-
2
-
-
0032103277
-
Atorvastatin and gemfibrozil metabolites, but not the parent drugs, are potent antioxidants against lipoprotein oxidation
-
Aviram M., Rosenblat M., Bisgaier C.L., and Newton R.S. Atorvastatin and gemfibrozil metabolites, but not the parent drugs, are potent antioxidants against lipoprotein oxidation. Atherosclerosis 138 (1998) 271-280
-
(1998)
Atherosclerosis
, vol.138
, pp. 271-280
-
-
Aviram, M.1
Rosenblat, M.2
Bisgaier, C.L.3
Newton, R.S.4
-
3
-
-
0031690802
-
Biochemical and clinical consequences of CoQ10 biosynthesis by lipid-lowering HMG-CoA reductase inhibitors (statins): A critical review
-
Bliznakov E.G., and Wilkins D.J. Biochemical and clinical consequences of CoQ10 biosynthesis by lipid-lowering HMG-CoA reductase inhibitors (statins): A critical review. Adv. Therap. 15 (1998) 218-228
-
(1998)
Adv. Therap.
, vol.15
, pp. 218-228
-
-
Bliznakov, E.G.1
Wilkins, D.J.2
-
5
-
-
0031455734
-
Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinson's disease
-
Cassarino D.S., Fall C.P., Swerdlow R.H., Smith T.S., Halvorsen E.M., Miller S.W., Parks J.P., Parker Jr. W.D., and Bennett Jr. J.P. Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinson's disease. Biochim. Biophys. Acta 1362 (1997) 77-86
-
(1997)
Biochim. Biophys. Acta
, vol.1362
, pp. 77-86
-
-
Cassarino, D.S.1
Fall, C.P.2
Swerdlow, R.H.3
Smith, T.S.4
Halvorsen, E.M.5
Miller, S.W.6
Parks, J.P.7
Parker Jr., W.D.8
Bennett Jr., J.P.9
-
6
-
-
0031708168
-
Neostriatal mechanisms in Parkinson's disease
-
Chase T.N., Oh J.D., and Blanchet P.J. Neostriatal mechanisms in Parkinson's disease. Neurology 51 (1998) S30-S35
-
(1998)
Neurology
, vol.51
-
-
Chase, T.N.1
Oh, J.D.2
Blanchet, P.J.3
-
7
-
-
0031736655
-
Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors in transplant patients: are the statins mechanistically similar?
-
Christians U., Jacobsen W., and Floren L.C. Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors in transplant patients: are the statins mechanistically similar?. Pharmacol. Therapeut. 80 (1998) 1-34
-
(1998)
Pharmacol. Therapeut.
, vol.80
, pp. 1-34
-
-
Christians, U.1
Jacobsen, W.2
Floren, L.C.3
-
8
-
-
8544283254
-
The Comet Assay for DNA damage and repair: principles, applications, and limitations
-
Collins A.R. The Comet Assay for DNA damage and repair: principles, applications, and limitations. Mol. Biotechnol. 26 (2004) 249-261
-
(2004)
Mol. Biotechnol.
, vol.26
, pp. 249-261
-
-
Collins, A.R.1
-
9
-
-
32044466239
-
Does measurement of oxidative damage to DNA have clinical significance?
-
Cooke M.S., Olinski R., and Evans M.D. Does measurement of oxidative damage to DNA have clinical significance?. Clin. Chim. Acta 365 (2006) 30-49
-
(2006)
Clin. Chim. Acta
, vol.365
, pp. 30-49
-
-
Cooke, M.S.1
Olinski, R.2
Evans, M.D.3
-
10
-
-
0027686249
-
Oxidative stress, glutamate, and neurodegenerative disorders
-
Coyle J.T., and Puttfarcken P. Oxidative stress, glutamate, and neurodegenerative disorders. Science 262 (1993) 689-695
-
(1993)
Science
, vol.262
, pp. 689-695
-
-
Coyle, J.T.1
Puttfarcken, P.2
-
11
-
-
0035875462
-
Use of statins in CNS disorders
-
Cucchiara B., and Kasner S.E. Use of statins in CNS disorders. J. Neurol. Sci. 187 (2001) 81-89
-
(2001)
J. Neurol. Sci.
, vol.187
, pp. 81-89
-
-
Cucchiara, B.1
Kasner, S.E.2
-
12
-
-
33845680365
-
Lovastatin protects human endothelial cells from the genotoxic and cytotoxic effects of the anticancer drugs doxorubicin and etoposide
-
Damrot J., Nübel T., Epe B., Roos W.P., Kaina B., and Fritz G. Lovastatin protects human endothelial cells from the genotoxic and cytotoxic effects of the anticancer drugs doxorubicin and etoposide. Brit. J. Pharmacol. 149 (2006) 988-997
-
(2006)
Brit. J. Pharmacol.
, vol.149
, pp. 988-997
-
-
Damrot, J.1
Nübel, T.2
Epe, B.3
Roos, W.P.4
Kaina, B.5
Fritz, G.6
-
13
-
-
42649144101
-
Oxidative and nitrative protein modifications in Parkinson's disease
-
Danielson S.R., and Andersen J.K. Oxidative and nitrative protein modifications in Parkinson's disease. Free Radical Bio. Med. 44 (2008) 1787-1794
-
(2008)
Free Radical Bio. Med.
, vol.44
, pp. 1787-1794
-
-
Danielson, S.R.1
Andersen, J.K.2
-
14
-
-
43049175139
-
Role of reactive oxygen species in the neurotoxicity of environmental agents implicated in Parkinson's disease
-
Drechsel D.A., and Patel M. Role of reactive oxygen species in the neurotoxicity of environmental agents implicated in Parkinson's disease. Free Radical Bio. Med. 44 (2008) 1873-1886
-
(2008)
Free Radical Bio. Med.
, vol.44
, pp. 1873-1886
-
-
Drechsel, D.A.1
Patel, M.2
-
15
-
-
0000351673
-
Hypoxic-ischemic brain injury and oxidative stress
-
Siegel G.J. (Ed), Lippincott-Raven, Philadelphia
-
Dugan L.L., and Choi D.W. Hypoxic-ischemic brain injury and oxidative stress. In: Siegel G.J. (Ed). Basic neurochemistry: molecular, cellular and medical aspects. sixth ed. (1999), Lippincott-Raven, Philadelphia 711-729
-
(1999)
Basic neurochemistry: molecular, cellular and medical aspects. sixth ed.
, pp. 711-729
-
-
Dugan, L.L.1
Choi, D.W.2
-
16
-
-
0344628593
-
An HPLC method for the determination of atorvastatin and its impurities in bulk drug and tablets
-
Ertürk S., Aktaş E.S., Ersoy L., and Fiçicioǧlu S. An HPLC method for the determination of atorvastatin and its impurities in bulk drug and tablets. J. Pharmaceut. Biomed. 33 (2003) 1017-1023
-
(2003)
J. Pharmaceut. Biomed.
, vol.33
, pp. 1017-1023
-
-
Ertürk, S.1
Aktaş, E.S.2
Ersoy, L.3
Fiçicioǧlu, S.4
-
17
-
-
0033104442
-
+-induced apoptosis in human SH-SY5Y neuroblastoma cells
-
+-induced apoptosis in human SH-SY5Y neuroblastoma cells. J. Neurosci Res. 55 5 (1999) 620-628
-
(1999)
J. Neurosci Res.
, vol.55
, Issue.5
, pp. 620-628
-
-
Fall, C.P.1
Bennett Jr., J.P.2
-
18
-
-
0041883143
-
A comparative study of the in vitro antioxidant activity of statins
-
Franzoni F., Quiñones-Galvan A., Regoli F., Ferranninia E., and Galettaa F. A comparative study of the in vitro antioxidant activity of statins. Int. J. Cardiol. 90 (2003) 317-321
-
(2003)
Int. J. Cardiol.
, vol.90
, pp. 317-321
-
-
Franzoni, F.1
Quiñones-Galvan, A.2
Regoli, F.3
Ferranninia, E.4
Galettaa, F.5
-
19
-
-
0018095085
-
Oxidative pathway for catecholamines in the genesis of neuromelanin and cytotoxic quinones
-
Graham D.G. Oxidative pathway for catecholamines in the genesis of neuromelanin and cytotoxic quinones. Mol. Pharmacol. 14 (1978) 633-643
-
(1978)
Mol. Pharmacol.
, vol.14
, pp. 633-643
-
-
Graham, D.G.1
-
20
-
-
0018148688
-
Autoxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine, and related compounds toward C1300 neuroblastoma cells in vitro
-
Graham D.G., Tiffany S.M., Bell W.R., and Gutknecht W.F. Autoxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine, and related compounds toward C1300 neuroblastoma cells in vitro. Mol. Pharmacol. 14 (1978) 644-653
-
(1978)
Mol. Pharmacol.
, vol.14
, pp. 644-653
-
-
Graham, D.G.1
Tiffany, S.M.2
Bell, W.R.3
Gutknecht, W.F.4
-
21
-
-
0031881755
-
Hydrophilicity/lipophilicity: relevance for the pharmacology and clinical effects of HMG-CoA reductase inhibitors
-
Hamelin B.A., and Turgeon J. Hydrophilicity/lipophilicity: relevance for the pharmacology and clinical effects of HMG-CoA reductase inhibitors. Trends Pharmacol. Sci. 19 (1998) 26-37
-
(1998)
Trends Pharmacol. Sci.
, vol.19
, pp. 26-37
-
-
Hamelin, B.A.1
Turgeon, J.2
-
22
-
-
0029460699
-
Differential regulation by cytokines of human astrocyte nitric oxide production
-
Hu S., Sheng W.S., Peterson P.K., and Chao C.C. Differential regulation by cytokines of human astrocyte nitric oxide production. Glia 15 (1995) 491-494
-
(1995)
Glia
, vol.15
, pp. 491-494
-
-
Hu, S.1
Sheng, W.S.2
Peterson, P.K.3
Chao, C.C.4
-
23
-
-
0030838365
-
The effect of Simvastatin on the plasma antioxidant concentrations in patients with hypercholesterolaemia
-
Human J.A., Ubbink J.B., Jerling J.J., Delport R., Vermaak W.J., Vorster H.H., Lagendijk J., and Potgieter H.C. The effect of Simvastatin on the plasma antioxidant concentrations in patients with hypercholesterolaemia. Clin. Chim. Acta 263 (1997) 67-77
-
(1997)
Clin. Chim. Acta
, vol.263
, pp. 67-77
-
-
Human, J.A.1
Ubbink, J.B.2
Jerling, J.J.3
Delport, R.4
Vermaak, W.J.5
Vorster, H.H.6
Lagendijk, J.7
Potgieter, H.C.8
-
24
-
-
0345600914
-
2A antagonists as novel non-dopaminergic therapy for motor dysfunction in Parkinson's disease
-
2A antagonists as novel non-dopaminergic therapy for motor dysfunction in Parkinson's disease. Neurology 61 (2003) S32-S38
-
(2003)
Neurology
, vol.61
-
-
Jenner, P.1
-
25
-
-
0029432331
-
The role of transition metals in the pathogenesis of Parkinson's disease
-
Kienzl E., Linert W., Jelllinger K., Puchinger L., Stachelberger H., and Jameson R.F. The role of transition metals in the pathogenesis of Parkinson's disease. J. Neurol. Sci. 134 (1995) 69-78
-
(1995)
J. Neurol. Sci.
, vol.134
, pp. 69-78
-
-
Kienzl, E.1
Linert, W.2
Jelllinger, K.3
Puchinger, L.4
Stachelberger, H.5
Jameson, R.F.6
-
26
-
-
0025200735
-
Predicting Parkinson's disease
-
Langston J.W. Predicting Parkinson's disease. Neurology 40 (1990) 70-74
-
(1990)
Neurology
, vol.40
, pp. 70-74
-
-
Langston, J.W.1
-
27
-
-
3042640736
-
High doses of simvastatin, pravastatin, and cholesterol reduce brain cholesterol synthesis in guinea pigs
-
Lütjohann D., Stroick M., Bertsch T., Kühl S., Lindenthal B., Thelen K., Andersson U., Björkhem I., Von Bergmann K., and Fassbender K. High doses of simvastatin, pravastatin, and cholesterol reduce brain cholesterol synthesis in guinea pigs. Steroids 69 (2004) 431-438
-
(2004)
Steroids
, vol.69
, pp. 431-438
-
-
Lütjohann, D.1
Stroick, M.2
Bertsch, T.3
Kühl, S.4
Lindenthal, B.5
Thelen, K.6
Andersson, U.7
Björkhem, I.8
Von Bergmann, K.9
Fassbender, K.10
-
28
-
-
0034011261
-
Oxyradicals and DNA damage
-
Marnett L.J. Oxyradicals and DNA damage. Carcinogenesis 21 (2000) 361-370
-
(2000)
Carcinogenesis
, vol.21
, pp. 361-370
-
-
Marnett, L.J.1
-
30
-
-
0031438501
-
Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages
-
Pahan K., Sheikh F.G., Namboodiri A.M., and Singh I. Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages. J. Clin. Invest. 100 (1997) 2671-2679
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 2671-2679
-
-
Pahan, K.1
Sheikh, F.G.2
Namboodiri, A.M.3
Singh, I.4
-
31
-
-
0032588330
-
Parkinson's disease: a multifactorial neurodegenerative disorder
-
Riess O., and Kruger R. Parkinson's disease: a multifactorial neurodegenerative disorder. J. Neural Transm. 56 (1999) 113-125
-
(1999)
J. Neural Transm.
, vol.56
, pp. 113-125
-
-
Riess, O.1
Kruger, R.2
-
32
-
-
0031866530
-
Cellular mechanisms of resistance to chronic oxidative stress
-
Sagara Y., Dargusch R., Chambers D., Davis J., Schubert D., and Maher P. Cellular mechanisms of resistance to chronic oxidative stress. Free Radical Bio. Med. 24 (1997) 1375-1389
-
(1997)
Free Radical Bio. Med.
, vol.24
, pp. 1375-1389
-
-
Sagara, Y.1
Dargusch, R.2
Chambers, D.3
Davis, J.4
Schubert, D.5
Maher, P.6
-
33
-
-
0035214256
-
Neurochemical findings in the MPTP model of Parkinson's disease
-
Schmidt N., and Ferger B. Neurochemical findings in the MPTP model of Parkinson's disease. J. Neural Transm. 108 (2001) 1263-1282
-
(2001)
J. Neural Transm.
, vol.108
, pp. 1263-1282
-
-
Schmidt, N.1
Ferger, B.2
-
34
-
-
24044466782
-
A beneficial effect of simvastatin on DNA damage in 242T allele of NADPH oxidase p22phox in hypercholesterolemic patients
-
Shin M.-J., Cho E.-Y., Jang Y., Lee J.H., Shim W.-H., Cho S.-Y., Rim S.-J., Kang S.-K., Ha J.-W., Ko Y.-H., Kim S.-S., Park H.Y., and Chung N. A beneficial effect of simvastatin on DNA damage in 242T allele of NADPH oxidase p22phox in hypercholesterolemic patients. Clin. Chim. Acta 360 (2005) 46-51
-
(2005)
Clin. Chim. Acta
, vol.360
, pp. 46-51
-
-
Shin, M.-J.1
Cho, E.-Y.2
Jang, Y.3
Lee, J.H.4
Shim, W.-H.5
Cho, S.-Y.6
Rim, S.-J.7
Kang, S.-K.8
Ha, J.-W.9
Ko, Y.-H.10
Kim, S.-S.11
Park, H.Y.12
Chung, N.13
-
35
-
-
0028075410
-
Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
-
Sian J., Dexter D.T., Lees A.J., Daniel S., Agid Y., Javoy-Agid F., Jenner P., and Marsden C.D. Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann. Neurol. 36 (1994) 348-355
-
(1994)
Ann. Neurol.
, vol.36
, pp. 348-355
-
-
Sian, J.1
Dexter, D.T.2
Lees, A.J.3
Daniel, S.4
Agid, Y.5
Javoy-Agid, F.6
Jenner, P.7
Marsden, C.D.8
-
36
-
-
0034693836
-
Microgels for estimation of DNA strand breaks, DNA protein crosslinks and apoptosis
-
Singh N.P. Microgels for estimation of DNA strand breaks, DNA protein crosslinks and apoptosis. Mutat. Res-Fund. Mol. M. 455 (2000) 111-127
-
(2000)
Mutat. Res-Fund. Mol. M.
, vol.455
, pp. 111-127
-
-
Singh, N.P.1
-
37
-
-
0036716889
-
MPTP: insights into neurodegeneration
-
Speciale G.S. MPTP: insights into neurodegeneration. Neurotoxicol. Teratol. 24 (2002) 607-620
-
(2002)
Neurotoxicol. Teratol.
, vol.24
, pp. 607-620
-
-
Speciale, G.S.1
-
38
-
-
0032826065
-
Neuroprotective properties of statins in cerebral ischemia and stroke
-
Vaughan C.J., and Delanty N. Neuroprotective properties of statins in cerebral ischemia and stroke. Stroke 30 (1999) 1969-1973
-
(1999)
Stroke
, vol.30
, pp. 1969-1973
-
-
Vaughan, C.J.1
Delanty, N.2
-
39
-
-
10244235267
-
Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease
-
Vodovotz Y., Lucia M.S., Flanders K.C., Chesler L., Xie Q.W., Smith T.W., Weidner J., Mumford R., Webber R., Nathan C., Roberts A.B., Lippa C.F., and Sporn M.B. Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease. J. Exp. Med. 184 (1996) 1425-1433
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1425-1433
-
-
Vodovotz, Y.1
Lucia, M.S.2
Flanders, K.C.3
Chesler, L.4
Xie, Q.W.5
Smith, T.W.6
Weidner, J.7
Mumford, R.8
Webber, R.9
Nathan, C.10
Roberts, A.B.11
Lippa, C.F.12
Sporn, M.B.13
-
40
-
-
3242695252
-
Genes, proteins, and neurotoxins involved in Parkinson's disease
-
Von Bohlen und Halbach O., Schober A., and Krieglstein K. Genes, proteins, and neurotoxins involved in Parkinson's disease. Prog. Neurobiol. 73 (2004) 151-177
-
(2004)
Prog. Neurobiol.
, vol.73
, pp. 151-177
-
-
Von Bohlen und Halbach, O.1
Schober, A.2
Krieglstein, K.3
-
41
-
-
0033772113
-
Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors
-
Wolozin B., Kellman W., Rousseau P., Celesia G.G., and Siegel G. Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors. Arch. Neurol-Chicago 57 (2000) 1439-1443
-
(2000)
Arch. Neurol-Chicago
, vol.57
, pp. 1439-1443
-
-
Wolozin, B.1
Kellman, W.2
Rousseau, P.3
Celesia, G.G.4
Siegel, G.5
-
42
-
-
0027283898
-
Free radicals and their scavengers in Parkinson's disease
-
Yoshikawa T. Free radicals and their scavengers in Parkinson's disease. Eur. Neurol. 33 (1993) 60-68
-
(1993)
Eur. Neurol.
, vol.33
, pp. 60-68
-
-
Yoshikawa, T.1
|