메뉴 건너뛰기




Volumn 13, Issue 3, 2008, Pages 279-288

The relevance of mouse models to understanding the development and progression of human breast cancer

Author keywords

Breast cancer; Mouse model

Indexed keywords

CELECOXIB; ESTROGEN RECEPTOR ALPHA; MEDROXYPROGESTERONE ACETATE; PROTEIN TYROSINE KINASE INHIBITOR; RETINOID DERIVATIVE; TAMOXIFEN;

EID: 50849102685     PISSN: 10833021     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10911-008-9093-5     Document Type: Review
Times cited : (36)

References (91)
  • 1
    • 38949105905 scopus 로고    scopus 로고
    • Ductal carcinoma in situ and the emergence of diversity during breast cancer evolution
    • doi: 10.1158/1078-0432.CCR-07-1127
    • Allred DC, Wu Y, Mao S, Nagtegaal ID, Lee S, Perou CM, et al. Ductal carcinoma in situ and the emergence of diversity during breast cancer evolution. Clin Cancer Res. 2008;14(2):370-8. doi: 10.1158/ 1078-0432.CCR-07-1127.
    • (2008) Clin Cancer Res , vol.14 , Issue.2 , pp. 370-378
    • Allred, D.C.1    Wu, Y.2    Mao, S.3    Nagtegaal, I.D.4    Lee, S.5    Perou, C.M.6
  • 2
    • 0015873713 scopus 로고
    • On the origin and progression of ductal carcinoma in the human breast
    • Wellings RR, Jensen HM. On the origin and progression of ductal carcinoma in the human breast. J Natl Cancer Inst. 1973;50:1111-8.
    • (1973) J Natl Cancer Inst , vol.50 , pp. 1111-1118
    • Wellings, R.R.1    Jensen, H.M.2
  • 3
    • 0016708393 scopus 로고
    • An atlas of subgross pathology of the human breast with special reference to possible precancerous lesions
    • Wellings SR, Jensen HM, Marcum RG. An atlas of subgross pathology of the human breast with special reference to possible precancerous lesions. J Natl Cancer Inst. 1975;55(2):231-73.
    • (1975) J Natl Cancer Inst , vol.55 , Issue.2 , pp. 231-273
    • Wellings, S.R.1    Jensen, H.M.2    Marcum, R.G.3
  • 4
    • 0032537990 scopus 로고    scopus 로고
    • Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 study
    • doi: 10.1093/jnci/90.18.1371
    • Fisher B, Costantino JP, Wickerham DL, Redmond CK, Kavanah M, Cronin WM, et al. Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 study. J Natl Cancer Inst. 1998;90(18):1371-88. doi: 10.1093/jnci/90.18.1371.
    • (1998) J Natl Cancer Inst , vol.90 , Issue.18 , pp. 1371-1388
    • Fisher, B.1    Costantino, J.P.2    Wickerham, D.L.3    Redmond, C.K.4    Kavanah, M.5    Cronin, W.M.6
  • 5
    • 33745249570 scopus 로고    scopus 로고
    • Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: The NSABP Study of Tamoxifen and Raloxifene STAR P-2 trial
    • doi: 10.1001/jama.295.23.joc60074
    • Vogel VG, Costantino JP, Wickerham DL, Cronin WM, Cecchini RS, Atkins JN, et al. Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: The NSABP Study of Tamoxifen and Raloxifene STAR P-2 trial. JAMA. 2006;295(23):2727-41. doi: 10.1001/jama.295.23.joc60074.
    • (2006) JAMA , vol.295 , Issue.23 , pp. 2727-2741
    • Vogel, V.G.1    Costantino, J.P.2    Wickerham, D.L.3    Cronin, W.M.4    Cecchini, R.S.5    Atkins, J.N.6
  • 6
    • 0002256421 scopus 로고    scopus 로고
    • Mouse models for mammary cancer
    • In: Asch BB, Ip MM, editors. New York: Kluwer Academic Press
    • Medina D. Mouse models for mammary cancer. In: Asch BB, Ip MM, editors. Methods in Mammary Gland Biology and Breast Cancer Research. New York: Kluwer Academic Press; 2000. p. 3-17.
    • (2000) Methods in Mammary Gland Biology and Breast Cancer Research , pp. 3-17
    • Medina, D.1
  • 7
    • 84965810273 scopus 로고
    • Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice
    • Deome KB, Faulkin LJ Jr, Bern HA, Blair PB. Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice. Cancer Res. 1959;19(5):515-20.
    • (1959) Cancer Res , vol.19 , Issue.5 , pp. 515-520
    • Deome, K.B.1    Faulkin Jr., L.J.2    Bern, H.A.3    Blair, P.B.4
  • 8
    • 50849088643 scopus 로고    scopus 로고
    • Premalignant and malignant mammary lesions induced by MMTV and chemical carcinogens
    • doi: 10.1007/s10911-008-9086-4
    • Medina D. Premalignant and malignant mammary lesions induced by MMTV and chemical carcinogens. J Mammary Gland Biol Neoplasia. 2008. doi: 10.1007/ s10911-008-9086-4.
    • (2008) J Mammary Gland Biol Neoplasia
    • Medina, D.1
  • 10
    • 36549043522 scopus 로고    scopus 로고
    • Special considerations in mouse models of breast cancer
    • Borowsky A. Special considerations in mouse models of breast cancer. Breast Dis. 2007;28:29-38.
    • (2007) Breast Dis , vol.28 , pp. 29-38
    • Borowsky, A.1
  • 11
    • 1642564339 scopus 로고    scopus 로고
    • Novel agents for the prevention of breast cancer: Targeting transcription factors and signal transduction pathways
    • doi: 10.1023/A:1025783221557
    • Shen Q, Brown PH. Novel agents for the prevention of breast cancer: targeting transcription factors and signal transduction pathways. J Mammary Gland Biol Neoplasia. 2003;8(1):45-73. doi: 10.1023/ A:1025783221557.
    • (2003) J Mammary Gland Biol Neoplasia , vol.8 , Issue.1 , pp. 45-73
    • Shen, Q.1    Brown, P.H.2
  • 12
    • 10944258521 scopus 로고    scopus 로고
    • Lack of sustained regression of c-MYC-induced mammary adenocarcinomas following brief or prolonged MYC inactivation
    • doi: 10.1016/j.ccr.2004.10.013
    • Boxer RB, Jang JW, Sintasath L, Chodosh LA. Lack of sustained regression of c-MYC-induced mammary adenocarcinomas following brief or prolonged MYC inactivation. Cancer Cell. 2004;6(6):577-86. doi: 10.1016/ j.ccr.2004.10.013.
    • (2004) Cancer Cell , vol.6 , Issue.6 , pp. 577-586
    • Boxer, R.B.1    Jang, J.W.2    Sintasath, L.3    Chodosh, L.A.4
  • 13
    • 36048959828 scopus 로고    scopus 로고
    • A role of estrogen/ERalpha signaling in BRCA1-associated tissue-specific tumor formation
    • doi: 10.1038/sj.onc.1210527
    • Li W, Xiao C, Vonderhaar BK, Deng CX. A role of estrogen/ERalpha signaling in BRCA1-associated tissue-specific tumor formation. Oncogene. 2007;26(51):7204-12. doi: 10.1038/sj.onc.1210527.
    • (2007) Oncogene , vol.26 , Issue.51 , pp. 7204-7212
    • Li, W.1    Xiao, C.2    Vonderhaar, B.K.3    Deng, C.X.4
  • 14
    • 2442701845 scopus 로고    scopus 로고
    • Somatic mutation of p53 leads to estrogen receptor alpha-positive and -negative mouse mammary tumors with high frequency of metastasis
    • doi: 10.1158/0008-5472.CAN-03-3524
    • Lin SC, Lee KF, Nikitin AY, Hilsenbeck SG, Cardiff RD, Li A, et al. Somatic mutation of p53 leads to estrogen receptor alpha-positive and -negative mouse mammary tumors with high frequency of metastasis. Cancer Res. 2004;64(10):3525-32. doi: 10.1158/0008-5472.CAN-03-3524.
    • (2004) Cancer Res , vol.64 , Issue.10 , pp. 3525-3532
    • Lin, S.C.1    Lee, K.F.2    Nikitin, A.Y.3    Hilsenbeck, S.G.4    Cardiff, R.D.5    Li, A.6
  • 15
    • 33750379861 scopus 로고    scopus 로고
    • Isoform-specific ras activation and oncogene dependence during MYC- and Wnt-induced mammary tumorigenesis
    • doi: 10.1128/MCB.00404-06
    • Jang JW, Boxer RB, Chodosh LA. Isoform-specific ras activation and oncogene dependence during MYC- and Wnt-induced mammary tumorigenesis. Mol Cell Biol. 2006;26(21):8109-21. doi: 10.1128/MCB.00404-06.
    • (2006) Mol Cell Biol , vol.26 , Issue.21 , pp. 8109-8121
    • Jang, J.W.1    Boxer, R.B.2    Chodosh, L.A.3
  • 16
    • 34147172890 scopus 로고    scopus 로고
    • RCAS-TVA in the mammary gland: An in vivo oncogene screen and a high fidelity model for breast transformation?
    • Du Z, Li Y. RCAS-TVA in the mammary gland: An in vivo oncogene screen and a high fidelity model for breast transformation? Cell Cycle. 2007;6(7):823-6.
    • (2007) Cell Cycle , vol.6 , Issue.7 , pp. 823-826
    • Du, Z.1    Li, Y.2
  • 17
    • 0034458540 scopus 로고    scopus 로고
    • Genetically engineered mouse models of mammary intraepithelial neoplasia
    • doi: 10.1023/A:1009534129331
    • Cardiff RD, Moghanaki D, Jensen RA. Genetically engineered mouse models of mammary intraepithelial neoplasia. J Mammary Gland Biol Neoplasia. 2000;5(4):421-37. doi: 10.1023/A:1009534129331.
    • (2000) J Mammary Gland Biol Neoplasia , vol.5 , Issue.4 , pp. 421-437
    • Cardiff, R.D.1    Moghanaki, D.2    Jensen, R.A.3
  • 18
    • 0016250571 scopus 로고
    • Hormone-dependent mammary tumors in strain GR-A mice. I. Alternation between ductal and tumorous phases of growth during serial transplantation
    • Aidells BD, Daniel CW. Hormone-dependent mammary tumors in strain GR-A mice. I. Alternation between ductal and tumorous phases of growth during serial transplantation. J Natl Cancer Inst. 1974;52(6):1855-63.
    • (1974) J Natl Cancer Inst , vol.52 , Issue.6 , pp. 1855-1863
    • Aidells, B.D.1    Daniel, C.W.2
  • 19
    • 0017806117 scopus 로고
    • Hormone-dependent mammary tumors in strain GR/A mice. IV. Origin and progression
    • Aidells BD, Daniel CW. Hormone-dependent mammary tumors in strain GR/A mice. IV. Origin and progression. J Natl Cancer Inst. 1978;60(6):1345-50.
    • (1978) J Natl Cancer Inst , vol.60 , Issue.6 , pp. 1345-1350
    • Aidells, B.D.1    Daniel, C.W.2
  • 20
    • 0027732897 scopus 로고
    • Progesterone induction of mammary carcinomas in BALB/c female mice. Correlation between progestin dependence and morphology
    • doi: 10.1007/BF00666353
    • Kordon EC, Molinolo AA, Pasqualini CD, Charreau EH, Pazos P, Dran G, et al. Progesterone induction of mammary carcinomas in BALB/c female mice. Correlation between progestin dependence and morphology. Breast Cancer Res Treat. 1993;28(1):29-39. doi: 10.1007/BF00666353.
    • (1993) Breast Cancer Res Treat , vol.28 , Issue.1 , pp. 29-39
    • Kordon, E.C.1    Molinolo, A.A.2    Pasqualini, C.D.3    Charreau, E.H.4    Pazos, P.5    Dran, G.6
  • 21
    • 0031878398 scopus 로고    scopus 로고
    • Promoter effect of medroxyprogesterone acetate (MPA) in N-methyl-N-nitrosourea (MNU) induced mammary tumors in BALB/c mice
    • doi: 10.1093/carcin/19.3.529
    • Pazos P, Lanari C, Elizalde P, Montecchia F, Charreau EH, Molinolo AA. Promoter effect of medroxyprogesterone acetate (MPA) in N-methyl-N-nitrosourea (MNU) induced mammary tumors in BALB/c mice. Carcinogenesis. 1998;19(3):529-31. doi: 10.1093/carcin/19.3.529.
    • (1998) Carcinogenesis , vol.19 , Issue.3 , pp. 529-531
    • Pazos, P.1    Lanari, C.2    Elizalde, P.3    Montecchia, F.4    Charreau, E.H.5    Molinolo, A.A.6
  • 22
    • 1242353199 scopus 로고    scopus 로고
    • Establishment of two hormone-responsive mouse mammary carcinoma cell lines derived from a metastatic mammary tumor
    • doi: 10.1023/B:BREA.0000014044.02728.ac
    • Efeyan A, Fabris V, Merani S, Lanari C, Molinolo AA. Establishment of two hormone-responsive mouse mammary carcinoma cell lines derived from a metastatic mammary tumor. Breast Cancer Res Treat. 2004;83(3):233-44. doi: 10.1023/B:BREA.0000014044.02728.ac.
    • (2004) Breast Cancer Res Treat , vol.83 , Issue.3 , pp. 233-244
    • Efeyan, A.1    Fabris, V.2    Merani, S.3    Lanari, C.4    Molinolo, A.A.5
  • 23
    • 0034696344 scopus 로고    scopus 로고
    • A mammary-specific model demonstrates the role of the p53 tumor suppressor gene in tumor development
    • doi: 10.1038/sj.onc.1203270
    • Jerry DJ, Kittrell FS, Kuperwasser C, Laucirica R, Dickinson ES, Bonilla PJ, et al. A mammary-specific model demonstrates the role of the p53 tumor suppressor gene in tumor development. Oncogene. 2000;19(8):1052-8. doi: 10.1038/sj.onc.1203270.
    • (2000) Oncogene , vol.19 , Issue.8 , pp. 1052-1058
    • Jerry, D.J.1    Kittrell, F.S.2    Kuperwasser, C.3    Laucirica, R.4    Dickinson, E.S.5    Bonilla, P.J.6
  • 24
    • 13644260907 scopus 로고    scopus 로고
    • Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome
    • doi: 10.1016/j.cell.2004.11.006
    • Lang GA, Iwakuma T, Suh YA, Liu G, Rao VA, Parant JM, et al. Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome. Cell. 2004;119(6):861-72. doi: 10.1016/j.cell.2004.11.006.
    • (2004) Cell , vol.119 , Issue.6 , pp. 861-872
    • Lang, G.A.1    Iwakuma, T.2    Suh, Y.A.3    Liu, G.4    Rao, V.A.5    Parant, J.M.6
  • 25
    • 17144405675 scopus 로고    scopus 로고
    • Tamoxifen inhibition of estrogen receptor-alpha-negative mouse mammary tumorigenesis
    • Medina D, Kittrell FS, Hill J, Shepard A, Thordarson G, Brown P. Tamoxifen inhibition of estrogen receptor-alpha-negative mouse mammary tumorigenesis. Cancer Res. 2005;65(8):3493-6.
    • (2005) Cancer Res , vol.65 , Issue.8 , pp. 3493-3496
    • Medina, D.1    Kittrell, F.S.2    Hill, J.3    Shepard, A.4    Thordarson, G.5    Brown, P.6
  • 26
    • 33845315093 scopus 로고    scopus 로고
    • Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist
    • doi: 10.1126/science.1130471
    • Poole AJ, Li Y, Kim Y, Lin SC, Lee WH, Lee EY. Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist. Science. 2006;314(5804):1467-70. doi: 10.1126/ science.1130471.
    • (2006) Science , vol.314 , Issue.5804 , pp. 1467-1470
    • Poole, A.J.1    Li, Y.2    Kim, Y.3    Lin, S.C.4    Lee, W.H.5    Lee, E.Y.6
  • 27
    • 7444223606 scopus 로고    scopus 로고
    • From mice to humans: Identification of commonly deregulated genes in mammary cancer via comparative SAGE studies
    • doi: 10.1158/0008-5472.CAN-04-1827
    • Hu Y, Sun H, Drake J, Kittrell F, Abba MC, Deng L, et al. From mice to humans: Identification of commonly deregulated genes in mammary cancer via comparative SAGE studies. Cancer Res. 2004;64(21):7748-55. doi: 10.1158/0008-5472.CAN-04-1827.
    • (2004) Cancer Res , vol.64 , Issue.21 , pp. 7748-7755
    • Hu, Y.1    Sun, H.2    Drake, J.3    Kittrell, F.4    Abba, M.C.5    Deng, L.6
  • 28
    • 13444272959 scopus 로고    scopus 로고
    • Deregulated estrogen receptor alpha expression in mammary epithelial cells of transgenic mice results in the development of ductal carcinoma in situ
    • Frech MS, Halama ED, Tilli MT, Singh B, Gunther EJ, Chodosh LA, et al. Deregulated estrogen receptor alpha expression in mammary epithelial cells of transgenic mice results in the development of ductal carcinoma in situ. Cancer Res. 2005;65(3):681-5.
    • (2005) Cancer Res , vol.65 , Issue.3 , pp. 681-685
    • Frech, M.S.1    Halama, E.D.2    Tilli, M.T.3    Singh, B.4    Gunther, E.J.5    Chodosh, L.A.6
  • 29
    • 38749087231 scopus 로고    scopus 로고
    • Activation of estrogen signaling pathways collaborates with loss of Brca1 to promote development of ERalpha-negative and ERalpha-positive mammary preneoplasia and cancer
    • doi: 10.1038/sj.onc.1210674
    • Jones LP, Tilli MT, Assefnia S, Torre K, Halama ED, Parrish A, et al. Activation of estrogen signaling pathways collaborates with loss of Brca1 to promote development of ERalpha-negative and ERalpha-positive mammary preneoplasia and cancer. Oncogene. 2008;27(6):794-802. doi: 10.1038/sj.onc.1210674.
    • (2008) Oncogene , vol.27 , Issue.6 , pp. 794-802
    • Jones, L.P.1    Tilli, M.T.2    Assefnia, S.3    Torre, K.4    Halama, E.D.5    Parrish, A.6
  • 30
    • 0142182119 scopus 로고    scopus 로고
    • Introduction of estrogen receptor-alpha into the tTA/TAg conditional mouse model precipitates the development of estrogen-responsive mammary adenocarcinoma
    • Tilli MT, Frech MS, Steed ME, Hruska KS, Johnson MD, Flaws JA, et al. Introduction of estrogen receptor-alpha into the tTA/TAg conditional mouse model precipitates the development of estrogen-responsive mammary adenocarcinoma. Am J Pathol. 2003;163(5):1713-9.
    • (2003) Am J Pathol , vol.163 , Issue.5 , pp. 1713-1719
    • Tilli, M.T.1    Frech, M.S.2    Steed, M.E.3    Hruska, K.S.4    Johnson, M.D.5    Flaws, J.A.6
  • 31
    • 33845191779 scopus 로고    scopus 로고
    • Genomic and transcriptional aberrations linked to breast cancer pathophysiologies
    • doi: 10.1016/j.ccr.2006.10.009
    • Chin K, DeVries S, Fridlyand J, Spellman PT, Roydasgupta R, Kuo WL, et al. Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell. 2006;10(6):529-41. doi: 10.1016/ j.ccr.2006.10.009.
    • (2006) Cancer Cell , vol.10 , Issue.6 , pp. 529-541
    • Chin, K.1    DeVries, S.2    Fridlyand, J.3    Spellman, P.T.4    Roydasgupta, R.5    Kuo, W.L.6
  • 32
    • 0034626769 scopus 로고    scopus 로고
    • The age of cancer
    • doi: 10.1038/35041694
    • DePinho RA. The age of cancer. Nature. 2000;408(6809):248-54. doi: 10.1038/35041694.
    • (2000) Nature , vol.408 , Issue.6809 , pp. 248-254
    • DePinho, R.A.1
  • 33
    • 33845209913 scopus 로고    scopus 로고
    • A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
    • doi: 10.1016/j.ccr.2006.10.008
    • Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T, et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell. 2006;10(6):515-27. doi: 10.1016/ j.ccr.2006.10.008.
    • (2006) Cancer Cell , vol.10 , Issue.6 , pp. 515-527
    • Neve, R.M.1    Chin, K.2    Fridlyand, J.3    Yeh, J.4    Baehner, F.L.5    Fevr, T.6
  • 34
    • 0033746030 scopus 로고    scopus 로고
    • Progesterone facilitates chromosome instability (aneuploidy) in p53 null normal mammary epithelial cells
    • doi: 10.1096/fj.00-0165com
    • Goepfert TM, McCarthy M, Kittrell FS, Stephens C, Ullrich RL, Brinkley BR, et al. Progesterone facilitates chromosome instability (aneuploidy) in p53 null normal mammary epithelial cells. FASEB J. 2000;14(14):2221-9. doi: 10.1096/fj.00-0165com.
    • (2000) FASEB J , vol.14 , Issue.14 , pp. 2221-2229
    • Goepfert, T.M.1    McCarthy, M.2    Kittrell, F.S.3    Stephens, C.4    Ullrich, R.L.5    Brinkley, B.R.6
  • 35
    • 4143100480 scopus 로고    scopus 로고
    • Hormone-induced chromosomal instability in p53-null mammary epithelium
    • doi: 10.1158/0008-5472.CAN-03-0629
    • Pati D, Haddad BR, Haegele A, Thompson H, Kittrell FS, Shepard A, et al. Hormone-induced chromosomal instability in p53-null mammary epithelium. Cancer Res. 2004;64(16):5608-16. doi: 10.1158/0008-5472.CAN-03-0629.
    • (2004) Cancer Res , vol.64 , Issue.16 , pp. 5608-5616
    • Pati, D.1    Haddad, B.R.2    Haegele, A.3    Thompson, H.4    Kittrell, F.S.5    Shepard, A.6
  • 36
    • 0036675318 scopus 로고    scopus 로고
    • Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer
    • doi: 10.1038/sj.onc.1205636
    • Weaver Z, Montagna C, Xu X, Howard T, Gadina M, Brodie SG, et al. Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer. Oncogene. 2002;21(33):5097-107. doi: 10.1038/sj.onc.1205636.
    • (2002) Oncogene , vol.21 , Issue.33 , pp. 5097-5107
    • Weaver, Z.1    Montagna, C.2    Xu, X.3    Howard, T.4    Gadina, M.5    Brodie, S.G.6
  • 37
    • 11144228109 scopus 로고    scopus 로고
    • Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI rats
    • doi: 10.1073/pnas.0408273101
    • Li JJ, Weroha SJ, Lingle WL, Papa D, Salisbury JL, Li SA. Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI rats. Proc Natl Acad Sci USA. 2004;101(52):18123-8. doi: 10.1073/pnas.0408273101.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.52 , pp. 18123-18128
    • Li, J.J.1    Weroha, S.J.2    Lingle, W.L.3    Papa, D.4    Salisbury, J.L.5    Li, S.A.6
  • 38
    • 33846626476 scopus 로고    scopus 로고
    • Heterogeneity of mammary lesions represent molecular differences
    • doi: 10.1186/1471-2407-6-275
    • Namba R, Maglione JE, Davis RR, Baron CA, Liu S, Carmack CE, et al. Heterogeneity of mammary lesions represent molecular differences. BMC Cancer. 2006;6:275. doi: 10.1186/1471-2407-6-275.
    • (2006) BMC Cancer , vol.6 , pp. 275
    • Namba, R.1    Maglione, J.E.2    Davis, R.R.3    Baron, C.A.4    Liu, S.5    Carmack, C.E.6
  • 39
    • 40749083242 scopus 로고    scopus 로고
    • Ovarian hyperstimulation induces centrosome amplification and aneuploid mammary tumors independently of alterations in p53 in a transgenic mouse model of breast cancer
    • doi: 10.1038/sj.onc.1210815
    • Milliken EL, Lozada KL, Johnson E, Landis MD, Seachrist DD, Whitten I, et al. Ovarian hyperstimulation induces centrosome amplification and aneuploid mammary tumors independently of alterations in p53 in a transgenic mouse model of breast cancer. Oncogene. 2008;27(12):1759-66. doi: 10.1038/sj.onc.1210815.
    • (2008) Oncogene , vol.27 , Issue.12 , pp. 1759-1766
    • Milliken, E.L.1    Lozada, K.L.2    Johnson, E.3    Landis, M.D.4    Seachrist, D.D.5    Whitten, I.6
  • 40
    • 32044460171 scopus 로고    scopus 로고
    • Pin1 regulates centrosome duplication, and its overexpression induces centrosome amplification, chromosome instability, and oncogenesis
    • doi: 10.1128/MCB.26.4.1463-1479.2006
    • Suizu F, Ryo A, Wulf G, Lim J, Lu KP. Pin1 regulates centrosome duplication, and its overexpression induces centrosome amplification, chromosome instability, and oncogenesis. Mol Cell Biol. 2006;26(4):1463-79. doi: 10.1128/MCB.26.4.1463-1479.2006.
    • (2006) Mol Cell Biol , vol.26 , Issue.4 , pp. 1463-1479
    • Suizu, F.1    Ryo, A.2    Wulf, G.3    Lim, J.4    Lu, K.P.5
  • 41
    • 33747751867 scopus 로고    scopus 로고
    • Mutation of the murine Bloom's syndrome gene produces global genome destabilization
    • doi: 10.1128/MCB.00296-06
    • Chester N, Babbe H, Pinkas J, Manning C, Leder P. Mutation of the murine Bloom's syndrome gene produces global genome destabilization. Mol Cell Biol. 2006;26(17):6713-26. doi: 10.1128/MCB.00296-06.
    • (2006) Mol Cell Biol , vol.26 , Issue.17 , pp. 6713-6726
    • Chester, N.1    Babbe, H.2    Pinkas, J.3    Manning, C.4    Leder, P.5
  • 42
    • 0036615473 scopus 로고    scopus 로고
    • Biological and genetic properties of the p53 null preneoplastic mammary epithelium
    • Medina D, Kittrell FS, Shepard A, Stephens LC, Jiang C, Lu J, et al. Biological and genetic properties of the p53 null preneoplastic mammary epithelium. FASEB J. 2002;16(8):881-3.
    • (2002) FASEB J , vol.16 , Issue.8 , pp. 881-883
    • Medina, D.1    Kittrell, F.S.2    Shepard, A.3    Stephens, L.C.4    Jiang, C.5    Lu, J.6
  • 43
    • 42149183454 scopus 로고    scopus 로고
    • The rexinoid, bexarotene, prevents the development of premalignant lesions in MMTV-erbB2 mice
    • doi: 10.1038/sj.bjc.6604320
    • Li Y, Zhang Y, Hill J, Kim HT, Shen Q, Bissonnette RP, et al. The rexinoid, bexarotene, prevents the development of premalignant lesions in MMTV-erbB2 mice. Br J Cancer. 2008;98(8):1380-8. doi: 10.1038/ sj.bjc.6604320.
    • (2008) Br J Cancer , vol.98 , Issue.8 , pp. 1380-1388
    • Li, Y.1    Zhang, Y.2    Hill, J.3    Kim, H.T.4    Shen, Q.5    Bissonnette, R.P.6
  • 45
    • 0034696284 scopus 로고    scopus 로고
    • A transgenic mouse model for the ductal carcinoma in situ (DCIS) of the mammary gland
    • doi: 10.1038/sj.onc.1203281
    • Schulze-Garg C, Lohler J, Gocht A, Deppert W. A transgenic mouse model for the ductal carcinoma in situ (DCIS) of the mammary gland. Oncogene. 2000;19(8):1028-37. doi: 10.1038/sj.onc.1203281.
    • (2000) Oncogene , vol.19 , Issue.8 , pp. 1028-1037
    • Schulze-Garg, C.1    Lohler, J.2    Gocht, A.3    Deppert, W.4
  • 46
    • 33947121226 scopus 로고    scopus 로고
    • Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation
    • doi: 10.1038/sj.onc.1209955
    • Jones RA, Campbell CI, Gunther EJ, Chodosh LA, Petrik JJ, Khokha R, et al. Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation. Oncogene. 2007;26(11):1636-44. doi: 10.1038/sj.onc.1209955.
    • (2007) Oncogene , vol.26 , Issue.11 , pp. 1636-1644
    • Jones, R.A.1    Campbell, C.I.2    Gunther, E.J.3    Chodosh, L.A.4    Petrik, J.J.5    Khokha, R.6
  • 47
    • 0035126052 scopus 로고    scopus 로고
    • c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations
    • doi: 10.1038/84691
    • D'Cruz CM, Gunther EJ, Boxer RB, Hartman JL, Sintasath L, Moody SE, et al. c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations. Nat Med. 2001;7(2):235-9. doi: 10.1038/84691.
    • (2001) Nat Med , vol.7 , Issue.2 , pp. 235-239
    • D'Cruz, C.M.1    Gunther, E.J.2    Boxer, R.B.3    Hartman, J.L.4    Sintasath, L.5    Moody, S.E.6
  • 48
    • 38349078213 scopus 로고    scopus 로고
    • Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by p19Arf/p53 pathway lesions but not p16 Ink4a loss
    • doi: 10.1172/JCI33320
    • Debies MT, Gestl SA, Mathers JL, Mikse OR, Leonard TL, Moody SE, et al. Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by p19Arf/p53 pathway lesions but not p16 Ink4a loss. J Clin Invest. 2008;118(1):51-63. doi: 10.1172/JCI33320.
    • (2008) J Clin Invest , vol.118 , Issue.1 , pp. 51-63
    • Debies, M.T.1    Gestl, S.A.2    Mathers, J.L.3    Mikse, O.R.4    Leonard, T.L.5    Moody, S.E.6
  • 49
    • 0037442760 scopus 로고    scopus 로고
    • Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis
    • doi: 10.1101/gad.1051603
    • Gunther EJ, Moody SE, Belka GK, Hahn KT, Innocent N, Dugan KD, et al. Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis. Genes Dev. 2003;17(4):488-501. doi: 10.1101/gad.1051603.
    • (2003) Genes Dev , vol.17 , Issue.4 , pp. 488-501
    • Gunther, E.J.1    Moody, S.E.2    Belka, G.K.3    Hahn, K.T.4    Innocent, N.5    Dugan, K.D.6
  • 50
    • 19044370434 scopus 로고    scopus 로고
    • Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis
    • doi: 10.1016/S1535-6108(02)00212-X
    • Moody SE, Sarkisian CJ, Hahn KT, Gunther EJ, Pickup S, Dugan KD, et al. Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis. Cancer Cell. 2002;2(6):451-61. doi: 10.1016/S1535-6108(02)00212-X.
    • (2002) Cancer Cell , vol.2 , Issue.6 , pp. 451-461
    • Moody, S.E.1    Sarkisian, C.J.2    Hahn, K.T.3    Gunther, E.J.4    Pickup, S.5    Dugan, K.D.6
  • 51
    • 36248932120 scopus 로고    scopus 로고
    • EMT tumorigenesis in the mouse mammary gland
    • doi: 10.1038/labinvest.3700683
    • Damonte P, Gregg JP, Borowsky AD, Keister BA, Cardiff RD. EMT tumorigenesis in the mouse mammary gland. Lab Invest. 2007;87(12):1218-26. doi: 10.1038/labinvest.3700683.
    • (2007) Lab Invest , vol.87 , Issue.12 , pp. 1218-1226
    • Damonte, P.1    Gregg, J.P.2    Borowsky, A.D.3    Keister, B.A.4    Cardiff, R.D.5
  • 52
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • doi: 10.1038/nrc822
    • Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer. 2002;2(6):442-54. doi: 10.1038/nrc822.
    • (2002) Nat Rev Cancer , vol.2 , Issue.6 , pp. 442-454
    • Thiery, J.P.1
  • 53
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • doi: 10.1038/nrm1835
    • Thiery JP, Sleeman JP. Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol. 2006;7(2):131-42. doi: 10.1038/nrm1835.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , Issue.2 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 54
    • 24944450362 scopus 로고    scopus 로고
    • The transcriptional repressor Snail promotes mammary tumor recurrence
    • doi: 10.1016/j.ccr.2005.07.009
    • Moody SE, Perez D, Pan TC, Sarkisian CJ, Portocarrero CP, Sterner CJ, et al. The transcriptional repressor Snail promotes mammary tumor recurrence. Cancer Cell. 2005;8(3):197-209. doi: 10.1016/ j.ccr.2005.07.009.
    • (2005) Cancer Cell , vol.8 , Issue.3 , pp. 197-209
    • Moody, S.E.1    Perez, D.2    Pan, T.C.3    Sarkisian, C.J.4    Portocarrero, C.P.5    Sterner, C.J.6
  • 55
    • 9244222742 scopus 로고    scopus 로고
    • Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors
    • doi: 10.1158/0008-5472.CAN-04-1136
    • Wang W, Goswami S, Lapidus K, Wells AL, Wyckoff JB, Sahai E, et al. Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors. Cancer Res. 2004;64(23):8585-94. doi: 10.1158/0008-5472.CAN-04-1136.
    • (2004) Cancer Res , vol.64 , Issue.23 , pp. 8585-8594
    • Wang, W.1    Goswami, S.2    Lapidus, K.3    Wells, A.L.4    Wyckoff, J.B.5    Sahai, E.6
  • 56
    • 0036828286 scopus 로고    scopus 로고
    • Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling
    • Wang W, Wyckoff JB, Frohlich VC, Oleynikov Y, Huttelmaier S, Zavadil J, et al. Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling. Cancer Res. 2002;62(21):6278-88.
    • (2002) Cancer Res , vol.62 , Issue.21 , pp. 6278-6288
    • Wang, W.1    Wyckoff, J.B.2    Frohlich, V.C.3    Oleynikov, Y.4    Huttelmaier, S.5    Zavadil, J.6
  • 57
    • 34248586312 scopus 로고    scopus 로고
    • Coordinated regulation of pathways for enhanced cell motility and chemotaxis is conserved in rat and mouse mammary tumors
    • doi: 10.1158/0008-5472.CAN-06-3714
    • Wang W, Wyckoff JB, Goswami S, Wang Y, Sidani M, Segall JE, et al. Coordinated regulation of pathways for enhanced cell motility and chemotaxis is conserved in rat and mouse mammary tumors. Cancer Res. 2007;67(8):3505-11. doi: 10.1158/0008-5472.CAN-06-3714.
    • (2007) Cancer Res , vol.67 , Issue.8 , pp. 3505-3511
    • Wang, W.1    Wyckoff, J.B.2    Goswami, S.3    Wang, Y.4    Sidani, M.5    Segall, J.E.6
  • 58
    • 0342545914 scopus 로고    scopus 로고
    • Tamoxifen chemoprevention of a hormone-independent tumor in the proto-neu transgenic mice model
    • Menard S, Aiello P, Tagliabue E, Rumio C, Lollini PL, Colnaghi MI, et al. Tamoxifen chemoprevention of a hormone-independent tumor in the proto-neu transgenic mice model. Cancer Res. 2000;60(2):273-5.
    • (2000) Cancer Res , vol.60 , Issue.2 , pp. 273-275
    • Menard, S.1    Aiello, P.2    Tagliabue, E.3    Rumio, C.4    Lollini, P.L.5    Colnaghi, M.I.6
  • 59
    • 34447637387 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators inhibit growth and progression of premalignant lesions in a mouse model of ductal carcinoma in situ
    • doi: 10.1186/bcr1317
    • Namba R, Young LJ, Maglione JE, McGoldrick ET, Liu S, Wurz GT, et al. Selective estrogen receptor modulators inhibit growth and progression of premalignant lesions in a mouse model of ductal carcinoma in situ. Breast Cancer Res. 2005;7(6):R881-889. doi: 10.1186/bcr1317.
    • (2005) Breast Cancer Res , vol.7 , Issue.6
    • Namba, R.1    Young, L.J.2    Maglione, J.E.3    McGoldrick, E.T.4    Liu, S.5    Wurz, G.T.6
  • 60
    • 0034671471 scopus 로고    scopus 로고
    • Estrogen promotes mammary tumor development in C3(1)/SV40 large T-antigen transgenic mice: Paradoxical loss of estrogen receptoralpha expression during tumor progression
    • Yoshidome K, Shibata MA, Couldrey C, Korach KS, Green JE. Estrogen promotes mammary tumor development in C3(1)/SV40 large T-antigen transgenic mice: Paradoxical loss of estrogen receptoralpha expression during tumor progression. Cancer Res. 2000;60(24):6901-10.
    • (2000) Cancer Res , vol.60 , Issue.24 , pp. 6901-6910
    • Yoshidome, K.1    Shibata, M.A.2    Couldrey, C.3    Korach, K.S.4    Green, J.E.5
  • 61
    • 35949000084 scopus 로고    scopus 로고
    • The Rexinoid LG100268 prevents the development of preinvasive and invasive estrogen receptor negative tumors in MMTV-erbB2 mice
    • doi: 10.1158/1078-0432.CCR-06-2681
    • Li Y, Zhang Y, Hill J, Shen Q, Kim HT, Xu X, et al. The Rexinoid LG100268 prevents the development of preinvasive and invasive estrogen receptor negative tumors in MMTV-erbB2 mice. Clin Cancer Res. 2007;13(20):6224-31. doi: 10.1158/1078-0432.CCR-06-2681.
    • (2007) Clin Cancer Res , vol.13 , Issue.20 , pp. 6224-6231
    • Li, Y.1    Zhang, Y.2    Hill, J.3    Shen, Q.4    Kim, H.T.5    Xu, X.6
  • 63
    • 9344255475 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitor induces apoptosis in breast cancer cells in an in vivo model of spontaneous metastatic breast cancer
    • Basu GD, Pathangey LB, Tinder TL, Lagioia M, Gendler SJ, Mukherjee P. Cyclooxygenase-2 inhibitor induces apoptosis in breast cancer cells in an in vivo model of spontaneous metastatic breast cancer. Mol Cancer Res. 2004;2(11):632-42.
    • (2004) Mol Cancer Res , vol.2 , Issue.11 , pp. 632-642
    • Basu, G.D.1    Pathangey, L.B.2    Tinder, T.L.3    Lagioia, M.4    Gendler, S.J.5    Mukherjee, P.6
  • 64
    • 33845927558 scopus 로고    scopus 로고
    • COX-2 inhibitor celecoxib suppresses tumor growth and lung metastasis of a murine mammary cancer
    • Yoshinaka R, Shibata MA, Morimoto J, Tanigawa N, Otsuki Y. COX-2 inhibitor celecoxib suppresses tumor growth and lung metastasis of a murine mammary cancer. Anticancer Res. 2006;26(6B):4245-54.
    • (2006) Anticancer Res , vol.26 , Issue.6 B , pp. 4245-4254
    • Yoshinaka, R.1    Shibata, M.A.2    Morimoto, J.3    Tanigawa, N.4    Otsuki, Y.5
  • 65
    • 0348230978 scopus 로고    scopus 로고
    • Effect of epidermal growth factor receptor inhibitor on development of estrogen receptor-negative mammary tumors
    • Lu C, Speers C, Zhang Y, Xu X, Hill J, Steinbis E, et al. Effect of epidermal growth factor receptor inhibitor on development of estrogen receptor-negative mammary tumors. J Natl Cancer Inst. 2003;95(24):1825-33.
    • (2003) J Natl Cancer Inst , vol.95 , Issue.24 , pp. 1825-1833
    • Lu, C.1    Speers, C.2    Zhang, Y.3    Xu, X.4    Hill, J.5    Steinbis, E.6
  • 66
    • 40349096373 scopus 로고    scopus 로고
    • Gefitinib prevents cancer progression in mice expressing the activated rat HER2/neu
    • doi: 10.1002/ijc.23231
    • Piechocki MP, Dibbley SK, Lonardo F, Yoo GH. Gefitinib prevents cancer progression in mice expressing the activated rat HER2/neu. Int J Cancer. 2008;122(8):1722-9. doi: 10.1002/ijc.23231.
    • (2008) Int J Cancer , vol.122 , Issue.8 , pp. 1722-1729
    • Piechocki, M.P.1    Dibbley, S.K.2    Lonardo, F.3    Yoo, G.H.4
  • 67
    • 0021019720 scopus 로고
    • Stage specificity of selenium-mediated inhibition of mouse mammary tumorigenesis
    • Medina D, Lane HW. Stage specificity of selenium-mediated inhibition of mouse mammary tumorigenesis. Biol Trace Elem Res. 1983;5:297-306.
    • (1983) Biol Trace Elem Res , vol.5 , pp. 297-306
    • Medina, D.1    Lane, H.W.2
  • 68
    • 34547691136 scopus 로고    scopus 로고
    • FOXA1 expression in breast cancer-correlation with luminal subtype A and survival
    • doi: 10.1158/1078-0432.CCR-07-0122
    • Badve S, Turbin D, Thorat MA, Morimiya A, Nielsen TO, Perou CM, et al. FOXA1 expression in breast cancer-correlation with luminal subtype A and survival. Clin Cancer Res. 2007;13(15 Pt 1):4415-21. doi: 10.1158/ 1078-0432.CCR-07-0122.
    • (2007) Clin Cancer Res , vol.13 , Issue.15 PART 1 , pp. 4415-4421
    • Badve, S.1    Turbin, D.2    Thorat, M.A.3    Morimiya, A.4    Nielsen, T.O.5    Perou, C.M.6
  • 69
    • 40949121882 scopus 로고    scopus 로고
    • Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype
    • doi: 10.1158/1078-0432.CCR-07-1658
    • Cheang MC, Voduc D, Bajdik C, Leung S, McKinney S, Chia SK, et al. Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype. Clin Cancer Res. 2008;14(5):1368-76. doi: 10.1158/1078-0432.CCR-07-1658.
    • (2008) Clin Cancer Res , vol.14 , Issue.5 , pp. 1368-1376
    • Cheang, M.C.1    Voduc, D.2    Bajdik, C.3    Leung, S.4    McKinney, S.5    Chia, S.K.6
  • 72
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • doi: 10.1073/pnas.191367098
    • Sorlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA. 2001;98(19):10869-74. doi: 10.1073/pnas.191367098.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.19 , pp. 10869-10874
    • Sorlie, T.1    Perou, C.M.2    Tibshirani, R.3    Aas, T.4    Geisler, S.5    Johnsen, H.6
  • 73
    • 0037478605 scopus 로고    scopus 로고
    • Repeated observation of breast tumor subtypes in independent gene expression data sets
    • doi: 10.1073/pnas.0932692100
    • Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci USA. 2003;100(14):8418-23. doi: 10.1073/pnas.0932692100.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.14 , pp. 8418-8423
    • Sorlie, T.1    Tibshirani, R.2    Parker, J.3    Hastie, T.4    Marron, J.S.5    Nobel, A.6
  • 74
    • 0037137519 scopus 로고    scopus 로고
    • A gene-expression signature as a predictor of survival in breast cancer
    • doi: 10.1056/NEJMoa021967
    • van de Vijver MJ, He YD, van't Veer LJ, Dai H, Hart AA, Voskuil DW, et al. A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med. 2002;347(25):1999-2009. doi: 10.1056/NEJMoa021967.
    • (2002) N Engl J Med , vol.347 , Issue.25 , pp. 1999-2009
    • van de Vijver, M.J.1    He, Y.D.2    van't Veer, L.J.3    Dai, H.4    Hart, A.A.5    Voskuil, D.W.6
  • 75
    • 34548863946 scopus 로고    scopus 로고
    • Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
    • doi: 10.1186/gb-2007-8-5-r76
    • Herschkowitz JI, Simin K, Weigman VJ, Mikaelian I, Usary J, Hu Z, et al. Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol. 2007;8(5):R76. doi: 10.1186/gb-2007-8-5-r76.
    • (2007) Genome Biol , vol.8 , Issue.5
    • Herschkowitz, J.I.1    Simin, K.2    Weigman, V.J.3    Mikaelian, I.4    Usary, J.5    Hu, Z.6
  • 76
    • 34548550432 scopus 로고    scopus 로고
    • Identification of an integrated SV40 T/t-antigen cancer signature in aggressive human breast, prostate, and lung carcinomas with poor prognosis
    • doi: 10.1158/0008-5472.CAN-07-1515
    • Deeb KK, Michalowska AM, Yoon CY, Krummey SM, Hoenerhoff MJ, Kavanaugh C, et al. Identification of an integrated SV40 T/t-antigen cancer signature in aggressive human breast, prostate, and lung carcinomas with poor prognosis. Cancer Res. 2007;67(17):8065-80. doi: 10.1158/ 0008-5472.CAN-07-1515.
    • (2007) Cancer Res , vol.67 , Issue.17 , pp. 8065-8080
    • Deeb, K.K.1    Michalowska, A.M.2    Yoon, C.Y.3    Krummey, S.M.4    Hoenerhoff, M.J.5    Kavanaugh, C.6
  • 77
    • 33750614651 scopus 로고    scopus 로고
    • Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis
    • doi: 10.1016/j.ccr.2006.09.013
    • Derksen PW, Liu X, Saridin F, van der Gulden H, Zevenhoven J, Evers B, et al. Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis. Cancer Cell. 2006;10(5):437-49. doi: 10.1016/j.ccr.2006.09.013.
    • (2006) Cancer Cell , vol.10 , Issue.5 , pp. 437-449
    • Derksen, P.W.1    Liu, X.2    Saridin, F.3    van der Gulden, H.4    Zevenhoven, J.5    Evers, B.6
  • 78
    • 34147193818 scopus 로고    scopus 로고
    • Constitutively active type I insulin-like growth factor receptor causes transformation and xenograft growth of immortalized mammary epithelial cells and is accompanied by an epithelial-to-mesenchymal transition mediated by NF-kappaB and snail
    • doi: 10.1128/MCB.01315-06
    • Kim HJ, Litzenburger BC, Cui X, Delgado DA, Grabiner BC, Lin X, et al. Constitutively active type I insulin-like growth factor receptor causes transformation and xenograft growth of immortalized mammary epithelial cells and is accompanied by an epithelial-to-mesenchymal transition mediated by NF-kappaB and snail. Mol Cell Biol. 2007;27(8):3165-75. doi: 10.1128/MCB.01315-06.
    • (2007) Mol Cell Biol , vol.27 , Issue.8 , pp. 3165-3175
    • Kim, H.J.1    Litzenburger, B.C.2    Cui, X.3    Delgado, D.A.4    Grabiner, B.C.5    Lin, X.6
  • 79
    • 33845383714 scopus 로고    scopus 로고
    • Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2
    • doi: 10.1128/MCB.00260-06
    • Dearth RK, Cui X, Kim HJ, Kuiatse I, Lawrence NA, Zhang X, et al. Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2. Mol Cell Biol. 2006;26(24):9302-14. doi: 10.1128/MCB.00260-06.
    • (2006) Mol Cell Biol , vol.26 , Issue.24 , pp. 9302-9314
    • Dearth, R.K.1    Cui, X.2    Kim, H.J.3    Kuiatse, I.4    Lawrence, N.A.5    Zhang, X.6
  • 80
    • 0028063478 scopus 로고
    • Mammary carcinoma cell lines of high and low metastatic potential differ not in extravasation but in subsequent migration and growth
    • doi: 10.1007/BF01755879
    • Morris VL, Koop S, MacDonald IC, Schmidt EE, Grattan M, Percy D, et al. Mammary carcinoma cell lines of high and low metastatic potential differ not in extravasation but in subsequent migration and growth. Clin Exp Metastasis. 1994;12(6):357-67. doi: 10.1007/BF01755879.
    • (1994) Clin Exp Metastasis , vol.12 , Issue.6 , pp. 357-367
    • Morris, V.L.1    Koop, S.2    MacDonald, I.C.3    Schmidt, E.E.4    Grattan, M.5    Percy, D.6
  • 81
    • 0032768313 scopus 로고    scopus 로고
    • A novel orthotopic model of breast cancer metastasis to bone
    • doi: 10.1023/A:1006689719505
    • Lelekakis M, Moseley JM, Martin TJ, Hards D, Williams E, Ho P, et al. A novel orthotopic model of breast cancer metastasis to bone. Clin Exp Metastasis. 1999;17(2):163-70. doi: 10.1023/A:1006689719505.
    • (1999) Clin Exp Metastasis , vol.17 , Issue.2 , pp. 163-170
    • Lelekakis, M.1    Moseley, J.M.2    Martin, T.J.3    Hards, D.4    Williams, E.5    Ho, P.6
  • 82
    • 0035884506 scopus 로고    scopus 로고
    • Blocking tumor growth, invasion, and metastasis by maspin in a syngeneic breast cancer model
    • Blocking tumor growth, invasion, and metastasis by maspin in a syngeneic breast cancer model. Cancer Res. 2001;61(18):6945-51.
    • (2001) Cancer Res , vol.61 , Issue.18 , pp. 6945-6951
  • 83
    • 44349152371 scopus 로고    scopus 로고
    • Increased COX2 expression enhances tumor-induced osteoclastic lesions in breast cancer bone metastasis
    • Li Z, Schem C, Shi YH, Medina D, Zhang M. Increased COX2 expression enhances tumor-induced osteoclastic lesions in breast cancer bone metastasis. Clin Exp Metastasis 2007;25(4):389-400.
    • (2007) Clin Exp Metastasis , vol.25 , Issue.4 , pp. 389-400
    • Li, Z.1    Schem, C.2    Shi, Y.H.3    Medina, D.4    Zhang, M.5
  • 84
    • 33746417036 scopus 로고    scopus 로고
    • Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: The role of extracellular matrix and its degrading enzymes
    • doi: 10.1101/sqb.2005.70.013
    • Bissell MJ, Kenny PA, Radisky DC. Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: The role of extracellular matrix and its degrading enzymes. Cold Spring Harb Symp Quant Biol. 2005;70:343-56. doi: 10.1101/ sqb.2005.70.013.
    • (2005) Cold Spring Harb Symp Quant Biol , vol.70 , pp. 343-356
    • Bissell, M.J.1    Kenny, P.A.2    Radisky, D.C.3
  • 85
    • 42049104333 scopus 로고    scopus 로고
    • Three-dimensional lithographically defined organotypic tissue arrays for quantitative analysis of morphogenesis and neoplastic progression
    • doi: 10.1038/nprot.2008.35
    • Nelson CM, Inman JL, Bissell MJ. Three-dimensional lithographically defined organotypic tissue arrays for quantitative analysis of morphogenesis and neoplastic progression. Nat Protocols. 2008;3(4):674-8. doi: 10.1038/nprot.2008.35.
    • (2008) Nat Protocols , vol.3 , Issue.4 , pp. 674-678
    • Nelson, C.M.1    Inman, J.L.2    Bissell, M.J.3
  • 86
    • 0034161922 scopus 로고    scopus 로고
    • Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells
    • Barcellos-Hoff MH, Ravani SA. Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells. Cancer Res. 2000;60(5):1254-60.
    • (2000) Cancer Res , vol.60 , Issue.5 , pp. 1254-1260
    • Barcellos-Hoff, M.H.1    Ravani, S.A.2
  • 87
    • 1842687362 scopus 로고    scopus 로고
    • Reconstruction of functionally normal and malignant human breast tissues in mice
    • doi: 10.1073/pnas.0401064101
    • Kuperwasser C, Chavarria T, Wu M, Magrane G, Gray JW, Carey L, et al. Reconstruction of functionally normal and malignant human breast tissues in mice. Proc Natl Acad Sci USA. 2004;101(14):4966-71. doi: 10.1073/ pnas.0401064101.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.14 , pp. 4966-4971
    • Kuperwasser, C.1    Chavarria, T.2    Wu, M.3    Magrane, G.4    Gray, J.W.5    Carey, L.6
  • 88
    • 3042749576 scopus 로고    scopus 로고
    • Role of infiltrated leucocytes in tumour growth and spread
    • doi: 10.1038/sj.bjc.6601705
    • Lin EY, Pollard JW. Role of infiltrated leucocytes in tumour growth and spread. Br J Cancer. 2004;90(11):2053-8. doi: 10.1038/sj.bjc.6601705.
    • (2004) Br J Cancer , vol.90 , Issue.11 , pp. 2053-2058
    • Lin, E.Y.1    Pollard, J.W.2
  • 89
    • 31044433663 scopus 로고    scopus 로고
    • Macrophages: Obligate partners for tumor cell migration, invasion, and metastasis
    • doi: 10.1016/j.cell.2006.01.007
    • Condeelis J, Pollard JW. Macrophages: Obligate partners for tumor cell migration, invasion, and metastasis. Cell. 2006;124(2):263-6. doi: 10.1016/j.cell.2006.01.007.
    • (2006) Cell , vol.124 , Issue.2 , pp. 263-266
    • Condeelis, J.1    Pollard, J.W.2
  • 90
    • 34347226359 scopus 로고    scopus 로고
    • Tumor-associated macrophages press the angiogenic switch in breast cancer
    • doi: 10.1158/0008-5472.CAN-07-0912
    • Lin EY, Pollard JW. Tumor-associated macrophages press the angiogenic switch in breast cancer. Cancer Res. 2007;67(11):5064-6. doi: 10.1158/ 0008-5472.CAN-07-0912.
    • (2007) Cancer Res , vol.67 , Issue.11 , pp. 5064-5066
    • Lin, E.Y.1    Pollard, J.W.2
  • 91
    • 42349091268 scopus 로고    scopus 로고
    • Breast carcinoma-associated fibroblasts and their counterparts display neoplastic-specific changes
    • doi: 10.1158/0008-5472.CAN-08-0192
    • Hawsawi NM, Ghebeh H, Hendrayani SF, Tulbah A, Al-Eid M, Al-Tweigeri T, et al. Breast carcinoma-associated fibroblasts and their counterparts display neoplastic-specific changes. Cancer Res. 2008;68(8):2717-25. doi: 10.1158/0008-5472.CAN-08-0192.
    • (2008) Cancer Res , vol.68 , Issue.8 , pp. 2717-2725
    • Hawsawi, N.M.1    Ghebeh, H.2    Hendrayani, S.F.3    Tulbah, A.4    Al-Eid, M.5    Al-Tweigeri, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.