Depletion of intracellular zinc increases expression of tumorigenic cytokines VEGF, IL-6 and IL-8 in prostate cancer cells via NF-κB-dependent pathway

Prostate

Volumn 68, Issue 13, 2008, Pages 1443-1449

  Golovine, Konstantin ^a   Uzzo, Robert G ^a   Makhov, Peter ^a   Crispen, Paul L ^a   Kunkle, David ^a   Kolenko, Vladimir M ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

Cancer; Cytokines; NF B; Prostate; Zinc

Indexed keywords

GELATINASE B; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; PROTEIN P50; VASCULOTROPIN; ZINC; CATION TRANSPORT PROTEIN; CHELATING AGENT; ETHYLENEDIAMINE DERIVATIVE; N,N,N',N' TETRAKIS(2 PYRIDYLMETHYL)ETHYLENEDIAMINE; N,N,N',N'-TETRAKIS(2-PYRIDYLMETHYL)ETHYLENEDIAMINE; SLC39A1 PROTEIN, HUMAN; VASCULOTROPIN A;

ADENOVIRUS; ANGIOGENESIS; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; CANCER CELL; CARCINOGENICITY; CLINICAL FEATURE; CYTOKINE PRODUCTION; DEPLETION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; INCUBATION TIME; MEMBRANE PERMEABILITY; METASTASIS; PRIORITY JOURNAL; PROGNOSIS; PROSTATE CANCER; PROTEIN EXPRESSION; WESTERN BLOTTING; ZINC DEFICIENCY; ADENOCARCINOMA; GENETIC TRANSFECTION; GENETICS; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROSTATE TUMOR; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ADENOCARCINOMA; CATION TRANSPORT PROTEINS; CELL LINE, TUMOR; CHELATING AGENTS; ETHYLENEDIAMINES; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; MALE; MATRIX METALLOPROTEINASE 9; NF-KAPPA B; PROSTATIC NEOPLASMS; SIGNAL TRANSDUCTION; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; ZINC;

EID: 50949092384     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.20810     Document Type: Article

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