Inhibition of left ventricular remodelling in spontaneously hypertensive rats by Gαq-protein carboxyl terminus imitation polypeptide GCIP-27 is not entirely dependent on blood pressure

Clinical and Experimental Pharmacology and Physiology

Volumn 35, Issue 10, 2008, Pages 1215-1221

  Wang, Xiu Qin ^a   Zhang, Hai Gang ^a   Cheng, Yi Qun ^a   Li, Xiao Hui ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Blood pressure; G protein; Polypeptide drug; Spontaneously hypertensive rat; Ventricular remodelling

Indexed keywords

COLLAGEN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA Q SUBUNIT CARBOXYL TERMINUS IMITATION POLYPEPTIDE 27; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; LOSARTAN; POLYPEPTIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE REGULATION; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; ECHOCARDIOGRAPHY; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE MASS; HEART VENTRICLE REMODELING; HEART VENTRICLE SEPTUM; MALE; NONHUMAN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE; THICKNESS; TISSUE STRUCTURE; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; WISTAR KYOTO RAT;

ANIMALS; BLOOD PRESSURE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GTP-BINDING PROTEINS; HYPERTENSION; MALE; MOLECULAR MIMICRY; PEPTIDE FRAGMENTS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; VENTRICULAR REMODELING;

EID: 50649107718     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2008.04981.x     Document Type: Article

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