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Volumn 181, Issue 1, 2003, Pages 25-38

Dependence on electron transport chain function and intracellular signaling of genomic responses in SH-SY5Y cells to the mitochondrial neurotoxin MPP+

Author keywords

Apoptosis; Methylpyridinium; Microarray; Mitochondria; Neuroblastoma; Parkinsonism

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; COMPLEMENTARY DNA; METHYLPYRIDINIUM ION; NEUROTOXIN; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN C JUN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UNCLASSIFIED DRUG; UO 126;

EID: 0037403845     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4886(02)00045-6     Document Type: Article
Times cited : (17)

References (47)
  • 1
    • 0037083131 scopus 로고    scopus 로고
    • Inhibition by R(+) or S(-) pramipexole of caspase activation and cell death induced by methylpyridinium ion or beta amyloid peptide in SH-SY5Y neuroblastoma
    • Abramova N.A., Cassarino D.S., Khan S.M., Painter T.W., Bennett J.P. Jr. Inhibition by R(+) or S(-) pramipexole of caspase activation and cell death induced by methylpyridinium ion or beta amyloid peptide in SH-SY5Y neuroblastoma. J. Neurosci. Res. 67:2002;494-500.
    • (2002) J. Neurosci. Res. , vol.67 , pp. 494-500
    • Abramova, N.A.1    Cassarino, D.S.2    Khan, S.M.3    Painter, T.W.4    Bennett J.P., Jr.5
  • 2
    • 0021829406 scopus 로고
    • Permanent human parkinsonism due to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): Seven cases
    • Ballard P.A., Tetrud J.W., Langston J.W. Permanent human parkinsonism due to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) seven cases. Neurology. 35:1985;949-956.
    • (1985) Neurology , vol.35 , pp. 949-956
    • Ballard, P.A.1    Tetrud, J.W.2    Langston, J.W.3
  • 3
    • 23444443039 scopus 로고
    • CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest
    • Barone M.V., Crozat A., Tabaee A., Philipson L., Ron D. CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest. Genes Dev. 8:1994;453-464.
    • (1994) Genes Dev. , vol.8 , pp. 453-464
    • Barone, M.V.1    Crozat, A.2    Tabaee, A.3    Philipson, L.4    Ron, D.5
  • 6
    • 0001496694 scopus 로고
    • A primate model of parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Burns R.S., Chiueh C.C., Markey S.P., Ebert M.H., Jacobowitz D.M., Kopin I.J. A primate model of parkinsonism selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc. Natl. Acad. Sci. USA. 80:1983;4546-4550.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 4546-4550
    • Burns, R.S.1    Chiueh, C.C.2    Markey, S.P.3    Ebert, M.H.4    Jacobowitz, D.M.5    Kopin, I.J.6
  • 7
    • 0032904412 scopus 로고    scopus 로고
    • An evaluation of the role of mitochondria in neurodegenerative diseases: Mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration
    • Cassarino D.S., Bennett J.P. Jr. An evaluation of the role of mitochondria in neurodegenerative diseases mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration. Brain Res. 1:1999;1-25.
    • (1999) Brain Res. , vol.1 , pp. 1-25
    • Cassarino, D.S.1    Bennett J.P., Jr.2
  • 10
    • 0021276089 scopus 로고
    • Metabolism of the neurotoxic tertiary amine. MPTP, by brain monoamine oxidase
    • Chiba K., Trevor A., Castagnoli N. Metabolism of the neurotoxic tertiary amine. MPTP, by brain monoamine oxidase. Biochem. Biophys. Res. Commun. 120:1984;547-578.
    • (1984) Biochem. Biophys. Res. Commun. , vol.120 , pp. 547-578
    • Chiba, K.1    Trevor, A.2    Castagnoli, N.3
  • 13
    • 0034006478 scopus 로고    scopus 로고
    • Deficiency of inducible nitric oxide synthase protects against MPTP toxicity in vivo
    • Dehmer T., Lindenau J., Haid S., Dichgans J., Schulz J.B. Deficiency of inducible nitric oxide synthase protects against MPTP toxicity in vivo. J. Neurochem. 74:2000;2213-2216.
    • (2000) J. Neurochem. , vol.74 , pp. 2213-2216
    • Dehmer, T.1    Lindenau, J.2    Haid, S.3    Dichgans, J.4    Schulz, J.B.5
  • 14
    • 0345533444 scopus 로고    scopus 로고
    • Interaction among nitric oxide and Bcl-family proteins in a neural cell-based MPP+ model of Parkinson's disease I
    • In press
    • Dennis, J., Bennett, Jr., J.P., 2002. Interaction among nitric oxide and Bcl-family proteins in a neural cell-based MPP+ model of Parkinson's disease I. J. Neurosci Res. (In press).
    • (2002) J. Neurosci Res.
    • Dennis, J.1    Bennett J.P., Jr.2
  • 15
    • 0033104442 scopus 로고    scopus 로고
    • +-induced apoptosis in human SH-SY5Y neuroblastoma cells
    • +-induced apoptosis in human SH-SY5Y neuroblastoma cells. J. Neurosci. Res. 55:1999;620-628.
    • (1999) J. Neurosci. Res. , vol.55 , pp. 620-628
    • Fall, C.P.1    Bennett J.P., Jr.2
  • 17
    • 0029982183 scopus 로고    scopus 로고
    • Physical and functional association between GADD153 and CCAAT/enhancer-binding protein beta during cellular stress
    • Fawcett T.W., Eastman H.B., Martindale J.L., Holbrook N.J. Physical and functional association between GADD153 and CCAAT/enhancer-binding protein beta during cellular stress. J. Biol. Chem. 271:1996;14285-14289.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14285-14289
    • Fawcett, T.W.1    Eastman, H.B.2    Martindale, J.L.3    Holbrook, N.J.4
  • 19
    • 0036019165 scopus 로고    scopus 로고
    • Mechanisms of cell death in neurodegenerative diseases: Fashion, fiction, and facts
    • Graeber M.B., Moran L.B. Mechanisms of cell death in neurodegenerative diseases fashion, fiction, and facts. Brain Pathol. 12:2002;385-390.
    • (2002) Brain Pathol. , vol.12 , pp. 385-390
    • Graeber, M.B.1    Moran, L.B.2
  • 20
    • 0037064274 scopus 로고    scopus 로고
    • Methypyridinium (MPP+)- and nerve growth factor-induced changes in pro- and anti-apoptotic signaling pathways in SH-SY5Y neuroblastoma cells
    • Halvorsen E.M., Dennis J., Keeney P.M., Sturgill T.W., Tuttle J.B., Bennett J.P. Jr. Methypyridinium (MPP+)- and nerve growth factor-induced changes in pro- and anti-apoptotic signaling pathways in SH-SY5Y neuroblastoma cells. Brain Res. 952:2002;98-110.
    • (2002) Brain Res. , vol.952 , pp. 98-110
    • Halvorsen, E.M.1    Dennis, J.2    Keeney, P.M.3    Sturgill, T.W.4    Tuttle, J.B.5    Bennett J.P., Jr.6
  • 21
    • 0000340348 scopus 로고
    • Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: Uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity
    • Javitch J.A., D'Amato R.J., Strittmatter S.M., Snyder S.H. Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity. Proc. Natl. Acad. Sci. USA. 82:1985;2173-2177.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 2173-2177
    • Javitch, J.A.1    D'Amato, R.J.2    Strittmatter, S.M.3    Snyder, S.H.4
  • 23
    • 0020680904 scopus 로고
    • Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
    • Langston J.W., Ballard P., Tetrud J.W., Irwin I. Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science. 219:1983;979-980.
    • (1983) Science , vol.219 , pp. 979-980
    • Langston, J.W.1    Ballard, P.2    Tetrud, J.W.3    Irwin, I.4
  • 24
    • 0021155228 scopus 로고
    • MPTP-induced parkinsonism in human and non-human primates-clinical and experimental aspects
    • Langston J.W., Langston E.B., Irwin I. MPTP-induced parkinsonism in human and non-human primates-clinical and experimental aspects. Acta Neurol. Scand. Suppl. 100:1984;49-54.
    • (1984) Acta Neurol. Scand. Suppl. , vol.100 , pp. 49-54
    • Langston, J.W.1    Langston, E.B.2    Irwin, I.3
  • 25
    • 0035976524 scopus 로고    scopus 로고
    • Regulation of cell survival by secreted proneurotrophins
    • Lee R., Kermani P., Teng K.K., Hempstead B.L. Regulation of cell survival by secreted proneurotrophins. Science. 294:2001;1945-1948.
    • (2001) Science , vol.294 , pp. 1945-1948
    • Lee, R.1    Kermani, P.2    Teng, K.K.3    Hempstead, B.L.4
  • 26
    • 0026546246 scopus 로고
    • Activation of the gadd153 promoter by genotoxic agents: A rapid and specific response to DNA damage
    • Luethy J.D., Holbrook N.J. Activation of the gadd153 promoter by genotoxic agents a rapid and specific response to DNA damage. Cancer Res. 52:1992;5-10.
    • (1992) Cancer Res. , vol.52 , pp. 5-10
    • Luethy, J.D.1    Holbrook, N.J.2
  • 29
    • 0026718086 scopus 로고
    • Brain, skeletal muscle, and platelet homogenate mitochondrial functions in Parkinson's disease
    • Mann V.M., Cooper J.M., Kriige D., Daniel S.E., Schapira A.H.V., Marsden D. Brain, skeletal muscle, and platelet homogenate mitochondrial functions in Parkinson's disease. Brain. 115:1992;333-342.
    • (1992) Brain , vol.115 , pp. 333-342
    • Mann, V.M.1    Cooper, J.M.2    Kriige, D.3    Daniel, S.E.4    Schapira, A.H.V.5    Marsden, D.6
  • 30
    • 0030597160 scopus 로고    scopus 로고
    • Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cells
    • Matsumoto M., Minami M., Takeda K., Sakao Y., Akira S. Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cells. FEBS Lett. 395:1996;143-147.
    • (1996) FEBS Lett. , vol.395 , pp. 143-147
    • Matsumoto, M.1    Minami, M.2    Takeda, K.3    Sakao, Y.4    Akira, S.5
  • 33
    • 0030725756 scopus 로고    scopus 로고
    • Furin: A mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins
    • Nakayama K. Furin a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins. Biochem. J. 327:1997;625-635.
    • (1997) Biochem. J. , vol.327 , pp. 625-635
    • Nakayama, K.1
  • 34
    • 0000705279 scopus 로고
    • Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
    • Nicklas W.J., Vyas I., Heikkila R.E. Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. Life Sci. 8:1985;223-228.
    • (1985) Life Sci. , vol.8 , pp. 223-228
    • Nicklas, W.J.1    Vyas, I.2    Heikkila, R.E.3
  • 35
    • 0032510758 scopus 로고    scopus 로고
    • Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
    • Offen D., Beart P.M., Cheung N.S., Pascoe C.J., Hochman A., Gorodin S., Melamed E., Bernard R., Bernard O. Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. Proc. Natl. Acad. Sci. USA. 95:1998;5789-5794.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5789-5794
    • Offen, D.1    Beart, P.M.2    Cheung, N.S.3    Pascoe, C.J.4    Hochman, A.5    Gorodin, S.6    Melamed, E.7    Bernard, R.8    Bernard, O.9
  • 36
    • 0024848034 scopus 로고
    • Abnormalities of the electron transport chain in idiopathic Parkinson's disease
    • Parker W.D. Jr., Boyson S.I., Parks J.K. Abnormalities of the electron transport chain in idiopathic Parkinson's disease. Ann. Neurol. 26:1989;719-723.
    • (1989) Ann. Neurol. , vol.26 , pp. 719-723
    • Parker W.D., Jr.1    Boyson, S.I.2    Parks, J.K.3
  • 37
    • 0029984860 scopus 로고    scopus 로고
    • Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity
    • Przedborski S., Jackson-Lewis V., Yokoyama R., Shibata T., Dawson V.L., Dawson T.M. Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity. Proc. Natl. Acad. Sci. USA. 93:1996;4565-4571.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 4565-4571
    • Przedborski, S.1    Jackson-Lewis, V.2    Yokoyama, R.3    Shibata, T.4    Dawson, V.L.5    Dawson, T.M.6
  • 38
    • 0037071834 scopus 로고    scopus 로고
    • Activator protein-1 and CCAAT/enhancer-binding protein mediated GADD153 expression is involved in deoxycholic acid-induced apoptosis
    • Qiao D., Im E., Qi W., Martinez J.D. Activator protein-1 and CCAAT/enhancer-binding protein mediated GADD153 expression is involved in deoxycholic acid-induced apoptosis. Biochim. Biophys. Acta. 1583:2002;108-116.
    • (2002) Biochim. Biophys. Acta , vol.1583 , pp. 108-116
    • Qiao, D.1    Im, E.2    Qi, W.3    Martinez, J.D.4
  • 39
    • 0022633481 scopus 로고
    • MPTP: A neurotoxin relevant to the pathophysiology of Parkinson's disease. The 1985 George C. Cotzias lecture
    • Snyder S.H., D'Amato R.J. MPTP a neurotoxin relevant to the pathophysiology of Parkinson's disease. The 1985 George C. Cotzias lecture. Neurology. 36:1986;250-258.
    • (1986) Neurology , vol.36 , pp. 250-258
    • Snyder, S.H.1    D'Amato, R.J.2
  • 40
    • 0036777178 scopus 로고    scopus 로고
    • Acute mitochondrial and chronic toxicological effects of 1-methyl-4-phenylpyridinium in human neuroblastoma cells
    • Stephans S.E., Miller G.W., Levey A.I., Greenamyre J.T. Acute mitochondrial and chronic toxicological effects of 1-methyl-4-phenylpyridinium in human neuroblastoma cells. Neurotoxicology. 23:2002;569-580.
    • (2002) Neurotoxicology , vol.23 , pp. 569-580
    • Stephans, S.E.1    Miller, G.W.2    Levey, A.I.3    Greenamyre, J.T.4
  • 42
    • 0030249597 scopus 로고    scopus 로고
    • Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity
    • Trimmer P.A., Smith T.S., Jung A.B., Bennett J.P. Jr. Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity. Neurodegeneration. 5:1996;233-239.
    • (1996) Neurodegeneration , vol.5 , pp. 233-239
    • Trimmer, P.A.1    Smith, T.S.2    Jung, A.B.3    Bennett J.P., Jr.4
  • 43
    • 0034666630 scopus 로고    scopus 로고
    • Disrupted mitochondrial electron transport function increases expression of anti-apoptotic bcl-2 and bcl-X(L) proteins in SH-SY5Y neuroblastoma and in Parkinson disease cybrid cells through oxidative stress
    • Veech G.A., Dennis J., Keeney P.M., Fall C.P., Swerdlow R.H., Parker W.D. Jr., Bennett J.P. Jr. Disrupted mitochondrial electron transport function increases expression of anti-apoptotic bcl-2 and bcl-X(L) proteins in SH-SY5Y neuroblastoma and in Parkinson disease cybrid cells through oxidative stress. J. Neurosci. Res. 61:2000;693-700.
    • (2000) J. Neurosci. Res. , vol.61 , pp. 693-700
    • Veech, G.A.1    Dennis, J.2    Keeney, P.M.3    Fall, C.P.4    Swerdlow, R.H.5    Parker W.D., Jr.6    Bennett J.P., Jr.7
  • 45
    • 0028170210 scopus 로고
    • A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
    • Vlahos C.J., Matter W.F., Hui K.Y., Brown R.F. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J. Biol. Chem. 269:1994;5241-5248.
    • (1994) J. Biol. Chem. , vol.269 , pp. 5241-5248
    • Vlahos, C.J.1    Matter, W.F.2    Hui, K.Y.3    Brown, R.F.4


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