Involvement of lipogenesis in the lower VLDL secretion induced by oligofructose in rats

British Journal of Nutrition

Volumn 76, Issue 6, 1996, Pages 881-890

  Kok, B Y N ^a   Roberfroid, M ^a   Robert, A ^a   Delzenne, N ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Fructans; Lipogenesis; Liver; Very low density lipoproteins

Indexed keywords

FATTY ACID SYNTHASE; FRUCTOSE; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; GLYCEROPHOSPHATE; OLIGOMER; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME ACTIVITY; FATTY ACID SYNTHESIS; LIPID LIVER LEVEL; LIPOGENESIS; LIPOPROTEIN BLOOD LEVEL; LIVER CELL; MALE; NONHUMAN; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; FATTY ACIDS; FRUCTOSE; GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE; LIPIDS; LIPOPROTEINS, VLDL; LIVER; MALE; OLIGOSACCHARIDES; PHOSPHOLIPIDS; RATS; RATS, WISTAR; TRIGLYCERIDES;

ANIMALIA; RATTUS NORVEGICUS;

EID: 0030465359     PISSN: 00071145     EISSN: None     Source Type: Journal    
DOI: 10.1079/BJN19960094     Document Type: Article

References (16)

1. Arbeeny, C. M., Meyers, D. S., Bergquist, K. E. & Gregg, R. E. (1992). Inhibition of fatty acid synthesis decreases very-low-density lipoprotein secretion in the hamster. Journal of Lipid Research 33, 843-851.
2. Bates, E. J. & Saggerson, D. (1977). A selective decrease in mitochondrial glycerol phosphate acyltransferase activity in livers from streptozotocin-diabetic rats. FEES Letters 64, 36-39.
3. Beynen, A., Vaartjes, W. & Geelen, M. (1979). Opposite effects of insulin and glucagon in acute hormonal control of hepatic lipogenesis. Diabetes 28, 828-835.
4. Beynen, A., Vaartjes, W. & Geelen, M. (1980). Acute effects of insulin on fatty acid metabolism in isolated hepatocytes. Hormone and Metabolic Research 12, 425-430.
5. Björnsson, O. J., Duerden, J. M., Bartlett, S. M., Sparks, J. D., Sparks, C. E. & Gibbons, G. F. (1992). The role of pancreatic hormones in the regulation of lipid storage, oxidation and secretion in primary cultures of rat hepatocytes. Biochemical Journal 281, 381-386.
6. Boll, M., Weber, L. W., Stampfl, A. & Messner, B. (1994). Lipogenic enzymes of rat liver and adipose tissue. Dietary variations and effect of polychlorinated biphenyls. Zeitschrift für Naturforschung 49C, 665-678.
7. Braun, J. & Severson, D. L. (1992). Regulation of the synthesis, processing and translocation of lipoprotein lipase. Biochemical Journal 287, 337-347.
8. Cheng, C. & Saggerson, E. (1978). Rapid antagonistic actions of noradrenaline and insulin on rat adipocyte phosphatidate phosphohydrolase activity. FEES Letters 93, 120-124.
9. Clarke, S. D. & Jump, D. B. (1994). Dietary polyunsaturated fatty acid regulation of gene transcription. Annual Review of Nutrition 14, 83-98.
10. Deboyser, D., Goethals, F., Krack, G. & Roberfroid, M. (1989). Investigation into the mechanism of tetracycline-induced steatosis: study in isolated hepatocytes. Toxicological and Applied Pharmacology 97, 473-479.
11. Declercq, P., Debeer, L. & Mannaerts, G. (1982). Role of glycerol-3-phosphate and glycerophosphate acyltransferase in the nutritional control of hepatic triacylglycerol synthesis. Biochemical Journal 204, 247-256.
12. de Deckere, E. A., Kloots, W. & van Amelsvoort, J. M. (1995). Both raw and retrograded starch decrease serum triacylglycerol concentration and fat accretion in the rat. British Journal of Nutrition 73, 287-298.
13. Delzenne, N., Kok, N., Fiordaliso, M., Deboyser, D., Goethals, F. & Roberfroid, M. (1993). Dietary fructooligosaccharides modify lipid metabolism in rats. American Journal of Clinical Nutrition 57, 8208.
14. Delzenne, N. & Roberfroid, M. (1994). Physiological effects of non digestible oligosaccharides. Food and Science Technology 27, 1-6.
15. Wang, X. & Gibson, G. (1993). Effects of the in vitro fermentation of oligofructose and inulin by bacteria growing in the human large intestine. Journal of Applied Bacteriology 75, 373-380.
16. Wright, R. S., Anderson, J. W. & Briges, S. R. (1990). Propionate inhibits hepatocyte lipids synthesis. Proceedings of the Society for Experimental Biology and Medicine 195, 26-29.