Safety evaluation of oligofructose: 13 Week rat study and in vitro mutagenicity

Food and Chemical Toxicology

Volumn 46, Issue 9, 2008, Pages 3132-3139

  Boyle, Frances G ^a   Wrenn, Jacqueline M ^a   Marsh, Billie B ^a   Anderson, Wayne I ^a   Angelosanto, Frank A ^a   McCartney, Anne L ^b   Lien, Eric L ^c  

^a PFIZER INC   (United States)

^b UNIVERSITY OF READING   (United Kingdom)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Ames test; Bifidobacteria; CHO; Oligofructose; Prebiotics; Safety

Indexed keywords

FRUCTOSE OLIGOSACCHARIDE; INULIN; PREBIOTIC AGENT;

AMES TEST; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIFIDOBACTERIUM; CECUM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIETARY INTAKE; EVALUATION; FECES MICROFLORA; FEMALE; HYDROLYSIS; IN SITU HYBRIDIZATION; MALE; MUTAGENICITY; NONHUMAN; ORGAN WEIGHT; RAT; SAFETY; SPRAGUE DAWLEY RAT; WEIGHT GAIN;

ANIMALS; BIFIDOBACTERIUM; BLOOD CHEMICAL ANALYSIS; BODY WEIGHT; CHO CELLS; CHROMOSOME ABERRATIONS; CRICETINAE; CRICETULUS; DIET; DRINKING; EATING; FECES; FEMALE; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MUTAGENICITY TESTS; MUTAGENS; OLIGOSACCHARIDES; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; RATTUS;

EID: 50249149825     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2008.06.079     Document Type: Article

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