Nerve growth factor and nootropic drug Cerebrolysin but not fibroblast growth factor can reduce spatial memory impairment elicited by fimbria-fornix transection: Short-term study

Neuroscience Letters

Volumn 202, Issue 3, 1996, Pages 193-196

  Francis Turner, Liliana ^a,b   Valouŝková, Vêra ^a  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

^b CENTRO INTERNACIONAL DE RESTAURACIÓN NEUROLÓGICA CIREN   (Cuba)

Author keywords

Basic fibroblast growth factor; Central nervous system regeneration; Cerebrolysin; Fimbria fornix lesion; Nerve growth factor; Retrograde and anterograde amnesia; Spatial memory

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CEREBROLYSIN; NERVE GROWTH FACTOR; NOOTROPIC AGENT;

ANIMAL EXPERIMENT; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; LEARNING; MALE; MAZE TEST; NONHUMAN; PRIORITY JOURNAL; RAT; SPATIAL MEMORY;

EID: 17044458021     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(95)12240-0     Document Type: Article

References (23)

1. Akai, F., Hiruma S., Sato, T., Iwamoto N., Fujimoto, M., Ioku, M. and Hashimoto, S., Neurotrophic factor-like effect of FPF1070 on septal cholinergic neurons after transection of fimbria-fornix in the rat brain, Histol. Histopathol., 7 (1992) 213-221.
2. Bartus, R.T., Dean, R.L., Beer, B. and Lippa, A.S., The cholinergic hypothesis of geriatric memory dysfunction, Science, 217 (1982) 408-417.
3. Fischer, W., Wictorin K., Björklund A., Williams, L.R., Varon, S. and Gage, F.H., Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor, Nature, 329 (1987) 65-68.
4. Gage, F.H., Björklund, A., Stenevi, U. and Dunnett, S., Functional correlates of compensatory collateral sprouting by aminergic and cholinergic afferent in the hippocampal formation, Brain. Res., 268 (1983) 39-47.
5. Gnahn, M., Hefti, F., Heumann, R., Schwab, M. and Thoenen, M., NGF-mediated increase of choline acetyltransferase (ChAT) in the neonatal forebrain: evidence for a physiological role of NGF in the brain, Dev. Brain Res., 9 (1983) 45-52.
6. Grothe, C., Otto, D. and Unsicker, K., Basic fibroblast growth factor promotes in vitro survival and cholinergic development of rat septal neurons: comparison with the effects of nerve growth factor, Neuroscience, 31 (1989) 649-661.
7. Gschanes, A. and Valoušková, V., An effect of NGF, b-FGF and nootropic drug Cerebrolysin on spatial memory and on motor activity of rats: short-and long-term study, Exp. Neurol., (1995) submitted.
8. Haynes, L.W., Fibroblast (heparin-binding) growing factors in neural development and repair, Mol. Neurobiol., 2 (1988) 263-289.
9. Hefti, F., Nerve growth factor promotes survival of septal cholinergic neurons after fimbria transection, J. Neurosci., 6 (1986) 2155-2162.
10. Hefti, F., Dravid, A. and Hartika, J., Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with partial septohippocampal lesions, Brain Res., 293 (1984) 305-311.
11. Kofler, B., Erhart, C., Erhart, P. and Harrer, G.A., Multidimensional approach in testing nootropic drug effects (Cerebrolysin), Arch. Gerontol. Geriatr., 10 (1990) 129-140.
12. Korsching, S., Auburger, G., Heumann, R., Scatt, J. and Thoenen, M., Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation, EMBO. J., 4 (1985) 1389-1393.
13. Liu, Z., Francis-Turner, L. and Bures, J., Impairment of place navigation of rats in the Morris water maze by intermittent light is inversely related to the duration of the flash, Neurosci. Lett., 180 (1994) 59-62.
14. McKinney, M., Colyle, J.T. and Hedreen, J.C., Topographic analysis of the innervation of the rat neocortex and hippocampus by the basal forebrain cholinergic system, J. Comp. Neurol., 217 (1983) 103-121.
15. Mobley, W.V., Rutkowski, J.L., Jennekon, G.I., Buchanan, K. and Jannson, M.V., Choline acetyltransferase in striatum of neonatal rats increased by nerve growth factor, Science, 229 (1985) 284-287.
16. Osamu, M., Toshifumi, I., Mutsuo, F., Masaki, T., Hideki, M., Seigo, N. and Osamu, H., Exogenous basic fibroblast growth factor and nerve growth factor enhance sprouting of acetylcholinesterase positive fibres in denervated rat hippocampus, Acta Med. Okayama, 47 (1993) 139-144.
17. Perry, E.K., The cholinergic hypothesis: ten years on, Br. Med. Bull., 42 (1986) 63-69.
18. Satou, T., Imano, M., Akai, F., Hashimoto, S., Itoh, T. and Fujimoto, M., Morphological observation of effects of Cerebrolysin on cultured neuronal cells. In M. Nicolini, P.F. Zatta and B. Coraine (Eds.), Alzheimer's Disease and Related Disorders, Pergamon Press, Oxford, 1993, pp. 195-196.
19. Schwab, M., Otten, U., Agid, Y. and Thoenen, M., Nerve growth factor (NGF) in the rat CNS: absence of specific retrograde transport of horseradish peroxidase, Brain Res., 78 (1979) 1-15.
20. Thoenen, H., Brandtlow, C. and Heumann, R., The physiological function of nerve growth factor in the central nervous system: comparison with the periphery, Rev. Physiol. Biochem. Pharmacol., 109 (1987) 145-178.
21. Williams, L.R., Varon, S., Peterson, G., Wictorin, K., Fischer, W., Bjorklund, A. and Gage, F.H., Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria-fornix transection, Proc. Natl. Acad. Sci. USA, 83 (1986) 9123-9135.
22. Windisch, M. and Piswanger, A., Beeinflussung des Gehirnstoffwechsels von Ratten durch Dauerbehandlung mit einem Peptid-Derivat, Drug Res., 35 (1985) 1353-1356.
23. Windisch, M. and Piswanger, A., Einfluß einer siebentägigen Behandlung mit Cerebrolysin auf die Atmung von Hirnm itochondrien, Neuropsychology, 1 (1987) 83-88.