Differential gene expression of fatty acid binding proteins during porcine adipogenesis

Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology

Volumn 151, Issue 2, 2008, Pages 147-152

  Samulin, Johanna ^a   Berget, Ingunn ^a,b   Lien, Sigbjørn ^a   Sundvold, Hilde ^a  

^a NORWEGIAN UNIVERSITY OF LIFE SCIENCES   (Norway)

^b NOFIMA   (Norway)

Author keywords

Adipogenesis; Differentiation; Fatty acid binding proteins; Gene expression; Peroxisome proliferator activated receptors; Pig; Proliferation; Stromal vascular cells

Indexed keywords

FATTY ACID BINDING PROTEIN; FATTY ACID BINDING PROTEIN 1; FATTY ACID BINDING PROTEIN 3; FATTY ACID BINDING PROTEIN 4; FATTY ACID BINDING PROTEIN 5; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; UNCLASSIFIED DRUG;

ADIPOGENESIS; ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CORRELATION ANALYSIS; FATTY ACID TRANSPORT; GENE EXPRESSION; METABOLIC REGULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SWINE;

SUIDAE; SUS; SUS SCROFA;

EID: 50049101713     PISSN: 10964959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbpb.2008.06.010     Document Type: Article

References (55)

1. Adida A., and Spener F. Adipocyte-type fatty acid-binding protein as inter-compartmental shuttle for peroxisome proliferator activated receptor gamma agonists in cultured cell. Biochim. Biophys. Acta 1761 (2006) 172-181
2. Aoyama T., Peters J.M., Iritani N., Nakajima T., Furihata K., Hashimoto T., and Gonzalez F.J. Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha). J. Biol. Chem. 273 (1998) 5678-5684
3. Bellinger D.A., Merricks E.P., and Nichols T.C. Swine models of type 2 diabetes mellitus: insulin resistance, glucose tolerance, and cardiovascular complications. ILAR J. 47 (2006) 243-258
4. Bernlohr D.A., Angus C.W., Lane M.D., Bolanowski M.A., and Kelly Jr. T.J. Expression of specific mRNAs during adipose differentiation: identification of an mRNA encoding a homologue of myelin P2 protein. Proc. Natl. Acad. Sci. U. S. A. 81 (1984) 5468-5472
5. Bernlohr D.A., Bolanowski M.A., Kelly Jr. T.J., and Lane M.D. Evidence for an increase in transcription of specific mRNAs during differentiation of 3T3-L1 preadipocytes. J. Biol. Chem. 260 (1985) 5563-5567
6. Bernlohr D.A., Doering T.L., Kelly Jr. T.J., and Lane M.D. Tissue specific expression of p422 protein, a putative lipid carrier, in mouse adipocytes. Biochem. Biophys. Res. Commun. 132 (1985) 850-855
7. Bernlohr D.A., Coe N.R., Simpson M.A., and Hertzel A.V. Regulation of gene expression in adipose cells by polyunsaturated fatty acids. Adv. Exp. Med. Biol. 422 (1997) 145-156
8. Boord J.B., Maeda K., Makowski L., Babaev V.R., Fazio S., Linton M.F., and Hotamisligil G.S. Combined adipocyte-macrophage fatty acid-binding protein deficiency improves metabolism, atherosclerosis, and survival in apolipoprotein E-deficient mice. Circulation 110 (2004) 1492-1498
9. Cao H., Maeda K., Gorgun C.Z., Kim H.J., Park S.Y., Shulman G.I., Kim J.K., and Hotamisligil G.S. Regulation of metabolic responses by adipocyte/macrophage fatty acid-binding proteins in leptin-deficient mice. Diabetes 55 (2006) 1915-1922
10. Chawla A., and Lazar M.A. Peroxisome proliferator and retinoid signaling pathways co-regulate preadipocyte phenotype and survival. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 1786-1790
11. Chen C.H., Lin E.C., Cheng W.T., Sun H.S., Mersmann H.J., and Ding S.T. Abundantly expressed genes in pig adipose tissue: an expressed sequence tag approach. J. Anim. Sci. 84 (2006) 2673-2683
12. Chmurzynska A. The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism. J. Appl. Genet. 47 (2006) 39-48
13. Cock T.A., Houten S.M., and Auwerx J. Peroxisome proliferator-activated receptor-gamma: too much of a good thing causes harm. EMBO Rep. 5 (2004) 142-147
14. Coe N.R., Simpson M.A., and Bernlohr D.A. Targeted disruption of the adipocyte lipid-binding protein (aP2 protein) gene impairs fat cell lipolysis and increases cellular fatty acid levels. J. Lipid Res. 40 (1999) 967-972
15. Daikoku T., Shinohara Y., Shima A., Yamazaki N., and Terada H. Dramatic enhancement of the specific expression of the heart-type fatty acid binding protein in rat brown adipose tissue by cold exposure. FEBS Lett. 410 (1997) 383-386
16. Ding C., and Cantor C.R. A high-throughput gene expression analysis technique using competitive PCR and matrix-assisted laser desorption ionization time-of-flight MS. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 3059-3064
17. Ding S.T., McNeel R.L., and Mersmann H.J. Expression of porcine adipocyte transcripts: tissue distribution and differentiation in vitro and in vivo. Comp. Biochem. Physiol., Part B Biochem. Mol. Biol. 123 (1999) 307-318
18. Erol E., Kumar L.S., Cline G.W., Shulman G.I., Kelly D.P., and Binas B. Liver fatty acid binding protein is required for high rates of hepatic fatty acid oxidation but not for the action of PPARalpha in fasting mice. FASEB J. 18 (2004) 347-349
19. Fajas L., Landsberg R.L., Huss-Garcia Y., Sardet C., Lees J.A., and Auwerx J. E2Fs regulate adipocyte differentiation. Dev. Cell 3 (2002) 39-49
20. Gardan D., Louveau I., and Gondret F. Adipocyte- and heart-type fatty acid binding proteins are both expressed in subcutaneous and intramuscular porcine (Sus scrofa) adipocytes. Comp. Biochem. Physiol., Part B Biochem. Mol. Biol. 148 (2007) 14-19
21. Gerbens F., van Erp A.J., Harders F.L., Verburg F.J., Meuwissen T.H., Veerkamp J.H., and te Pas M.F. Effect of genetic variants of the heart fatty acid-binding protein gene on intramuscular fat and performance traits in pigs. J. Anim. Sci. 77 (1999) 846-852
22. Gerbens F., Verburg F.J., Van Moerkerk H.T., Engel B., Buist W., Veerkamp J.H., and te Pas M.F. Associations of heart and adipocyte fatty acid-binding protein gene expression with intramuscular fat content in pigs. J. Anim. Sci. 79 (2001) 347-354
23. Glatz J.F., and van der Vusse G.J. Cellular fatty acid-binding proteins: their function and physiological significance. Prog. Lipid Res. 35 (1996) 243-282
24. Glatz J.F., Schaap F.G., Binas B., Bonen A., van der Vusse G.J., and Luiken J.J. Cytoplasmic fatty acid-binding protein facilitates fatty acid utilization by skeletal muscle. Acta Physiol. Scand. 178 (2003) 367-371
25. Hertzel A.V., and Bernlohr D.A. Regulation of adipocyte gene expression by polyunsaturated fatty acids. Mol. Cell. Biochem. 188 (1998) 33-39
26. Hertzel A.V., Smith L.A., Berg A.H., Cline G.W., Shulman G.I., Scherer P.E., and Bernlohr D.A. Lipid metabolism and adipokine levels in fatty acid-binding protein null and transgenic mice. Am. J. Physiol., Endocrinol. Metabol. 290 (2006) E814-E823
27. Hotamisligil G.S., Johnson R.S., Distel R.J., Ellis R., Papaioannou V.E., and Spiegelman B.M. Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein. Science 274 (1996) 1377-1379
28. Issemann I., Prince R., Tugwood J., and Green S. A role for fatty acids and liver fatty acid binding protein in peroxisome proliferation?. Biochem. Soc. Trans. 20 (1992) 824-827
29. Jiang Y.Z., Li X.W., and Yang G.X. Sequence characterization, tissue-specific expression and polymorphism of the porcine (Sus scrofa) liver-type fatty acid binding protein gene. Yichuan Xuebao 33 (2006) 598-606
30. Kawabe K., Saegusa H., Seto K., Urabe H., and Motojima K. Peroxisome proliferator-activated receptor alpha and its response element are required but not sufficient for transcriptional activation of the mouse heart-type fatty acid binding protein gene. Int. J. Biochem. Cell Biol. 37 (2005) 1534-1546
31. Landrier J.F., Thomas C., Grober J., Duez H., Percevault F., Souidi M., Linard C., Staels B., and Besnard P. Statin induction of liver fatty acid-binding protein (L-FABP) gene expression is peroxisome proliferator-activated receptor-alpha-dependent. J. Biol. Chem. 279 (2004) 45512-45518
32. Li B., Zerby H.N., and Lee K. Heart fatty acid binding protein is upregulated during porcine adipocyte development. J. Anim. Sci. 85 (2007) 1651-1659
33. Maeda K., Uysal K.T., Makowski L., Gorgun C.Z., Atsumi G., Parker R.A., Bruning J., Hertzel A.V., Bernlohr D.A., and Hotamisligil G.S. Role of the fatty acid binding protein mal1 in obesity and insulin resistance. Diabetes 52 (2003) 300-307
34. Maeda K., Cao H., Kono K., Gorgun C.Z., Furuhashi M., Uysal K.T., Cao Q., Atsumi G., Malone H., Krishnan B., Minokoshi Y., Kahn B.B., Parker R.A., and Hotamisligil G.S. Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes. Cell Metab. 1 (2005) 107-119
35. Motojima K. Differential effects of PPARalpha activators on induction of ectopic expression of tissue-specific fatty acid binding protein genes in the mouse liver. Int. J. Biochem. Cell Biol. 32 (2000) 1085-1092
36. Pelton P.D., Zhou L., Demarest K.T., and Burris T.P. PPARgamma activation induces the expression of the adipocyte fatty acid binding protein gene in human monocytes. Biochem. Biophys. Res. Commun. 261 (1999) 456-458
37. Poirier H., Braissant O., Niot I., Wahli W., and Besnard P. 9-cis-retinoic acid enhances fatty acid-induced expression of the liver fatty acid-binding protein gene. FEBS Lett. 412 (1997) 480-484
38. Ramirez-Zacarias J.L., Castro-Munozledo F., and Kuri-Harcuch W. Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O. Histochemistry 97 (1992) 493-497
39. Rangwala S.M., and Lazar M.A. Transcriptional control of adipogenesis. Annu. Rev. Nutr. 20 (2000) 535-559
40. Ren D., Collingwood T.N., Rebar E.J., Wolffe A.P., and Camp H.S. PPARgamma knockdown by engineered transcription factors: exogenous PPARgamma2 but not PPARgamma1 reactivates adipogenesis. Genes Dev. 16 (2002) 27-32
41. Saladin R., Fajas L., Dana S., Halvorsen Y.D., Auwerx J., and Briggs M. Differential regulation of peroxisome proliferator activated receptor gamma1 (PPARgamma1) and PPARgamma2 messenger RNA expression in the early stages of adipogenesis. Cell Growth Differ. 10 (1999) 43-48
42. Schachtrup C., Emmler T., Bleck B., Sandqvist A., and Spener F. Functional analysis of peroxisome-proliferator-responsive element motifs in genes of fatty acid-binding proteins. Biochem. J. 382 (2004) 239-245
43. Scheja L., Makowski L., Uysal K.T., Wiesbrock S.M., Shimshek D.R., Meyers D.S., Morgan M., Parker R.A., and Hotamisligil G.S. Altered insulin secretion associated with reduced lipolytic efficiency in aP2-/- mice. Diabetes 48 (1999) 1987-1994
44. Schoonjans K., Staels B., and Auwerx J. The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation. Biochim. Biophys. Acta 1302 (1996) 93-109
45. Schroeder F., Atshaves B.P., Starodub O., Boedeker A.L., Smith III R.R., Roths J.B., Foxworth W.B., and Kier A.B. Expression of liver fatty acid binding protein alters growth and differentiation of embryonic stem cells. Mol. Cell. Biochem. 219 (2001) 127-138
46. Shaughnessy S., Smith E.R., Kodukula S., Storch J., and Fried S.K. Adipocyte metabolism in adipocyte fatty acid binding protein knockout mice (aP2-/-) after short-term high-fat feeding: functional compensation by the keratinocyte [correction of keritinocyte] fatty acid binding protein. Diabetes 49 (2000) 904-911
47. Shen W.J., Sridhar K., Bernlohr D.A., and Kraemer F.B. Interaction of rat hormone-sensitive lipase with adipocyte lipid-binding protein. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 5528-5532
48. Siegenthaler G., Hotz R., Chatellard-Gruaz D., Didierjean L., Hellman U., and Saurat J.H. Purification and characterization of the human epidermal fatty acid-binding protein: localization during epidermal cell differentiation in vivo and in vitro. Biochem. J. 302 (1994) 363-371
49. Smith A.J., Sanders M.A., Thompson B.R., Londos C., Kraemer F.B., and Bernlohr D.A. Physical association between the adipocyte fatty acid-binding protein and hormone-sensitive lipase: a fluorescence resonance energy transfer analysis. J. Biol. Chem. 279 (2004) 52399-52405
50. Spiegelman B.M., Frank M., and Green H. Molecular cloning of mRNA from 3T3 adipocytes. Regulation of mRNA content for glycerophosphate dehydrogenase and other differentiation-dependent proteins during adipocyte development. J. Biol. Chem. 258 (1983) 10083-10089
51. Spurlock M.E., and Gabler N.K. The development of porcine models of obesity and the metabolic syndrome. J. Nutr. 138 (2008) 397-402
52. Tan N.S., Shaw N.S., Vinckenbosch N., Liu P., Yasmin R., Desvergne B., Wahli W., and Noy N. Selective cooperation between fatty acid binding proteins and peroxisome proliferator-activated receptors in regulating transcription. Mol. Cell. Biol. 22 (2002) 5114-5127
53. Tontonoz P., Graves R.A., Budavari A.I., Erdjument-Bromage H., Lui M., Hu E., Tempst P., and Spiegelman B.M. Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and RXR alpha. Nucleic Acids Res. 22 (1994) 5628-5634
54. Uysal K.T., Scheja L., Wiesbrock S.M., Bonner-Weir S., and Hotamisligil G.S. Improved glucose and lipid metabolism in genetically obese mice lacking aP2. Endocrinology 141 (2000) 3388-3396
55. Wolfrum C., Borrmann C.M., Borchers T., and Spener F. Fatty acids and hypolipidemic drugs regulate peroxisome proliferator-activated receptors alpha- and gamma-mediated gene expression via liver fatty acid binding protein: a signaling path to the nucleus. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 2323-2328