Mitochondrial localization of human frataxin is necessary but processing is not for rescuing frataxin deficiency in Trypanosoma brucei

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 36, 2008, Pages 13468-13473

  Long, Shaojun ^a,b   Jirků, Milan ^a,b   Ayala, Francisco J ^c   Lukeš, Julius ^a,b  

^a INSTITUTE OF PARASITOLOGY   (Czech Republic)

^b UNIVERSITY OF SOUTH BOHEMIA   (Czech Republic)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Evolutionary conservation; Function rescue; Import; Kinetoplastida; Mitochondria protein processing

Indexed keywords

FRATAXIN; SIGNAL PEPTIDE;

ARTICLE; DOWN REGULATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; MITOCHONDRION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN TRANSPORT; TRYPANOSOMA; TRYPANOSOMA BRUCEI;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL LINE; CYTOSOL; HUMANS; IRON-BINDING PROTEINS; IRON-SULFUR PROTEINS; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; TRYPANOSOMA BRUCEI BRUCEI;

EXCAVATA; KINETOPLASTIDA; TRYPANOSOMA BRUCEI;

EID: 51649086651     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0806762105     Document Type: Article

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