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Volumn 50, Issue 12, 2004, Pages 3925-3933

Regulation of the expression of 5-lipoxygenase-activating protein/5-lipoxygenase and the synthesis of leukotriene B4 in osteoarthritic chondrocytes: Role of transforming growth factor β and eicosanoids

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONATE 5 LIPOXYGENASE ACTIVATING PROTEIN; CALCITRIOL; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; ICOSANOID; INTERSTITIAL COLLAGENASE; LEUKOTRIENE B4; LICOFELONE; LIPOXYGENASE; LIPOXYGENASE 5; MESSENGER RNA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE INHIBITOR; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

EID: 10444285029     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.20632     Document Type: Article
Times cited : (58)

References (42)
  • 2
    • 0038147318 scopus 로고    scopus 로고
    • Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs
    • Martel-Pelletier J, Lajeunesse D, Reboul P, Pelletier JP. Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs. Ann Rheum Dis 2003;62:501-9.
    • (2003) Ann Rheum Dis , vol.62 , pp. 501-509
    • Martel-Pelletier, J.1    Lajeunesse, D.2    Reboul, P.3    Pelletier, J.P.4
  • 4
    • 0027294984 scopus 로고
    • 4 synthesis in patients taking non-steroidal anti-inflammatory drugs
    • 4 synthesis in patients taking non-steroidal anti-inflammatory drugs. Gut 1993;34:742-7.
    • (1993) Gut , vol.34 , pp. 742-747
    • Hudson, N.1    Balsitis, M.2    Everitt, S.3    Hawkey, C.J.4
  • 6
    • 0041707878 scopus 로고    scopus 로고
    • The metabolic effects of inhibitors of 5-lipoxygenase and of cyclooxygenase 1 and 2 are an advancement in the efficacy and safety of anti-inflammatory therapy
    • Celotti F, Durand T. The metabolic effects of inhibitors of 5-lipoxygenase and of cyclooxygenase 1 and 2 are an advancement in the efficacy and safety of anti-inflammatory therapy. Prostaglandins Other Lipid Mediat 2003;71:147-62.
    • (2003) Prostaglandins Other Lipid Mediat , vol.71 , pp. 147-162
    • Celotti, F.1    Durand, T.2
  • 7
    • 10444239822 scopus 로고    scopus 로고
    • Study of cross talking between leukotriene and prostaglandin synthetic pathways in human osteoarthritic synovial membranes: Mechanisms of regulation
    • Reboul P, Marcouiller P, Laufer S, Martel-Pelletier J, Pelletier JP. Study of cross talking between leukotriene and prostaglandin synthetic pathways in human osteoarthritic synovial membranes: mechanisms of regulation [abstract]. Ann Rheum Dis 2003;62:H1001.
    • (2003) Ann Rheum Dis , vol.62
    • Reboul, P.1    Marcouiller, P.2    Laufer, S.3    Martel-Pelletier, J.4    Pelletier, J.P.5
  • 8
    • 0028566488 scopus 로고
    • The role of leukotrienes in inflammation
    • Henderson WR Jr. The role of leukotrienes in inflammation. Ann Intern Med 1994;121:684-97.
    • (1994) Ann Intern Med , vol.121 , pp. 684-697
    • Henderson Jr., W.R.1
  • 12
    • 0023803150 scopus 로고
    • Translocation of 5-lipoxygenase to the membrane in human leukocytes challenged with ionophore A23187
    • Rouzer CA, Kargman S. Translocation of 5-lipoxygenase to the membrane in human leukocytes challenged with ionophore A23187. J Biol Chem 1988;263:10980-8.
    • (1988) J Biol Chem , vol.263 , pp. 10980-10988
    • Rouzer, C.A.1    Kargman, S.2
  • 13
    • 0025021789 scopus 로고
    • Identification and isolation of a membrane protein necessary for leukotriene production
    • Miller DK, Gillard JW, Vickers PJ, Sadowski S, Leveille C, Mancini JA, et al. Identification and isolation of a membrane protein necessary for leukotriene production. Nature 1990;343:278-81.
    • (1990) Nature , vol.343 , pp. 278-281
    • Miller, D.K.1    Gillard, J.W.2    Vickers, P.J.3    Sadowski, S.4    Leveille, C.5    Mancini, J.A.6
  • 14
    • 0025022489 scopus 로고
    • Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis
    • Dixon RA, Diehl RE, Opas E, Rands E, Vickers PJ, Evans JF, et al. Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis. Nature 1990;343:282-4.
    • (1990) Nature , vol.343 , pp. 282-284
    • Dixon, R.A.1    Diehl, R.E.2    Opas, E.3    Rands, E.4    Vickers, P.J.5    Evans, J.F.6
  • 16
    • 0027488075 scopus 로고
    • In vitro release of prostaglandins and leukotrienes from synovial tissue, cartilage, and bone in degenerative joint diseases
    • Wittenberg RH, Willburger RE, Kleemeyer KS, Peskar BA. In vitro release of prostaglandins and leukotrienes from synovial tissue, cartilage, and bone in degenerative joint diseases. Arthritis Rheum 1993;36:1444-50.
    • (1993) Arthritis Rheum , vol.36 , pp. 1444-1450
    • Wittenberg, R.H.1    Willburger, R.E.2    Kleemeyer, K.S.3    Peskar, B.A.4
  • 18
    • 0029918370 scopus 로고    scopus 로고
    • Effects of 5-lipoxygenase inhibitors on interleukin production by human synovial tissues in organ culture: Comparison with interleukin-1-synthesis inhibitors
    • Rainsford KD, Ying C, Smith F. Effects of 5-lipoxygenase inhibitors on interleukin production by human synovial tissues in organ culture: comparison with interleukin-1-synthesis inhibitors. J Pharm Pharmacol 1996;48:46-52.
    • (1996) J Pharm Pharmacol , vol.48 , pp. 46-52
    • Rainsford, K.D.1    Ying, C.2    Smith, F.3
  • 19
    • 0034757607 scopus 로고    scopus 로고
    • The in vivo dual inhibition of cyclooxygenase and lipoxygenase by ML-3000 reduces the progression of experimental osteoarthritis: Suppression of collagenase 1 and interleukin-1β synthesis
    • Jovanovic DV, Fernandes JC, Martel-Pelletier J, Jolicoeur FC, Reboul P, Laufer S, et al. The in vivo dual inhibition of cyclooxygenase and lipoxygenase by ML-3000 reduces the progression of experimental osteoarthritis: suppression of collagenase 1 and interleukin-1β synthesis. Arthritis Rheum 2001;44:2320-30.
    • (2001) Arthritis Rheum , vol.44 , pp. 2320-2330
    • Jovanovic, D.V.1    Fernandes, J.C.2    Martel-Pelletier, J.3    Jolicoeur, F.C.4    Reboul, P.5    Laufer, S.6
  • 20
    • 0036009043 scopus 로고    scopus 로고
    • The synthesis of interleukin-1β, tumour necrosis factor-α and interstitial collagenase (MMP-1) is eicosanoid dependent in human OA synovial membrane explants: Interactions with anti-inflammatory cytokines
    • He W, Pelletier JP, Martel-Pelletier J, Laufer S, Di Battista JA. The synthesis of interleukin-1β, tumour necrosis factor-α and interstitial collagenase (MMP-1) is eicosanoid dependent in human OA synovial membrane explants: interactions with anti-inflammatory cytokines. J Rheumatol 2002;29:546-53.
    • (2002) J Rheumatol , vol.29 , pp. 546-553
    • He, W.1    Pelletier, J.P.2    Martel-Pelletier, J.3    Laufer, S.4    Di Battista, J.A.5
  • 21
    • 0022465236 scopus 로고
    • Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee
    • Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K, et al. Development of criteria for the classification and reporting of osteoarthritis: classification of osteoarthritis of the knee. Arthritis Rheum 1986;29:1039-49.
    • (1986) Arthritis Rheum , vol.29 , pp. 1039-1049
    • Altman, R.1    Asch, E.2    Bloch, D.3    Bole, G.4    Borenstein, D.5    Brandt, K.6
  • 22
    • 0015046195 scopus 로고
    • Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data
    • Mankin HJ, Dorfman H, Lippiello L, Zarins A. Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data. J Bone Joint Surg Am 1971;53:523-37.
    • (1971) J Bone Joint Surg Am , vol.53 , pp. 523-537
    • Mankin, H.J.1    Dorfman, H.2    Lippiello, L.3    Zarins, A.4
  • 25
    • 0029880393 scopus 로고    scopus 로고
    • The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes: A role in osteoarthritis
    • Reboul P, Pelletier JP, Tardif G, Cloutier JM, Martel-Pelletier J. The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes: a role in osteoarthritis. J Clin Invest 1996;97:2011-9.
    • (1996) J Clin Invest , vol.97 , pp. 2011-2019
    • Reboul, P.1    Pelletier, J.P.2    Tardif, G.3    Cloutier, J.M.4    Martel-Pelletier, J.5
  • 26
    • 0031945874 scopus 로고    scopus 로고
    • Effects of tenidap on canine experimental osteoarthritis. II. Study of the expression of collagenase-1 and IL-1β by in situ hybridization
    • Fernandes JC, Martel-Pelletier J, Jovanovic D, Tardif G, Di Battista JA, Lascau-Coman V, et al. Effects of tenidap on canine experimental osteoarthritis. II. Study of the expression of collagenase-1 and IL-1β by in situ hybridization. J Rheumatol 1998;25:951-8.
    • (1998) J Rheumatol , vol.25 , pp. 951-958
    • Fernandes, J.C.1    Martel-Pelletier, J.2    Jovanovic, D.3    Tardif, G.4    Di Battista, J.A.5    Lascau-Coman, V.6
  • 28
    • 0027006705 scopus 로고
    • 3 upregulates 5-lipoxygenase metabolism and 5-lipoxygenase activating protein in peripheral blood monocytes as they differentiate into mature macrophages
    • 3 upregulates 5-lipoxygenase metabolism and 5-lipoxygenase activating protein in peripheral blood monocytes as they differentiate into mature macrophages. J Lipid Mediat 1993;6:43-51.
    • (1993) J Lipid Mediat , vol.6 , pp. 43-51
    • Coffey, M.J.1    Gyetko, M.2    Peters-Golden, M.3
  • 29
    • 0027213308 scopus 로고
    • Transforming growth factor β upregulates 5-lipoxygenase activity during myeloid cell maturation
    • Steinhilber D, Radmark O, Samuelsson B. Transforming growth factor β upregulates 5-lipoxygenase activity during myeloid cell maturation. Proc Natl Acad Sci U S A 1993;90:5984-8.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 5984-5988
    • Steinhilber, D.1    Radmark, O.2    Samuelsson, B.3
  • 31
    • 0033711672 scopus 로고    scopus 로고
    • Modulation of collagenase 3 in human osteoarthritic cartilage by activation of extracellular transforming growth factor β: Role of furin convertase
    • Moldovan F, Pelletier JP, Mineau F, Dupuis M, Cloutier JM, Martel-Pelletier J. Modulation of collagenase 3 in human osteoarthritic cartilage by activation of extracellular transforming growth factor β: role of furin convertase. Arthritis Rheum 2000;43:2100-9.
    • (2000) Arthritis Rheum , vol.43 , pp. 2100-2109
    • Moldovan, F.1    Pelletier, J.P.2    Mineau, F.3    Dupuis, M.4    Cloutier, J.M.5    Martel-Pelletier, J.6
  • 32
    • 0034901737 scopus 로고    scopus 로고
    • Expression of vitamin D receptors and matrix metalloproteinases in osteoarthritic cartilage and human articular chondrocytes in vitro
    • Tetlow LC, Woolley DE. Expression of vitamin D receptors and matrix metalloproteinases in osteoarthritic cartilage and human articular chondrocytes in vitro. Osteoarthritis Cartilage 2001;9:423-31.
    • (2001) Osteoarthritis Cartilage , vol.9 , pp. 423-431
    • Tetlow, L.C.1    Woolley, D.E.2
  • 33
    • 0347320523 scopus 로고    scopus 로고
    • Treatment with licofelone prevents abnormal subchondral bone cell metabolism in experimental dog osteoarthritis
    • Lajeunesse D, Martel-Pelletier J, Fernandes JC, Laufer S, Pelletier JP. Treatment with licofelone prevents abnormal subchondral bone cell metabolism in experimental dog osteoarthritis. Ann Rheum Dis 2004;63:78-83.
    • (2004) Ann Rheum Dis , vol.63 , pp. 78-83
    • Lajeunesse, D.1    Martel-Pelletier, J.2    Fernandes, J.C.3    Laufer, S.4    Pelletier, J.P.5
  • 34
    • 0029088388 scopus 로고
    • Acute and chronic anti-inflammatory properties of [2,2-dimethyl-6-(4- chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl]-acetic acid
    • Laufer S, Tries S, Augustin J, Elsasser R, Albrecht W, Guserle R, et al. Acute and chronic anti-inflammatory properties of [2,2-dimethyl-6-(4- chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl]-acetic acid. Arzneimittelforschung 1995;45:27-32.
    • (1995) Arzneimittelforschung , vol.45 , pp. 27-32
    • Laufer, S.1    Tries, S.2    Augustin, J.3    Elsasser, R.4    Albrecht, W.5    Guserle, R.6
  • 35
    • 0034949189 scopus 로고    scopus 로고
    • Anti-inflammatory drugs: New multitarget compounds to face an old problem - The dual inhibition concept
    • Celotti F, Laufer S. Anti-inflammatory drugs: new multitarget compounds to face an old problem - the dual inhibition concept. Pharmacol Res 2001;43:429-36.
    • (2001) Pharmacol Res , vol.43 , pp. 429-436
    • Celotti, F.1    Laufer, S.2
  • 36
    • 0031595037 scopus 로고    scopus 로고
    • 4 synthase activities in human chondrocytes: Transcellular biosynthesis of leukotrienes during granulocyte-chondrocyte interaction
    • 4 synthase activities in human chondrocytes: transcellular biosynthesis of leukotrienes during granulocyte-chondrocyte interaction. Arthritis Rheum 1998;41:1645-51.
    • (1998) Arthritis Rheum , vol.41 , pp. 1645-1651
    • Amat, M.1    Diaz, C.2    Vila, L.3
  • 37
    • 0027945466 scopus 로고
    • Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene
    • Chen XS, Sheller JR, Johnson EN, Funk CD. Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene. Nature 1994;372:179-82.
    • (1994) Nature , vol.372 , pp. 179-182
    • Chen, X.S.1    Sheller, J.R.2    Johnson, E.N.3    Funk, C.D.4
  • 39
    • 0030589226 scopus 로고    scopus 로고
    • Leukotriene-deficient mice manifest enhanced lethality from Klebsiella pneumonia in association with decreased alveolar macrophage phagocytic and bactericidal activities
    • Bailie MB, Standiford TJ, Laichalk LL, Coffey MJ, Strieter R, Peters-Golden M. Leukotriene-deficient mice manifest enhanced lethality from Klebsiella pneumonia in association with decreased alveolar macrophage phagocytic and bactericidal activities. J Immunol 1996;157:5221-4.
    • (1996) J Immunol , vol.157 , pp. 5221-5224
    • Bailie, M.B.1    Standiford, T.J.2    Laichalk, L.L.3    Coffey, M.J.4    Strieter, R.5    Peters-Golden, M.6
  • 40
    • 0030835266 scopus 로고    scopus 로고
    • 5-Lipoxygenase products are necessary for ovalbumin-induced airway responsiveness in mice
    • Irvin CG, Tu YP, Sheller JR, Funk CD. 5-Lipoxygenase products are necessary for ovalbumin-induced airway responsiveness in mice. Am J Physiol 1997;272:L1053-8.
    • (1997) Am J Physiol , vol.272
    • Irvin, C.G.1    Tu, Y.P.2    Sheller, J.R.3    Funk, C.D.4
  • 41
    • 0034916569 scopus 로고    scopus 로고
    • Lipid mediator class switching during acute inflammation: Signals in resolution
    • Levy BD, Clish CB, Schmidt B, Gronert K, Serhan CN. Lipid mediator class switching during acute inflammation: signals in resolution. Nat Immunol 2001;2:612-9.
    • (2001) Nat Immunol , vol.2 , pp. 612-619
    • Levy, B.D.1    Clish, C.B.2    Schmidt, B.3    Gronert, K.4    Serhan, C.N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.