메뉴 건너뛰기




Volumn 68, Issue 5, 2008, Pages 393-401

The reduced folate carrier (RFC1) 80G>A and folate hydrolase 1 (FOLH1) 1561C>T polymorphisms and the risk of colorectal cancer: A nested case-referent study

Author keywords

Colon; Homocysteine; Neoplasms; Rectum; Risk factors; Serum folate level; Single nucleotide polymorphisms; Sweden

Indexed keywords

GAMMA GLUTAMYL HYDROLASE; GAMMA GLUTAMYL HYDROLASE 1; HOMOCYSTEINE; REDUCED FOLATE CARRIER; UNCLASSIFIED DRUG;

EID: 50449089655     PISSN: 00365513     EISSN: 15027686     Source Type: Journal    
DOI: 10.1080/00365510701805431     Document Type: Article
Times cited : (18)

References (45)
  • 1
  • 2
    • 30344479948 scopus 로고    scopus 로고
    • Folate, vitamin B6, multivitamin supplements, and colorectal cancer risk in women
    • Zhang SM, Moore SC, Lin J, Cook NR, Manson JE, Lee IM, et al. Folate, vitamin B6, multivitamin supplements, and colorectal cancer risk in women. Am J Epidemiol 2006;163:108-15.
    • (2006) Am J Epidemiol , vol.163 , pp. 108-115
    • Zhang, S.M.1    Moore, S.C.2    Lin, J.3    Cook, N.R.4    Manson, J.E.5    Lee, I.M.6
  • 3
    • 16844376922 scopus 로고    scopus 로고
    • A prospective study of dietary folate intake and risk of colorectal cancer: Modification by caffeine intake and cigarette smoking
    • Larsson SC, Giovannucci E, Wolk A. A prospective study of dietary folate intake and risk of colorectal cancer: modification by caffeine intake and cigarette smoking. Cancer Epidemiol Biomarkers Prev 2005;14:740-3.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 740-743
    • Larsson, S.C.1    Giovannucci, E.2    Wolk, A.3
  • 6
    • 0036784440 scopus 로고    scopus 로고
    • Intake of dietary folate vitamers and risk of colorectal carcinoma: Results from The Netherlands Cohort Study
    • Konings EJ, Goldbohm RA, Brants HA, Saris WH, van den Brandt PA. Intake of dietary folate vitamers and risk of colorectal carcinoma: results from The Netherlands Cohort Study. Cancer 2002;95:1421-33.
    • (2002) Cancer , vol.95 , pp. 1421-1433
    • Konings, E.J.1    Goldbohm, R.A.2    Brants, H.A.3    Saris, W.H.4    van den Brandt, P.A.5
  • 7
    • 0035174804 scopus 로고    scopus 로고
    • Nutritional status of folate and colon cancer risk: Evidence from NHANES I epidemiologic follow-up study
    • Su LJ, Arab L. Nutritional status of folate and colon cancer risk: evidence from NHANES I epidemiologic follow-up study. Ann Epidemiol 2001;11:65-72.
    • (2001) Ann Epidemiol , vol.11 , pp. 65-72
    • Su, L.J.1    Arab, L.2
  • 8
    • 0032999331 scopus 로고    scopus 로고
    • Serum folate, homocysteine and colorectal cancer risk in women: A nested case-control study
    • Kato I, Dnistrian AM, Schwartz M, Toniolo P, Koenig K, Shore RE, et al. Serum folate, homocysteine and colorectal cancer risk in women: a nested case-control study. Br J Cancer 1999;79:1917-22.
    • (1999) Br J Cancer , vol.79 , pp. 1917-1922
    • Kato, I.1    Dnistrian, A.M.2    Schwartz, M.3    Toniolo, P.4    Koenig, K.5    Shore, R.E.6
  • 10
    • 0030615085 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer
    • Ma J, Stampfer MJ, Giovannucci E, Artigas C, Hunter DJ, Fuchs C, et al. Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer. Cancer Res 1997;57:1098-102.
    • (1997) Cancer Res , vol.57 , pp. 1098-1102
    • Ma, J.1    Stampfer, M.J.2    Giovannucci, E.3    Artigas, C.4    Hunter, D.J.5    Fuchs, C.6
  • 11
    • 32944467170 scopus 로고    scopus 로고
    • Folate levels and cancer morbidity and mortality: Prospective cohort study from Busselton, Western Australia
    • Rossi E, Hung J, Beilby JP, Knuiman MW, Divitini ML, Bartholomew H. Folate levels and cancer morbidity and mortality: prospective cohort study from Busselton, Western Australia. Ann Epidemiol 2006;16:206-12.
    • (2006) Ann Epidemiol , vol.16 , pp. 206-212
    • Rossi, E.1    Hung, J.2    Beilby, J.P.3    Knuiman, M.W.4    Divitini, M.L.5    Bartholomew, H.6
  • 15
    • 33645753544 scopus 로고    scopus 로고
    • Homocysteine lowering with folic acid and B vitamins in vascular disease
    • Lonn E, Yusuf S, Arnold MJ, Sheridan P, Pogue J, Micks M, et al. Homocysteine lowering with folic acid and B vitamins in vascular disease. N Engl J Med 2006;354:1567-77.
    • (2006) N Engl J Med , vol.354 , pp. 1567-1577
    • Lonn, E.1    Yusuf, S.2    Arnold, M.J.3    Sheridan, P.4    Pogue, J.5    Micks, M.6
  • 17
    • 16544370325 scopus 로고    scopus 로고
    • Will mandatory folic acid fortification prevent or promote cancer?
    • Kim YI. Will mandatory folic acid fortification prevent or promote cancer? Am J Clin Nutr 2004;80:1123-8.
    • (2004) Am J Clin Nutr , vol.80 , pp. 1123-1128
    • Kim, Y.I.1
  • 18
    • 34247589073 scopus 로고    scopus 로고
    • The methylenetetrahydrofolate reductase 677C->T polymorphism as a modulator of a B vitamin network with major effects on homocysteine metabolism
    • Hustad S, Midttun O, Schneede J, Vollset SE, Grotmol T, Ueland PM. The methylenetetrahydrofolate reductase 677C->T polymorphism as a modulator of a B vitamin network with major effects on homocysteine metabolism. Am J Hum Genet 2007;80:846-55.
    • (2007) Am J Hum Genet , vol.80 , pp. 846-855
    • Hustad, S.1    Midttun, O.2    Schneede, J.3    Vollset, S.E.4    Grotmol, T.5    Ueland, P.M.6
  • 20
    • 0033805360 scopus 로고    scopus 로고
    • A polymorphism (80G->A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia
    • Chango A, Emery-Fillon N, de Courcy GP, Lambert D, Pfister M, Rosenblatt DS, et al. A polymorphism (80G->A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia. Mol Genet Metab 2000;70:310-15.
    • (2000) Mol Genet Metab , vol.70 , pp. 310-315
    • Chango, A.1    Emery-Fillon, N.2    de Courcy, G.P.3    Lambert, D.4    Pfister, M.5    Rosenblatt, D.S.6
  • 21
    • 0035187308 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in the human reduced folate carrier: Characterization of a high-frequency G/A variant at position 80 and transport properties of the His(27) and Arg(27) carriers
    • Whetstine JR, Gifford AJ, Witt T, Liu XY, Flatley RM, Norris M, et al. Single nucleotide polymorphisms in the human reduced folate carrier: characterization of a high-frequency G/A variant at position 80 and transport properties of the His(27) and Arg(27) carriers. Clin Cancer Res 2001;7:3416-22.
    • (2001) Clin Cancer Res , vol.7 , pp. 3416-3422
    • Whetstine, J.R.1    Gifford, A.J.2    Witt, T.3    Liu, X.Y.4    Flatley, R.M.5    Norris, M.6
  • 22
    • 33645635701 scopus 로고    scopus 로고
    • Interactions among polymorphisms in folate-metabolizing genes and serum total homocysteine concentrations in a healthy elderly population
    • Devlin AM, Clarke R, Birks J, Evans JG, Halsted CH. Interactions among polymorphisms in folate-metabolizing genes and serum total homocysteine concentrations in a healthy elderly population. Am J Clin Nutr 2006;83:708-13.
    • (2006) Am J Clin Nutr , vol.83 , pp. 708-713
    • Devlin, A.M.1    Clarke, R.2    Birks, J.3    Evans, J.G.4    Halsted, C.H.5
  • 23
    • 33746130404 scopus 로고    scopus 로고
    • G80A reduced folate carrier SNP influences the absorption and cellular translocation of dietary folate and its association with blood pressure in an elderly population
    • Dufficy L, Naumovski N, Ng X, Blades B, Yates Z, Travers C, et al. G80A reduced folate carrier SNP influences the absorption and cellular translocation of dietary folate and its association with blood pressure in an elderly population. Life Sci 2006;79:957-66.
    • (2006) Life Sci , vol.79 , pp. 957-966
    • Dufficy, L.1    Naumovski, N.2    Ng, X.3    Blades, B.4    Yates, Z.5    Travers, C.6
  • 24
    • 24744443273 scopus 로고    scopus 로고
    • G80A reduced folate carrier SNP modulates cellular uptake of folate and affords protection against thrombosis via a non-homocysteine related mechanism
    • Yates Z, Lucock M. G80A reduced folate carrier SNP modulates cellular uptake of folate and affords protection against thrombosis via a non-homocysteine related mechanism. Life Sci 2005;77:2735-42.
    • (2005) Life Sci , vol.77 , pp. 2735-2742
    • Yates, Z.1    Lucock, M.2
  • 25
    • 6944248069 scopus 로고    scopus 로고
    • Plasma folate as marker of folate status in epidemiological studies: The European Investigation into Cancer and Nutrition (EPIC) - Potsdam study
    • Drogan D, Klipstein-Grobusch K, Wans S, Luley C, Boeing H, Dierkes J. Plasma folate as marker of folate status in epidemiological studies: the European Investigation into Cancer and Nutrition (EPIC) - Potsdam study. Br J Nutr 2004;92:489-96.
    • (2004) Br J Nutr , vol.92 , pp. 489-496
    • Drogan, D.1    Klipstein-Grobusch, K.2    Wans, S.3    Luley, C.4    Boeing, H.5    Dierkes, J.6
  • 26
    • 1842418757 scopus 로고    scopus 로고
    • Low erythrocyte folate status and polymorphic variation in folate-related genes are associated with risk of neural tube defect pregnancy
    • Relton CL, Wilding CS, Laffling AJ, Jonas PA, Burgess T, Binks K, et al. Low erythrocyte folate status and polymorphic variation in folate-related genes are associated with risk of neural tube defect pregnancy. Mol Genet Metab 2004;81:273-81.
    • (2004) Mol Genet Metab , vol.81 , pp. 273-281
    • Relton, C.L.1    Wilding, C.S.2    Laffling, A.J.3    Jonas, P.A.4    Burgess, T.5    Binks, K.6
  • 27
    • 0037677623 scopus 로고    scopus 로고
    • Evaluation of genetic variants in the reduced folate carrier and in glutamate carboxypeptidase II for spina bifida risk
    • Morin I, Devlin AM, Leclerc D, Sabbaghian N, Halsted CH, Finnell R, et al. Evaluation of genetic variants in the reduced folate carrier and in glutamate carboxypeptidase II for spina bifida risk. Mol Genet Metab 2003;79:197-200.
    • (2003) Mol Genet Metab , vol.79 , pp. 197-200
    • Morin, I.1    Devlin, A.M.2    Leclerc, D.3    Sabbaghian, N.4    Halsted, C.H.5    Finnell, R.6
  • 28
    • 0037513238 scopus 로고    scopus 로고
    • Effects of the glutamate carboxypeptidase II (GCP2 1561C>T) and reduced folate carrier (RFC1 80G>A) allelic variants on folate and total homocysteine levels in kidney transplant patients
    • Winkelmayer WC, Eberle C, Sunder-Plassmann G, Fodinger M. Effects of the glutamate carboxypeptidase II (GCP2 1561C>T) and reduced folate carrier (RFC1 80G>A) allelic variants on folate and total homocysteine levels in kidney transplant patients. Kidney Int 2003;63:2280-5.
    • (2003) Kidney Int , vol.63 , pp. 2280-2285
    • Winkelmayer, W.C.1    Eberle, C.2    Sunder-Plassmann, G.3    Fodinger, M.4
  • 29
    • 28644446615 scopus 로고    scopus 로고
    • Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer
    • Ulrich CM, Curtin K, Potter JD, Bigler J, Caan B, Slattery ML. Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer. Cancer Epidemiol Biomarkers Prev 2005;14:2509-16.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 2509-2516
    • Ulrich, C.M.1    Curtin, K.2    Potter, J.D.3    Bigler, J.4    Caan, B.5    Slattery, M.L.6
  • 30
    • 0034703861 scopus 로고    scopus 로고
    • Glutamate carboxypeptidase II: A polymorphism associated with lower levels of serum folate and hyperhomocysteinemia
    • Devlin AM, Ling EH, Peerson JM, Fernando S, Clarke R, Smith AD, et al. Glutamate carboxypeptidase II: a polymorphism associated with lower levels of serum folate and hyperhomocysteinemia. Hum Mol Genet 2000;9:2837-44.
    • (2000) Hum Mol Genet , vol.9 , pp. 2837-2844
    • Devlin, A.M.1    Ling, E.H.2    Peerson, J.M.3    Fernando, S.4    Clarke, R.5    Smith, A.D.6
  • 31
    • 34547869292 scopus 로고    scopus 로고
    • Relations of glutamate carboxypeptidase II (GCPII) polymorphisms to folate and homocysteine concentrations and to scores of cognition, anxiety, and depression in a homogeneous Norwegian population: The Hordaland Homocysteine Study
    • Halsted CH, Wong DH, Peerson JM, Warden CH, Refsum H, Smith AD, et al. Relations of glutamate carboxypeptidase II (GCPII) polymorphisms to folate and homocysteine concentrations and to scores of cognition, anxiety, and depression in a homogeneous Norwegian population: the Hordaland Homocysteine Study. Am J Clin Nutr 2007;86:514-21.
    • (2007) Am J Clin Nutr , vol.86 , pp. 514-521
    • Halsted, C.H.1    Wong, D.H.2    Peerson, J.M.3    Warden, C.H.4    Refsum, H.5    Smith, A.D.6
  • 32
    • 2442681816 scopus 로고    scopus 로고
    • Polymorphisms in the one-carbon metabolic pathway, plasma folate levels and colorectal cancer in a prospective study
    • Chen J, Kyte C, Valcin M, Chan W, Wetmur JG, Selhub J, et al. Polymorphisms in the one-carbon metabolic pathway, plasma folate levels and colorectal cancer in a prospective study. Int J Cancer 2004;110:617-20.
    • (2004) Int J Cancer , vol.110 , pp. 617-620
    • Chen, J.1    Kyte, C.2    Valcin, M.3    Chan, W.4    Wetmur, J.G.5    Selhub, J.6
  • 33
    • 4544260571 scopus 로고    scopus 로고
    • Bioavailability of polyglutamyl folic acid relative to that of monoglutamyl folic acid in subjects with different genotypes of the glutamate carboxypeptidase II gene
    • Melse-Boonstra A, Lievers KJ, Blom HJ, Verhoef P. Bioavailability of polyglutamyl folic acid relative to that of monoglutamyl folic acid in subjects with different genotypes of the glutamate carboxypeptidase II gene. Am J Clin Nutr 2004;80:700-4.
    • (2004) Am J Clin Nutr , vol.80 , pp. 700-704
    • Melse-Boonstra, A.1    Lievers, K.J.2    Blom, H.J.3    Verhoef, P.4
  • 34
    • 0037224868 scopus 로고    scopus 로고
    • The H475Y polymorphism in the glutamate carboxypeptidase II gene increases plasma folate without affecting the risk for neural tube defects in humans
    • Afman LA, Trijbels FJ, Blom HJ. The H475Y polymorphism in the glutamate carboxypeptidase II gene increases plasma folate without affecting the risk for neural tube defects in humans. J Nutr 2003;133:75-7.
    • (2003) J Nutr , vol.133 , pp. 75-77
    • Afman, L.A.1    Trijbels, F.J.2    Blom, H.J.3
  • 35
    • 0036801570 scopus 로고    scopus 로고
    • Influence of a glutamate carboxypeptidase II (GCPII) polymorphism (1561C->T) on plasma homocysteine, folate and vitamin B(12) levels and its relationship to cardiovascular disease risk
    • Lievers KJ, Kluijtmans LA, Boers GH, Verhoef P, den Heijer M, Trijbels FJ, et al. Influence of a glutamate carboxypeptidase II (GCPII) polymorphism (1561C->T) on plasma homocysteine, folate and vitamin B(12) levels and its relationship to cardiovascular disease risk. Atherosclerosis 2002;164:269-73.
    • (2002) Atherosclerosis , vol.164 , pp. 269-273
    • Lievers, K.J.1    Kluijtmans, L.A.2    Boers, G.H.3    Verhoef, P.4    den Heijer, M.5    Trijbels, F.J.6
  • 36
    • 0036276029 scopus 로고    scopus 로고
    • The glutamate carboxypeptidase gene II (C>T) polymorphism does not affect folate status in the Framingham Offspring cohort
    • Vargas-Martinez C, Ordovas JM, Wilson PW, Selhub J. The glutamate carboxypeptidase gene II (C>T) polymorphism does not affect folate status in the Framingham Offspring cohort. J Nutr 2002;132:1176-9.
    • (2002) J Nutr , vol.132 , pp. 1176-1179
    • Vargas-Martinez, C.1    Ordovas, J.M.2    Wilson, P.W.3    Selhub, J.4
  • 38
    • 2442547553 scopus 로고    scopus 로고
    • Cardiovascular disease and diabetes in the Northern Sweden Health and Disease Study Cohort - evaluation of risk factors and their interactions
    • Hallmans G, Agren A, Johansson G, Johansson A, Stegmayr B, Jansson JH, et al. Cardiovascular disease and diabetes in the Northern Sweden Health and Disease Study Cohort - evaluation of risk factors and their interactions. Scand J Public Health 2003;Suppl 61:18-24.
    • (2003) Scand J Public Health , Issue.SUPPL. 61 , pp. 18-24
    • Hallmans, G.1    Agren, A.2    Johansson, G.3    Johansson, A.4    Stegmayr, B.5    Jansson, J.H.6
  • 39
    • 33845192993 scopus 로고    scopus 로고
    • Reduced folate carrier gene G80A polymorphism is associated with an increased risk of gastroesophageal cancers in a Chinese population
    • Wang L, Chen W, Wang J, Tan Y, Zhou Y, Ding W, et al. Reduced folate carrier gene G80A polymorphism is associated with an increased risk of gastroesophageal cancers in a Chinese population. Eur J Cancer 2006;42:3206-11.
    • (2006) Eur J Cancer , vol.42 , pp. 3206-3211
    • Wang, L.1    Chen, W.2    Wang, J.3    Tan, Y.4    Zhou, Y.5    Ding, W.6
  • 40
    • 34247599285 scopus 로고    scopus 로고
    • Gene polymorphisms of folate metabolizing enzymes and the risk of gastric cancer
    • Gotze T, Rocken C, Rohl FW, Wex T, Hoffmann J, Westphal S, et al. Gene polymorphisms of folate metabolizing enzymes and the risk of gastric cancer. Cancer Lett 2007;251:228-36.
    • (2007) Cancer Lett , vol.251 , pp. 228-236
    • Gotze, T.1    Rocken, C.2    Rohl, F.W.3    Wex, T.4    Hoffmann, J.5    Westphal, S.6
  • 41
    • 4744344223 scopus 로고    scopus 로고
    • Clearing up the confusion over the glutamate carboxypeptidase II gene
    • author reply 329-30
    • O'Keefe DS, Heston WD. Clearing up the confusion over the glutamate carboxypeptidase II gene. Am J Med Genet 2004;130 A:327-28; author reply 329-30.
    • (2004) Am J Med Genet , vol.130 , Issue.A , pp. 327-328
    • O'Keefe, D.S.1    Heston, W.D.2
  • 42
    • 4744365205 scopus 로고    scopus 로고
    • Glutamate carboxipeptidase II (GCPII) His475Tyr polymorphism and association studies
    • Vieira AR, Devlin AM. Glutamate carboxipeptidase II (GCPII) His475Tyr polymorphism and association studies. Am J Med Genet 2004;130A:329-30.
    • (2004) Am J Med Genet , vol.130 A , pp. 329-330
    • Vieira, A.R.1    Devlin, A.M.2
  • 43
    • 0031716221 scopus 로고    scopus 로고
    • Colonic mucosal concentrations of folate correlate well with blood measurements of folate status in persons with colorectal polyps
    • Kim YI, Fawaz K, Knox T, Lee YM, Norton R, Arora S, et al. Colonic mucosal concentrations of folate correlate well with blood measurements of folate status in persons with colorectal polyps. Am J Clin Nutr 1998;68:866-72.
    • (1998) Am J Clin Nutr , vol.68 , pp. 866-872
    • Kim, Y.I.1    Fawaz, K.2    Knox, T.3    Lee, Y.M.4    Norton, R.5    Arora, S.6
  • 44
    • 0034899793 scopus 로고    scopus 로고
    • Colonic mucosal concentrations of folate are accurately predicted by blood measurements of folate status among individuals ingesting physiologic quantities of folate
    • Kim YI, Fawaz K, Knox T, Lee YM, Norton R, Libby E, et al. Colonic mucosal concentrations of folate are accurately predicted by blood measurements of folate status among individuals ingesting physiologic quantities of folate. Cancer Epidemiol Biomarkers Prev 2001;10:715-19.
    • (2001) Cancer Epidemiol Biomarkers Prev , vol.10 , pp. 715-719
    • Kim, Y.I.1    Fawaz, K.2    Knox, T.3    Lee, Y.M.4    Norton, R.5    Libby, E.6
  • 45
    • 0036923084 scopus 로고    scopus 로고
    • Consumption of vegetables, fruit and other plant foods in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohorts from 10 European countries
    • Agudo A, Slimani N, Ocke MC, Naska A, Miller AB, Kroke A, et al. Consumption of vegetables, fruit and other plant foods in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohorts from 10 European countries. Public Health Nutr 2002;5:1179-96.
    • (2002) Public Health Nutr , vol.5 , pp. 1179-1196
    • Agudo, A.1    Slimani, N.2    Ocke, M.C.3    Naska, A.4    Miller, A.B.5    Kroke, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.