J Neurosci 25:2132-2137. doi: 10.1523/JNEUROSCI.3718-04.2005
    • (2005) J Neurosci , vol.25 , pp. 2132-2137
    • Hwang, D.Y.1    Fleming, S.M.2    Ardayfio, P.3    Moran-Gates, T.4    Kim, H.5    Tarazi, F.I.6
  • 28
    • 0038182387 scopus 로고    scopus 로고
    • Rett syndrome - An update
    • doi: 10.1007/s00702-003-0822-z
    • Jellinger KA (2003) Rett syndrome - an update. J Neural Transm 110:681-701. doi: 10.1007/s00702-003-0822-z
    • (2003) J Neural Transm , vol.110 , pp. 681-701
    • Jellinger, K.A.1
  • 29
    • 0029065169 scopus 로고
    • Abnormal expression of microtubule-associated protein 2 (MAP-2) in neocortex in Rett syndrome
    • Kaufmann WE, Naidu S, Budden S (1995) Abnormal expression of microtubule-associated protein 2 (MAP-2) in neocortex in Rett syndrome. Neuropediatrics 26:109-113
    • (1995) Neuropediatrics , vol.26 , pp. 109-113
    • Kaufmann, W.E.1    Naidu, S.2    Budden, S.3
  • 30
    • 0031455739 scopus 로고    scopus 로고
    • Abnormalities in neuronal maturation in Rett syndrome neocortex: Preliminary molecular correlates
    • Kaufmann WE, Taylor CV, Hohmann CF, Sanwal IB, Naidu S (1997) Abnormalities in neuronal maturation in Rett syndrome neocortex: preliminary molecular correlates. Eur Child Adolesc Psychiatry 6(Suppl. 1):75-77
    • (1997) Eur Child Adolesc Psychiatry , vol.6 , Issue.SUPPL. 1 , pp. 75-77
    • Kaufmann, W.E.1    Taylor, C.V.2    Hohmann, C.F.3    Sanwal, I.B.4    Naidu, S.5
  • 31
    • 0029001282 scopus 로고
    • Early clinical signs in the Rett disorder
    • Kerr AM (1995) Early clinical signs in the Rett disorder. Neuropediatrics 26:67-71
    • (1995) Neuropediatrics , vol.26 , pp. 67-71
    • Kerr, A.M.1
  • 32
    • 34548205779 scopus 로고    scopus 로고
    • Escalating dose-multiple binge methamphetamine exposure results in degeneration of the neocortex and limbic system in the rat
    • doi: 10.1016/j.expneurol.2007.05.023
    • Kuczenski R, Everall IP, Crews L, Adame A, Grant I, Masliah E (2007) Escalating dose-multiple binge methamphetamine exposure results in degeneration of the neocortex and limbic system in the rat. Exp Neurol 207:42-51. doi: 10.1016/j.expneurol.2007.05.023
    • (2007) Exp Neurol , vol.207 , pp. 42-51
    • Kuczenski, R.1    Everall, I.P.2    Crews, L.3    Adame, A.4    Grant, I.5    Masliah, E.6
  • 33
    • 0026747761 scopus 로고
    • Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA
    • doi: 10.1016/0092-8674(92)90610-O
    • Lewis JD, Meehan RR, Henzel WJ, Maurer-Fogy I, Jeppesen P, Klein F et al (1992) Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA. Cell 69:905-914. doi: 10.1016/0092-8674(92)90610-O
    • (1992) Cell , vol.69 , pp. 905-914
    • Lewis, J.D.1    Meehan, R.R.2    Henzel, W.J.3    Maurer-Fogy, I.4    Jeppesen, P.5    Klein, F.6
  • 34
    • 0032915920 scopus 로고    scopus 로고
    • In vitro synaptotrophic effects of Cerebrolysin in NT2 N cells
    • doi: 10.1007/s004010051012
    • Mallory M, Honer W, Hsu L, Johnson R, Rockenstein E, Masliah E (1999) In vitro synaptotrophic effects of Cerebrolysin in NT2 N cells. Acta Neuropathol 97:437-446. doi: 10.1007/s004010051012
    • (1999) Acta Neuropathol , vol.97 , pp. 437-446
    • Mallory, M.1    Honer, W.2    Hsu, L.3    Johnson, R.4    Rockenstein, E.5    Masliah, E.6
  • 35
    • 0032932837 scopus 로고    scopus 로고
    • Cerebrolysin ameliorates performance deficits, and neuronal damage in apolipoprotein E-deficient mice
    • doi: 10.1016/S0091-3057(98)00144-0
    • Masliah E, Armasolo F, Veinbergs I, Mallory M, Samuel W (1999) Cerebrolysin ameliorates performance deficits, and neuronal damage in apolipoprotein E-deficient mice. Pharmacol Biochem Behav 62:239-245. doi: 10.1016/S0091-3057(98)00144-0
    • (1999) Pharmacol Biochem Behav , vol.62 , pp. 239-245
    • Masliah, E.1    Armasolo, F.2    Veinbergs, I.3    Mallory, M.4    Samuel, W.5
  • 36
    • 0343052652 scopus 로고    scopus 로고
    • Pole test is a useful method for evaluating the mouse movement disorder caused by striatal dopamine depletion
    • doi: 10.1016/S0165-0270(96)02211-X
    • Matsuura K, Kabuto H, Makino H, Ogawa N (1997) Pole test is a useful method for evaluating the mouse movement disorder caused by striatal dopamine depletion. J Neurosci Methods 73:45-48. doi: 10.1016/ S0165-0270(96)02211-X
    • (1997) J Neurosci Methods , vol.73 , pp. 45-48
    • Matsuura, K.1    Kabuto, H.2    Makino, H.3    Ogawa, N.4
  • 37
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • doi: 10.1093/nar/16.3.1215
    • Miller S, Dykes D, Polesky H (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:1215. doi: 10.1093/nar/16.3.1215
    • (1988) Nucleic Acids Res , vol.16 , pp. 1215
    • Miller, S.1    Dykes, D.2    Polesky, H.3
  • 38
    • 12744261491 scopus 로고    scopus 로고
    • Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome
    • doi: 10.1093/hmg/ddi016
    • Moretti P, Bouwknecht JA, Teague R, Paylor R, Zoghbi HY (2005) Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome. Hum Mol Genet 14:205-220. doi: 10.1093/hmg/ddi016
    • (2005) Hum Mol Genet , vol.14 , pp. 205-220
    • Moretti, P.1    Bouwknecht, J.A.2    Teague, R.3    Paylor, R.4    Zoghbi, H.Y.5
  • 39
    • 30644479042 scopus 로고    scopus 로고
    • Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome
    • doi: 10.1523/JNEUROSCI.2623-05.2006
    • Moretti P, Levenson JM, Battaglia F, Atkinson R, Teague R, Antalffy B et al (2006) Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome. J Neurosci 26:319-327. doi: 10.1523/ JNEUROSCI.2623-05.2006
    • (2006) J Neurosci , vol.26 , pp. 319-327
    • Moretti, P.1    Levenson, J.M.2    Battaglia, F.3    Atkinson, R.4    Teague, R.5    Antalffy, B.6
  • 40
    • 39149133958 scopus 로고    scopus 로고
    • A pilot study to evaluate the effects of Cerebrolysin on cognition and qEEG in vascular dementia: Cognitive improvement correlates with qEEG acceleration
    • doi: 10.1016/j.jns.2007.10.016
    • Muresanu DF, Alvarez XA, Moessler H, Buia M, Stan A, Pintea D et al (2008) A pilot study to evaluate the effects of Cerebrolysin on cognition and qEEG in vascular dementia: Cognitive improvement correlates with qEEG acceleration. J Neurol Sci 267:112-119. doi: 10.1016/j.jns.2007.10.016
    • (2008) J Neurol Sci , vol.267 , pp. 112-119
    • Muresanu, D.F.1    Alvarez, X.A.2    Moessler, H.3    Buia, M.4    Stan, A.5    Pintea, D.6
  • 41
    • 0342437491 scopus 로고    scopus 로고
    • MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin
    • doi: 10.1016/S0092-8674(00)81887-5
    • Nan X, Campoy FJ, Bird A (1997) MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin. Cell 88:471-481. doi: 10.1016/S0092-8674(00)81887-5
    • (1997) Cell , vol.88 , pp. 471-481
    • Nan, X.1    Campoy, F.J.2    Bird, A.3
  • 42
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • doi: 10.1038/30764
    • Nan X, Ng HH, Johnson CA, Laherty CD, Turner BM, Eisenman RN et al (1998) Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393:386-389. doi: 10.1038/30764
    • (1998) Nature , vol.393 , pp. 386-389
    • Nan, X.1    Ng, H.H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6
  • 43
    • 0029655782 scopus 로고    scopus 로고
    • DNA methylation specifies chromosomal localization of MeCP2
    • Nan X, Tate P, Li E, Bird A (1996) DNA methylation specifies chromosomal localization of MeCP2. Mol Cell Biol 16:414-421
    • (1996) Mol Cell Biol , vol.16 , pp. 414-421
    • Nan, X.1    Tate, P.2    Li, E.3    Bird, A.4
  • 44
    • 0021929479 scopus 로고
    • Rett syndrome - An early catecholamine and indolamine deficient disorder?
    • Nomura Y, Segawa M, Higurashi M (1985) Rett syndrome - an early catecholamine and indolamine deficient disorder? Brain Dev 7:334-341
    • (1985) Brain Dev , vol.7 , pp. 334-341
    • Nomura, Y.1    Segawa, M.2    Higurashi, M.3
  • 46
    • 0023100407 scopus 로고
    • MPTP-induced parkinsonian model in mice: Biochemistry, pharmacology and behavior
    • doi: 10.1159/000116351
    • Ogawa N, Mizukawa K, Hirose Y, Kajita S, Ohara S, Watanabe Y (1987) MPTP-induced parkinsonian model in mice: Biochemistry, pharmacology and behavior. Eur Neurol 26(Suppl. 1):16-23. doi: 10.1159/000116351
    • (1987) Eur Neurol , vol.26 , Issue.SUPPL. 1 , pp. 16-23
    • Ogawa, N.1    Mizukawa, K.2    Hirose, Y.3    Kajita, S.4    Ohara, S.5    Watanabe, Y.6
  • 47
    • 0023554777 scopus 로고
    • Rett syndrome: Discrimination of typical and variant forms
    • Percy AK, Zoghbi HY, Glaze DG (1987) Rett syndrome: Discrimination of typical and variant forms. Brain Dev 9:458-461
    • (1987) Brain Dev , vol.9 , pp. 458-461
    • Percy, A.K.1    Zoghbi, H.Y.2    Glaze, D.G.3
  • 48
    • 0001516546 scopus 로고
    • Some results of research into the development of the neuronal structure of the cortical ends of the analyzers in man
    • doi: 10.1002/cne.901170206
    • Poliakov GI (1961) Some results of research into the development of the neuronal structure of the cortical ends of the analyzers in man. J Comp Neurol 117:197-212. doi: 10.1002/cne.901170206
    • (1961) J Comp Neurol , vol.117 , pp. 197-212
    • Poliakov, G.I.1
  • 49
    • 0032774942 scopus 로고    scopus 로고
    • Two peptidergic drugs increase the synaptophysin immunoreactivity in brains of 24-month-old rats
    • doi: 10.1023/A:1003752208971
    • Reinprecht I, Gschanes A, Windisch M, Fachbach G (1999) Two peptidergic drugs increase the synaptophysin immunoreactivity in brains of 24-month-old rats. Histochem J 31:395-401. doi: 10.1023/A:1003752208971
    • (1999) Histochem J , vol.31 , pp. 395-401
    • Reinprecht, I.1    Gschanes, A.2    Windisch, M.3    Fachbach, G.4
  • 50
    • 0345059236 scopus 로고    scopus 로고
    • The neuroprotective effects of Cerebrolysin trade mark in a transgenic model of Alzheimer's disease are associated with improved behavioral performance
    • doi: 10.1007/s00702-003-0025-7
    • Rockenstein E, Adame A, Mante M, Moessler H, Windisch M, Masliah E (2003) The neuroprotective effects of Cerebrolysin trade mark in a transgenic model of Alzheimer's disease are associated with improved behavioral performance. J Neural Transm 110:1313-1327. doi: 10.1007/ s00702-003-0025-7
    • (2003) J Neural Transm , vol.110 , pp. 1313-1327
    • Rockenstein, E.1    Adame, A.2    Mante, M.3    Moessler, H.4    Windisch, M.5    Masliah, E.6
  • 52
    • 33947389569 scopus 로고    scopus 로고
    • Effects of Cerebrolysintrade mark on neurogenesis in an APP transgenic model of Alzheimer's disease
    • doi: 10.1007/s00401-006-0166-5
    • Rockenstein E, Mante M, Adame A, Crews L, Moessler H, Masliah E (2007) Effects of Cerebrolysintrade mark on neurogenesis in an APP transgenic model of Alzheimer's disease. Acta Neuropathol 113:265-275. doi: 10.1007/ s00401-006-0166-5
    • (2007) Acta Neuropathol , vol.113 , pp. 265-275
    • Rockenstein, E.1    Mante, M.2    Adame, A.3    Crews, L.4    Moessler, H.5    Masliah, E.6
  • 53
    • 33646364811 scopus 로고    scopus 로고
    • Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease
    • doi: 10.1002/jnr.20818
    • Rockenstein E, Torrance M, Mante M, Adame A, Paulino A, Rose JB et al (2006) Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease. J Neurosci Res 83:1252-1261. doi: 10.1002/jnr.20818
    • (2006) J Neurosci Res , vol.83 , pp. 1252-1261
    • Rockenstein, E.1    Torrance, M.2    Mante, M.3    Adame, A.4    Paulino, A.5    Rose, J.B.6
  • 54
    • 33646364811 scopus 로고    scopus 로고
    • Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease
    • Rockenstein E, Torrance M, Mante M, Adame A, Paulino A, Rose JB, Crews L, Moessler H, Masliah E (2006) Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease. J Neurosci Res 83(7):1252-61.
    • (2006) J Neurosci Res , vol.83 , Issue.7 , pp. 1252-1261
    • Rockenstein, E.1    Torrance, M.2    Mante, M.3    Adame, A.4    Paulino, A.5    Rose, J.B.6    Crews, L.7    Moessler, H.8    Masliah, E.9
  • 55
    • 0033747106 scopus 로고    scopus 로고
    • Neurotrophic effects of FPF-1070 (Cerebrolysin) on cultured neurons from chicken embryo dorsal root ganglia, ciliary ganglia, and sympathetic trunks
    • doi: 10.1007/s007020070015
    • Satou T, Itoh T, Tamai Y, Ohde H, Anderson AJ, Hashimoto S (2000) Neurotrophic effects of FPF-1070 (Cerebrolysin) on cultured neurons from chicken embryo dorsal root ganglia, ciliary ganglia, and sympathetic trunks. J Neural Transm 107:1253-1262. doi: 10.1007/s007020070015
    • (2000) J Neural Transm , vol.107 , pp. 1253-1262
    • Satou, T.1    Itoh, T.2    Tamai, Y.3    Ohde, H.4    Anderson, A.J.5    Hashimoto, S.6
  • 56
    • 0037130455 scopus 로고    scopus 로고
    • Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3
    • doi: 10.1016/S0896-6273(02)00768-7
    • Shahbazian M, Young J, Yuva-Paylor L, Spencer C, Antalffy B, Noebels J et al (2002) Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3. Neuron 35:243-254. doi: 10.1016/S0896-6273(02)00768-7
    • (2002) Neuron , vol.35 , pp. 243-254
    • Shahbazian, M.1    Young, J.2    Yuva-Paylor, L.3    Spencer, C.4    Antalffy, B.5    Noebels, J.6
  • 57
    • 0036917867 scopus 로고    scopus 로고
    • Rett syndrome and MeCP2: Linking epigenetics and neuronal function
    • doi: 10.1086/345360
    • Shahbazian MD, Zoghbi HY (2002) Rett syndrome and MeCP2: Linking epigenetics and neuronal function. Am J Hum Genet 71:1259-1272. doi: 10.1086/345360
    • (2002) Am J Hum Genet , vol.71 , pp. 1259-1272
    • Shahbazian, M.D.1    Zoghbi, H.Y.2
  • 58
    • 34247862140 scopus 로고    scopus 로고
    • Behavioral and anatomical abnormalities in Mecp2 mutant mice: A model for Rett syndrome
    • doi: 10.1016/j.neuroscience.2007.02.009
    • Stearns NA, Schaevitz LR, Bowling H, Nag N, Berger UV, Berger-Sweeney J (2007) Behavioral and anatomical abnormalities in Mecp2 mutant mice: A model for Rett syndrome. Neuroscience 146:907-921. doi: 10.1016/ j.neuroscience.2007.02.009
    • (2007) Neuroscience , vol.146 , pp. 907-921
    • Stearns, N.A.1    Schaevitz, L.R.2    Bowling, H.3    Nag, N.4    Berger, U.V.5    Berger-Sweeney, J.6
  • 60
    • 0031469495 scopus 로고    scopus 로고
    • Early specification and autonomous development of cortical fields in the mouse hippocampus
    • Tole S, Christian C, Grove EA (1997) Early specification and autonomous development of cortical fields in the mouse hippocampus. Development 124:4959-4970
    • (1997) Development , vol.124 , pp. 4959-4970
    • Tole, S.1    Christian, C.2    Grove, E.A.3
  • 62
    • 0033365401 scopus 로고    scopus 로고
    • Rett syndrome and beyond: Recurrent spontaneous and familial MECP2 mutations at CpG hotspots
    • doi: 10.1086/302690
    • Wan M, Lee SS, Zhang X, Houwink-Manville I, Song HR, Amir RE et al (1999) Rett syndrome and beyond: Recurrent spontaneous and familial MECP2 mutations at CpG hotspots. Am J Hum Genet 65:1520-1529. doi: 10.1086/302690
    • (1999) Am J Hum Genet , vol.65 , pp. 1520-1529
    • Wan, M.1    Lee, S.S.2    Zhang, X.3    Houwink-Manville, I.4    Song, H.R.5    Amir, R.E.6
  • 63
    • 34247492801 scopus 로고    scopus 로고
    • Meta-analysis: The efficacy of nootropic agent Cerebrolysin in the treatment of Alzheimer's disease
    • doi: 10.1007/s00702-007-0630-y
    • Wei ZH, He QB, Wang H, Su BH, Chen HZ (2007) Meta-analysis: The efficacy of nootropic agent Cerebrolysin in the treatment of Alzheimer's disease. J Neural Transm 114:629-634. doi: 10.1007/s00702-007-0630-y
    • (2007) J Neural Transm , vol.114 , pp. 629-634
    • Wei, Z.H.1    He, Q.B.2    Wang, H.3    Su, B.H.4    Chen, H.Z.5
  • 64
    • 0034090892 scopus 로고    scopus 로고
    • Two peptidergic drugs increase the synaptophysin immunoreactivity in brains of 6-week-old rats
    • doi: 10.1023/A:1004053809591
    • Windholz E, Gschanes A, Windisch M, Fachbach G (2000) Two peptidergic drugs increase the synaptophysin immunoreactivity in brains of 6-week-old rats. Histochem J 32:79-84. doi: 10.1023/A:1004053809591
    • (2000) Histochem J , vol.32 , pp. 79-84
    • Windholz, E.1    Gschanes, A.2    Windisch, M.3    Fachbach, G.4
  • 65
    • 0033624429 scopus 로고    scopus 로고
    • A brain derived peptide preparation reduces the translation dependent loss of a cytoskeletal protein in primary cultured chicken neurons
    • Wronski R, Kronawetter S, Hutter-Paier B, Crailsheim K, Windisch M (2000) A brain derived peptide preparation reduces the translation dependent loss of a cytoskeletal protein in primary cultured chicken neurons. J Neural Transm Suppl 59:263-272
    • (2000) J Neural Transm Suppl , vol.59 , pp. 263-272
    • Wronski, R.1    Kronawetter, S.2    Hutter-Paier, B.3    Crailsheim, K.4    Windisch, M.5
  • 66
    • 1542344372 scopus 로고    scopus 로고
    • X-chromosome inactivation patterns are unbalanced and affect the phenotypic outcome in a mouse model of rett syndrome
    • doi: 10.1086/382228
    • Young JI, Zoghbi HY (2004) X-chromosome inactivation patterns are unbalanced and affect the phenotypic outcome in a mouse model of rett syndrome. Am J Hum Genet 74:511-520. doi: 10.1086/382228
    • (2004) Am J Hum Genet , vol.74 , pp. 511-520
    • Young, J.I.1    Zoghbi, H.Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.