CD4+ T cell help improves CD8+ T cell memory by retained CD27 expression

European Journal of Immunology

Volumn 38, Issue 7, 2008, Pages 1847-1856

  Matter, Matthias S ^a,b   Claus, Christina ^a   Ochsenbein, Adrian F ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

CD27; CD4 T cell help; Costimulation; LCMV; T cell memory

Indexed keywords

CD27 ANTIGEN; CD70 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; AUTOCRINE EFFECT; C57BL 6 MOUSE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; HELPER CELL; IMMUNE RESPONSE; IMMUNOSTIMULATION; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; T CELL DEPLETION; T LYMPHOCYTE ACTIVATION; VIRUS LOAD; ANIMAL; C57BL MOUSE; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; SIGNAL TRANSDUCTION; VIRUS INFECTION;

ANIMALS; ANTIGENS, CD27; ARENAVIRIDAE INFECTIONS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; IMMUNOLOGIC MEMORY; INTERLEUKIN-2; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SIGNAL TRANSDUCTION;

EID: 50549083200     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200737824     Document Type: Article

References (47)

1. + T cell differentiation: Initial antigen encounter triggers a developmental program in naive cells. Nat. Immunol. 2001. 2: 415-422.
2. van Stipdonk, M. J., Lemmens, E. E. and Schoenberger, S. P., Naive CTL require a single brief period of antigenic stimulation for clonal expansion and differentiation. Nat. Immunol. 2001. 2: 423-429.
3. Badovinac, V. P., Porter, B. B. and Harty, J. T., Programmed contraction of CD8(+) T cells after infection. Nat. Immunol. 2002. 3: 619-626.
4. Sun, J. C. and Bevan, M. J., Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 2003. 300: 339-342.
5. Shedlock, D. J. and Shen, H., Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 2003. 300: 337-339.
6. + T lymphocytes. Nature 2003. 421: 852-856.
7. + T cell memory. Science 2002. 297: 2060-2063.
8. + T-cell memory via TRAIL-mediated activation-induced cell death. Nature 2005. 434: 88-93.
9. Schoenberger, S. P., Toes, R. E., van der Voort, E. I., Offringa, R. and Melief, C. J., T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature 1998. 393: 480-483.
10. + T-helper and a T-killer cell. Nature 1998. 393: 474-478.
11. Bennett, S. R., Carbone, F. R., Karamalis, F., Flavell, R. A.,Miller, J. F. and Heath, W. R., Help for cytotoxic-T-cell responses is mediated by CD40 signaling. Nature 1998. 393: 478-480.
12. Taraban, V. Y., Rowley, T. F. and Al-Shamkhani, A., Cutting edge: a critical role for CD70 in CD8 T cell priming by CD40-licensed APCs. J. Immunol. 2004. 173: 6542-6546.
13. + T-cell responses against malaria liver stages. Nat.Med. 2002. 8: 166-170.
14. + memory T cells. Nature 2006. 441: 890-893.
15. + T cells differentiate into protective memory-like cells after IL-2 anti IL-2 complex treatment in vivo. J. Exp. Med. 2007. 204: 1803-1812.
16. + T cell responses in acute and chronic viral infections. Eur. J. Immunol. 2007. 37: 1502-1512.
17. Sallusto, F., Lenig, D., Forster, R., Lipp, M. and Lanzavecchia, A., Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999. 401: 708-712.
18. + T cells. J. Exp. Med. 2007. 204: 1625-1636.
19. Appay, V., Dunbar, P. R., Callan, M., Klenerman, P., Gillespie, G. M., Papagno, L., Ogg, G. S. et al., Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections. Nat. Med. 2002. 8: 379-385.
20. + T cells. J. Exp. Med. 1997. 186: 1407-1418.
21. Wherry, E. J., Teichgraber, V., Becker, T. C., Masopust, D., Kaech, S. M., Antia, R., von Andrian, U. H. and Ahmed, R., Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat. Immunol. 2003. 4: 225-234.
22. Croft, M., Co-stimulatory members of the TNFR family: Keys to effective T-cell immunity? Nat. Rev. Immunol. 2003. 3: 609-620.
23. Hintzen, R. Q., Lens, S. M., Lammers, K., Kuiper, H., Beckmann, M. P. and van Lier, R. A., Engagement of CD27 with its ligand CD70 provides a second signal for T cell activation. J. Immunol. 1995. 154: 2612-2623.
24. Hendriks, J., Gravestein, L. A., Tesselaar, K., van Lier, R. A., Schumacher, T. N. and Borst, J., CD27 is required for generation and long-term maintenance of T cell immunity. Nat. Immunol. 2000. 1: 433-440.
25. + cytotoxic T lymphocytes in HIV-infected patients. J. Exp. Med. 2004. 200: 1407-1417.
26. Hendriks, J., Xiao, Y. and Borst, J., CD27 promotes survival of activated T cells and complements CD28 in generation and establishment of the effector T cell pool. J. Exp. Med. 2003. 198: 1369-1380.
27. Arens, R., Tesselaar, K., Baars, P. A., van Schijndel, G. M., Hendriks, J., Pals, S. T., Krimpenfort, P. et al., Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFN-gamma-mediated B cell depletion. Immunity 2001. 15: 801-812.
28. Akiba, H., Nakano, H., Nishinaka, S., Shindo, M., Kobata, T., Atsuta, M., Morimoto, C. et al., CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase. J. Biol. Chem. 1998. 273: 13353-13358.
29. Lieberman, J., Shankar, P., Manjunath, N. and Andersson, J., Dressed to kill? A review of why antiviral CD8 T lymphocytes fail to prevent progressive immunodeficiency in HIV-1 infection. Blood 2001. 98: 1667-1677.
30. + T cells is associated with progression to viral disease in HIV-infection. Aids 2002. 16: 2001-2011.
31. Robbins, P. F., Dudley, M. E., Wunderlich, J., El-Gamil, M., Li, Y. F., Zhou, J., Huang, J. et al., Cutting edge: Persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy. J. Immunol. 2004. 173: 7125-7130.
32. + tumor-reactive effector memory T cells in humans after adoptive cell transfer therapy. Blood 2005. 105: 241-250.
33. Matter, M., Mumprecht, S., Pinschewer, D. D., Pavelic, V., Yagita, H., Krautwald, S., Borst, J. and Ochsenbein, A. F., Virus-induced polyclonal B cell activation improves protective CTL memory via retained CD27 expression on memory CTL. Eur. J. Immunol. 2005. 35: 3229-3239.
34. Planz, O., Ehl, S., Furrer, E., Horvath, E., Brundler, M. A., Hengartner, H. and Zinkernagel, R. M., A critical role for neutralizing-antibody-producing B cells, CD4(+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: Implications for adoptive immunotherapy of virus carriers. Proc. Natl. Acad. Sci. USA 1997. 94: 6874-6879.
35. Bachmann, M. F., Hunziker, L., Zinkernagel, R. M., Storni, T. and Kopf, M., Maintenance of memory CTL responses by T helper cells and CD40-CD40 ligand: Antibodies provide the key. Eur. J. Immunol. 2004. 34: 317-326.
36. + T cell formation. J. Exp. Med. 2004. 199: 1595-1605.
37. Oshima, H., Nakano, H., Nohara, C., Kobata, T., Nakajima, A., Jenkins, N. A., Gilbert, D. J. et al., Characterization of murine CD70 by molecular cloning and mAb. Int. Immunol. 1998. 10: 517-526.
38. Hase, H., Kanno, Y., Kojima, H., Morimoto, C., Okumura, K. and Kobata, T., CD27 and CD40 inhibit p53-independent mitochondrial pathways in apoptosis of B cells induced by B cell receptor ligation. J. Biol. Chem. 2002. 277: 46950-46958.
39. Benczik, M. and Gaffen, S. L., The interleukin (IL)-2 family cytokines: Survival and proliferation signaling pathways in T lymphocytes. Immunol. Invest. 2004. 33: 109-142.
40. + T cell without effector differentiation. Proc. Natl. Acad. Sci. USA 2006. 103: 19454-19459.
41. Orengo, A. M., Cantoni, C., Neglia, F., Biassoni, R. and Ferrini, S., Reciprocal expression of CD70 and of its receptor, CD27, in human long term-activated T and natural killer (NK) cells: Inverse regulation by cytokines and role in induction of cytotoxicity. Clin. Exp. Immunol. 1997. 107: 608-613.
42. de Jong, R., Loenen, W. A., Brouwer, M., van Emmerik, L., de Vries, E. F., Borst, J. and van Lier, R. A., Regulation of expression of CD27, a T cell-specific member of a novel family of membrane receptors. J. Immunol. 1991. 146: 2488-2494.
43. Hintzen, R. Q., Lens, S. M., Beckmann, M. P., Goodwin, R. G., Lynch, D. and van Lier, R. A.W., Characterization of the human CD27 ligand, a novel member of the TNF gene family. J. Immunol. 1994. 1762-1773.
44. Schildknecht, A., Miescher, I., Yagita, H. and van den Broek, M., Priming of CD8+ T cell responses by pathogens typically depends on CD70-mediated interactions with dendritic cells. Eur. J. Immunol. 2007. 37: 716-728.
45. Badovinac, V. P., Messingham, K. A., Griffith, T. S. and Harty, J. T., TRAIL deficiency delays, but does not prevent, erosion in the quality of "helpless" memory CD8 T cells. J. Immunol. 2006. 177: 999-1006.
46. Pircher, H., Bürki, K., Lang, R., Hengartner, H. and Zinkernagel, R. M., Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature 1989. 342: 559-561.
47. Bergthaler, A., Merkler, D., Horvath, E., Bestmann, L. and Pinschewer, D. D., Contributions of the lymphocytic choriomeningitis virus glycoprotein and polymerase to strain-specific differences in murine liver pathogenicity. J. Gen. Virol. 2007. 88: 592-603.