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Volumn 18, Issue 3, 2008, Pages 225-233

Potent knockdown of the X RNA of hepatitis B by a novel chimeric siRNA-ribozyme construct and modulation of intracellular target RNA by selectively disabled mutants

Author keywords

[No Author keywords available]

Indexed keywords

DNA; HAMMERHEAD RIBOZYME; RIBOZYME; RNA; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; VIRUS PROTEIN; VIRUS RNA;

EID: 51849108210     PISSN: 15454576     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.2008.0134     Document Type: Article
Times cited : (2)

References (33)
  • 1
    • 0041304776 scopus 로고    scopus 로고
    • si-RNAs, ribozymes, and RNA decoys in modeling stem cell based gene therapy for HIV/AIDS
    • AKKINA, R., BANERJEA, A., BAI, J., ANDERSON, J., Li, M. J., and ROSSI, J.J. (2003). si-RNAs, ribozymes, and RNA decoys in modeling stem cell based gene therapy for HIV/AIDS. Anticancer Res. 23, 1997-1905.
    • (2003) Anticancer Res , vol.23 , pp. 1997-1905
    • AKKINA, R.1    BANERJEA, A.2    BAI, J.3    ANDERSON, J.4    Li, M.J.5    ROSSI, J.J.6
  • 2
    • 1642564331 scopus 로고    scopus 로고
    • Bispecific short hairpin siRNA constructs targeted to CD4, CXCR4 and CCR5 confer HIV-1 resistance
    • ANDERSON, J., BANERJEA, A., and AKKINA, R. (2003). Bispecific short hairpin siRNA constructs targeted to CD4, CXCR4 and CCR5 confer HIV-1 resistance. Oligonucleotides 13, 303-312.
    • (2003) Oligonucleotides , vol.13 , pp. 303-312
    • ANDERSON, J.1    BANERJEA, A.2    AKKINA, R.3
  • 3
    • 33845221484 scopus 로고    scopus 로고
    • ANDERSON, J., and AKKINA, R. (2005). HIV-1 resistance conferred by siRNA cosuppression of CXCR4 and CCR5 coreceptors by a bi-specific lentiviral vector. AIDS Res. Ther. 2, 1.
    • ANDERSON, J., and AKKINA, R. (2005). HIV-1 resistance conferred by siRNA cosuppression of CXCR4 and CCR5 coreceptors by a bi-specific lentiviral vector. AIDS Res. Ther. 2, 1.
  • 4
    • 0025005789 scopus 로고
    • Reovirus protein σ1 translated in vitro as well as truncated derivatives of that lack up to two-thirds of its C-terminal portion, exists as two major tetramolecular species that differ in electrophoretic mobility
    • BANERJEA, A.C., and JOKLIK, W.K. (1990). Reovirus protein σ1 translated in vitro as well as truncated derivatives of that lack up to two-thirds of its C-terminal portion, exists as two major tetramolecular species that differ in electrophoretic mobility. Virology 179, 460-462.
    • (1990) Virology , vol.179 , pp. 460-462
    • BANERJEA, A.C.1    JOKLIK, W.K.2
  • 5
    • 23644454894 scopus 로고    scopus 로고
    • BANERJEA, A., MINGG-JI LI, REMLING, L., ROSSI, J.J., and AKKINA, R. (2004). Lentiviral transduction of Tar Decoy and CCR5 ribozyme into CD34+ progenitor cells and derivation of HIV-1 resistant T cells and macrophages. AIDS Res. Ther. 1, 2.
    • BANERJEA, A., MINGG-JI LI, REMLING, L., ROSSI, J.J., and AKKINA, R. (2004). Lentiviral transduction of Tar Decoy and CCR5 ribozyme into CD34+ progenitor cells and derivation of HIV-1 resistant T cells and macrophages. AIDS Res. Ther. 1, 2.
  • 7
    • 35348911812 scopus 로고    scopus 로고
    • Brother in arms: DNA enzymes, short interfering RNA, and the emerging wave of small-molecule nucleic acid based gene silencing strategies
    • BHINDI, R., FAHMY, R.G., LOWE, H.C., CHESTERMAN, C.N., DASS, C.R., CAIRNS, M.J., SARAVOLAC, E.G., SUN, L-Q., KHACHIGIAN, L.M. (2007). Brother in arms: DNA enzymes, short interfering RNA, and the emerging wave of small-molecule nucleic acid based gene silencing strategies. Am J Path. 171, 1079-1088.
    • (2007) Am J Path , vol.171 , pp. 1079-1088
    • BHINDI, R.1    FAHMY, R.G.2    LOWE, H.C.3    CHESTERMAN, C.N.4    DASS, C.R.5    CAIRNS, M.J.6    SARAVOLAC, E.G.7    SUN, L.-Q.8    KHACHIGIAN, L.M.9
  • 9
    • 0012756249 scopus 로고    scopus 로고
    • RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase
    • DONZE, O., and PICARD, D. (2002). RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase. Nucleic Acids Res. 30, e45.
    • (2002) Nucleic Acids Res , vol.30
    • DONZE, O.1    PICARD, D.2
  • 10
    • 0032475985 scopus 로고    scopus 로고
    • Sequence-specific cleavage of HIV-1 coreceptor-CCR5 gene by a hammerhead ribozyme and a DNA-enzyme: Inhibition of the coreceptor function by DNA-enzyme
    • GOILA, R., and BANERJEA, A.C. (1998). Sequence-specific cleavage of HIV-1 coreceptor-CCR5 gene by a hammerhead ribozyme and a DNA-enzyme: Inhibition of the coreceptor function by DNA-enzyme. FEBS Lett. 436, 233-238.
    • (1998) FEBS Lett , vol.436 , pp. 233-238
    • GOILA, R.1    BANERJEA, A.C.2
  • 11
    • 0035253125 scopus 로고    scopus 로고
    • Inhibition of hepatitis B virus X gene expression by novel DNA enzymes
    • GOILA, R., and BANERJEA, A.C. (2001) Inhibition of hepatitis B virus X gene expression by novel DNA enzymes. Biochemical J. 353, 701-708.
    • (2001) Biochemical J , vol.353 , pp. 701-708
    • GOILA, R.1    BANERJEA, A.C.2
  • 12
    • 12444281735 scopus 로고    scopus 로고
    • Sequence specific cleavage of hepatitis X RNA in cis and trans by novel monotarget and multitarget hammerhead motif-containing ribozymes
    • GOILA, R., and BANERJEA, A.C. (2004). Sequence specific cleavage of hepatitis X RNA in cis and trans by novel monotarget and multitarget hammerhead motif-containing ribozymes. Oligonucleotides 14, 249-262.
    • (2004) Oligonucleotides , vol.14 , pp. 249-262
    • GOILA, R.1    BANERJEA, A.C.2
  • 13
    • 0035929642 scopus 로고    scopus 로고
    • The hepatitis B virus X protein induces HIV-1 replication and transcription in synergy with T-cell activating signals. Functional roles of Nf-kappaB/NF-AT and SP1-binding sites in the HIV-1 long terminal repeat promoter
    • GOMEZ-GANZALO, M., CARRETERO, M., RULLAS, J., LARA-PEZZI, E., ARAMBURU, J., BERKHOUT, B., ALCAMI. J., and LOPEZ-CABBERA, M. (2001). The hepatitis B virus X protein induces HIV-1 replication and transcription in synergy with T-cell activating signals. Functional roles of Nf-kappaB/NF-AT and SP1-binding sites in the HIV-1 long terminal repeat promoter. J Biol. Chem. 276, 35435-35443.
    • (2001) J Biol. Chem , vol.276 , pp. 35435-35443
    • GOMEZ-GANZALO, M.1    CARRETERO, M.2    RULLAS, J.3    LARA-PEZZI, E.4    ARAMBURU, J.5    BERKHOUT, B.6    ALCAMI, J.7    LOPEZ-CABBERA, M.8
  • 14
    • 34250843870 scopus 로고    scopus 로고
    • X protein of hepatitis B virus potently activates HIV-1 subtype C-LTR promoter: Implications for faster spread of HIV-1 subtype-C
    • GUPTA, N., SOOD, V., BANO, A.S., and BANERJEA, A.C. (2007). X protein of hepatitis B virus potently activates HIV-1 subtype C-LTR promoter: implications for faster spread of HIV-1 subtype-C. AIDS 21, 1491-1492.
    • (2007) AIDS , vol.21 , pp. 1491-1492
    • GUPTA, N.1    SOOD, V.2    BANO, A.S.3    BANERJEA, A.C.4
  • 15
    • 51849094522 scopus 로고    scopus 로고
    • GUPTA, N., BANO, A.S., SHARMA, Y., SOOD, V., and BANERJEA, A.C. (2008). Potent intracellular knock down of Hepatitis B virus X RNA by catalytic hammerhead ribozymes or DNA-enzymes with antisense DNA-oligonucleotides or 10-23 DNA-enzymes that powerfully augment in vitro sequence-specific cleavage activities. The Open Biotechnology Journal, 2, 1-12. (Open Access) The URL to access to the article http://www.bentham.org/open/tobiotj/openaccess2.htm
    • GUPTA, N., BANO, A.S., SHARMA, Y., SOOD, V., and BANERJEA, A.C. (2008). Potent intracellular knock down of Hepatitis B virus X RNA by catalytic hammerhead ribozymes or DNA-enzymes with antisense DNA-oligonucleotides or 10-23 DNA-enzymes that powerfully augment in vitro sequence-specific cleavage activities. The Open Biotechnology Journal, 2, 1-12. (Open Access) The URL to access to the article http://www.bentham.org/open/tobiotj/openaccess2.htm
  • 16
    • 3042732096 scopus 로고    scopus 로고
    • Directed evolution of nucleic acid enzymes
    • JOYCE, G.F. (2004). Directed evolution of nucleic acid enzymes. Ann. Rev. Biochem. 73, 791-736.
    • (2004) Ann. Rev. Biochem , vol.73 , pp. 791-736
    • JOYCE, G.F.1
  • 17
    • 0029937060 scopus 로고    scopus 로고
    • A truncated mutant (residues 58-140) of the hepatitis B virus X protein retains transactivation function
    • KUMAR, V., JAYASURYAN, N., and KUMAR, R. (1996). A truncated mutant (residues 58-140) of the hepatitis B virus X protein retains transactivation function. Proc Natl Acad Sci USA 93, 5647-5652.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5647-5652
    • KUMAR, V.1    JAYASURYAN, N.2    KUMAR, R.3
  • 18
    • 0036510780 scopus 로고    scopus 로고
    • Comparative study of DNA enzymes and ribozymes against the same full-length messenger RNA of the vanilloid receptor subtype 1
    • KURRECK, J., BIEBER, B., JAHNEL, R., and ERDMANN, V.A. (2002). Comparative study of DNA enzymes and ribozymes against the same full-length messenger RNA of the vanilloid receptor subtype 1. J. Biol. Chem. 277, 7099-8007.
    • (2002) J. Biol. Chem , vol.277 , pp. 7099-8007
    • KURRECK, J.1    BIEBER, B.2    JAHNEL, R.3    ERDMANN, V.A.4
  • 19
    • 0037733977 scopus 로고    scopus 로고
    • Antisense technologies: Improvement through novel chemical modifications
    • KURRECK, J. (2003). Antisense technologies: Improvement through novel chemical modifications. Eur. J. Biochem. 270, 1628-1644.
    • (2003) Eur. J. Biochem , vol.270 , pp. 1628-1644
    • KURRECK, J.1
  • 20
    • 0036311178 scopus 로고    scopus 로고
    • Gene silencing in mammalian cells by preformed small RNA duplexes
    • LEIRDAL, M., and SIOUD, M. (2002). Gene silencing in mammalian cells by preformed small RNA duplexes. Biochem. Biophys. Res. Comm. 295, 744-748.
    • (2002) Biochem. Biophys. Res. Comm , vol.295 , pp. 744-748
    • LEIRDAL, M.1    SIOUD, M.2
  • 21
    • 36849026128 scopus 로고    scopus 로고
    • Applications of RNA interference in mammalian systems
    • MARTIM, S.E., and CAPLEIN, N.J. (2007). Applications of RNA interference in mammalian systems. Annu. Rev. Genomics Hum. Genet. 8, 81-108.
    • (2007) Annu. Rev. Genomics Hum. Genet , vol.8 , pp. 81-108
    • MARTIM, S.E.1    CAPLEIN, N.J.2
  • 22
    • 0037032933 scopus 로고    scopus 로고
    • Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication
    • MARTINEZ, M.A., GUTIERREZ, A., ARMAND-UGON, M., BLANCO, J., PARERA, M., GOMEZ, J., CLOTET, B., and ESTE. J.A. (2002). Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication. AIDS 16, 2385-2390.
    • (2002) AIDS , vol.16 , pp. 2385-2390
    • MARTINEZ, M.A.1    GUTIERREZ, A.2    ARMAND-UGON, M.3    BLANCO, J.4    PARERA, M.5    GOMEZ, J.6    CLOTET, B.7    ESTE, J.A.8
  • 23
    • 0030838518 scopus 로고    scopus 로고
    • Defective HIV-1 provirus encoding a multitarget ribozyme inhibits accumulation of spliced and unspliced HIV-1 mRNAs, reduces infectivity of viral progeny and protects the cells from pathogenesis
    • PAIK, S., BANERJEA, A., HARMISON, G.G., CHEN, C.J., and SCHUBERT, M. (1997). Defective HIV-1 provirus encoding a multitarget ribozyme inhibits accumulation of spliced and unspliced HIV-1 mRNAs, reduces infectivity of viral progeny and protects the cells from pathogenesis. Human Gene Ther. 8, 1115-1124.
    • (1997) Human Gene Ther , vol.8 , pp. 1115-1124
    • PAIK, S.1    BANERJEA, A.2    HARMISON, G.G.3    CHEN, C.J.4    SCHUBERT, M.5
  • 24
    • 33744482067 scopus 로고    scopus 로고
    • Assessment of an anti-HIV-1 combination gene therapy strategy using antisense RNA and multimeric hammerhead ribozymes
    • RAMEZANI, A., MA, X.Z., AMELI, M., ARORA, A., and JOSHI, S. (2006). Assessment of an anti-HIV-1 combination gene therapy strategy using antisense RNA and multimeric hammerhead ribozymes. Front. Biosci. 11, 2940-2948.
    • (2006) Front. Biosci , vol.11 , pp. 2940-2948
    • RAMEZANI, A.1    MA, X.Z.2    AMELI, M.3    ARORA, A.4    JOSHI, S.5
  • 25
    • 0028306247 scopus 로고
    • Molecular events in pathogenesis of hepadnaviruses associated hepatocellular carcinoma
    • ROBINSON, W.S. (1994). Molecular events in pathogenesis of hepadnaviruses associated hepatocellular carcinoma. Annu. Rev. Med. 45, 297-223.
    • (1994) Annu. Rev. Med , vol.45 , pp. 297-223
    • ROBINSON, W.S.1
  • 26
    • 33646848909 scopus 로고    scopus 로고
    • RNAi as a treatment for HIV-1 infection
    • ROSSI, J.J. (2006). RNAi as a treatment for HIV-1 infection. Biotechniques Suppl: 25-29.
    • (2006) Biotechniques Suppl , pp. 25-29
    • ROSSI, J.J.1
  • 27
    • 1842579654 scopus 로고    scopus 로고
    • RNAi applications in mammalian cells
    • SCHERER, L., and ROSSI, J. J. (2004). RNAi applications in mammalian cells. Biotechniques 36, 557-561.
    • (2004) Biotechniques , vol.36 , pp. 557-561
    • SCHERER, L.1    ROSSI, J.J.2
  • 29
    • 33645809534 scopus 로고    scopus 로고
    • Oligonucleotide-based antiviral strategies
    • SCHUBERT, S., and KURRECK, J. (2006). Oligonucleotide-based antiviral strategies. Handb. Exp. Pharmacol. 173, 261-287.
    • (2006) Handb. Exp. Pharmacol , vol.173 , pp. 261-287
    • SCHUBERT, S.1    KURRECK, J.2
  • 30
    • 0035957359 scopus 로고    scopus 로고
    • Ribozymes that cleave reovirus genome segments S1 also protect cells from pathogenesis caused by reovirus infection
    • SHAHI, S., SHANMUGASUNDARAM, G.K., and BANERJEA, A.C. (2001). Ribozymes that cleave reovirus genome segments S1 also protect cells from pathogenesis caused by reovirus infection. Proc. Nat. Acad. Sci. USA 98, 4101-4106.
    • (2001) Proc. Nat. Acad. Sci. USA , vol.98 , pp. 4101-4106
    • SHAHI, S.1    SHANMUGASUNDARAM, G.K.2    BANERJEA, A.C.3
  • 31
    • 34247533679 scopus 로고    scopus 로고
    • DNA-enzyme mediated cleavage of human immunodeficiency virus type 1 Gag RNA is significantly augmented by antisense-DNA molecules targeted to hybridize close to the cleavage site
    • SOOD, V., GUPTA, N., BANO, A.S., and BANERJEA, A.C. (2007). DNA-enzyme mediated cleavage of human immunodeficiency virus type 1 Gag RNA is significantly augmented by antisense-DNA molecules targeted to hybridize close to the cleavage site. Oligonucleotides 17, 113-121.
    • (2007) Oligonucleotides , vol.17 , pp. 113-121
    • SOOD, V.1    GUPTA, N.2    BANO, A.S.3    BANERJEA, A.C.4
  • 32
    • 33748317801 scopus 로고    scopus 로고
    • Potent inhibition of HIV-1 gene expression and TAT-mediated apoptosis in human T cells by novel mono- and multitarget anti-TAT/Rev/Env ribozymes and a general purpose RNA-cleaving DNA-enzyme
    • UNWALLA, H. CHAKRABORTI, S., SOOD, V., GUPTA, N., and BANERJEA, A.C. (2006). Potent inhibition of HIV-1 gene expression and TAT-mediated apoptosis in human T cells by novel mono- and multitarget anti-TAT/Rev/Env ribozymes and a general purpose RNA-cleaving DNA-enzyme. Antiviral Res. 72, 134-144.
    • (2006) Antiviral Res , vol.72 , pp. 134-144
    • UNWALLA, H.1    CHAKRABORTI, S.2    SOOD, V.3    GUPTA, N.4    BANERJEA, A.C.5
  • 33
    • 48349105059 scopus 로고    scopus 로고
    • ZHOU, J, LI, H., ZAIA J., and ROSSI, J.J. (2008). Novel dual inhibitory function apatamer-siRNA delivery system for HIV-1 therapy. Mol. Ther. May 6 [Epub ahead of print].
    • ZHOU, J, LI, H., ZAIA J., and ROSSI, J.J. (2008). Novel dual inhibitory function apatamer-siRNA delivery system for HIV-1 therapy. Mol. Ther. May 6 [Epub ahead of print].


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