-
2
-
-
0038147318
-
Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs
-
Martel-Pelletier J, Lajeunesse D, Reboul P, Pelletier JP. Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs. Ann Rheum Dis 2003;62:501-9.
-
(2003)
Ann Rheum Dis
, vol.62
, pp. 501-509
-
-
Martel-Pelletier, J.1
Lajeunesse, D.2
Reboul, P.3
Pelletier, J.P.4
-
6
-
-
0041707878
-
The metabolic effects of inhibitors of 5-lipoxygenase and of cyclooxygenase 1 and 2 are an advancement in the efficacy and safety of anti-inflammatory therapy
-
Celotti F, Durand T. The metabolic effects of inhibitors of 5-lipoxygenase and of cyclooxygenase 1 and 2 are an advancement in the efficacy and safety of anti-inflammatory therapy. Prostaglandins Other Lipid Mediat 2003;71:147-62.
-
(2003)
Prostaglandins Other Lipid Mediat
, vol.71
, pp. 147-162
-
-
Celotti, F.1
Durand, T.2
-
7
-
-
10444239822
-
Study of cross talking between leukotriene and prostaglandin synthetic pathways in human osteoarthritic synovial membranes: Mechanisms of regulation
-
Reboul P, Marcouiller P, Laufer S, Martel-Pelletier J, Pelletier JP. Study of cross talking between leukotriene and prostaglandin synthetic pathways in human osteoarthritic synovial membranes: mechanisms of regulation [abstract]. Ann Rheum Dis 2003;62:H1001.
-
(2003)
Ann Rheum Dis
, vol.62
-
-
Reboul, P.1
Marcouiller, P.2
Laufer, S.3
Martel-Pelletier, J.4
Pelletier, J.P.5
-
8
-
-
0028566488
-
The role of leukotrienes in inflammation
-
Henderson WR Jr. The role of leukotrienes in inflammation. Ann Intern Med 1994;121:684-97.
-
(1994)
Ann Intern Med
, vol.121
, pp. 684-697
-
-
Henderson Jr., W.R.1
-
10
-
-
0023713199
-
Molecular cloning and amino acid sequence of human 5-lipoxygenase
-
Matsumoto T, Funk CD, Radmark O, Hoog JO, Jornvall H, Samuelsson B. Molecular cloning and amino acid sequence of human 5-lipoxygenase. Proc Natl Acad Sci U S A 1988;85:26-30.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 26-30
-
-
Matsumoto, T.1
Funk, C.D.2
Radmark, O.3
Hoog, J.O.4
Jornvall, H.5
Samuelsson, B.6
-
11
-
-
0023776705
-
Cloning of the cDNA for human 5-lipoxygenase
-
Dixon RA, Jones RE, Diehl RE, Bennett CD, Kargman S, Rouzer CA. Cloning of the cDNA for human 5-lipoxygenase. Proc Natl Acad Sci U S A 1988;85:416-20.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 416-420
-
-
Dixon, R.A.1
Jones, R.E.2
Diehl, R.E.3
Bennett, C.D.4
Kargman, S.5
Rouzer, C.A.6
-
12
-
-
0023803150
-
Translocation of 5-lipoxygenase to the membrane in human leukocytes challenged with ionophore A23187
-
Rouzer CA, Kargman S. Translocation of 5-lipoxygenase to the membrane in human leukocytes challenged with ionophore A23187. J Biol Chem 1988;263:10980-8.
-
(1988)
J Biol Chem
, vol.263
, pp. 10980-10988
-
-
Rouzer, C.A.1
Kargman, S.2
-
13
-
-
0025021789
-
Identification and isolation of a membrane protein necessary for leukotriene production
-
Miller DK, Gillard JW, Vickers PJ, Sadowski S, Leveille C, Mancini JA, et al. Identification and isolation of a membrane protein necessary for leukotriene production. Nature 1990;343:278-81.
-
(1990)
Nature
, vol.343
, pp. 278-281
-
-
Miller, D.K.1
Gillard, J.W.2
Vickers, P.J.3
Sadowski, S.4
Leveille, C.5
Mancini, J.A.6
-
14
-
-
0025022489
-
Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis
-
Dixon RA, Diehl RE, Opas E, Rands E, Vickers PJ, Evans JF, et al. Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis. Nature 1990;343:282-4.
-
(1990)
Nature
, vol.343
, pp. 282-284
-
-
Dixon, R.A.1
Diehl, R.E.2
Opas, E.3
Rands, E.4
Vickers, P.J.5
Evans, J.F.6
-
16
-
-
0027488075
-
In vitro release of prostaglandins and leukotrienes from synovial tissue, cartilage, and bone in degenerative joint diseases
-
Wittenberg RH, Willburger RE, Kleemeyer KS, Peskar BA. In vitro release of prostaglandins and leukotrienes from synovial tissue, cartilage, and bone in degenerative joint diseases. Arthritis Rheum 1993;36:1444-50.
-
(1993)
Arthritis Rheum
, vol.36
, pp. 1444-1450
-
-
Wittenberg, R.H.1
Willburger, R.E.2
Kleemeyer, K.S.3
Peskar, B.A.4
-
18
-
-
0029918370
-
Effects of 5-lipoxygenase inhibitors on interleukin production by human synovial tissues in organ culture: Comparison with interleukin-1-synthesis inhibitors
-
Rainsford KD, Ying C, Smith F. Effects of 5-lipoxygenase inhibitors on interleukin production by human synovial tissues in organ culture: comparison with interleukin-1-synthesis inhibitors. J Pharm Pharmacol 1996;48:46-52.
-
(1996)
J Pharm Pharmacol
, vol.48
, pp. 46-52
-
-
Rainsford, K.D.1
Ying, C.2
Smith, F.3
-
19
-
-
0034757607
-
The in vivo dual inhibition of cyclooxygenase and lipoxygenase by ML-3000 reduces the progression of experimental osteoarthritis: Suppression of collagenase 1 and interleukin-1β synthesis
-
Jovanovic DV, Fernandes JC, Martel-Pelletier J, Jolicoeur FC, Reboul P, Laufer S, et al. The in vivo dual inhibition of cyclooxygenase and lipoxygenase by ML-3000 reduces the progression of experimental osteoarthritis: suppression of collagenase 1 and interleukin-1β synthesis. Arthritis Rheum 2001;44:2320-30.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 2320-2330
-
-
Jovanovic, D.V.1
Fernandes, J.C.2
Martel-Pelletier, J.3
Jolicoeur, F.C.4
Reboul, P.5
Laufer, S.6
-
20
-
-
0036009043
-
The synthesis of interleukin-1β, tumour necrosis factor-α and interstitial collagenase (MMP-1) is eicosanoid dependent in human OA synovial membrane explants: Interactions with anti-inflammatory cytokines
-
He W, Pelletier JP, Martel-Pelletier J, Laufer S, Di Battista JA. The synthesis of interleukin-1β, tumour necrosis factor-α and interstitial collagenase (MMP-1) is eicosanoid dependent in human OA synovial membrane explants: interactions with anti-inflammatory cytokines. J Rheumatol 2002;29:546-53.
-
(2002)
J Rheumatol
, vol.29
, pp. 546-553
-
-
He, W.1
Pelletier, J.P.2
Martel-Pelletier, J.3
Laufer, S.4
Di Battista, J.A.5
-
21
-
-
0022465236
-
Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee
-
Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K, et al. Development of criteria for the classification and reporting of osteoarthritis: classification of osteoarthritis of the knee. Arthritis Rheum 1986;29:1039-49.
-
(1986)
Arthritis Rheum
, vol.29
, pp. 1039-1049
-
-
Altman, R.1
Asch, E.2
Bloch, D.3
Bole, G.4
Borenstein, D.5
Brandt, K.6
-
22
-
-
0015046195
-
Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data
-
Mankin HJ, Dorfman H, Lippiello L, Zarins A. Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data. J Bone Joint Surg Am 1971;53:523-37.
-
(1971)
J Bone Joint Surg Am
, vol.53
, pp. 523-537
-
-
Mankin, H.J.1
Dorfman, H.2
Lippiello, L.3
Zarins, A.4
-
23
-
-
0020682296
-
Collagenase and collagenolytic activity in human osteoarthritic cartilage
-
Pelletier JP, Martel-Pelletier J, Howell DS, Ghandur-Mnaymneh L, Enis JE, Woessner JF Jr. Collagenase and collagenolytic activity in human osteoarthritic cartilage. Arthritis Rheum 1983;26:63-8.
-
(1983)
Arthritis Rheum
, vol.26
, pp. 63-68
-
-
Pelletier, J.P.1
Martel-Pelletier, J.2
Howell, D.S.3
Ghandur-Mnaymneh, L.4
Enis, J.E.5
Woessner Jr., J.F.6
-
24
-
-
0021324003
-
Neutral proteases capable of proteoglycan digesting activity in osteoarthritic and normal human articular cartilage
-
Martel-Pelletier J, Pelletier JP, Cloutier JM, Howell DS, Ghandur-Mnaymneh L, Woessner JF Jr. Neutral proteases capable of proteoglycan digesting activity in osteoarthritic and normal human articular cartilage. Arthritis Rheum 1984;27:305-12.
-
(1984)
Arthritis Rheum
, vol.27
, pp. 305-312
-
-
Martel-Pelletier, J.1
Pelletier, J.P.2
Cloutier, J.M.3
Howell, D.S.4
Ghandur-Mnaymneh, L.5
Woessner Jr., J.F.6
-
25
-
-
0029880393
-
The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes: A role in osteoarthritis
-
Reboul P, Pelletier JP, Tardif G, Cloutier JM, Martel-Pelletier J. The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes: a role in osteoarthritis. J Clin Invest 1996;97:2011-9.
-
(1996)
J Clin Invest
, vol.97
, pp. 2011-2019
-
-
Reboul, P.1
Pelletier, J.P.2
Tardif, G.3
Cloutier, J.M.4
Martel-Pelletier, J.5
-
26
-
-
0031945874
-
Effects of tenidap on canine experimental osteoarthritis. II. Study of the expression of collagenase-1 and IL-1β by in situ hybridization
-
Fernandes JC, Martel-Pelletier J, Jovanovic D, Tardif G, Di Battista JA, Lascau-Coman V, et al. Effects of tenidap on canine experimental osteoarthritis. II. Study of the expression of collagenase-1 and IL-1β by in situ hybridization. J Rheumatol 1998;25:951-8.
-
(1998)
J Rheumatol
, vol.25
, pp. 951-958
-
-
Fernandes, J.C.1
Martel-Pelletier, J.2
Jovanovic, D.3
Tardif, G.4
Di Battista, J.A.5
Lascau-Coman, V.6
-
28
-
-
0027006705
-
3 upregulates 5-lipoxygenase metabolism and 5-lipoxygenase activating protein in peripheral blood monocytes as they differentiate into mature macrophages
-
3 upregulates 5-lipoxygenase metabolism and 5-lipoxygenase activating protein in peripheral blood monocytes as they differentiate into mature macrophages. J Lipid Mediat 1993;6:43-51.
-
(1993)
J Lipid Mediat
, vol.6
, pp. 43-51
-
-
Coffey, M.J.1
Gyetko, M.2
Peters-Golden, M.3
-
29
-
-
0027213308
-
Transforming growth factor β upregulates 5-lipoxygenase activity during myeloid cell maturation
-
Steinhilber D, Radmark O, Samuelsson B. Transforming growth factor β upregulates 5-lipoxygenase activity during myeloid cell maturation. Proc Natl Acad Sci U S A 1993;90:5984-8.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 5984-5988
-
-
Steinhilber, D.1
Radmark, O.2
Samuelsson, B.3
-
31
-
-
0033711672
-
Modulation of collagenase 3 in human osteoarthritic cartilage by activation of extracellular transforming growth factor β: Role of furin convertase
-
Moldovan F, Pelletier JP, Mineau F, Dupuis M, Cloutier JM, Martel-Pelletier J. Modulation of collagenase 3 in human osteoarthritic cartilage by activation of extracellular transforming growth factor β: role of furin convertase. Arthritis Rheum 2000;43:2100-9.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2100-2109
-
-
Moldovan, F.1
Pelletier, J.P.2
Mineau, F.3
Dupuis, M.4
Cloutier, J.M.5
Martel-Pelletier, J.6
-
32
-
-
0034901737
-
Expression of vitamin D receptors and matrix metalloproteinases in osteoarthritic cartilage and human articular chondrocytes in vitro
-
Tetlow LC, Woolley DE. Expression of vitamin D receptors and matrix metalloproteinases in osteoarthritic cartilage and human articular chondrocytes in vitro. Osteoarthritis Cartilage 2001;9:423-31.
-
(2001)
Osteoarthritis Cartilage
, vol.9
, pp. 423-431
-
-
Tetlow, L.C.1
Woolley, D.E.2
-
33
-
-
0347320523
-
Treatment with licofelone prevents abnormal subchondral bone cell metabolism in experimental dog osteoarthritis
-
Lajeunesse D, Martel-Pelletier J, Fernandes JC, Laufer S, Pelletier JP. Treatment with licofelone prevents abnormal subchondral bone cell metabolism in experimental dog osteoarthritis. Ann Rheum Dis 2004;63:78-83.
-
(2004)
Ann Rheum Dis
, vol.63
, pp. 78-83
-
-
Lajeunesse, D.1
Martel-Pelletier, J.2
Fernandes, J.C.3
Laufer, S.4
Pelletier, J.P.5
-
34
-
-
0029088388
-
Acute and chronic anti-inflammatory properties of [2,2-dimethyl-6-(4- chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl]-acetic acid
-
Laufer S, Tries S, Augustin J, Elsasser R, Albrecht W, Guserle R, et al. Acute and chronic anti-inflammatory properties of [2,2-dimethyl-6-(4- chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl]-acetic acid. Arzneimittelforschung 1995;45:27-32.
-
(1995)
Arzneimittelforschung
, vol.45
, pp. 27-32
-
-
Laufer, S.1
Tries, S.2
Augustin, J.3
Elsasser, R.4
Albrecht, W.5
Guserle, R.6
-
35
-
-
0034949189
-
Anti-inflammatory drugs: New multitarget compounds to face an old problem - The dual inhibition concept
-
Celotti F, Laufer S. Anti-inflammatory drugs: new multitarget compounds to face an old problem - the dual inhibition concept. Pharmacol Res 2001;43:429-36.
-
(2001)
Pharmacol Res
, vol.43
, pp. 429-436
-
-
Celotti, F.1
Laufer, S.2
-
36
-
-
0031595037
-
4 synthase activities in human chondrocytes: Transcellular biosynthesis of leukotrienes during granulocyte-chondrocyte interaction
-
4 synthase activities in human chondrocytes: transcellular biosynthesis of leukotrienes during granulocyte-chondrocyte interaction. Arthritis Rheum 1998;41:1645-51.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 1645-1651
-
-
Amat, M.1
Diaz, C.2
Vila, L.3
-
37
-
-
0027945466
-
Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene
-
Chen XS, Sheller JR, Johnson EN, Funk CD. Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene. Nature 1994;372:179-82.
-
(1994)
Nature
, vol.372
, pp. 179-182
-
-
Chen, X.S.1
Sheller, J.R.2
Johnson, E.N.3
Funk, C.D.4
-
38
-
-
0028589332
-
Altered inflammatory responses in leukotriene-deficient mice
-
Goulet JL, Snouwaert JN, Latour AM, Coffman TM, Koller BH. Altered inflammatory responses in leukotriene-deficient mice. Proc Natl Acad Sci U S A 1994;91:12852-6.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 12852-12856
-
-
Goulet, J.L.1
Snouwaert, J.N.2
Latour, A.M.3
Coffman, T.M.4
Koller, B.H.5
-
39
-
-
0030589226
-
Leukotriene-deficient mice manifest enhanced lethality from Klebsiella pneumonia in association with decreased alveolar macrophage phagocytic and bactericidal activities
-
Bailie MB, Standiford TJ, Laichalk LL, Coffey MJ, Strieter R, Peters-Golden M. Leukotriene-deficient mice manifest enhanced lethality from Klebsiella pneumonia in association with decreased alveolar macrophage phagocytic and bactericidal activities. J Immunol 1996;157:5221-4.
-
(1996)
J Immunol
, vol.157
, pp. 5221-5224
-
-
Bailie, M.B.1
Standiford, T.J.2
Laichalk, L.L.3
Coffey, M.J.4
Strieter, R.5
Peters-Golden, M.6
-
40
-
-
0030835266
-
5-Lipoxygenase products are necessary for ovalbumin-induced airway responsiveness in mice
-
Irvin CG, Tu YP, Sheller JR, Funk CD. 5-Lipoxygenase products are necessary for ovalbumin-induced airway responsiveness in mice. Am J Physiol 1997;272:L1053-8.
-
(1997)
Am J Physiol
, vol.272
-
-
Irvin, C.G.1
Tu, Y.P.2
Sheller, J.R.3
Funk, C.D.4
-
41
-
-
0034916569
-
Lipid mediator class switching during acute inflammation: Signals in resolution
-
Levy BD, Clish CB, Schmidt B, Gronert K, Serhan CN. Lipid mediator class switching during acute inflammation: signals in resolution. Nat Immunol 2001;2:612-9.
-
(2001)
Nat Immunol
, vol.2
, pp. 612-619
-
-
Levy, B.D.1
Clish, C.B.2
Schmidt, B.3
Gronert, K.4
Serhan, C.N.5
-
42
-
-
0034805725
-
Mechanical stress and nitric oxide influence leukotriene production in cartilage
-
Fermor B, Haribabu B, Weinberg JB, Pisetsky DS, Guilak F. Mechanical stress and nitric oxide influence leukotriene production in cartilage. Biochem Biophys Res Commun 2001;285:806-10.
-
(2001)
Biochem Biophys Res Commun
, vol.285
, pp. 806-810
-
-
Fermor, B.1
Haribabu, B.2
Weinberg, J.B.3
Pisetsky, D.S.4
Guilak, F.5
|