Homology modeling and dynamics of the extracellular domain of rat and human neuronal nicotinic acetylcholine receptor subtypes α4β2 and α7

Journal of Molecular Modeling

Volumn 14, Issue 10, 2008, Pages 891-899

  Bisson, William H ^a,c   Westera, Gerrit ^a   Schubiger, P Augustus ^a   Scapozza, Leonardo ^b  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Homology modeling; Hydrophobic and electrophilic potentials; Molecular dynamics; Nicotinic acetylcholine receptor; Subtype selectivity

Indexed keywords

ALPHA4 BETA2 NICOTINIC RECEPTOR; BUNGAROTOXIN RECEPTOR; NICOTINIC RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ELECTRIC POTENTIAL; ELECTRON MICROSCOPY; EXTRACELLULAR SPACE; HUMAN; HYDROPHOBICITY; LIGAND BINDING; LIPOPHILICITY; MOLECULAR DYNAMICS; MOLECULAR MODEL; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROCESS DESIGN; PROTEIN CONFORMATION; PROTEIN STABILITY; STRUCTURAL HOMOLOGY; STRUCTURE ANALYSIS; THREE DIMENSIONAL IMAGING;

ANIMALS; BINDING SITES; HUMANS; MODELS, MOLECULAR; NEURONS; RATS; RECEPTORS, NICOTINIC; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

RATTUS;

EID: 50349099254     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-008-0340-x     Document Type: Article

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