Long-chain n-3 polyunsaturated fatty acid from fish oil modulates aortic nitric oxide and tocopherol status in the rat

British Journal of Nutrition

Volumn 100, Issue 4, 2008, Pages 767-775

  López, Diego ^a   Möller, Matías ^b   Denicola, Ana ^b   Casós, Kelly ^a   Rubbo, Homero ^c   Ruiz Sanz, José Ignacio ^d   Mitjavila, Maria Teresa ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^c DEPARTAMENTO DE BIOQUÍMICA   (Uruguay)

^d UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Tocopherol; Aorta; Nitric oxide; Paraoxonase 1; Polyunsaturated fatty acids

Indexed keywords

ALPHA TOCOPHEROL; CORN OIL; LOW DENSITY LIPOPROTEIN; MENHADEN OIL; NITRIC OXIDE; OMEGA 3 FATTY ACID; THIOBARBITURIC ACID REACTIVE SUBSTANCE; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AORTA ATHEROSCLEROSIS; ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; DIET SUPPLEMENTATION; ELECTROPHORESIS; EX VIVO STUDY; HEART PROTECTION; IN VIVO STUDY; LIPID OXIDATION; MALE; NONHUMAN; RAT;

ALPHA-TOCOPHEROL; ANIMALS; AORTA; ATHEROSCLEROSIS; DIFFUSION; FATTY ACIDS, OMEGA-3; FISH OILS; LIPID PEROXIDATION; LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL; MALE; NITRIC OXIDE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; THIOBARBITURIC ACID REACTIVE SUBSTANCES; VITAMINS;

RATTUS; ZEA MAYS;

EID: 51749125081     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114508939854     Document Type: Article

References (46)

1. Chisolm GM & Steinberg D (2000) The oxidative modification hypothesis of atherogenesis: An overview. Free Radic Biol Med 28, 1815-1826.
2. Rubbo H, Radi R, Trujillo M, Telleri R, Kalyanaraman B, Barnes S, Kirk M & Freeman BA (1994) Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives. J Biol Chem 269 26066-26075.
3. Botti H, Batthyany C, Trostchansky A, Radi R, Freeman BA & Rubbo H (2004) Peroxynitrite-mediated α-tocopherol oxidation in low-density lipoprotein: A mechanistic approach. Free Radic Biol Med 36, 152-162.
4. O'Donnell VB, Chumley PH, Hogg N, Bloodsworth A, Darley-Usmar VM & Freeman BA (1997) Nitric oxide inhibition of lipid peroxidation: kinetics of reaction with lipid peroxyl radicals and comparison with α-tocopherol. Biochemistry 36, 15216-15223.
5. Denicola A, Batthyany C, Lissi E, Freeman BA, Rubbo H & Radi R (2002) Diffusion of nitric oxide into low density lipoprotein. J Biol Chem 277, 932-936.
6. Trostchansky A, Batthyany C, Botti H, Radi R, Denicola A & Rubbo H (2001) Formation of lipid-protein adducts in low-density lipoproteins by fluxes of peroxynitrite and its inhibition by nitric oxide. Arch Biochem Biophys 395, 225-232.
7. Aviram M, Hardak E, Vaya J, Mahmood S, Milo S, Hoffman A, Billicke S, Draganov D & Rosenblat M (2000) Human serum paraoxonase (PON1) Q and R selectively decrease lipid peroxides in human coronary and carotid atherosclerotic lesions: PON1 esterase and peroxidase-like activities. Circulation 101, 2510-2517.
8. Calder PC (2004) n-3 Fatty acids and cardiovascular disease: evidence explained and mechanisms explored. Clin Sci 107, 1-11.
9. Connor SL & Connor WE (1997) Are fish oils beneficial in the prevention and treatment of coronary artery disease? Am J Clin Nutr 66, 1020S-1031S.
10. Tagawa H, Shimokawa H, Tagawa T, Kuroiwa-Matsumoto M, Hirooka Y & Takeshita A (1999) Long-term treatment with eicosapentanoic acid augments both nitric oxide-mediated and non-nitric oxide-mediated endothelium-dependent forearm vasodilatation in patients with coronary artery disease. J Cardiovasc Pharmacol 33, 633-640.
11. López D, Caballero C, Sánchez J, Puig-Parellada P & Mitjavila MT (2001) Free radical production in aortic rings from rats fed a fish oil-rich diet. Am J Physiol Heart Circ Physiol 280, 2929-2935.
12. López D, Orta X, Casós K, Sáiz MP, Puig-Parellada P, Farriol M & Mitjavila MT (2004) Upregulation of endothelial nitric oxide synthase in rat aorta after ingestion of fish oil-rich diet. Am J Physiol Heart Circ Physiol 287, H567-H572.
13. Okuyama H, Kobayashi T & Watanabe S (1996) Dietary fatty acids - the n-6/n-3 balance and chronic elderly diseases. Excess linoleic acid and relative n-3 deficiency syndrome seen in Japan. Prog Lipid Res 35, 409-457.
14. Higdon JV, Du SH, Lee YS, Wu T & Wander RC (2001) Supplementation of postmenopausal women with fish oil does not increase overall oxidation of LDL ex vivo compared to dietary oils rich in oleate and linoleate. J Lipid Res 42, 407-418.
15. Moreno JJ & Mitjavila MT (2003) The degree of unsaturation of dietary fatty acids and the development of atherosclerosis. J Nutr Biochem 14, 182-195.
16. Wander RC, Du SH, Ketchum SO & Rowe KE (1996) Effects of interaction of RRR-tocopheryl acetate and fish oil on low-density-lipoprotein oxidation in postmenopausal women with and without hormone-replacement therapy. Am J Clin Nutr 63, 184-193.
17. Fischkoff S & Vanderkooi JM (1975) Oxygen diffusion in biological and artificial membranes determined by the fluorochrome pyrene. J Gen Physiol 65, 663-676.
18. Lepage G & Roy CC (1986) Direct transesterification of all classes of lipids in a one-step reaction. J Lipid Res 27, 114-120.
19. Ruiz-Sanz JI, Navarro R, Martinez R, Martin C, Lacort M, Matorras R & Ruiz-Larrea MB (2001) 17β-Estradiol affects in vivo the low density lipoprotein composition, particle size, and oxidizability. Free Radic Biol Med 31, 391-397.
20. Ha YC & Barter PJ (1985) Rapid separation of plasma lipoproteins by gel permeation chromatography on agarose gel Superose 6B. J Chromatogr 341, 154-159.
21. Esterbauer H, Gebicki J, Puhl H & Jürgens G (1992) The role of lipid peroxidation and antioxidants in oxidative modification of LDL. Free Radic Biol Med 13, 341-390.
22. Vanin AF (1999) Iron diethyldithiocarbamate as spin trap for nitric oxide detection. Methods Enzymol 301, 269-279.
23. Yagi K (1984) Assay for blood plasma or serum. Methods Enzymol 105, 328-331.
24. Beltowski J, Wójcicka G & Marciniak A (2002) Species- and substrate-specific stimulation of human plasma paraoxonase 1 (PON1) activity by high chloride concentration. Acta Biochim Pol 49 927-936.
25. Shapiro SS, Mott DJ & Machlin LJ (1984) Kinetic characteristics of β-carotene uptake and depletion in rat tissue. J Nutr 114, 1924-1933.
26. Carbonneau MA, Cartron E, Léger CL, Senglat C & Descomps B (2002) New insight on the relationship between LDL composition, associated proteins, oxidative resistance and preparation procedure. Free Radic Res 36, 127-142.
27. Mesa MD, Buckley R, Minihane AM & Yaqoob P (2004) Effects of oils rich in eicosapentaenoic and docosahexaenoic acids on the oxidizability and thrombogenicity of low-density lipoprotein. Atherosclerosis 175 333-343.
28. Liochev SI & Fridovich I (2002) Superoxide and nitric oxide: consequences of varying rates of production and consumption: A theoretical treatment. Free Radic Biol Med 33, 137-141.
29. Piolot A, Blache D, Boulet L, Fortin LJ, Dubreuil D, Marcoux C, Davignon J & Lussier-Cacan S (2003) Effect of fish oil on LDL oxidation and plasma homocysteine concentration in health. J Lab Clin Med 141 41-49.
30. Harris WS, Rambjør GS, Windsor SL & Diederich D (1997) n-3 Fatty acids and urinary excretion of nitric oxide metabolites in humans. Am J Clin Nutr 65, 459-464.
31. Erdogan H, Fadillioglu E, Ozgocmen S, Sogut S, Ozyurt B, Akyol O & Ardicoglu O (2004) Effect of fish oil supplementation on plasma oxidant/ antioxidant status in rats. Prostaglandins Leukot Essent Fatty Acids 71, 149-152.
32. Denicola A, Souza JM, Radi R & Lissi E (1996) Nitric oxide diffusion in membranes determined by fluorescence quenching. Arch Biochem Biophys 328, 208-212.
33. Schopfer FJ, Baker PRS, Giles G, et al. (2005) Fatty acid transduction of nitric oxide signaling. Nitrolinoleic acid is a hydrophobically stabilized nitric oxide donor. J Biol Chem 280 19289-19297.
34. Cui T, Schopfer FJ, Zhang J, et al. (2006) Nitrated fatty acids: endogenous anti-inflammatory signaling mediators. J Biol Chem 281, 35686-35698.
35. Heller R, Werner-Felmayer G & Werner ER (2004) α-Tocopherol and endothelial nitric oxide synthesis. Ann N Y Acad Sci 1031, 74-85.
36. Thomas MJ, Thornburg T, Manning J, Hooper K & Rudel LL (1994) Fatty acid composition of low-density lipoprotein influences its susceptibility to autoxidation. Biochemistry 33, 1828-1834.
37. Childs MT, King IB & Knopp RH (1990) Divergent lipoprotein responses to fish oils with various ratios of eicosapentaenoic acid and docosahexaenoic acid. Am J Clin Nutr 52, 632-639.
38. Bjørneboe A, Bjørneboe GE & Drevon CA (1990) Absorption, transport and distribution of vitamin E. J Nutr 120, 233-242.
39. Napolitano M, Bravo E, Avella M, Chico Y, Ochoa B, Botham KM & Rivabene R (2004) The fatty acid composition of chylomicron remnants influences their propensity to oxidate. Nutr Metab Cardiovasc Dis 14, 241-247.
40. Bonanome A, Pagnan A, Biffanti S, Opportuno A, Sorgato F, Dorella M, Maiorino M & Ursini F (1992) Effect of dietary monounsaturated and polyunsaturated fatty acids on the susceptibility of plasma low density lipoproteins to oxidative modification. Arterioscler Thromb Vasc Biol 12, 529-533.
41. Sorensen NS, Marckmann P, Hoy CE, van Duyvenvoorde W & Princen HM (1998) Effect of fish-oil-enriched margarine on plasma lipids, low-density-lipoprotein particle composition, size, and susceptibility to oxidation. Am J Clin Nutr 68, 235-241.
42. Wander RC, Du SH & Thomas DR (1998) Influence of longchain polyunsaturated fatty acids on oxidation of low density lipoprotein. Prostaglandins Leukot Essent Fatty Acids 59, 143-151.
43. Brude IR, Drevon CA, Hjermann I, et al. (1997) Peroxidation of LDL from combined-hyperlipidemic male smokers supplied with omega-3 fatty acids and antioxidants. Arterioscler Thromb Vasc Biol 17, 2576-2588.
44. Higgins S, Carroll YL, McCarthy SN, Corridan BM, Roche HM, Wallace JM, O'Brien NM & Morrissey PA (2001) Susceptibility of LDL to oxidative modification in healthy volunteers supplemented with low doses of n 3 polyunsaturated fatty acids. Br J Nutr 85, 23-31.
45. Oostenburg GS, Mensink RP, Hardeman MR, De Vries T, Brouns F & Hornstra G (1997) Exercise performance, red blood cell deformability, and lipid peroxidation, effects of fish oil and vitamin E. J Appl Physiol 83, 746-752.
46. Leigh-Firbank EC, Minihane AM, Leake DS, Wright JW, Murphy MC, Griffin BA & Williams CM (2002) Eicosapentaenoic acid and docosahexaenoic acid from fish oils: Differential associations with lipid responses. Br J Nutr 87, 435-445.