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Volumn 60, Issue 5, 2008, Pages 692-702

The short chain fatty acid butyrate induces promoter demethylation and reactivation of RARβ2 in colon cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; BUTYRIC ACID; DNA METHYLTRANSFERASE INHIBITOR; GENISTEIN; HISTONE DEACETYLASE 1; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID RECEPTOR BETA; SHORT CHAIN FATTY ACID;

EID: 51849099492     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1080/01635580802008278     Document Type: Article
Times cited : (48)

References (70)
  • 1
    • 34547897023 scopus 로고    scopus 로고
    • Histone deacetylases and cancer
    • Glozak MA and Seto E: Histone deacetylases and cancer. Oncogene 26, 5420-5432, 2007.
    • (2007) Oncogene , vol.26 , pp. 5420-5432
    • Glozak, M.A.1    Seto, E.2
  • 2
    • 36148950997 scopus 로고    scopus 로고
    • FDA approval summary: Vorinostat for treatment of advanced primary cutaneous T-cell lymphoma
    • Mann BS, Johnson JR, Cohen MH, Justice R, and Pazdur R: FDA approval summary: vorinostat for treatment of advanced primary cutaneous T-cell lymphoma. Oncologist 12, 1247-1252, 2007.
    • (2007) Oncologist , vol.12 , pp. 1247-1252
    • Mann, B.S.1    Johnson, J.R.2    Cohen, M.H.3    Justice, R.4    Pazdur, R.5
  • 3
    • 34547683194 scopus 로고    scopus 로고
    • Phase IIb multicenter trial of vorinostat in patients with persistent, progressive, or treatment refractory cutaneous T-cell lymphoma
    • Olsen EA, Kim YH, Kuzel TM, Pacheco TR, Foss FM, et al.: Phase IIb multicenter trial of vorinostat in patients with persistent, progressive, or treatment refractory cutaneous T-cell lymphoma. J Clin Oncol 25, 3109-3115, 2007.
    • (2007) J Clin Oncol , vol.25 , pp. 3109-3115
    • Olsen, E.A.1    Kim, Y.H.2    Kuzel, T.M.3    Pacheco, T.R.4    Foss, F.M.5
  • 4
    • 34247860871 scopus 로고    scopus 로고
    • Vorinostat for treatment of cutaneous manifestations of advanced primary cutaneous T-cell lymphoma
    • Mann BS, Johnson JR, He K, Sridhara R, Abraham S, et al.: Vorinostat for treatment of cutaneous manifestations of advanced primary cutaneous T-cell lymphoma. Clin Cancer Res 13, 2318-2322, 2007.
    • (2007) Clin Cancer Res , vol.13 , pp. 2318-2322
    • Mann, B.S.1    Johnson, J.R.2    He, K.3    Sridhara, R.4    Abraham, S.5
  • 5
    • 34748877735 scopus 로고    scopus 로고
    • Inhibition of histone deacetylation: A strategy for tumor radiosensitization
    • Camphausen K and Tofilon PJ: Inhibition of histone deacetylation: a strategy for tumor radiosensitization. J Clin Oncol 25, 4051-4056, 2007.
    • (2007) J Clin Oncol , vol.25 , pp. 4051-4056
    • Camphausen, K.1    Tofilon, P.J.2
  • 6
    • 34547653955 scopus 로고    scopus 로고
    • Synergistic in vivo antitumor effect of the histone deacetylase inhibitor MS-275 in combination with interleukin 2 in a murine model of renal cell carcinoma
    • Kato Y, Yoshimura K, Shin T, Verheul H, Hammers H, et al.: Synergistic in vivo antitumor effect of the histone deacetylase inhibitor MS-275 in combination with interleukin 2 in a murine model of renal cell carcinoma. Clin Cancer Res 13, 4538-4546, 2007.
    • (2007) Clin Cancer Res , vol.13 , pp. 4538-4546
    • Kato, Y.1    Yoshimura, K.2    Shin, T.3    Verheul, H.4    Hammers, H.5
  • 7
    • 33846804139 scopus 로고    scopus 로고
    • Antitumor effect of the histone deacetylase inhibitor LAQ824 in combination with 13-cis-retinoic acid in human malignant melanoma
    • Kato Y, Salumbides BC, Wang XF, Qian DZ, Williams S, et al.: Antitumor effect of the histone deacetylase inhibitor LAQ824 in combination with 13-cis-retinoic acid in human malignant melanoma. Mol Cancer Ther 6, 70-81, 2007.
    • (2007) Mol Cancer Ther , vol.6 , pp. 70-81
    • Kato, Y.1    Salumbides, B.C.2    Wang, X.F.3    Qian, D.Z.4    Williams, S.5
  • 8
    • 0035810045 scopus 로고    scopus 로고
    • Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A
    • Rashid SF, Moore JS, Walker E, Driver PM, Engel J, et al.: Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A. Oncogene 20, 1860-1872, 2001.
    • (2001) Oncogene , vol.20 , pp. 1860-1872
    • Rashid, S.F.1    Moore, J.S.2    Walker, E.3    Driver, P.M.4    Engel, J.5
  • 9
    • 0036746906 scopus 로고    scopus 로고
    • Antineoplastic action of 5-aza-2-deoxycytidine and phenylbutyrate on human lung carcinoma cells
    • Boivin AJ, Momparler LF, Hurtubise A, and Momparler RL: Antineoplastic action of 5-aza-2-deoxycytidine and phenylbutyrate on human lung carcinoma cells. Anticancer Drugs 13, 869-874, 2002.
    • (2002) Anticancer Drugs , vol.13 , pp. 869-874
    • Boivin, A.J.1    Momparler, L.F.2    Hurtubise, A.3    Momparler, R.L.4
  • 10
    • 0037358032 scopus 로고    scopus 로고
    • Interaction of 5-aza-2′-deoxycytidine and depsipeptide on antineoplastic activity and activation of 14-3-3sigma, E-cadherin and tissue inhibitor of metalloproteinase 3 expression in human breast carcinoma cells
    • Gagnon J, Shaker S, Primeau M, Hurtubise A, and Momparler RL: Interaction of 5-aza-2′-deoxycytidine and depsipeptide on antineoplastic activity and activation of 14-3-3sigma, E-cadherin and tissue inhibitor of metalloproteinase 3 expression in human breast carcinoma cells. Anticancer Drugs 14, 193-202, 2003.
    • (2003) Anticancer Drugs , vol.14 , pp. 193-202
    • Gagnon, J.1    Shaker, S.2    Primeau, M.3    Hurtubise, A.4    Momparler, R.L.5
  • 11
    • 4644259264 scopus 로고    scopus 로고
    • Enhancement of xenograft tumor radiosensitivity by the histone deacetylase inhibitor MS-275 and correlation with histone hyperacetylation
    • Camphausen K, Scott T, Sproull M, and Tofilon PJ: Enhancement of xenograft tumor radiosensitivity by the histone deacetylase inhibitor MS-275 and correlation with histone hyperacetylation. Clin Cancer Res 10, 6066-6071, 2004.
    • (2004) Clin Cancer Res , vol.10 , pp. 6066-6071
    • Camphausen, K.1    Scott, T.2    Sproull, M.3    Tofilon, P.J.4
  • 13
    • 2542523228 scopus 로고    scopus 로고
    • Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors
    • Pei XY, Dai Y, and Grant S: Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors. Clin Cancer Res 10, 3839-3852, 2004.
    • (2004) Clin Cancer Res , vol.10 , pp. 3839-3852
    • Pei, X.Y.1    Dai, Y.2    Grant, S.3
  • 14
    • 31544436888 scopus 로고    scopus 로고
    • Dietary HDAC inhibitors: Time to rethink weak ligands in cancer chemoprevention?
    • Dashwood RH, Myzak MC, and Ho E: Dietary HDAC inhibitors: time to rethink weak ligands in cancer chemoprevention? Carcinogenesis 27, 344-349, 2006.
    • (2006) Carcinogenesis , vol.27 , pp. 344-349
    • Dashwood, R.H.1    Myzak, M.C.2    Ho, E.3
  • 15
    • 33645825587 scopus 로고    scopus 로고
    • Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice
    • Myzak MC, Dashwood WM, Orner GA, Ho E, and Dashwood RH: Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice. FASEB J 20, 506-508, 2006.
    • (2006) FASEB J , vol.20 , pp. 506-508
    • Myzak, M.C.1    Dashwood, W.M.2    Orner, G.A.3    Ho, E.4    Dashwood, R.H.5
  • 16
    • 0036252352 scopus 로고    scopus 로고
    • The effects of short-chain fatty acids on human colon cancer cell phenotype are associated with histone hyperacetylation
    • Hinnebusch BF, Meng S, Wu JT, Archer SY, and Hodin RA: The effects of short-chain fatty acids on human colon cancer cell phenotype are associated with histone hyperacetylation. J Nutr 132, 1012-1017, 2002.
    • (2002) J Nutr , vol.132 , pp. 1012-1017
    • Hinnebusch, B.F.1    Meng, S.2    Wu, J.T.3    Archer, S.Y.4    Hodin, R.A.5
  • 17
    • 0026495376 scopus 로고
    • Modulation of colonic epithelial cell proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats
    • Boffa LC, Lupton JR, Mariani MR, Ceppi M, Newmark HL, et al.: Modulation of colonic epithelial cell proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats. Cancer Res 52, 5906-5912, 1992.
    • (1992) Cancer Res , vol.52 , pp. 5906-5912
    • Boffa, L.C.1    Lupton, J.R.2    Mariani, M.R.3    Ceppi, M.4    Newmark, H.L.5
  • 18
    • 0017864644 scopus 로고
    • The effect of sodium butyrate on histone modification
    • Sealy L and Chalkley R: The effect of sodium butyrate on histone modification. Cell 14, 115-121, 1978.
    • (1978) Cell , vol.14 , pp. 115-121
    • Sealy, L.1    Chalkley, R.2
  • 19
    • 0028286187 scopus 로고
    • Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines
    • Heerdt BG, Houston MA, and Augenlicht LH: Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines. Cancer Res 54, 3288-3293, 1994.
    • (1994) Cancer Res , vol.54 , pp. 3288-3293
    • Heerdt, B.G.1    Houston, M.A.2    Augenlicht, L.H.3
  • 20
    • 0034662614 scopus 로고    scopus 로고
    • Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: Comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer
    • Mariadason JM, Corner GA, and Augenlicht LH: Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer. Cancer Res 60, 4561-4572, 2000.
    • (2000) Cancer Res , vol.60 , pp. 4561-4572
    • Mariadason, J.M.1    Corner, G.A.2    Augenlicht, L.H.3
  • 22
    • 0021163443 scopus 로고
    • Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate
    • Augeron C and Laboisse CL: Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate. Cancer Res 44, 3961-3969, 1984.
    • (1984) Cancer Res , vol.44 , pp. 3961-3969
    • Augeron, C.1    Laboisse, C.L.2
  • 23
    • 33646848610 scopus 로고    scopus 로고
    • The European Prospective Investigation into Cancer and Nutrition (EPIC)
    • Gonzalez CA: The European Prospective Investigation into Cancer and Nutrition (EPIC). Public Health Nutr 9, 124-126, 2006.
    • (2006) Public Health Nutr , vol.9 , pp. 124-126
    • Gonzalez, C.A.1
  • 24
    • 0034878394 scopus 로고    scopus 로고
    • Implementation of a 4-y, high-fiber, high-fruit-and-vegetable, low-fat dietary intervention: Results of dietary changes in the Polyp Prevention Trial
    • Lanza E, Schatzkin A, Daston C, Corle D, Freedman L, et al.: Implementation of a 4-y, high-fiber, high-fruit-and-vegetable, low-fat dietary intervention: results of dietary changes in the Polyp Prevention Trial. Am J Clin Nutr 74, 387-401, 2001.
    • (2001) Am J Clin Nutr , vol.74 , pp. 387-401
    • Lanza, E.1    Schatzkin, A.2    Daston, C.3    Corle, D.4    Freedman, L.5
  • 25
    • 34548844719 scopus 로고    scopus 로고
    • The polyp prevention trial continued follow-up study: No effect of a low-fat, high-fiber, high-fruit, and -vegetable diet on adenoma recurrence eight years after randomization
    • Lanza E, Yu B, Murphy G, Albert PS, Caan B, et al.: The polyp prevention trial continued follow-up study: no effect of a low-fat, high-fiber, high-fruit, and -vegetable diet on adenoma recurrence eight years after randomization. Cancer Epidemiol Biomarkers Prev 16, 1745-1752, 2007.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 1745-1752
    • Lanza, E.1    Yu, B.2    Murphy, G.3    Albert, P.S.4    Caan, B.5
  • 26
    • 20444369903 scopus 로고    scopus 로고
    • Diet and cancer: The disconnect between epidemiology and randomized clinical trials
    • Meyskens FL Jr and Szabo E: Diet and cancer: the disconnect between epidemiology and randomized clinical trials. Cancer Epidemiol Biomarkers Prev 14, 1366-1369, 2005.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 1366-1369
    • Meyskens Jr, F.L.1    Szabo, E.2
  • 27
    • 9744222928 scopus 로고    scopus 로고
    • Potential synergy of phytochemicals in cancer prevention: Mechanism of action
    • Liu RH: Potential synergy of phytochemicals in cancer prevention: mechanism of action. J Nutr 134, 3479S-3485S, 2004.
    • (2004) J Nutr , vol.134
    • Liu, R.H.1
  • 28
    • 33846675306 scopus 로고    scopus 로고
    • Combinations of tomato and broccoli enhance antitumor activity in dunning r3327-h prostate adenocarcinomas
    • Canene-Adams K, Lindshield BL, Wang S, Jeffery EH, Clinton SK, et al.: Combinations of tomato and broccoli enhance antitumor activity in dunning r3327-h prostate adenocarcinomas. Cancer Res 67, 836-843, 2007.
    • (2007) Cancer Res , vol.67 , pp. 836-843
    • Canene-Adams, K.1    Lindshield, B.L.2    Wang, S.3    Jeffery, E.H.4    Clinton, S.K.5
  • 29
    • 35848960778 scopus 로고    scopus 로고
    • Adherence to the USDA Food Guide, DASH Eating Plan, and Mediterranean dietary pattern reduces risk of colorectal adenoma
    • Dixon LB, Subar AF, Peters U, Weissfeld JL, Bresalier RS, et al.: Adherence to the USDA Food Guide, DASH Eating Plan, and Mediterranean dietary pattern reduces risk of colorectal adenoma. J Nutr 137, 2443-2450, 2007.
    • (2007) J Nutr , vol.137 , pp. 2443-2450
    • Dixon, L.B.1    Subar, A.F.2    Peters, U.3    Weissfeld, J.L.4    Bresalier, R.S.5
  • 30
    • 0036848492 scopus 로고    scopus 로고
    • Fish oil increases mitochondrial phospholipid unsaturation, upregulating reactive oxygen species and apoptosis in rat colonocytes
    • Hong MY, Chapkin RS, Barhoumi R, Burghardt RC, Turner ND, et al.: Fish oil increases mitochondrial phospholipid unsaturation, upregulating reactive oxygen species and apoptosis in rat colonocytes. Carcinogenesis 23, 1919-1925, 2002.
    • (2002) Carcinogenesis , vol.23 , pp. 1919-1925
    • Hong, M.Y.1    Chapkin, R.S.2    Barhoumi, R.3    Burghardt, R.C.4    Turner, N.D.5
  • 31
    • 27744544858 scopus 로고    scopus 로고
    • The role of docosahexaenoic acid in mediating mitochondrial membrane lipid oxidation and apoptosis in colonocytes
    • Ng Y, Barhoumi R, Tjalkens RB, Fan YY, Kolar S, et al.: The role of docosahexaenoic acid in mediating mitochondrial membrane lipid oxidation and apoptosis in colonocytes. Carcinogenesis 26, 1914-1921, 2005.
    • (2005) Carcinogenesis , vol.26 , pp. 1914-1921
    • Ng, Y.1    Barhoumi, R.2    Tjalkens, R.B.3    Fan, Y.Y.4    Kolar, S.5
  • 32
    • 0037409182 scopus 로고    scopus 로고
    • The molecular pathogenesis of acute promyelocytic leukaemia: Implications for the clinical management of the disease
    • Mistry AR, Pedersen EW, Solomon E, and Grimwade D: The molecular pathogenesis of acute promyelocytic leukaemia: implications for the clinical management of the disease. Blood Rev 17, 71-97, 2003.
    • (2003) Blood Rev , vol.17 , pp. 71-97
    • Mistry, A.R.1    Pedersen, E.W.2    Solomon, E.3    Grimwade, D.4
  • 33
    • 0041589184 scopus 로고    scopus 로고
    • Induction of TIG3, a putative class II tumor suppressor gene, by retinoic acid in head and neck and lung carcinoma cells and its association with suppression of the transformed phenotype
    • Higuchi E, Chandraratna RA, Hong WK, and Lotan R: Induction of TIG3, a putative class II tumor suppressor gene, by retinoic acid in head and neck and lung carcinoma cells and its association with suppression of the transformed phenotype. Oncogene 22, 4627-4635, 2003.
    • (2003) Oncogene , vol.22 , pp. 4627-4635
    • Higuchi, E.1    Chandraratna, R.A.2    Hong, W.K.3    Lotan, R.4
  • 34
    • 0027376609 scopus 로고
    • Retinoids in chemoprevention of head and neck carcinogenesis
    • Lippman SM, Benner SE, and Hong WK: Retinoids in chemoprevention of head and neck carcinogenesis. Prev Med 22, 693-700, 1993.
    • (1993) Prev Med , vol.22 , pp. 693-700
    • Lippman, S.M.1    Benner, S.E.2    Hong, W.K.3
  • 35
    • 3142594438 scopus 로고    scopus 로고
    • Methylation and regulation of expression of different retinoic acid receptor beta isoforms in human colon cancer
    • Youssef EM, Estecio MR, and Issa JP: Methylation and regulation of expression of different retinoic acid receptor beta isoforms in human colon cancer. Cancer Biol Ther 3, 82-86, 2004.
    • (2004) Cancer Biol Ther , vol.3 , pp. 82-86
    • Youssef, E.M.1    Estecio, M.R.2    Issa, J.P.3
  • 36
    • 26444451123 scopus 로고    scopus 로고
    • Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy
    • Fang MZ, Chen D, Sun Y, Jin Z, Christman JK, et al.: Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy. Clin Cancer Res 11, 7033-7041, 2005.
    • (2005) Clin Cancer Res , vol.11 , pp. 7033-7041
    • Fang, M.Z.1    Chen, D.2    Sun, Y.3    Jin, Z.4    Christman, J.K.5
  • 37
    • 33748518853 scopus 로고    scopus 로고
    • Circumvention and reactivation of the p53 oncogene checkpoint in mouse colon tumors
    • Aizu W, Belinsky GS, Flynn C, Noonan EJ, Boes CC, et al.: Circumvention and reactivation of the p53 oncogene checkpoint in mouse colon tumors. Biochem Pharmacol 72, 981-991, 2006.
    • (2006) Biochem Pharmacol , vol.72 , pp. 981-991
    • Aizu, W.1    Belinsky, G.S.2    Flynn, C.3    Noonan, E.J.4    Boes, C.C.5
  • 38
    • 0037114689 scopus 로고    scopus 로고
    • IL-3-induced enhancement of retinoic acid receptor activity is mediated through Stat5, which physically associates with retinoic acid receptors in an IL-3-dependent manner
    • Si J and Collins SJ: IL-3-induced enhancement of retinoic acid receptor activity is mediated through Stat5, which physically associates with retinoic acid receptors in an IL-3-dependent manner. Blood 100, 4401-4409, 2002.
    • (2002) Blood , vol.100 , pp. 4401-4409
    • Si, J.1    Collins, S.J.2
  • 39
    • 18144381890 scopus 로고    scopus 로고
    • Cyclooxygenase-2 regulation in colon cancer cells: Modulation of RNA polymerase II elongation by histone deacetylase inhibitors
    • Tong X, Yin L, Joshi S, Rosenberg DW, and Giardina C: Cyclooxygenase-2 regulation in colon cancer cells: modulation of RNA polymerase II elongation by histone deacetylase inhibitors. J Biol Chem 280, 15503-15509, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 15503-15509
    • Tong, X.1    Yin, L.2    Joshi, S.3    Rosenberg, D.W.4    Giardina, C.5
  • 40
    • 0036856355 scopus 로고    scopus 로고
    • MethPrimer: Designing primers for methylation PCRs
    • Li LC and Dahiya R: MethPrimer: designing primers for methylation PCRs. Bioinformatics 18, 1427-1431, 2002.
    • (2002) Bioinformatics , vol.18 , pp. 1427-1431
    • Li, L.C.1    Dahiya, R.2
  • 41
    • 18844465619 scopus 로고    scopus 로고
    • Methylome profiling of cancer cells by amplification of inter-methylated sites (AIMS)
    • Frigola J, Ribas M, Risques RA, and Peinado MA: Methylome profiling of cancer cells by amplification of inter-methylated sites (AIMS). Nucleic Acids Res 30, e28, 2002.
    • (2002) Nucleic Acids Res , vol.30
    • Frigola, J.1    Ribas, M.2    Risques, R.A.3    Peinado, M.A.4
  • 42
    • 0345275879 scopus 로고    scopus 로고
    • Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines
    • Fang MZ, Wang Y, Ai N, Hou Z, Sun Y, et al.: Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res 63, 7563-7570, 2003.
    • (2003) Cancer Res , vol.63 , pp. 7563-7570
    • Fang, M.Z.1    Wang, Y.2    Ai, N.3    Hou, Z.4    Sun, Y.5
  • 43
    • 31544481927 scopus 로고    scopus 로고
    • Histone deacetylases as targets for dietary cancer preventive agents: Lessons learned with butyrate, diallyl disulfide, and sulforaphane
    • Myzak MC and Dashwood RH: Histone deacetylases as targets for dietary cancer preventive agents: lessons learned with butyrate, diallyl disulfide, and sulforaphane. Curr Drug Targets 7, 443-452, 2006.
    • (2006) Curr Drug Targets , vol.7 , pp. 443-452
    • Myzak, M.C.1    Dashwood, R.H.2
  • 44
    • 0026075361 scopus 로고
    • Selective high affinity retinoic acid receptor alpha or beta-gamma ligands
    • Delescluse C, Cavey MT, Martin B, Bernard BA, Reichert U, et al.: Selective high affinity retinoic acid receptor alpha or beta-gamma ligands. Mol Pharmacol 40, 556-562, 1991.
    • (1991) Mol Pharmacol , vol.40 , pp. 556-562
    • Delescluse, C.1    Cavey, M.T.2    Martin, B.3    Bernard, B.A.4    Reichert, U.5
  • 45
    • 0027129816 scopus 로고
    • Identification of synthetic retinoids with selectivity for human nuclear retinoic acid receptor gamma
    • Bernard BA, Bernardon JM, Delescluse C, Martin B, Lenoir MC, et al.: Identification of synthetic retinoids with selectivity for human nuclear retinoic acid receptor gamma. Biochem Biophys Res Commun 186, 977-983, 1992.
    • (1992) Biochem Biophys Res Commun , vol.186 , pp. 977-983
    • Bernard, B.A.1    Bernardon, J.M.2    Delescluse, C.3    Martin, B.4    Lenoir, M.C.5
  • 47
    • 33847047461 scopus 로고    scopus 로고
    • Epigenetics: A landscape takes shape
    • Goldberg AD, Allis CD, and Bernstein E: Epigenetics: a landscape takes shape. Cell 128, 635-638, 2007.
    • (2007) Cell , vol.128 , pp. 635-638
    • Goldberg, A.D.1    Allis, C.D.2    Bernstein, E.3
  • 48
    • 85047687069 scopus 로고    scopus 로고
    • Therapeutic implications of DNA methylation
    • Szyf M: Therapeutic implications of DNA methylation. Future Oncol 1, 125-135, 2005.
    • (2005) Future Oncol , vol.1 , pp. 125-135
    • Szyf, M.1
  • 49
    • 25844530426 scopus 로고    scopus 로고
    • Epigenetic changes in solid and hematopoietic tumors
    • Toyota M and Issa JP: Epigenetic changes in solid and hematopoietic tumors. Semin Oncol 32, 521-530, 2005.
    • (2005) Semin Oncol , vol.32 , pp. 521-530
    • Toyota, M.1    Issa, J.P.2
  • 50
    • 34547792388 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer: The DNA hypermethylome
    • Esteller M: Epigenetic gene silencing in cancer: the DNA hypermethylome. Hum Mol Genet 16 Spec No 1, R50-59, 2007.
    • (2007) Hum Mol Genet , vol.16 , Issue.SPEC 1
    • Esteller, M.1
  • 51
    • 34249683635 scopus 로고    scopus 로고
    • Cross-talk between aging and cancer: The epigenetic language
    • Fraga MF, Agrelo R, and Esteller M: Cross-talk between aging and cancer: the epigenetic language. Ann NY Acad Sci 1100, 60-74, 2007.
    • (2007) Ann NY Acad Sci , vol.1100 , pp. 60-74
    • Fraga, M.F.1    Agrelo, R.2    Esteller, M.3
  • 52
    • 0025092693 scopus 로고
    • Ulcerative colitis and colorectal cancer. A population-based study
    • Ekbom A, Helmick C, Zack M, and Adami HO: Ulcerative colitis and colorectal cancer. A population-based study. N Engl J Med 323, 1228-1233, 1990.
    • (1990) N Engl J Med , vol.323 , pp. 1228-1233
    • Ekbom, A.1    Helmick, C.2    Zack, M.3    Adami, H.O.4
  • 53
    • 0035328527 scopus 로고    scopus 로고
    • Accelerated age-related CpG island methylation in ulcerative colitis
    • Issa JP, Ahuja N, Toyota M, Bronner MP, and Brentnall TA: Accelerated age-related CpG island methylation in ulcerative colitis. Cancer Res 61, 3573-3577, 2001.
    • (2001) Cancer Res , vol.61 , pp. 3573-3577
    • Issa, J.P.1    Ahuja, N.2    Toyota, M.3    Bronner, M.P.4    Brentnall, T.A.5
  • 54
    • 33845969839 scopus 로고    scopus 로고
    • Dietary polyphenols may affect DNA methylation
    • Fang M, Chen D, and Yang CS: Dietary polyphenols may affect DNA methylation. J Nutr 137, 223S-228S, 2007.
    • (2007) J Nutr , vol.137
    • Fang, M.1    Chen, D.2    Yang, C.S.3
  • 55
    • 31544473457 scopus 로고    scopus 로고
    • Upregulation of 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase by butyrate in Caco-2 cells
    • Schroder O, Turak S, Daniel C, Gaschott T, and Stein J: Upregulation of 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase by butyrate in Caco-2 cells. World J Gastroenterol 11, 7136-7141, 2005.
    • (2005) World J Gastroenterol , vol.11 , pp. 7136-7141
    • Schroder, O.1    Turak, S.2    Daniel, C.3    Gaschott, T.4    Stein, J.5
  • 56
    • 34047170360 scopus 로고    scopus 로고
    • Valproate induces widespread epigenetic reprogramming which involves demethylation of specific genes
    • Milutinovic S, D'Alessio AC, Detich N, and Szyf M: Valproate induces widespread epigenetic reprogramming which involves demethylation of specific genes. Carcinogenesis 28, 560-571, 2007.
    • (2007) Carcinogenesis , vol.28 , pp. 560-571
    • Milutinovic, S.1    D'Alessio, A.C.2    Detich, N.3    Szyf, M.4
  • 57
    • 33947368681 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor Trichostatin A induces global and gene-specific DNA demethylation in human cancer cell lines
    • Ou JN, Torrisani J, Unterberger A, Provencal N, Shikimi K, et al.: Histone deacetylase inhibitor Trichostatin A induces global and gene-specific DNA demethylation in human cancer cell lines. Biochem Pharmacol 73, 1297-1307, 2007.
    • (2007) Biochem Pharmacol , vol.73 , pp. 1297-1307
    • Ou, J.N.1    Torrisani, J.2    Unterberger, A.3    Provencal, N.4    Shikimi, K.5
  • 58
    • 34248370579 scopus 로고    scopus 로고
    • Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promoters
    • Dong E, Guidotti A, Grayson DR, and Costa E: Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promoters. Proc Natl Acad Sci USA 104, 4676-4681, 2007.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 4676-4681
    • Dong, E.1    Guidotti, A.2    Grayson, D.R.3    Costa, E.4
  • 59
    • 20944436158 scopus 로고    scopus 로고
    • Epigenetic modulation of retinoic acid receptor beta2 by the histone deacetylase inhibitor MS-275 in human renal cell carcinoma
    • Wang XF, Qian DZ, Ren M, Kato Y, Wei Y, et al.: Epigenetic modulation of retinoic acid receptor beta2 by the histone deacetylase inhibitor MS-275 in human renal cell carcinoma. Clin Cancer Res 11, 3535-3542, 2005.
    • (2005) Clin Cancer Res , vol.11 , pp. 3535-3542
    • Wang, X.F.1    Qian, D.Z.2    Ren, M.3    Kato, Y.4    Wei, Y.5
  • 60
    • 0033580326 scopus 로고    scopus 로고
    • A mammalian protein with specific demethylase activity for mCpG DNA
    • Bhattacharya SK, Ramchandani S, Cervoni N, and Szyf M: A mammalian protein with specific demethylase activity for mCpG DNA. Nature 397, 579-583, 1999.
    • (1999) Nature , vol.397 , pp. 579-583
    • Bhattacharya, S.K.1    Ramchandani, S.2    Cervoni, N.3    Szyf, M.4
  • 61
    • 0033580166 scopus 로고    scopus 로고
    • Gene expression: The amazing demethylase
    • Cedar H and Verdine GL: Gene expression: the amazing demethylase. Nature 397, 568-569, 1999.
    • (1999) Nature , vol.397 , pp. 568-569
    • Cedar, H.1    Verdine, G.L.2
  • 63
    • 0034623007 scopus 로고    scopus 로고
    • Gilbert's conjecture: The search for DNA (cytosine-5) demethylases and the emergence of new functions for eukaryotic DNA (cytosine-5) methyltransferases
    • Smith SS: Gilbert's conjecture: the search for DNA (cytosine-5) demethylases and the emergence of new functions for eukaryotic DNA (cytosine-5) methyltransferases. J Mol Biol 302, 1-7, 2000.
    • (2000) J Mol Biol , vol.302 , pp. 1-7
    • Smith, S.S.1
  • 64
    • 0019905063 scopus 로고    scopus 로고
    • Gjerset RA and Martin DWJr: Presence of a DNA demethylating activity in the nucleus of murine erythroleukemic cells. J Biol Chem257, 8581-8583, 1982.
    • Gjerset RA and Martin DWJr: Presence of a DNA demethylating activity in the nucleus of murine erythroleukemic cells. J Biol Chem257, 8581-8583, 1982.
  • 65
    • 0345676675 scopus 로고
    • Replacement of 5-methylcytosine by cytosine: A possible mechanism for transient DNA demethylation during differentiation
    • Razin A, Szyf M, Kafri T, Roll M, Giloh H, et al.: Replacement of 5-methylcytosine by cytosine: a possible mechanism for transient DNA demethylation during differentiation. Proc Natl Acad Sci USA 83, 2827-2831, 1986.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 2827-2831
    • Razin, A.1    Szyf, M.2    Kafri, T.3    Roll, M.4    Giloh, H.5
  • 67
    • 0033575886 scopus 로고    scopus 로고
    • The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
    • Hendrich B, Hardeland U, Ng HH, Jiricny J, and Bird A: The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites. Nature 401, 301-304, 1999.
    • (1999) Nature , vol.401 , pp. 301-304
    • Hendrich, B.1    Hardeland, U.2    Ng, H.H.3    Jiricny, J.4    Bird, A.5
  • 68
    • 0038527642 scopus 로고    scopus 로고
    • Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor
    • Di Croce L, Raker VA, Corsaro M, Fazi F, Fanelli M, et al.: Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science 295, 1079-1082, 2002.
    • (2002) Science , vol.295 , pp. 1079-1082
    • Di Croce, L.1    Raker, V.A.2    Corsaro, M.3    Fazi, F.4    Fanelli, M.5
  • 69
    • 33749173319 scopus 로고    scopus 로고
    • Folate: A magic bullet or a double edged sword for colorectal cancer prevention?
    • Kim YI: Folate: a magic bullet or a double edged sword for colorectal cancer prevention? Gut 55, 1387-1389, 2006.
    • (2006) Gut , vol.55 , pp. 1387-1389
    • Kim, Y.I.1
  • 70
    • 31544467532 scopus 로고    scopus 로고
    • Nutritional epigenetics: Impact of folate deficiency on DNA methylation and colon cancer susceptibility
    • Kim YI: Nutritional epigenetics: impact of folate deficiency on DNA methylation and colon cancer susceptibility. J Nutr 135, 2703-2709, 2005.
    • (2005) J Nutr , vol.135 , pp. 2703-2709
    • Kim, Y.I.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.