메뉴 건너뛰기




Volumn 92, Issue 7, 2003, Pages 725-731

NFAT transcription factors are critical survival factors that inhibit cardiomyocyte apoptosis during phenylephrine stimulation in vitro

Author keywords

Apoptosis; Calcineurin; Cardiac hypertrophy; NFAT; Phenylephrine

Indexed keywords

CALCINEURIN; CYCLOSPORIN A; PEPTIDE; PHENYLEPHRINE; PROTEIN; PROTEIN VIVIT; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

EID: 0037453589     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000069211.82346.46     Document Type: Article
Times cited : (95)

References (33)
  • 2
    • 0037095815 scopus 로고    scopus 로고
    • Calcineurin and cardiac hypertrophy: Where have we been? Where are we going?
    • Wilkins BJ, Molkentin JD. Calcineurin and cardiac hypertrophy: where have we been? Where are we going? J Physiol. 2002;541:1-8.
    • (2002) J Physiol , vol.541 , pp. 1-8
    • Wilkins, B.J.1    Molkentin, J.D.2
  • 5
    • 0035933370 scopus 로고    scopus 로고
    • Calcineurin pathway is required for endothelin-1-mediated protection against oxidant stress-induced apoptosis in cardiac myocytes
    • Kakita T, Hasegawa K, Iwai-Kanai E, Adachi S, Morimoto T, Wada H, Kawamura T, Yanazume T, Sasayama S. Calcineurin pathway is required for endothelin-1-mediated protection against oxidant stress-induced apoptosis in cardiac myocytes. Circ Res. 2001;88:1239-1246.
    • (2001) Circ Res , vol.88 , pp. 1239-1246
    • Kakita, T.1    Hasegawa, K.2    Iwai-Kanai, E.3    Adachi, S.4    Morimoto, T.5    Wada, H.6    Kawamura, T.7    Yanazume, T.8    Sasayama, S.9
  • 6
    • 0033982992 scopus 로고    scopus 로고
    • Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: An apoptosis-independent model of dilated heart failure
    • De Windt LJ, Lim HW, Taigen T, Wencker D, Condorelli G, Dorn GW 2nd, Kitsis RN, Molkentin JD. Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: an apoptosis-independent model of dilated heart failure. Circ Res. 2000;86:255-263.
    • (2000) Circ Res , vol.86 , pp. 255-263
    • De Windt, L.J.1    Lim, H.W.2    Taigen, T.3    Wencker, D.4    Condorelli, G.5    Dorn G.W. II6    Kitsis, R.N.7    Molkentin, J.D.8
  • 7
    • 0033921549 scopus 로고    scopus 로고
    • Cyclosporin A inhibits cardiac hypertrophy and enhances cardiac dysfunction during postinfarction failure in rats
    • Oie E, Bjornerheim R, Clausen OP, Attramadal H. Cyclosporin A inhibits cardiac hypertrophy and enhances cardiac dysfunction during postinfarction failure in rats. Am J Physiol Heart Circ Physiol. 2000;278:H2115-H2123.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278
    • Oie, E.1    Bjornerheim, R.2    Clausen, O.P.3    Attramadal, H.4
  • 8
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NFAT family: Regulation and function
    • Rao A, Luo C, Hogan PG. Transcription factors of the NFAT family: regulation and function. Annu Rev Immunol. 1997;15:707-747.
    • (1997) Annu Rev Immunol , vol.15 , pp. 707-747
    • Rao, A.1    Luo, C.2    Hogan, P.G.3
  • 9
    • 0035793565 scopus 로고    scopus 로고
    • Ras regulates NFAT3 activity in cardiac myocytes
    • Ichida M, Finkel T. Ras regulates NFAT3 activity in cardiac myocytes. J Biol Chem. 2001;276:3524-3530.
    • (2001) J Biol Chem , vol.276 , pp. 3524-3530
    • Ichida, M.1    Finkel, T.2
  • 12
    • 0036837672 scopus 로고    scopus 로고
    • Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth
    • Wilkins BI, De Windt LJ, Bueno OF, Braz JC, Glascock BJ, Kimball TF, Molkentin JD. Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth. Mol Cell Biol. 2002;22:7603-7613.
    • (2002) Mol Cell Biol , vol.22 , pp. 7603-7613
    • Wilkins, B.I.1    De Windt, L.J.2    Bueno, O.F.3    Braz, J.C.4    Glascock, B.J.5    Kimball, T.F.6    Molkentin, J.D.7
  • 13
    • 0032849010 scopus 로고    scopus 로고
    • Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A
    • Aramburu J, Yaffe MB, Lopez-Rodriguez C, Cantley LC, Hogan PG, Rao A. Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A. Science. 1999;285:2129-2133.
    • (1999) Science , vol.285 , pp. 2129-2133
    • Aramburu, J.1    Yaffe, M.B.2    Lopez-Rodriguez, C.3    Cantley, L.C.4    Hogan, P.G.5    Rao, A.6
  • 14
    • 0030974118 scopus 로고    scopus 로고
    • Dual role of the nuclear factor of activated T cells insert region in DNA recognition and cooperative contacts to activator protein 1
    • Sun LJ, Peterson BR, Verdine GL. Dual role of the nuclear factor of activated T cells insert region in DNA recognition and cooperative contacts to activator protein 1. Proc Natl Acad Sci USA. 1997;94:4919-4924.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4919-4924
    • Sun, L.J.1    Peterson, B.R.2    Verdine, G.L.3
  • 15
    • 0031297248 scopus 로고    scopus 로고
    • δ-opioid receptors expressed by Jurkat T cells enhance IL-2 secretion by increasing AP-1 complexes and activity of the NF-AT/AP-1-binding promoter element
    • Hedin KE, Bell MP, Kalli KR, Huntoon CJ, Sharp BM, McKean DJ. δ-Opioid receptors expressed by Jurkat T cells enhance IL-2 secretion by increasing AP-1 complexes and activity of the NF-AT/AP-1-binding promoter element. J Immunol. 1997;159:5431-5440.
    • (1997) J Immunol , vol.159 , pp. 5431-5440
    • Hedin, K.E.1    Bell, M.P.2    Kalli, K.R.3    Huntoon, C.J.4    Sharp, B.M.5    McKean, D.J.6
  • 16
    • 0034177057 scopus 로고    scopus 로고
    • Specific role of the extracellular signal-regulated kinase pathway in angiotensin II-induced cardiac hypertrophy in vitro
    • Aoki H, Richmond M, Izumo S, Sadoshima J. Specific role of the extracellular signal-regulated kinase pathway in angiotensin II-induced cardiac hypertrophy in vitro. Biochem J. 2000;347:275-284.
    • (2000) Biochem J , vol.347 , pp. 275-284
    • Aoki, H.1    Richmond, M.2    Izumo, S.3    Sadoshima, J.4
  • 18
    • 0030913673 scopus 로고    scopus 로고
    • Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
    • Khwaja A, Rodriguez-Viciana P, Wennstrom S, Warne PH. Downward J. Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J. 1997;16:2783-2793.
    • (1997) EMBO J , vol.16 , pp. 2783-2793
    • Khwaja, A.1    Rodriguez-Viciana, P.2    Wennstrom, S.3    Warne, P.H.4    Downward, J.5
  • 19
    • 0033981108 scopus 로고    scopus 로고
    • Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy
    • Taigen T, De Windt LJ, Lim HW, Molkentin JD. Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy. Proc Natl Acad Sci U S A. 2000;97:1196-1201.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1196-1201
    • Taigen, T.1    De Windt, L.J.2    Lim, H.W.3    Molkentin, J.D.4
  • 23
    • 0034623814 scopus 로고    scopus 로고
    • Cardiomyocyte apoptosis induced by Gαq signaling is mediated by permeability transition pore formation and activation of the mitochondrial death pathway
    • Adams JW, Pagel AL, Means CK, Oksenberg D, Armstrong RC, Brown JH. Cardiomyocyte apoptosis induced by Gαq signaling is mediated by permeability transition pore formation and activation of the mitochondrial death pathway. Circ Res. 2000;87:1180-1187.
    • (2000) Circ Res , vol.87 , pp. 1180-1187
    • Adams, J.W.1    Pagel, A.L.2    Means, C.K.3    Oksenberg, D.4    Armstrong, R.C.5    Brown, J.H.6
  • 25
    • 0032561324 scopus 로고    scopus 로고
    • 2+-independent protein kinase C (nPKC) activation and its regulation by calcineurin activation
    • 2+-independent protein kinase C (nPKC) activation and its regulation by calcineurin activation. J Biol Chem. 1998;273:28392-28398.
    • (1998) J Biol Chem , vol.273 , pp. 28392-28398
    • Asada, A.1    Zhao, Y.2    Kondo, S.3    Iwata, M.4
  • 27
    • 0034008511 scopus 로고    scopus 로고
    • Calcineurin is downstream of the inositol 1,4,5-trisphosphate receptor in the apoptotic and cell growth pathways
    • Jayaraman T, Marks AR. Calcineurin is downstream of the inositol 1,4,5-trisphosphate receptor in the apoptotic and cell growth pathways. J Biol Chem. 2000;275:6417-6420.
    • (2000) J Biol Chem , vol.275 , pp. 6417-6420
    • Jayaraman, T.1    Marks, A.R.2
  • 28
    • 0029061299 scopus 로고
    • Calcineurin activation protects T cells from glucocorticoid-induced apoptosis
    • Zhao Y, Tozawa Y, Iseki R, Mukai M, Iwata M. Calcineurin activation protects T cells from glucocorticoid-induced apoptosis. J Immunol. 1995;154:6346-6354.
    • (1995) J Immunol , vol.154 , pp. 6346-6354
    • Zhao, Y.1    Tozawa, Y.2    Iseki, R.3    Mukai, M.4    Iwata, M.5
  • 29
    • 0032742696 scopus 로고    scopus 로고
    • Suppression or induction of apoptosis by opposing pathways downstream from calcium-activated calcineurin
    • Lotem J, Kama R, Sachs L. Suppression or induction of apoptosis by opposing pathways downstream from calcium-activated calcineurin. Proc Natl Acad Sci U S A. 1999;96:12016-12020.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 12016-12020
    • Lotem, J.1    Kama, R.2    Sachs, L.3
  • 30
    • 0034614611 scopus 로고    scopus 로고
    • 2+-dependent gene expression mediated by MEF2 transcription factors
    • 2+-dependent gene expression mediated by MEF2 transcription factors. J Biol Chem. 2000;275:197-209.
    • (2000) J Biol Chem , vol.275 , pp. 197-209
    • Blaeser, F.1    Ho, N.2    Prywes, R.3    Chatila, T.A.4
  • 31
    • 0036094148 scopus 로고    scopus 로고
    • Phosphorylation of NFATc4 by p38 mitogen-activated protein kinases
    • Yang TT, Xiong Q, Enslen H, Davis RJ, Chow CW. Phosphorylation of NFATc4 by p38 mitogen-activated protein kinases. Mol Cell Biol. 2002;22:3892-3904.
    • (2002) Mol Cell Biol , vol.22 , pp. 3892-3904
    • Yang, T.T.1    Xiong, Q.2    Enslen, H.3    Davis, R.J.4    Chow, C.W.5
  • 33
    • 0034721924 scopus 로고    scopus 로고
    • Calcineurin and beyond: Cardiac hypertrophic signaling
    • Molkentin JD. Calcineurin and beyond: cardiac hypertrophic signaling. Circ Res. 2000;87:731-738.
    • (2000) Circ Res , vol.87 , pp. 731-738
    • Molkentin, J.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.