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Volumn 7, Issue 7, 2008, Pages 937-949

Melanoma vaccines

Author keywords

Adjuvant; Antigen; Cytokine; Dendritic cell; Melanoma; Peptide; Vaccine

Indexed keywords

ALLOVECTIN 7; ALVAC MINIMAGE 1; ALVAC MINIMAGE 3; BCG VACCINE; BETA 2 MICROGLOBULIN; CANCER VACCINE; CYCLOPHOSPHAMIDE; DACARBAZINE; DETOX PC; GAMMA1B INTERFERON; GANGLIOSIDE GM2; GLYCOPROTEIN GP 100; GLYCOPROTEIN GP 75; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA B7 ANTIGEN; INTERFERON; INTERLEUKIN 2; KEYHOLE LIMPET HEMOCYANIN; M VAX; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MELACINE; MELAN A; MELANOMA ANTIGEN 1; MELANOMA VACCINE; MONOPHENOL MONOOXYGENASE; PEPTIDE VACCINE; PERFORIN; RAG2 PROTEIN; TOLL LIKE RECEPTOR; TUMOR ANTIGEN; TYROSINASE RELATED PROTEIN 1; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 51349156654     PISSN: 14760584     EISSN: 17448395     Source Type: Journal    
DOI: 10.1586/14760584.7.7.937     Document Type: Review
Times cited : (9)

References (92)
  • 1
    • 0028081705 scopus 로고
    • Coley's toxins, tumor necrosis factor and cancer research: A historical perspective
    • Wiemann B, Starnes CO. Coley's toxins, tumor necrosis factor and cancer research: a historical perspective. Pharmacol. Ther. 64(3), 529-564 (1994).
    • (1994) Pharmacol. Ther , vol.64 , Issue.3 , pp. 529-564
    • Wiemann, B.1    Starnes, C.O.2
  • 2
    • 0021249547 scopus 로고
    • Spontaneous regression of primary malignant melanoma with metastases
    • Kessler E, Schwartz P, Antebi E. Spontaneous regression of primary malignant melanoma with metastases. Plast. Reconstr. Surg. 74(3), 427-429 (1984).
    • (1984) Plast. Reconstr. Surg , vol.74 , Issue.3 , pp. 427-429
    • Kessler, E.1    Schwartz, P.2    Antebi, E.3
  • 3
    • 33748335363 scopus 로고    scopus 로고
    • Spontaneous regression of melanoma with distant metastases - report of a patient with brain metastases
    • Satzger I, Schenck F, Kapp A, Gutzmer R. Spontaneous regression of melanoma with distant metastases - report of a patient with brain metastases. Eur. J. Dermatol. 16(4), 454-455 (2006).
    • (2006) Eur. J. Dermatol , vol.16 , Issue.4 , pp. 454-455
    • Satzger, I.1    Schenck, F.2    Kapp, A.3    Gutzmer, R.4
  • 5
    • 51349149448 scopus 로고    scopus 로고
    • Cancer immunoediting: From immune surveillance to immune escape
    • Prendergast G, Jaffee E Eds, Elsevier, NY, USA
    • Kim R. Cancer immunoediting: from immune surveillance to immune escape. In: Cancer Immunotherapy: Immune Suppression and Tumor Growth. Prendergast G, Jaffee E (Eds). Elsevier, NY, USA 9-25 (2007).
    • (2007) Cancer Immunotherapy: Immune Suppression and Tumor Growth , pp. 9-25
    • Kim, R.1
  • 6
    • 37849014248 scopus 로고    scopus 로고
    • Toll-like receptors and immune regulation: Implications for cancer therapy
    • Wang RF, Miyahara Y, Wang HY. Toll-like receptors and immune regulation: implications for cancer therapy. Oncogene 27(2), 181-189 (2008).
    • (2008) Oncogene , vol.27 , Issue.2 , pp. 181-189
    • Wang, R.F.1    Miyahara, Y.2    Wang, H.Y.3
  • 7
    • 0032880649 scopus 로고    scopus 로고
    • Human tumor antigens for cancer vaccine development
    • Wang RF, Rosenberg SA. Human tumor antigens for cancer vaccine development. Immunol. Rev. 170, 85-100 (1999).
    • (1999) Immunol. Rev , vol.170 , pp. 85-100
    • Wang, R.F.1    Rosenberg, S.A.2
  • 8
    • 0016422950 scopus 로고
    • Clinical and immunological significance of human melanoma cytotoxic antibody
    • Bodurtha AJ, Chee DO, Laucius JF, Mastrangelo MJ, Prehn RT. Clinical and immunological significance of human melanoma cytotoxic antibody. Cancer Res. 35(1), 189-193 (1975).
    • (1975) Cancer Res , vol.35 , Issue.1 , pp. 189-193
    • Bodurtha, A.J.1    Chee, D.O.2    Laucius, J.F.3    Mastrangelo, M.J.4    Prehn, R.T.5
  • 9
    • 0035339880 scopus 로고    scopus 로고
    • Kirkwood JM, Ibrahim JG, Sosman JA et al. High-dose interferon α-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801. J. Clin. Oncol. 19(9), 2370-2380 (2001). • Important randomized trial comparing the standard high-dose IFN-α regimen to a vaccine in high-risk, surgically resected melanoma that showed the vaccine treatment was inferior.
    • Kirkwood JM, Ibrahim JG, Sosman JA et al. High-dose interferon α-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801. J. Clin. Oncol. 19(9), 2370-2380 (2001). • Important randomized trial comparing the standard high-dose IFN-α regimen to a vaccine in high-risk, surgically resected melanoma that showed the vaccine treatment was inferior.
  • 10
    • 0034659952 scopus 로고    scopus 로고
    • Analysis of therapeutic and immunologic effects of R(24) anti-GD3 monoclonal antibody in 37 patients with metastatic melanoma
    • Kirkwood JM, Mascari RA, Edington HD et al. Analysis of therapeutic and immunologic effects of R(24) anti-GD3 monoclonal antibody in 37 patients with metastatic melanoma. Cancer 88(12), 2693-2702 (2000).
    • (2000) Cancer , vol.88 , Issue.12 , pp. 2693-2702
    • Kirkwood, J.M.1    Mascari, R.A.2    Edington, H.D.3
  • 11
    • 0026785589 scopus 로고
    • Phase I trial of the murine monoclonal anti-GD2 antibody 14G2a in metastatic melanoma
    • Saleh MN, Khazaeli MB, Wheeler RH et al. Phase I trial of the murine monoclonal anti-GD2 antibody 14G2a in metastatic melanoma. Cancer Res. 52(16), 4342-4347 (1992).
    • (1992) Cancer Res , vol.52 , Issue.16 , pp. 4342-4347
    • Saleh, M.N.1    Khazaeli, M.B.2    Wheeler, R.H.3
  • 12
    • 0033764131 scopus 로고    scopus 로고
    • Recombinant antibodies against ganglioside expressed on tumor cells
    • Hanai N, Nakamura K, Shitara K. Recombinant antibodies against ganglioside expressed on tumor cells. Cancer Chemother. Pharmacol. 46(Suppl.) S13-S17 (2000).
    • (2000) Cancer Chemother. Pharmacol , vol.46 , Issue.SUPPL.
    • Hanai, N.1    Nakamura, K.2    Shitara, K.3
  • 13
    • 16544364126 scopus 로고    scopus 로고
    • Phase I clinical trial of the immunocytokine EMD 273063 in melanoma patients
    • King DM, Albertini MR, Schalch H et al. Phase I clinical trial of the immunocytokine EMD 273063 in melanoma patients. J. Clin. Oncol. 22(22), 4463-4473 (2004).
    • (2004) J. Clin. Oncol , vol.22 , Issue.22 , pp. 4463-4473
    • King, D.M.1    Albertini, M.R.2    Schalch, H.3
  • 14
    • 0035361342 scopus 로고    scopus 로고
    • Specific localization, g camera imaging, and intracellular trafficking of radiolabelled chimeric anti-G(D3) ganglioside monoclonal antibody KM871 in SK-MEL-28 melanoma xenografts
    • Lee FT, Rigopoulos A, Hall C et al. Specific localization, g camera imaging, and intracellular trafficking of radiolabelled chimeric anti-G(D3) ganglioside monoclonal antibody KM871 in SK-MEL-28 melanoma xenografts. Cancer Res. 61(11), 4474-4482 (2001).
    • (2001) Cancer Res , vol.61 , Issue.11 , pp. 4474-4482
    • Lee, F.T.1    Rigopoulos, A.2    Hall, C.3
  • 15
    • 34247891493 scopus 로고    scopus 로고
    • Construction and characterization of a high-affinity humanized SM5-1 monoclonal antibody
    • Li B, Wang H, Zhang D et al. Construction and characterization of a high-affinity humanized SM5-1 monoclonal antibody. Biochem. Biophys. Res. Commun. 357(4), 951-956 (2007).
    • (2007) Biochem. Biophys. Res. Commun , vol.357 , Issue.4 , pp. 951-956
    • Li, B.1    Wang, H.2    Zhang, D.3
  • 16
    • 33646179699 scopus 로고    scopus 로고
    • Human T cell responses against melanoma
    • Excellent review of T-cell immunoregulation in melanoma, •
    • Boon T, Coulie PG, Van den Eynde BJ, van der Bruggen P. Human T cell responses against melanoma. Annu. Rev. Immunol. 24, 175-208 (2006). • Excellent review of T-cell immunoregulation in melanoma.
    • (2006) Annu. Rev. Immunol , vol.24 , pp. 175-208
    • Boon, T.1    Coulie, P.G.2    Van den Eynde, B.J.3    van der Bruggen, P.4
  • 17
    • 34948832619 scopus 로고    scopus 로고
    • Melanoma cancer vaccines and anti-tumor T cell responses
    • Vujanovic L, Butterfield LH. Melanoma cancer vaccines and anti-tumor T cell responses. J. Cell. Biochem. 102(2), 301-310 (2007).
    • (2007) J. Cell. Biochem , vol.102 , Issue.2 , pp. 301-310
    • Vujanovic, L.1    Butterfield, L.H.2
  • 18
    • 0242366614 scopus 로고    scopus 로고
    • Mini-review: Regulation of cytotoxic T lymphocyte responses by dendritic cells: peaceful coexistence of cross-priming and direct priming?
    • Melief CJ. Mini-review: regulation of cytotoxic T lymphocyte responses by dendritic cells: peaceful coexistence of cross-priming and direct priming? Eur. J. Immunol. 33(10), 2645-2654 (2003).
    • (2003) Eur. J. Immunol , vol.33 , Issue.10 , pp. 2645-2654
    • Melief, C.J.1
  • 19
    • 0037435926 scopus 로고    scopus 로고
    • Mechanisms of vaccine adjuvant activity: Initiation and regulation of immune responses by vaccine adjuvants
    • Schijns VE. Mechanisms of vaccine adjuvant activity: initiation and regulation of immune responses by vaccine adjuvants. Vaccine 21(9-10), 829-831 (2003).
    • (2003) Vaccine , vol.21 , Issue.9-10 , pp. 829-831
    • Schijns, V.E.1
  • 20
    • 0028908324 scopus 로고
    • Paracrine cytokine adjuvants in cancer immunotherapy
    • Pardoll DM. Paracrine cytokine adjuvants in cancer immunotherapy. Annu. Rev. Immunol. 13, 399-415 (1995).
    • (1995) Annu. Rev. Immunol , vol.13 , pp. 399-415
    • Pardoll, D.M.1
  • 21
    • 0031863732 scopus 로고    scopus 로고
    • Use of cellular and cytokine adjuvants in the immunotherapy of cancer
    • Salgaller ML, Lodge PA. Use of cellular and cytokine adjuvants in the immunotherapy of cancer. J. Surg. Oncol. 68(2), 122-138 (1998).
    • (1998) J. Surg. Oncol , vol.68 , Issue.2 , pp. 122-138
    • Salgaller, M.L.1    Lodge, P.A.2
  • 22
    • 37849002321 scopus 로고    scopus 로고
    • Toll-like receptor 9 (TLR9) agonists in the treatment of cancer
    • Krieg AM. Toll-like receptor 9 (TLR9) agonists in the treatment of cancer. Oncogene 27(2), 161-167 (2008).
    • (2008) Oncogene , vol.27 , Issue.2 , pp. 161-167
    • Krieg, A.M.1
  • 23
    • 33747342457 scopus 로고    scopus 로고
    • Toll-like receptor 9 contributes to recognition of Mycobacterium bovis bacillus Calmette-Guerin by Flt3-ligand generated dendritic cells
    • von Meyenn F, Schaefer M, Weighardt H et al. Toll-like receptor 9 contributes to recognition of Mycobacterium bovis bacillus Calmette-Guerin by Flt3-ligand generated dendritic cells. Immunobiology 211(6-8), 557-565 (2006).
    • (2006) Immunobiology , vol.211 , Issue.6-8 , pp. 557-565
    • von Meyenn, F.1    Schaefer, M.2    Weighardt, H.3
  • 25
    • 0033998594 scopus 로고    scopus 로고
    • Adjuvant therapy of stage III and IV malignant melanoma using granulocyte-macrophage colony-stimulating factor
    • Spitler L, Grossbard M, Ernstoff M et al. Adjuvant therapy of stage III and IV malignant melanoma using granulocyte-macrophage colony-stimulating factor. J. Clin. Oncol. 18, 1614-1621 (2000).
    • (2000) J. Clin. Oncol , vol.18 , pp. 1614-1621
    • Spitler, L.1    Grossbard, M.2    Ernstoff, M.3
  • 26
    • 0033020036 scopus 로고    scopus 로고
    • Recombinant human granulocyte macrophage-colony stimulating factor (rhGM-CSF) and autologous melanoma vaccine mediate tumor regression in patients with metastatic melanoma
    • Leong SP, Enders-Zohr P, Zhou YM et al. Recombinant human granulocyte macrophage-colony stimulating factor (rhGM-CSF) and autologous melanoma vaccine mediate tumor regression in patients with metastatic melanoma. J. Immunother. 22(2), 166-174 (1999).
    • (1999) J. Immunother , vol.22 , Issue.2 , pp. 166-174
    • Leong, S.P.1    Enders-Zohr, P.2    Zhou, Y.M.3
  • 27
    • 0032828653 scopus 로고    scopus 로고
    • Complete molecular remissions induced by patient-specific vaccination plus granulocyte-monocyte colony-stimulating factor against lymphoma
    • Bendandi M, Gocke CD, Kobrin CB et al. Complete molecular remissions induced by patient-specific vaccination plus granulocyte-monocyte colony-stimulating factor against lymphoma. Nat. Med. 5(10), 1171-1177 (1999).
    • (1999) Nat. Med , vol.5 , Issue.10 , pp. 1171-1177
    • Bendandi, M.1    Gocke, C.D.2    Kobrin, C.B.3
  • 28
    • 85047698677 scopus 로고    scopus 로고
    • Prime-boost vaccines encoding an intracellular idiotype/GM-CSF fusion protein induce protective cell-mediated immunity in murine pre-B cell leukemia
    • Pasquini S, Peralta S, Missiaglia E, Carta L, Lemoine NR. Prime-boost vaccines encoding an intracellular idiotype/GM-CSF fusion protein induce protective cell-mediated immunity in murine pre-B cell leukemia. Gene Ther. 9(8), 503-510 (2002).
    • (2002) Gene Ther , vol.9 , Issue.8 , pp. 503-510
    • Pasquini, S.1    Peralta, S.2    Missiaglia, E.3    Carta, L.4    Lemoine, N.R.5
  • 29
    • 0032993163 scopus 로고    scopus 로고
    • Construction and characterization of a chimeric fusion protein consisting of an anti-idiotype antibody mimicking a breast cancer-associated antigen and the cytokine GM-CSF
    • Tripathi PK, Qin H, Bhattacharya-Chatterjee M, Ceriani RL, Foon KA, Chatterjee SK. Construction and characterization of a chimeric fusion protein consisting of an anti-idiotype antibody mimicking a breast cancer-associated antigen and the cytokine GM-CSF. Hybridoma 18(2), 193-202 (1999).
    • (1999) Hybridoma , vol.18 , Issue.2 , pp. 193-202
    • Tripathi, P.K.1    Qin, H.2    Bhattacharya-Chatterjee, M.3    Ceriani, R.L.4    Foon, K.A.5    Chatterjee, S.K.6
  • 30
    • 0037203899 scopus 로고    scopus 로고
    • Co-expression of granulocyte-macrophage colony-stimulating factor with antigen enhances humoral and tumor immunity after DNA vaccination
    • Sun X, Hodge LM, Jones HP, Tabor L, Simecka JW. Co-expression of granulocyte-macrophage colony-stimulating factor with antigen enhances humoral and tumor immunity after DNA vaccination. Vaccine 20(9-10), 1466-1474 (2002).
    • (2002) Vaccine , vol.20 , Issue.9-10 , pp. 1466-1474
    • Sun, X.1    Hodge, L.M.2    Jones, H.P.3    Tabor, L.4    Simecka, J.W.5
  • 31
    • 0001431323 scopus 로고
    • Granulocyte-macrophage colony stimulating factor
    • Thomson A Ed, Academic Press, San Diego, CA, USA
    • Rasko J, Gough N. Granulocyte-macrophage colony stimulating factor. In: The Cytokine Handbook. Thomson A (Ed.). Academic Press, San Diego, CA, USA 343-370 (1994).
    • (1994) The Cytokine Handbook , pp. 343-370
    • Rasko, J.1    Gough, N.2
  • 32
    • 0027538181 scopus 로고
    • Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
    • Dranoff G, Jaffee E, Lazenby A et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc. Natl Acad. Sci. USA 90(8), 3539-3543 (1993).
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , Issue.8 , pp. 3539-3543
    • Dranoff, G.1    Jaffee, E.2    Lazenby, A.3
  • 33
    • 34748909630 scopus 로고    scopus 로고
    • Enhancing cancer vaccines with immunomodulators
    • Berinstein NL. Enhancing cancer vaccines with immunomodulators. Vaccine 25 (Suppl. 2), B72-B88 (2007).
    • (2007) Vaccine , vol.25 , Issue.SUPPL. 2
    • Berinstein, N.L.1
  • 34
    • 34250821064 scopus 로고    scopus 로고
    • Overlapping human leukocyte antigen class I/II binding peptide vaccine for the treatment of patients with stage IV melanoma: Evidence of systemic immune dysfunction
    • Celis E. Overlapping human leukocyte antigen class I/II binding peptide vaccine for the treatment of patients with stage IV melanoma: evidence of systemic immune dysfunction. Cancer 110(1), 203-214 (2007).
    • (2007) Cancer , vol.110 , Issue.1 , pp. 203-214
    • Celis, E.1
  • 35
    • 33644813226 scopus 로고    scopus 로고
    • Immunogenicity, including vitiligo, and feasibility of vaccination with autologous GM-CSF-transduced tumor cells in metastatic melanoma patients
    • Luiten RM, Kueter EW, Mooi W et al. Immunogenicity, including vitiligo, and feasibility of vaccination with autologous GM-CSF-transduced tumor cells in metastatic melanoma patients. J. Clin. Oncol. 23(35), 8978-8991 (2005).
    • (2005) J. Clin. Oncol , vol.23 , Issue.35 , pp. 8978-8991
    • Luiten, R.M.1    Kueter, E.W.2    Mooi, W.3
  • 36
    • 33746802910 scopus 로고    scopus 로고
    • Peptide vaccination of patients with metastatic melanoma: Improved clinical outcome in patients demonstrating effective immunization
    • Markovic SN, Suman VJ, Ingle JN et al. Peptide vaccination of patients with metastatic melanoma: improved clinical outcome in patients demonstrating effective immunization. Am. J. Clin. Oncol. 29(4), 352-360 (2006).
    • (2006) Am. J. Clin. Oncol , vol.29 , Issue.4 , pp. 352-360
    • Markovic, S.N.1    Suman, V.J.2    Ingle, J.N.3
  • 37
    • 0036005890 scopus 로고    scopus 로고
    • Interleukin-12 in anti-tumor immunity and immunotherapy
    • Colombo MP, Trinchieri G. Interleukin-12 in anti-tumor immunity and immunotherapy. Cytokine Growth Factor Rev. 13(2), 155-168 (2002).
    • (2002) Cytokine Growth Factor Rev , vol.13 , Issue.2 , pp. 155-168
    • Colombo, M.P.1    Trinchieri, G.2
  • 38
    • 34548067624 scopus 로고    scopus 로고
    • Interleukin-12: Biological properties and clinical application
    • Del Vecchio M, Bajetta E, Canova S et al. Interleukin-12: biological properties and clinical application. Clin. Cancer Res. 13(16), 4677-4685 (2007).
    • (2007) Clin. Cancer Res , vol.13 , Issue.16 , pp. 4677-4685
    • Del Vecchio, M.1    Bajetta, E.2    Canova, S.3
  • 39
    • 41149108247 scopus 로고    scopus 로고
    • The role of vaccine therapy in the treatment of melanoma
    • Lens M. The role of vaccine therapy in the treatment of melanoma. Expert Opin. Biol. Ther. 8(3), 315-323 (2008).
    • (2008) Expert Opin. Biol. Ther , vol.8 , Issue.3 , pp. 315-323
    • Lens, M.1
  • 40
    • 34748849509 scopus 로고    scopus 로고
    • Vaccine therapy for melanoma: Current status and future directions
    • Terando AM, Faries MB, Morton DL. Vaccine therapy for melanoma: current status and future directions. Vaccine 25(Suppl. 2), B4-B16 (2007).
    • (2007) Vaccine , vol.25 , Issue.SUPPL. 2
    • Terando, A.M.1    Faries, M.B.2    Morton, D.L.3
  • 41
    • 34347210289 scopus 로고    scopus 로고
    • An update on malignant melanoma vaccine research: Insights into mechanisms for improving the design and potency of melanoma therapeutic vaccines
    • Ralph SJ. An update on malignant melanoma vaccine research: insights into mechanisms for improving the design and potency of melanoma therapeutic vaccines. Am. J. Clin. Dermatol. 8(3), 123-141 (2007).
    • (2007) Am. J. Clin. Dermatol , vol.8 , Issue.3 , pp. 123-141
    • Ralph, S.J.1
  • 43
    • 7444242049 scopus 로고    scopus 로고
    • M-Vax: An autologous, hapten-modified vaccine for human cancer
    • Berd D. M-Vax: an autologous, hapten-modified vaccine for human cancer. Expert Rev. Vaccines 3(5), 521-527 (2004).
    • (2004) Expert Rev. Vaccines , vol.3 , Issue.5 , pp. 521-527
    • Berd, D.1
  • 44
    • 39749186213 scopus 로고    scopus 로고
    • Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: The C-100-21 study group
    • Testori A, Richards J, Whitman E et al. Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: the C-100-21 study group. J. Clin. Oncol. 26(6), 955-962 (2008).
    • (2008) J. Clin. Oncol , vol.26 , Issue.6 , pp. 955-962
    • Testori, A.1    Richards, J.2    Whitman, E.3
  • 45
    • 34250851319 scopus 로고    scopus 로고
    • An international, randomized, double-blind, Phase 3 study of the specific active immunotherapy agent, onamelatucel-L (CanvaxinTM), compared with placebo as a post-surgical adjuvant in AJCC stage IV melanoma
    • Morton DL, Thompson JF, Kashani-Sabet M, Kelley M, Gammon G. An international, randomized, double-blind, Phase 3 study of the specific active immunotherapy agent, onamelatucel-L (CanvaxinTM), compared with placebo as a post-surgical adjuvant in AJCC stage IV melanoma. Ann. Surg. Oncol. 13(Suppl. 2), 5 (2006).
    • (2006) Ann. Surg. Oncol , vol.13 , Issue.SUPPL. 2 , pp. 5
    • Morton, D.L.1    Thompson, J.F.2    Kashani-Sabet, M.3    Kelley, M.4    Gammon, G.5
  • 46
    • 0037089672 scopus 로고    scopus 로고
    • Sosman JA, Unger JM, Liu PY et al. Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: impact of HLA class I antigen expression on outcome. J. Clin. Oncol. 20(8), 2067-2075 (2002). • First article demonstrating the clinical relevance of HLA expression in terms of adjuvant therapy of melanoma with a vaccine.
    • Sosman JA, Unger JM, Liu PY et al. Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: impact of HLA class I antigen expression on outcome. J. Clin. Oncol. 20(8), 2067-2075 (2002). • First article demonstrating the clinical relevance of HLA expression in terms of adjuvant therapy of melanoma with a vaccine.
  • 47
    • 34249941065 scopus 로고    scopus 로고
    • Randomized trial of an allogeneic melanoma lysate vaccine with low-dose interferon α-2b compared with high-dose interferon α-2b for resected stage III cutaneous melanoma
    • Mitchell MS, Abrams J, Thompson JA et al. Randomized trial of an allogeneic melanoma lysate vaccine with low-dose interferon α-2b compared with high-dose interferon α-2b for resected stage III cutaneous melanoma. J. Clin. Oncol. 25(15), 2078-2085 (2007).
    • (2007) J. Clin. Oncol , vol.25 , Issue.15 , pp. 2078-2085
    • Mitchell, M.S.1    Abrams, J.2    Thompson, J.A.3
  • 48
    • 0027788002 scopus 로고
    • Pooled analysis of the efficacy of bacille Calmette-Guerin (BCG) immunotherapy in malignant melanoma
    • Tan JK, Ho VC. Pooled analysis of the efficacy of bacille Calmette-Guerin (BCG) immunotherapy in malignant melanoma. J. Dermatol. Surg. Oncol. 19(11), 985-990 (1993).
    • (1993) J. Dermatol. Surg. Oncol , vol.19 , Issue.11 , pp. 985-990
    • Tan, J.K.1    Ho, V.C.2
  • 49
    • 1842582038 scopus 로고    scopus 로고
    • Agarwala SS, Neuberg D, Park Y, Kirkwood JM. Mature results of a Phase III randomized trial of bacillus Calmette-Guerin (BCG) versus observation and BCG plus dacarbazine versus BCG in the adjuvant therapy of American Joint Committee on cancer stage I-III melanoma (E1673): a trial of the Eastern oncology group. Cancer 100(8), 1692-1698 (2004). • Mature results of a large, randomized cooperative group trial of bacillus Calmette- Guérin definitely indicating the lack of benefit of this form of nonspecific immunotherapy in stage I-III melanoma.
    • Agarwala SS, Neuberg D, Park Y, Kirkwood JM. Mature results of a Phase III randomized trial of bacillus Calmette-Guerin (BCG) versus observation and BCG plus dacarbazine versus BCG in the adjuvant therapy of American Joint Committee on cancer stage I-III melanoma (E1673): a trial of the Eastern oncology group. Cancer 100(8), 1692-1698 (2004). • Mature results of a large, randomized cooperative group trial of bacillus Calmette- Guérin definitely indicating the lack of benefit of this form of nonspecific immunotherapy in stage I-III melanoma.
  • 50
    • 35948972459 scopus 로고    scopus 로고
    • Slingluff CL Jr, Petroni GR, Chianese-Bullock KA et al. Immunologic and clinical outcomes of a randomized Phase II trial of two multipeptide vaccines for melanoma in the adjuvant setting. Clin. Cancer Res. 13(21), 6386-6395 (2007). • Study that showed the importance and potential of multiepitope peptide vaccines. This concept is the current focus of a large cooperative group trial.
    • Slingluff CL Jr, Petroni GR, Chianese-Bullock KA et al. Immunologic and clinical outcomes of a randomized Phase II trial of two multipeptide vaccines for melanoma in the adjuvant setting. Clin. Cancer Res. 13(21), 6386-6395 (2007). • Study that showed the importance and potential of multiepitope peptide vaccines. This concept is the current focus of a large cooperative group trial.
  • 51
    • 0031890206 scopus 로고    scopus 로고
    • Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
    • Rosenberg SA, Yang JC, Schwartzentruber DJ et al. Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma. Nat. Med. 4(3), 321-327 (1998).
    • (1998) Nat. Med , vol.4 , Issue.3 , pp. 321-327
    • Rosenberg, S.A.1    Yang, J.C.2    Schwartzentruber, D.J.3
  • 52
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: Moving beyond current vaccines
    • Rosenberg SA, Yang JC, Restifo NP. Cancer immunotherapy: moving beyond current vaccines. Nat. Med. 10(9), 909-915 (2004).
    • (2004) Nat. Med , vol.10 , Issue.9 , pp. 909-915
    • Rosenberg, S.A.1    Yang, J.C.2    Restifo, N.P.3
  • 53
    • 33645325115 scopus 로고    scopus 로고
    • Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DCs) in first-line treatment of patients with metastatic melanoma: A randomized Phase III trial of the DC study group of the DeCOG
    • First well-conducted, randomized trial comparing the standard chemotherapy for stage IV melanoma with vaccine therapy, •
    • Schadendorf D, Ugurel S, Schuler-Thurner B et al. Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DCs) in first-line treatment of patients with metastatic melanoma: a randomized Phase III trial of the DC study group of the DeCOG. Ann. Oncol. 17(4), 563-570 (2006). • First well-conducted, randomized trial comparing the standard chemotherapy for stage IV melanoma with vaccine therapy.
    • (2006) Ann. Oncol , vol.17 , Issue.4 , pp. 563-570
    • Schadendorf, D.1    Ugurel, S.2    Schuler-Thurner, B.3
  • 54
    • 28844471692 scopus 로고    scopus 로고
    • Tumoral and immunologic response after vaccination of melanoma patients with an ALVAC virus encoding MAGE antigens recognized by T cells
    • van Baren N, Bonnet MC, Dreno B et al. Tumoral and immunologic response after vaccination of melanoma patients with an ALVAC virus encoding MAGE antigens recognized by T cells. J. Clin. Oncol. 23(35), 9008-9021 (2005).
    • (2005) J. Clin. Oncol , vol.23 , Issue.35 , pp. 9008-9021
    • van Baren, N.1    Bonnet, M.C.2    Dreno, B.3
  • 55
    • 45549103395 scopus 로고    scopus 로고
    • Functions of anti-MAGE T-cells induced in melanoma patients under different vaccination modalities
    • Connerotte T, Van Pel A, Godelaine D et al. Functions of anti-MAGE T-cells induced in melanoma patients under different vaccination modalities. Cancer Res. 68(10), 3931-3940 (2008).
    • (2008) Cancer Res , vol.68 , Issue.10 , pp. 3931-3940
    • Connerotte, T.1    Van Pel, A.2    Godelaine, D.3
  • 56
    • 0028205790 scopus 로고
    • Improved survival in stage III melanoma patients with GM2 antibodies: A randomized trial of adjuvant vaccination with GM2 ganglioside
    • First trial to stimulate major interest in the GMK vaccine that led to two large, randomized studies with this agent in the adjuvant therapy of melanoma, •
    • Livingston PO, Wong GY, Adluri S et al. Improved survival in stage III melanoma patients with GM2 antibodies: a randomized trial of adjuvant vaccination with GM2 ganglioside. J. Clin. Oncol. 12(5), 1036-1044 (1994). • First trial to stimulate major interest in the GMK vaccine that led to two large, randomized studies with this agent in the adjuvant therapy of melanoma.
    • (1994) J. Clin. Oncol , vol.12 , Issue.5 , pp. 1036-1044
    • Livingston, P.O.1    Wong, G.Y.2    Adluri, S.3
  • 57
    • 33847640493 scopus 로고    scopus 로고
    • Immunosenescence: Emerging challenges for an ageing population
    • Aw D, Silva AB, Palmer DB. Immunosenescence: emerging challenges for an ageing population. Immunology 120(4), 435-446 (2007).
    • (2007) Immunology , vol.120 , Issue.4 , pp. 435-446
    • Aw, D.1    Silva, A.B.2    Palmer, D.B.3
  • 59
    • 0034201038 scopus 로고    scopus 로고
    • Cancer-induced defective cytotoxic T lymphocyte effector function: Another mechanism how antigenic tumors escape immune-mediated killing
    • Radoja S, Frey AB. Cancer-induced defective cytotoxic T lymphocyte effector function: another mechanism how antigenic tumors escape immune-mediated killing. Mol. Med. 6(6), 465-479 (2000).
    • (2000) Mol. Med , vol.6 , Issue.6 , pp. 465-479
    • Radoja, S.1    Frey, A.B.2
  • 60
    • 31344466956 scopus 로고    scopus 로고
    • Chronic inflammation, immunosuppression and cancer: New insights and outlook
    • Baniyash M. Chronic inflammation, immunosuppression and cancer: new insights and outlook. Semin. Cancer Biol. 16(1), 80-88 (2006).
    • (2006) Semin. Cancer Biol , vol.16 , Issue.1 , pp. 80-88
    • Baniyash, M.1
  • 61
    • 16844379997 scopus 로고    scopus 로고
    • Immunosuppressive networks in the tumour environment and their therapeutic relevance
    • Zou W. Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat. Rev. Cancer 5(4), 263-274 (2005).
    • (2005) Nat. Rev. Cancer , vol.5 , Issue.4 , pp. 263-274
    • Zou, W.1
  • 62
    • 0037013930 scopus 로고    scopus 로고
    • Mechanism of transforming growth factor β-induced inhibition of T helper type 1 differentiation
    • Gorelik L, Constant S, Flavell RA. Mechanism of transforming growth factor β-induced inhibition of T helper type 1 differentiation. J. Exp. Med. 195(11), 1499-1505 (2002).
    • (2002) J. Exp. Med , vol.195 , Issue.11 , pp. 1499-1505
    • Gorelik, L.1    Constant, S.2    Flavell, R.A.3
  • 63
    • 33646560950 scopus 로고    scopus 로고
    • Transforming growth factor-β induces development of the T(H)17 lineage
    • Mangan PR, Harrington LE, O'Quinn DB et al. Transforming growth factor-β induces development of the T(H)17 lineage. Nature 441(7090), 231-234 (2006).
    • (2006) Nature , vol.441 , Issue.7090 , pp. 231-234
    • Mangan, P.R.1    Harrington, L.E.2    O'Quinn, D.B.3
  • 65
    • 0031974687 scopus 로고    scopus 로고
    • IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages
    • Allavena P, Piemonti L, Longoni D et al. IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages. Eur. J. Immunol. 28(1), 359-369 (1998).
    • (1998) Eur. J. Immunol , vol.28 , Issue.1 , pp. 359-369
    • Allavena, P.1    Piemonti, L.2    Longoni, D.3
  • 66
    • 0025763807 scopus 로고
    • IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells
    • Fiorentino DF, Zlotnik A, Vieira P et al. IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. J. Immunol. 146(10), 3444-3451 (1991).
    • (1991) J. Immunol , vol.146 , Issue.10 , pp. 3444-3451
    • Fiorentino, D.F.1    Zlotnik, A.2    Vieira, P.3
  • 67
    • 0032400862 scopus 로고    scopus 로고
    • Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo
    • Gabrilovich D, Ishida T, Oyama T et al. Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo. Blood 92(11), 4150-4166 (1998).
    • (1998) Blood , vol.92 , Issue.11 , pp. 4150-4166
    • Gabrilovich, D.1    Ishida, T.2    Oyama, T.3
  • 68
    • 0031570886 scopus 로고    scopus 로고
    • + cells within human head and neck squamous cell carcinomas
    • + cells within human head and neck squamous cell carcinomas. J. Immunol. 159(2), 990-996 (1997).
    • (1997) J. Immunol , vol.159 , Issue.2 , pp. 990-996
    • Young, M.R.1    Wright, M.A.2    Pandit, R.3
  • 69
    • 0031835341 scopus 로고    scopus 로고
    • Immune response against human primary malignant melanoma: A distinct cytokine mRNA profile associated with spontaneous regression
    • Wagner SN, Schultewolter T, Wagner C et al. Immune response against human primary malignant melanoma: a distinct cytokine mRNA profile associated with spontaneous regression. Lab. Invest. 78(5), 541-550 (1998).
    • (1998) Lab. Invest , vol.78 , Issue.5 , pp. 541-550
    • Wagner, S.N.1    Schultewolter, T.2    Wagner, C.3
  • 72
    • 0141576738 scopus 로고    scopus 로고
    • Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma
    • Soiffer R, Hodi FS, Haluska F et al. Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma. J. Clin. Oncol. 21(17), 3343-3350 (2003).
    • (2003) J. Clin. Oncol , vol.21 , Issue.17 , pp. 3343-3350
    • Soiffer, R.1    Hodi, F.S.2    Haluska, F.3
  • 73
    • 0037108861 scopus 로고    scopus 로고
    • Hersey P, Coates AS, McCarthy WH et al. Adjuvant immunotherapy of patients with high-risk melanoma using vaccinia viral lysates of melanoma: results of a randomized trial. J. Clin. Oncol. 20(20), 4181-4190 (2002). • Large, randomized trial of adjuvant immunotherapy with a unique vaccine in resected melanoma.
    • Hersey P, Coates AS, McCarthy WH et al. Adjuvant immunotherapy of patients with high-risk melanoma using vaccinia viral lysates of melanoma: results of a randomized trial. J. Clin. Oncol. 20(20), 4181-4190 (2002). • Large, randomized trial of adjuvant immunotherapy with a unique vaccine in resected melanoma.
  • 74
    • 0037089687 scopus 로고    scopus 로고
    • Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: Overall results of a randomized trial of the Southwest Oncology Group
    • Sondak VK, Liu PY, Tuthill RJ et al. Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: overall results of a randomized trial of the Southwest Oncology Group. J. Clin. Oncol. 20(8), 2058-2066 (2002).
    • (2002) J. Clin. Oncol , vol.20 , Issue.8 , pp. 2058-2066
    • Sondak, V.K.1    Liu, P.Y.2    Tuthill, R.J.3
  • 75
    • 0027248953 scopus 로고
    • Active specific immunotherapy of melanoma with allogeneic cell lysates. Rationale, results, and possible mechanisms of action
    • Mitchell MS, Harel W, Kan-Mitchell J et al. Active specific immunotherapy of melanoma with allogeneic cell lysates. Rationale, results, and possible mechanisms of action. Ann. NY Acad. Sci. 690, 153-166 (1993).
    • (1993) Ann. NY Acad. Sci , vol.690 , pp. 153-166
    • Mitchell, M.S.1    Harel, W.2    Kan-Mitchell, J.3
  • 76
    • 0642311904 scopus 로고    scopus 로고
    • Clinical and immunologic results of a randomized Phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells
    • Slingluff CL Jr, Petroni GR, Yamshchikov GV et al. Clinical and immunologic results of a randomized Phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells. J. Clin. Oncol. 21(21), 4016-4026 (2003).
    • (2003) J. Clin. Oncol , vol.21 , Issue.21 , pp. 4016-4026
    • Slingluff Jr, C.L.1    Petroni, G.R.2    Yamshchikov, G.V.3
  • 77
    • 14044259609 scopus 로고    scopus 로고
    • Immunologic and clinical outcomes of vaccination with a multiepitope melanoma peptide vaccine plus low-dose interleukin-2 administered either concurrently or on a delayed schedule
    • Slingluff CL Jr, Petroni GR, Yamshchikov GV et al. Immunologic and clinical outcomes of vaccination with a multiepitope melanoma peptide vaccine plus low-dose interleukin-2 administered either concurrently or on a delayed schedule. J. Clin. Oncol. 22(22), 4474-4485 (2004).
    • (2004) J. Clin. Oncol , vol.22 , Issue.22 , pp. 4474-4485
    • Slingluff Jr, C.L.1    Petroni, G.R.2    Yamshchikov, G.V.3
  • 78
    • 39749186213 scopus 로고    scopus 로고
    • Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: The C-100-21 study group
    • Testori A, Richards J, Whitman E et al. Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: the C-100-21 study group. J. Clin. Oncol. 26(6), 955-962 (2008).
    • (2008) J. Clin. Oncol , vol.26 , Issue.6 , pp. 955-962
    • Testori, A.1    Richards, J.2    Whitman, E.3
  • 79
    • 35548944929 scopus 로고    scopus 로고
    • Safety and immunogenicity of tyrosinase DNA vaccines in patients with melanoma
    • Wolchok JD, Yuan J, Houghton AN et al. Safety and immunogenicity of tyrosinase DNA vaccines in patients with melanoma. Mol. Ther. 15(11), 2044-2050 (2007).
    • (2007) Mol. Ther , vol.15 , Issue.11 , pp. 2044-2050
    • Wolchok, J.D.1    Yuan, J.2    Houghton, A.N.3
  • 80
    • 33846322927 scopus 로고    scopus 로고
    • Alum with interleukin-12 augments immunity to a melanoma peptide vaccine: Correlation with time to relapse in patients with resected high-risk disease
    • Hamid O, Solomon JC, Scotland R et al. Alum with interleukin-12 augments immunity to a melanoma peptide vaccine: correlation with time to relapse in patients with resected high-risk disease. Clin. Cancer Res. 13(1), 215-222 (2007).
    • (2007) Clin. Cancer Res , vol.13 , Issue.1 , pp. 215-222
    • Hamid, O.1    Solomon, J.C.2    Scotland, R.3
  • 81
    • 33646428631 scopus 로고    scopus 로고
    • Evaluation of prime/boost regimens using recombinant poxvirus/tyrosinase vaccines for the treatment of patients with metastatic melanoma
    • Lindsey KR, Gritz L, Sherry R et al. Evaluation of prime/boost regimens using recombinant poxvirus/tyrosinase vaccines for the treatment of patients with metastatic melanoma. Clin. Cancer Res. 12(8), 2526-2537 (2006).
    • (2006) Clin. Cancer Res , vol.12 , Issue.8 , pp. 2526-2537
    • Lindsey, K.R.1    Gritz, L.2    Sherry, R.3
  • 82
    • 29144432729 scopus 로고    scopus 로고
    • Immunodominance of poxviral-specific CTL in a human trial of recombinant-modified vaccinia Ankara
    • Smith CL, Mirza F, Pasquetto V et al. Immunodominance of poxviral-specific CTL in a human trial of recombinant-modified vaccinia Ankara. J. Immunol. 175(12), 8431-8437 (2005).
    • (2005) J. Immunol , vol.175 , Issue.12 , pp. 8431-8437
    • Smith, C.L.1    Mirza, F.2    Pasquetto, V.3
  • 83
    • 7444253937 scopus 로고    scopus 로고
    • Immunization of HLA-A*0201 and/or HLA-DPβ1*04 patients with metastatic melanoma using epitopes from the NY-ESO-1 antigen
    • Khong HT, Yang JC, Topalian SL et al. Immunization of HLA-A*0201 and/or HLA-DPβ1*04 patients with metastatic melanoma using epitopes from the NY-ESO-1 antigen. J. Immunother. 27(6), 472-477 (2004).
    • (2004) J. Immunother , vol.27 , Issue.6 , pp. 472-477
    • Khong, H.T.1    Yang, J.C.2    Topalian, S.L.3
  • 84
    • 3242695961 scopus 로고    scopus 로고
    • Sequential immunization of melanoma patients with GD3 ganglioside vaccine and anti-idiotypic monoclonal antibody that mimics GD3 ganglioside
    • Chapman PB, Wu D, Ragupathi G et al. Sequential immunization of melanoma patients with GD3 ganglioside vaccine and anti-idiotypic monoclonal antibody that mimics GD3 ganglioside. Clin. Cancer Res. 10(14), 4717-4723 (2004).
    • (2004) Clin. Cancer Res , vol.10 , Issue.14 , pp. 4717-4723
    • Chapman, P.B.1    Wu, D.2    Ragupathi, G.3
  • 85
    • 3142600876 scopus 로고    scopus 로고
    • A Phase II trial comparing five dose levels of BEC2 anti-idiotypic monoclonal antibody vaccine that mimics GD3 ganglioside
    • Chapman PB, Williams L, Salibi N, Hwu WJ, Krown SE, Livingston PO. A Phase II trial comparing five dose levels of BEC2 anti-idiotypic monoclonal antibody vaccine that mimics GD3 ganglioside. Vaccine 22(21-22), 2904-2909 (2004).
    • (2004) Vaccine , vol.22 , Issue.21-22 , pp. 2904-2909
    • Chapman, P.B.1    Williams, L.2    Salibi, N.3    Hwu, W.J.4    Krown, S.E.5    Livingston, P.O.6
  • 86
    • 1642576146 scopus 로고    scopus 로고
    • Phase I trial of large multivalent immunogen derived from melanoma lysates in patients with disseminated melanoma
    • Mitchell MS, Kan-Mitchell J, Morrow PR, Darrah D, Jones VE, Mescher MF. Phase I trial of large multivalent immunogen derived from melanoma lysates in patients with disseminated melanoma. Clin. Cancer Res. 10(1 Pt 1), 76-83 (2004).
    • (2004) Clin. Cancer Res , vol.10 , Issue.1 PART 1 , pp. 76-83
    • Mitchell, M.S.1    Kan-Mitchell, J.2    Morrow, P.R.3    Darrah, D.4    Jones, V.E.5    Mescher, M.F.6
  • 87
    • 0142055970 scopus 로고    scopus 로고
    • + T-cell function in melanoma patients
    • + T-cell function in melanoma patients. J. Clin. Oncol. 21(20), 3826-3835 (2003).
    • (2003) J. Clin. Oncol , vol.21 , Issue.20 , pp. 3826-3835
    • Bedrosian, I.1    Mick, R.2    Xu, S.3
  • 88
    • 0041365767 scopus 로고    scopus 로고
    • A randomized Phase II trial of SRL172 (Mycobacterium vaccae) ± low-dose interleukin-2 in the treatment of metastatic malignant melanoma
    • Nicholson S, Guile K, John J et al. A randomized Phase II trial of SRL172 (Mycobacterium vaccae) ± low-dose interleukin-2 in the treatment of metastatic malignant melanoma. Melanoma Res, 13(4), 389-393 (2003).
    • (2003) Melanoma Res , vol.13 , Issue.4 , pp. 389-393
    • Nicholson, S.1    Guile, K.2    John, J.3
  • 89
    • 0038167081 scopus 로고    scopus 로고
    • Interferon-γ or granulocyte-macrophage colony-stimulating factor administered as adjuvants with a vaccine of irradiated autologous tumor cells from short-term cell line cultures: A randomized Phase 2 trial of the cancer biotherapy research group
    • Dillman RO, Wiemann M, Nayak SK, DeLeon C, Hood K, DePriest C. Interferon-γ or granulocyte-macrophage colony-stimulating factor administered as adjuvants with a vaccine of irradiated autologous tumor cells from short-term cell line cultures: a randomized Phase 2 trial of the cancer biotherapy research group. J. Immunother. 26(4), 367-373 (2003).
    • (2003) J. Immunother , vol.26 , Issue.4 , pp. 367-373
    • Dillman, R.O.1    Wiemann, M.2    Nayak, S.K.3    DeLeon, C.4    Hood, K.5    DePriest, C.6
  • 90
    • 0038697491 scopus 로고    scopus 로고
    • Inability to immunize patients with metastatic melanoma using plasmid DNA encoding the gp100 melanoma-melanocyte antigen
    • Rosenberg SA, Yang JC, Sherry RM et al. Inability to immunize patients with metastatic melanoma using plasmid DNA encoding the gp100 melanoma-melanocyte antigen. Hum. Gene Ther. 14(8), 709-714 (2003).
    • (2003) Hum. Gene Ther , vol.14 , Issue.8 , pp. 709-714
    • Rosenberg, S.A.1    Yang, J.C.2    Sherry, R.M.3
  • 92
    • 0037431558 scopus 로고    scopus 로고
    • Clinical and immunological evaluation of patients with metastatic melanoma undergoing immunization with the HLA-Cw*0702-associated epitope MAGE-A
    • Bettinotti MP, Panelli MC, Ruppe E et al. Clinical and immunological evaluation of patients with metastatic melanoma undergoing immunization with the HLA-Cw*0702-associated epitope MAGE-A12:170-178. Int. J. Cancer 105(2), 210-216 (2003).
    • (2003) Int. J. Cancer , vol.105 , Issue.2 , pp. 210-216
    • Bettinotti, M.P.1    Panelli, M.C.2    Ruppe, E.3


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