Transgenic tomato expressing interleukin-12 has a therapeutic effect in a murine model of progressive pulmonary tuberculosis

Clinical and Experimental Immunology

Volumn 154, Issue 1, 2008, Pages 123-133

  Elias Lopez A L ^b   Marquina, B ^b   Gutierrez Ortega A ^c   Aguilar, D ^b   Gomez Lim, M ^c   Hernandez Pando R ^a,b  

^a INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

^b Instituto Nacional de Ciencias Médicas Y Nutrición 'Salvador Zubirán'

^c DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

IL 12; Multi drug resistant tuberculosis; Oral therapy; Pulmonary tuberculosis; Transgenic tomato

Indexed keywords

PLANT EXTRACT; RECOMBINANT INTERLEUKIN 12;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; BAGG ALBINO MOUSE; CELLULAR IMMUNITY; CONTROLLED STUDY; DRUG EFFICACY; EXPERIMENTAL MODEL; GENE EXPRESSION; INFECTION RESISTANCE; LUNG INJURY; LUNG TUBERCULOSIS; MALE; MOUSE; MULTIDRUG RESISTANCE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; TH1 CELL; TH2 CELL; TOMATO; TRANSGENIC PLANT; TREATMENT OUTCOME; WILD TYPE;

ANIMALS; HUMANS; IMMUNOTHERAPY; INTERLEUKIN-12; LUNG; LYCOPERSICON ESCULENTUM; MALE; MICE; MICE, INBRED BALB C; PLANT EXTRACTS; PLANTS, GENETICALLY MODIFIED; TH1 CELLS; TIME; TUBERCULOSIS, MULTIDRUG-RESISTANT; TUBERCULOSIS, PULMONARY;

EID: 51349114738     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2008.03723.x     Document Type: Article

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