Effects of fructo-oligosaccharides ingestion on fecal bifidobacteria and selected metabolic indexes of colon carcinogenesis in healthy humans

Nutrition and Cancer

Volumn 26, Issue 1, 1996, Pages 21-29

  Bouhnik, Yoram ^a   Flourié, Bernard ^a   Riottot, Michel ^b   Bisetti, Nathalie ^c   Gailing, Marie Frédérique ^c   Guibert, Alain ^c   Bornet, Francis ^c   Rambaud, Jean Claude ^a  

^a Hopital Saint Lazare   (France)

^b CNRS   (France)

^c Service Nutrition et Santé   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AZO REDUCTASE; BETA GLUCURONIDASE; BILE ACID; FRUCTOSE OLIGOSACCHARIDE; NITROREDUCTASE; STEROL; SUCROSE;

ADULT; ARTICLE; BACTERIAL COUNT; CLINICAL TRIAL; COLON CANCER; COLON CARCINOGENESIS; COLON FLORA; COLONY FORMING UNIT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ENZYME ACTIVITY; FECES ANALYSIS; FECES MICROFLORA; FEMALE; FERMENTATION; FOOD INTAKE; HUMAN; HUMAN EXPERIMENT; LACTOBACILLUS BIFIDUS; MALE; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL;

EID: 0029817024     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1080/01635589609514459     Document Type: Article

References (38)

1. Hirayama, M, Sumi, N, and Hidaka, H: "Purification and Properties of a Fructo-Oligosaccharides Producing Beta-Fructofuranosidase From Aspergillus niger ATCC 20611." Agric Biol Chem 53, 667-673, 1989.
2. Clevenger, MA, Turnbull, D, Inoue, H, Enomoto, M, Allen, JA, et al.: "Toxicological Evaluation of Neosugar: Genotoxicity, Carcinogenicity and Chronic Toxicology." J Am Coll Toxicol 7, 643-662, 1988.
3. Hidaka, H, Eida, T, Takizawa, T, Tokunaga, T, and Tashiro, Y: "Effects of Fructo-Oligosaccharides on Intestinal Flora and Human Health." Bifidobacteria Microflora 5, 37-50, 1986.
4. Stone-Dorshow, T, and Levitt, MD: "Gaseous Response to Ingestion of a Poorly Absorbed Fructo-Oligosaccharide Sweetener." Am J Clin Nutr 46, 61-65, 1987.
5. 14C] Fructo-Oligosaccharides in Man as Energy Resources." J Clin Biochem Nutr 5, 67-74, 1988.
6. McKellar, RC, and Modker, HW: "Metabolism of Fructo-Oligosaccharides by Bifidobacterium spp." Appl Microbiol Biotechnol 31, 537-541, 1989.
7. Mitsuoka, T, Hidaka, H, and Eida, T: "Effect of Fructo-Oligosaccharides on Intestinal Microflora." Die Nahrung 31, 427-436, 1987.
8. Gibson, GR, and Wang, X: "Enrichment of Bifidobacteria From Human Gut Contents by Oligofructose Using Continuous Culture." FEMS Microbiol Lett 118, 121-127, 1994.
9. Wang, X, and Gibson, GR: "Effects of the In Vitro Fermentation of Oligofructose and Inulin by Bacteria Growing in the Human Large Intestine." J Appl Bacteriol 75, 373-380, 1993.
10. De Vries, W, and Stouthamer, AH: "Carbohydrate Metabolism in Bifidobacterium bifidum var Pennsylvanicus." Biochim Biophys Acta 136, 415-425, 1967.
11. Scardovi, V: "The Fructose-6-Phosphate Shunt as a Peculiar Pattern of Hexose Degradation in the Genus Bifidobacterium." Ann Microbiol Enzymol 15, 19-24, 1965.
12. Gibson, GR, Beatty, ER, Wang, X, and Cummings, JH: "Selective Stimulation of Bifidobacteria in the Human Colon by Oligofructose and Inulin." Gastroenterology 108, 975-982, 1995.
13. Metchnikoff, E: The Prolongation of Life. New York: Putman, 1908, pp 1-38.
14. Hoover, DG, and Hughes, DB: "Current Status and Future Trends of Bifidobacteria-Related Research and Products in the USA." Bifidobacteria Microflora 10, 113-121, 1991.
15. Mitsuoka, T: "Bifidobacteria and Their Role in Human Health". J Ind Microbiol 6, 263-267, 1990.
16. Nair, PP: "Role of Bile Acids and Neutral Sterols in Carcinogenesis." Am J Clin Nutr 48, 768-774, 1988.
17. 1 Mice." Nutr Cancer 16, 249-257, 1991.
18. Hosono, A, Wardojo, R, and Otani, H: "Inhibitory Effects of Lactic Acid Bacteria From Fermented Milk on the Mutagenicities of Volatile Nitrosamines." Agric Biol Chem 54, 16-39, 1990.
19. Marteau, P, Pochart, P, Flourié, B, Pellier, P, Santos, L, et al.: "Effect of Chronic Ingestion of a Fermented Dairy Product Containing Lactobacillus acidophilus and Bifidobacterium bifidum on Metabolic Activities of the Colonic Flora in Humans." Am J Clin Nutr 52, 685-688, 1990.
20. Peters, RK, Pike, MC, Garabrant, D, and Mack, TM: "Diet and Colon Cancer in Los Angeles County, California." Cancer Causes Control 3, 457-473, 1992.
21. Young, TB, and Wolf, DA: "Case-Control Study of Proximal and Distal Colon Cancer and Diet in Wisconsin." Int J Cancer 42, 167-175, 1988.
22. Kampman, E, Goldbohm, RA, Van den Brandt, PA, and Van't Veer, P: "Fermented Dairy Products, Calcium, and Colorectal Cancer in the Netherlands Cohort Study." Cancer Res 54, 3186-3190, 1992.
23. Beerens, H: "An Elective and Selective Medium for Bifidobacterium spp." Lett Appl Microbiol 11, 155-157, 1990.
24. Goldin, BR, and Gorbach, SL: "The Relationship Between Diet and Rat Fecal Bacterial Enzymes Implicated in Colon Cancer." JNCI 25, 371-375, 1976.
25. Yuen, CT, Price, RG, Richardson, AC, and Praili, PFG: "Colorimetric Assays for N-Acetyl-β-D-Glucosammidase and β-D-Galactosidase in Human Urine Using Newly Developed φ-Nitrosteryl Substrates." Clin Chim Acta 124, 195-204, 1982.
26. Grundy, SM, Ahrens, EH, and Miettinen, TA: "Quantitative Isolation and Gas-Liquid Chromatographic Analysis of Total Fecal Bile Acids." J Lipid Res 6, 397-410, 1965.
27. Stempfel, RS, and Sidbury, JB: "Studies With Hydroxysteroid Dehydrogenase: Simplified Method for Enzymatic Estimation of 3- and 17-Hydroxysteroids. J Clin Endocrinol 24, 367-372, 1964.
28. Mallet, AK, and Rowland, IR: "Factors Affecting the Gut Microflora." In Role of the Gut Flora in Toxicity and Cancer, IR Rowland (ed). London: Academic, 1988, pp 347-383.
29. Bouhnik, Y, Pochart, P, Marteau, P, Arlet, G, Goderel, I, et al.: "Fecal Recovery in Humans of Viable Bifidobacterium sp Ingested in Fermented Milk." Gastroenterology 102, 875-878, 1992.
30. Florent, C, Flourié, B, Leblond, A, Rautureau, M, Bernier, JJ, et al.: "Influence of Chronic Lactulose Ingestion on the Colonic Metabolism of Lactulose in Man (An In Vivo Study)." J Clin Invest 75, 608-613, 1985.
31. Goldin, BR, and Gorbach, SL: "The Effect of Milk and Lactobacillus Feeding on Human Intestinal Bacterial Enzyme Activity." Am J Clin Nutr 39, 756-761, 1984.
32. Van Munster, IP, Tangerman, A, and Nagengast, FM: "Effect of Resistant Starch on Colonic Fermentation, Bile Acid Metabolism, and Mucosal Proliferation." Dig Dis Sci 39, 834-842, 1994.
33. Rowland, IR, and Tanaka, R: "The Effects of Transgalactosylated Oligosaccharides on Gut Flora Metabolism in Rats Associated With a Human Faecal Microflora." J Appl Bacteriol 14, 667-674, 1993.
34. Goldin, BR, Swenson, L, Dwyer, J, Sexton, M, and Gorbach, SL: "Effect of Diet and Lactobacillus acidophilus Supplements on Human Fecal Bacterial Enzymes." JNCI 64, 255-267, 1980.
35. Fuller, R: "Problems and Prospects." In Probiotics. The Scientific Basis, R. Fuller (ed). London: Chapman & Hall, 1992, pp 377-386.
36. Sacquet, E, Leprince, C, and Riottot, M: "Effect of Different Modifications of a Semi-Synthetic Diet on Bile Acid Metabolism in Axenic an Holoxenic Rats." Ann Biol Anim Biochem Biophys 19, 1677-1688, 1979.
37. Van Berge Henegouven, GP, Van Der Werf, SDJ, and Ruben, ATH: "Effect of Long-Term Lactulose Ingestion on Secondary Bile Salt Metabolism in Man: Potential Protective Effect of Lactulose in Colonic Carcinogenesis." Gut 28, 675-680, 1987.
38. Riottot, M, Olivier, P, Huet, A, Caboche, JJ, Parquet, M, et al.: "Hypolipidemic Effects of β-Cyclodextrin in the Hamster and in the Genetically Hypercholesterolemic Rico Rat." Lipids 28, 181-188, 1993.