N-acetylcysteine-mediated antioxidation prevents hyperglycemia-induced apoptosis and collagen synthesis in rat mesangial cells

American Journal of Nephrology

Volumn 29, Issue 3, 2009, Pages 192-202

  Hung, Kuan Yu ^a   Liu, Shin Yun ^a,b   Kao, Shu Huei ^b   Huang, Jenq Wen ^a   Chiang, Chih Kang ^a   Tsai, Tun Jun ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Fibrosis; Hyperglycemia; Mesangial cells; Mitochondria; N Acetylcysteine; Reactive oxygen species; TGF 1

Indexed keywords

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; COLLAGEN; CYTOCHROME C; LUCIFERASE; LUCIFERIN; MALONALDEHYDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL ASSAY; CELL CULTURE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RELEASE; FIBROGENESIS; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; MESANGIUM CELL; MITOCHONDRIAL MEMBRANE; NICK END LABELING; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; RENAL PROTECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CASPASES; CELLS, CULTURED; COLLAGEN; CYTOCHROMES C; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; FREE RADICAL SCAVENGERS; GENE EXPRESSION; HYPERGLYCEMIA; MALONDIALDEHYDE; MESANGIAL CELLS; POLY(ADP-RIBOSE) POLYMERASES; RATS; REACTIVE OXYGEN SPECIES; TRANSFORMING GROWTH FACTOR BETA1;

EID: 51349096398     PISSN: 02508095     EISSN: None     Source Type: Journal    
DOI: 10.1159/000155657     Document Type: Article

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