Promiscuous modification of the nuclear poly(A)-binding protein by multiple protein-arginine methyltransferases does not affect the aggregation behavior

Journal of Biological Chemistry

Volumn 283, Issue 29, 2008, Pages 20408-20420

  Fronz, Katharina ^a   Otto, Silke ^a   Kölbel, Knut ^a   Kühn, Uwe ^a   Friedrich, Henning ^a   Schierhorn, Angelika ^a   Beck Sickinger, Annette G ^b   Ostareck Lederer, Antje ^a   Wahle, Elmar ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; AMINATION; AMINES; ASSOCIATION REACTIONS; CELL CULTURE; ENZYMES; MAMMALS; METHYLATION; ORGANIC ACIDS; PLANTS (BOTANY); PORT TERMINALS; PROTEINS; SUBSTRATES;

AGGREGATION BEHAVIORS; AMINO ACID SEQUENCES; ARGININE RESIDUES; BINDING PROTEINS; CELL EXTRACTS; CELL LINES; DIMETHYLATED ARGININES; DO-MAINS; FUSION PROTEINS; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; METHYL TRANSFERASES; MUSCULAR DYSTROPHIES; ORTHOLOGOUS PROTEINS; SYNTHETIC PEPTIDES; TERMINAL DOMAINS;

AMINO ACIDS;

ARGININE; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; POLYADENYLIC ACID BINDING PROTEIN; POLYADENYLIC ACID BINDING PROTEIN PABPN1; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN ARGININE METHYLTRANSFERASE 1; PROTEIN ARGININE METHYLTRANSFERASE 3; PROTEIN ARGININE METHYLTRANSFERASE 6; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SUBSTRATE; FUNCTIONAL PROTEOMICS; MOLECULAR RECOGNITION; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OCULOPHARYNGEAL MUSCULAR DYSTROPHY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DOMAIN; PROTEIN METHYLATION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; ANIMAL; CATTLE; CELL LINE; CELL NUCLEUS; CYTOPLASM; ENZYME SPECIFICITY; GENETICS; HUMAN; KINETICS; METABOLISM; METHYLATION; MOUSE; MOUSE MUTANT;

BOVINAE; MAMMALIA;

ANIMALS; CATTLE; CELL LINE; CELL NUCLEUS; CYTOPLASM; HUMANS; KINETICS; METHYLATION; MICE; MICE, KNOCKOUT; POLY(A)-BINDING PROTEINS; PROTEIN-ARGININE N-METHYLTRANSFERASE; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 50649114242     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M802329200     Document Type: Article

References (63)

1. Gary, J. D., and Clarke, S. (1998) Prog. Nucleic Acids Res. Mol. Biol. 98, 65-131
2. Bedford, M. T., and Richard, S. (2005) Mol. Cell 18, 263-272
3. Pahlich, S., Zakaryan, R. P., and Gehring, H. (2006) Biochim. Biophys. Acta 1764, 1890-1903
4. Krause, C. D., Yang, Z.-H., Kim, Y.-S., Lee, J.-H., Cook, J. R., and Pestka, S. (2007) Pharmacol. Ther. 113, 50-87
5. Bachand, F. (2007) Eukaryot. Cell 6, 889-898
6. Brahms, H., Raymackers, J., Union, A., de Keyser, F., Meheus, L., and Lührmann, R. (2000) J. Biol. Chem. 275, 17122-17129
7. Côté, J., Boisvert, F.-M., Boulanger, M.-C., Bedford, M. T., and Richard, S. (2003) Mol. Biol. Cell 14, 274-287
8. Ostareck-Lederer, A., Ostareck, D. H., Rucknagel, K. P., Schierhorn, A., Moritz, B., Huttelmaier, S., Flach, N., Handoko, L., and Wahle, E. (2006) J. Biol. Chem. 281, 11115-11125
9. Wang, H., Huang, Z.-Q., Xia, L., Feng, Q., Erdjument-Bromage, H., Strahl, B. D., Briggs, S. D., Allis, C. D., Wong, J., Tempst, P., and Zhang, Y. (2001) Science 293, 853-857
10. Huang, S., Litt, M., and Felsenfeld, G. (2005) Genes Dev. 19, 1885-1893
11. Swiercz, R., Cheng, D., Kim, D., and Bedford, M. T. (2007) J. Biol. Chem. 282, 16917-16923
12. Bachand, F., and Silver, P. A. (2004) EMBO J. 23, 2641-2650
13. Yadav, N., Lee, J., Kim, J., Shen, J., Hu, M. C.-T., Aldaz, C. M., and Bedford, M. T. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 6464-6468
14. Guccione, E., Bassi, C., Casadio, F., Martinato, F., Cesaroni, M., Schuchlautz, H., Lüscher, B., and Amati, B. (2007) Nature 449, 933-937
15. Hyllus, D., Stein, C., Schnabel, K., Schiltz, E., Imhof, A., Dou, Y., Hsieh, J., and Bauer, U.-M. (2007) Genes Dev. 21, 3369-3380
16. Kim, S., Merrill, B. M., Rajpurohit, R., Kumar, A., Stone, K. L., Papov, V. V., Schneiders, J. M., Szer, W., Wilson, S. H., Paik, W. K., and Williams, K. R. (1997) Biochemistry 36, 5185-5192
17. Tang, J., Gary, J. D., Clarke, S., and Herschman, H. R. (1998) J. Biol. Chem. 273, 16935-16945
18. Chen, D., Ma, H., Hong, H., Koh, S. S., Huang, S.-M., Schurter, B. T., Aswad, D. W., and Stallcup, M. R. (1999) Science 284, 2174-2177
19. Schurter, B. T., Koh, S. S., Chen, D., Bunick, G. J., Harp, J. M., Hanson, B. L., Henschen-Edman, A., Mackay, D. R., Stallcup, M. R., and Aswad, D. W. (2001) Biochemistry 40, 5747-5756
20. Lee, D. Y., Teyssier, C., Strahl, B. D., and Stallcup, M. R. (2005) Endocr. Rev. 26, 147-170
21. Xu, W., Cho, H., Kadam, S., Banayo, E. M., Anderson, S., Yates, J. R., Emerson, B. M., and Evans, R. M. (2004) Genes Dev. 18, 144-156
22. Friesen, W. J., Paushkin, S., Wyce, A., Massenet, S., Pesiridis, G. S., van Duyne, G., Rappsilber, J., Mann, M., and Dreyfuss, G. (2001) Mol. Cell. Biol. 21, 8289-8300
23. Meister, G., Eggert, C., Bühler, D., Brahms, H., Kambach, C., and Fischer, U. (2001) Curr. Biol. 11, 1990-1994
24. Meister, G., Eggert, C., and Fischer, U. (2002) Trends Cell Biol. 12, 472-478
25. Bear, D. G., Fomproix, N., Soop, T., Björkroth, B., Masich, S., and Daneholt, B. (2003) Exp. Cell Res. 286, 332-344
26. Benoit, B., Mitou, G., Chartier, A., Temme, C., Zaessinger, S., Wahle, E., Busseau, I., and Simonelig, M. (2005) Dev. Cell 9, 511-522
27. Bienroth, S., Keller, W., and Wahle, E. (1993) EMBO J. 12, 585-594
28. Wahle, E. (1991) Cell 66, 759-768
29. Kerwitz, Y., Kühn, U., Lilie, H., Knoth, A., Scheuermann, T., Friedrich, H., Schwarz, E., and Wahle, E. (2003) EMBO J. 22, 3705-3714
30. Wahle, E. (1995) J. Biol. Chem. 270, 2800-2808
31. Nemeth, A., Krause, S., Blank, D., Jenny, A., Jenö, P., Lustig, A., and Wahle, E. (1995) Nucleic Acids Res. 23, 4034-4041
32. Smith, J. J., Rücknagel, K. P., Schierhorn, A., Tang, J., Nemeth, A., Linder, M., Herschman, H. R., and Wahle, E. (1999) J. Biol. Chem. 274, 13229-13234
33. Kühn, U., Nemeth, A., Meyer, S., and Wahle, E. (2003) J. Biol. Chem. 278, 16916-16925
34. Brais, B., Bouchard, J. P., Xie, Y. G., Rochefort, D. L., Chrétien, N., Tomé, F. M. S., Lafrenière, R. G., Rommens, J. M., Uyama, E., Nohira, O., Blumen, S., Korcyn, A. D., Heutink, P., Mathieu, J., Duranceau, A., Codère, F., Fardeau, M., and Rouleau, G. A. (1998) Nat. Genet. 18, 164-167
35. Calado, A., Tomé, F. M. S., Brais, B., Rouleau, G. A., Kühn, U., Wahle, E., and Carmo-Fonseca, M. (2000) Hum. Mol. Genet. 9, 2321-2328
36. Keller, R. W., Kühn, U., Aragon, M., Bornikova, L., Wahle, E., and Bear, D. G. (2000) J. Mol. Biol. 297, 569-583
37. Scheuermann, T., Schulz, B., Blume, A., Wahle, E., Rudolph, R., and Schwarz, E. (2003) Protein Sci. 12, 2685-2692
38. Fan, X., Dion, P., Laganiere, J., Brais, B., and Rouleau, G. A. (2001) Hum. Mol. Genet. 10, 2341-2351
39. Yu, M. C., Bachand, F., McBride, A. E., Komili, S., Casolari, J. M., and Silver, P. A. (2004) Genes Dev. 18, 2924-2935
40. Perreault, A., Lemieux, C., and Bachand, F. (2007) J. Biol. Chem. 282, 7552-7562
41. Verheesen, P., Roussis, A., de Haard, H. J., Groot, A. J., Stam, J. C., den Dunnen, J. T., Frants, R. R., Verkleij, A. J., Verrips, T. C., and van der Maarel, S. M. (2006) Biochim. Biophys. Acta 1764, 1307-1319
42. Zhang, X., and Cheng, X. (2003) Structure (Lond.) 11, 509-520
43. Scorilas, A., Black, M. H., Talieri, M., and Diamandis, E. P. (2000) Biochem. Biophys. Res. Commun. 278, 349-359
44. Tabor, S., and Richardson, C. C. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 1074-1078
45. Wahle, E., Lustig, A., Jenö, P., and Maurer, P. (1993) J. Biol. Chem. 268, 2937-2945
46. Rennert, R., Wespe, C., Beck-Sickinger, A. G., and Neundorf, I. (2006) Biochim. Biophys. Acta 1758, 347-354
47. Krause, S., Fakan, S., Weis, K., and Wahle, E. (1994) Exp. Cell Res. 214, 75-82
48. Lakowski, T. M., and Frankel, A. (2008) J. Biol. Chem. 283, 10015-10025
49. Suckau, E., Resemann, A., Schuerenberg, M., Hufnagel, P., Franzen, J., and Holle, A. (2003) Anal. Bioanal. Chem. 376, 952-965
50. Rüegsegger, U., Beyer, K., and Keller, W. (1996) J. Biol. Chem. 271, 6107-6113
51. Dignam, J. D., Lebovitz, R. M., and Roeder, R. G. (1983) Nucleic Acids Res. 11, 1475-1488
52. Pawlak, M. R., Scherer, C. A., Chen, J., Roshon, M. J., and Ruley, H. E. (2000) Mol. Cell. Biol. 20, 4859-4869
53. Lee, J., Sayegh, J., Daniel, J., Clarke, S., and Bedford, M. T. (2005) J. Biol. Chem. 280, 32890-32896
54. Lee, J., and Bedford, M. T. (2002) EMBO Rep. 3, 268-273
55. Rappsilber, J., Friesen, W. J., Paushkin, S., Dreyfuss, G., and Mann, M. (2003) Anal. Chem. 75, 3107-3114
56. Tang, J., Frankel, A., Cook, R. J., Kim, S., Paik, W. K., Williams, K. R., Clarke, S., and Herschman, H. R. (2000) J. Biol. Chem. 275, 7723-7730
57. Najbauer, J., Johnson, B. A., Young, A. L., and Aswad, D. W. (1993) J. Biol. Chem. 268, 10501-10509
58. Yue, W. W., Hassler, M., Roe, S. M., Thompson-Vale, V., and Pearl, L. H. (2007) EMBO J. 26, 4402-4412
59. Troffer-Charlier, N., Cura, V., Hassenboehler, P., Moras, D., and Cavarelli, J. (2007) EMBO J. 26, 4391-4401
60. Weiss, V. H., McBride, A. E., Soriano, M. A., Filman, D. J., Silver, P. A., and Hogle, J. M. (2000) Nat. Struct. Biol. 7, 1165-1171
61. Zhang, X., Zhou, L., and Cheng, X. (2000) EMBO J. 19, 3509-3519
62. Osborne, T. C., Obianyo, O., Zhang, X., Cheng, X., and Thompson, P. R. (2007) Biochemistry 46, 13370-13381
63. Pahlich, S., Bschir, K., Chiavi, C., Belyanskaya, L., and Gehring, H. (2005) Proteins 61, 164-175