A beneficial effect of simvastatin on DNA damage in 242T allele of the NADPH oxidase p22phox in hypercholesterolemic patients

Clinica Chimica Acta

Volumn 360, Issue 1-2, 2005, Pages 46-51

  Shin, Min Jeong ^a   Eun, Young Cho ^a   Jang, Yangsoo ^a   Jong, Ho Lee ^a   Shim, Won Heum ^a   Cho, Seung Yun ^a   Rim, Se Joong ^a   Kang, Seok Min ^a   Ha, Jong Won ^a   Ko, Young Guk ^a   Kim, Sung Soon ^a   Hyun, Young Park ^a   Chung, Namsik ^a,b  

^a Yonsei University College of Medicine   (South Korea)

^b Yonsei University   (South Korea)

Author keywords

DNA damage; NADPH oxidase; Polymorphism; Simvastatin

Indexed keywords

GENOMIC DNA; PROTEIN P22; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SIMVASTATIN;

ADULT; AGED; ANTIOXIDANT ACTIVITY; ARTICLE; CLINICAL EXAMINATION; CLINICAL TRIAL; COMET ASSAY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFECT; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENOTYPE; HOMOZYGOTE; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; LYMPHOCYTE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; QUANTITATIVE ASSAY;

AGED; ALLELES; ANTICHOLESTEREMIC AGENTS; COMET ASSAY; DNA DAMAGE; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; HYPERCHOLESTEROLEMIA; LYMPHOCYTES; MALE; MEMBRANE TRANSPORT PROTEINS; MIDDLE AGED; NADPH OXIDASE; OXIDATION-REDUCTION; PHOSPHOPROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; SIMVASTATIN;

EID: 24044466782     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cccn.2005.04.001     Document Type: Article

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