Ligand-receptor interactions at the parathyroid hormone receptors: Subtype binding selectivity is mediated via an interaction between residue 23 on the ligand and residue 41 on the receptor

Molecular Pharmacology

Volumn 74, Issue 3, 2008, Pages 605-613

  Mann, Rosalind ^a   Wigglesworth, Mark J ^b   Donnelly, Dan ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; HISTIDINE; ISOLEUCINE; LEUCINE; LIGAND; METHIONINE; PARATHYROID HORMONE; PARATHYROID HORMONE RECEPTOR; PARATHYROID HORMONE RECEPTOR 1; PARATHYROID HORMONE RECEPTOR 2; PARATHYROID HORMONE RELATED PROTEIN; PHENYLALANINE; RECEPTOR SUBTYPE; TRYPTOPHAN; VALINE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; AMINO ACIDS; BINDING, COMPETITIVE; CELL LINE; CELL MEMBRANE; CRYSTALLOGRAPHY, X-RAY; HUMANS; LIGANDS; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, PARATHYROID HORMONE; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 50449087450     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.108.048017     Document Type: Article

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