Correlation between the kinetics of Th1/Th2 cells and pathology in a murine model of experimental pulmonary tuberculosis

Immunology

Volumn 89, Issue 1, 1996, Pages 26-33

  Hernandez Pando R ^a   Orozcoe, H ^a   Sampieri, A ^b   Pavon L ^a   Velasquillo, C ^a   Larriva Sahd, J ^a,c   Alcocer, J M ^b   Madrid, M V ^b  

^a INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

^b Ctro Invest Sobre Enferm I   (Mexico)

^c UNIVERSIDAD LA SALLE   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; GRANULOMA; HELPER CELL; IMMUNOHISTOCHEMISTRY; KINETICS; LUNG TUBERCULOSIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; BLOTTING, SOUTHERN; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; INTERFERON TYPE II; INTERLEUKIN-2; INTERLEUKIN-4; LUNG; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; POLYMERASE CHAIN REACTION; TH1 CELLS; TH2 CELLS; TIME FACTORS; TUBERCULOSIS, PULMONARY;

EID: 0029791631     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. ROOK G.A.W., ONYEBUJOH P. & STANFORD J. (1993) Th-1 - Th-2 switch and loss of CD-4 cells in chronic infections: an immunoendocrinological hypothesis not exclusive to HIV. Immunol Today 14, 568.
2. SHER A., GAZZINETTI R.T., OSWALD I.P. et al. (1992) Role of T-cell derived cytokines in the down-regulation of immune responses in parasitic and retroviral infection. Immunol Rev 127, 183.
3. MOSSMANN T.R., CHERWINSKI H., BOND M.W., GIDLIN M.A. & COFFMAN R.L. (1986) Two types of murine helper T cell clones I. Definition according to profiles of lymphokines activities and secreted proteins. J Immunol 136, 2348.
4. SURCEI H.M., TRYE-BLOMBERG M., PAULIE S. et al. (1994) Th1/Th2 profiles in tuberculosis, based on the proliferation and cytokine response of blood lymphocytes to mycobacterial antigens. Immunology 81, 171.
5. ORME I.M., ROBERTS A.D., GRIFFIN J.P. & ABRAMS J.S. (1993) Cytokine secretion by CD4 T lymphocytes acquired in response to Mycobacterium tuberculosis infection. J Immunol 151, 518.
6. HERNÁNDEZ-PANDO R., OROZCO H., HONOUR J., SILVA P., LEYVA R. & ROOK G.A.W. (1995) Adrenal changes in murine pulmonary tuberculosis; a clue to pathogenesis? FEMS Immunol Med Microbiol 12, 63.
7. JARNAGIN J.L. & LUCHSINGER D.W. (1980) The use of fluorescein diacetate and ethidium bromide as stain for evaluating viability of mycobacteria. Stain Technol 55, 253.
8. CHOMCZYNSKI P.A. (1993) Reagent for the single step simultaneous isolation of RNA, DNA and proteins from cells and tissue samples. Biotechniques 15, 532.
9. PIETSCH K., EHLERS S. & JACOBS E. (1994) Cytokine gene expression in the lung of BALB-c mice during primary and secondary intranasal infection with Mycoplasma pneumoniae. Microbiology 14, 2043.
10. HOLT P.G. (1986) Down-regulation of immune responses in the lower respiratory tract the role of alveolar macrophages. Clin Exp Immunol 63, 261.
11. BETZ M. & FOX B.S. (1991) Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines. J Immunol 146, 108.
12. AINSLIE G.M., BATEMAN E.D. & SOLOMON J.A. (1986) Variation of T lymphocytes numbers and subsets in different forms and stages of pulmonary tuberculosis. Am Rev Respir Dis 133, A39.
13. FERNANDEZ BOTRAN R., SANDERS V.M., MOSSMAN R.T. & VIETTA E.S. (1988) Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells. J Exp Med 168, 543.
14. TRINCHIERI G. (1993) Interleukin 12 and its role in the generation of Th 1 cells. Immunol Today 14, 335.
15. HEINZEI F.P., SANDICK M.D., MUHA S. & LOCKSLEY R.M. (1991) Production of interferon gamma, interleukin 2, interleukin 4 and interleukin 10 by CD4+ lymphocytes in vivo during healing and progressive murine leshmaniasis. Proc Natl Acad Sci USA 88, 7011.
16. SHER A., FIORENTINO D.F., CASPAR P., PEARSE E. & MOSSMAN T. (1991) Production of IL-10 by CD4+ T lymphocytes correlates with down regulation of TH-1 cytokine synthesis in helminth infection. J Immunol 147, 2713.
17. ORME I.M., MILLER E.S., ROBERTS A.D., BURNEY S.K., GRIFFIN J.P. & DOBOS K.M. (1992) T lymphocytes mediated protection and cellular cytolysis during the course of micobacterial infection. J Immunol 148, 189.
18. MÜLLER I., COBBOLD S.P., WALDMANN H. & KAUFFMAN S.H. (1987) Impaired resistance against Mycobacterium tuberculosis infection after selective in vivo depletion of L3T4+ and LyT2+ T cells. Infect Immun 55, 3037.
19. KIMENY M.D., NOBLE A., HOLMES B.J. & DIAZ-SANCHEZ D. (1994) Immune regulation: a new role for the CD8+ T cell. Immunol Today 15, 107.
20. YAMAMURA M., UYEMURA K., DEANS R.J. et al. (1991) Defining protecting responses to pathogens: cytokine profiles in leprosy lesions. Science 254, 277.
21. SALGAME P.R., ABRAMS J.S., CLAYBERGER C. et al. (1991) Differing lymphokine profiles of functional subsets of human CD-4 and CD-8 T cell clones. Science 254, 279.
22. SUSSMAN G. & WADEE A.A. (1991) Production of a suppressor factor by CD-8+ lymphocytes activated by mycobacterial components. J Immunol 59, 2828.
23. GRZYCH J.M., PEARSE E., CHEEVER A. et al. (1991) Egg deposition is the stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni. J Immunol 146, 1322.
24. ALWAN W.H., KOZLOWKA W.J. & OPENSHAW P.J.M. (1994) Distinct type of lung disease caused by functional subsets of antiviral T cell. J. Exp Med 179, 81.
25. HERNANDEZ-PANDO R. & ROOK G.A.W. (1994) The role of TNF alpha in T cells mediated inflammation depends on the Th1/Th2 cytokine balance. Immunology 82, 591.
26. ROOK G.A.W. & HERNANDEZ-PANDO R. (1994) T cell helper types and endocrines in the regulation of tissue damaging mechanisms in tuberculosis. Immunobiol 191, 478.
27. PEREIRA P. & TONEGAWA S. (1993) Gamma Delta cells. Annu Rev Immunol 11, 637.
28. BARNES P.F., GRISSO C.L., ABRAMS J.S., BAND H., REA T.H. & MODLIN R.L. (1992) Gamma delta T lymphocytes in human tuberculosis. J Infect Dis 165, 506.
29. INOUE T., YOSHIKAI Y., MATSUZAKI G. & NOMOTO K. (1991) Early appearing gamma delta bearing T cells during infection with Calmette Guerin Bacillus. J Immunol 146, 2754.
30. KAUFMANN S.H.E. & LADEL C. (1994) Application of knockout mice to the experimental analysis of infections with bacteria and protozoa. Trends Microbiol 2, 235.
31. FOLLOWS G.A., MUNK M.E., GATRILL J., CONRADT P. & KAUFMANN S.H. (1991) Gamma interferon and interleukin 2, but not interleukin 4, are detectable in gamma-delta T cell culture after activation with bacteria. Infect Immun 60, 1229.