An immunohistochemical study of the endocrine pancreas of the African ice rat, Otomys sloggetti robertsi

Acta Histochemica

Volumn 110, Issue 4, 2008, Pages 294-301

  Gustavsen, Carsten R ^a   Pillay, Neville ^b   Heller, R Scott ^a  

^a HAGEDORN RESEARCH INSTITUTE   (Denmark)

^b UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

Glucagon; Insulin; Otomys; Pancreas; PDX 1; Somatostatin; Transcription factors

Indexed keywords

COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; CYTOKERATIN; GHRELIN; GLUCAGON; INSULIN; PANCREAS POLYPEPTIDE; PEPTIDE YY; SOMATOSTATIN; TRANSCRIPTION FACTOR MAFA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL TYPE; CONTROLLED STUDY; CYTOARCHITECTURE; ENDOTHELIUM CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; NONHUMAN; PANCREAS ISLET; PROTEIN LOCALIZATION; RAT;

AFRICA; ANIMALS; HOMEODOMAIN PROTEINS; HORMONES; IMMUNOHISTOCHEMISTRY; ISLETS OF LANGERHANS; MURINAE; TRANSCRIPTION FACTORS;

ANIMALIA; MURINAE; MUROIDEA; OTOMYS; OTOMYS SLOGGETTI; RATTUS; RODENTIA;

EID: 49949152251     PISSN: 00651281     EISSN: 16180372     Source Type: Journal    
DOI: 10.1016/j.acthis.2007.11.003     Document Type: Article

References (32)

1. Ahlgren U., Jonsson J., Jonsson L., Simu K., and Edlund H. Beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes. Genes Dev 12 (1998) 1763-1768
2. Alli-Rachedi A., Varndell I.M., Adrian T.E., Gapp D.A., van Noorden S., Bloom S.R., et al. Peptide YY (PYY) immunoreactivity is co-stored with glucagon-related immunoreactants in endocrine cells of the gut and pancreas. Histochemistry 80 (1984) 487-491
3. Artner I., Le Lay J., Hang Y., Elghazi L., Schisler J.C., Henderson E., et al. MafB: an activator of the glucagon gene expressed in developing islet α- and β-cells. Diabetes 55 (2006) 297-304
4. Böttcher G., Sjöberg J., Ekman R., Håkanson R., and Sundler F. Peptide YY in the mammalian pancreas: immunocytochemical localization and immunochemical characterization. Regul Peptides 43 (1993) 115-130
5. De Vroede M., Foriers A., Van de Winkel M., Madsen O., and Pipeleers D. Presence of islet amyloid polypeptide in rat islet B and D cells determines parallelism and dissociation between rat pancreatic islet amyloid polypeptide and insulin content. Biochem Biophys Res Commun 182 (1992) 886-893
6. Donev S., Petkov P., Marquie G., Duhault J., and Jablenska R. Immunohistochemical investigations of the endocrine pancreas in normoglycemic sand rats (Psammomys obesus). Acta Diabetol Latina 26 (1989) 309-313
7. Heller R.S., Jenny M., Collombat P., Mansouri A., Tomasetto C., Madsen O.D., et al. Genetic determinants of pancreatic epsilon-cell development. Dev Biol 286 (2005) 217-224
8. Jackerott M., Øster A., and Larsson L.I. PYY in developing murine islet cells: comparisons to development of islet hormones, NPY, and BrdU incorporation. J Histochem Cytochem 44 (1996) 809-817
9. Jensen P.B., Kristensen P., Clausen J.T., Judge M.E., Hastrup S., Thim L., et al. The hypothalamic satiety peptide CART is expressed in anorectic and non-anorectic pancreatic islet tumors and in the normal islet of Langerhans. FEBS Lett 447 (1999) 139-143
10. Jonsson J., Carlsson L., Edlund T., and Edlund H. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371 (1994) 606-609
11. Kataoka K. Multiple mechanisms and functions of Maf transcription factors in the regulation of tissue-specific genes. J Biochem 141 (2007) 775-781
12. Killick D.J.B. The Afro-alpine region. In: Werger M.J.A. (Ed). Biogeography and ecology of southern Africa (1978), Junk, The Hague 515-560
13. Ku S.K., Lee H.S., and Lee J.H. An immunohistochemical study on the pancreatic endocrine cells of the C57BL/6 mouse. J Vet Sci 3 (2002) 327-333
14. Leibowitz G., Ferber S., Apelqvist A., Edlund H., Gross D.J., Cerasi E., et al. IPF1/PDX1 deficiency and beta-cell dysfunction in Psammomys obesus, an animal with type 2 diabetes. Diabetes 50 (2001) 1799-1806
15. Murtaugh L.C. Pancreas and beta-cell development: from the actual to the possible. Development 134 (2007) 427-438
16. Musser G., and Carleton M. Superfamily Muroidea. In: Wilson D.E., and Reeder D.M. (Eds). Mammal species of the world (2005), The Johns Hopkins University Press, Baltimore and London
17. Nelson S.Y., Shamila Y., and Michael P. Zebrafish pdx1 morphant displays defects in pancreas development and digestive organ chirality, and potentially identifies a multipotent pancreas progenitor cell. Genesis 30 (2001) 137-140
18. Orci L., Baetens D., Ravazzola M., Stefan Y., and Malaisse-Lagae F. Pancreatic polypeptide islets and glucagon islets : distinct topographic distribution in rat pancreas. C R Acad Sci Hebd Seances Acad Sci D 283 (1976) 1213-1216
19. Perrin M.R., and Curtis B.A. Comparative morphology of the digestive track of 19 species of southern African myomorph rodents in relation to diet and evolution. S Afr J Zool 15 (1980) 22-33
20. Prado C.L., Pugh-Bernard A.E., Elghazi L., Sosa-Pineda B., and Sussel L. Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development. Proc Nat Acad Sci USA 101 (2004) 2924-2929
21. Reddy S.N., Bibby N.J., and Elliott R.B. Cellular distribution of insulin, glucagon, pancreatic polypeptide hormone and somatostatin in the fetal and adult pancreas of the guinea pig: a comparative immunohistochemical study. Eur J Cell Biol 38 (1985) 301-305
22. Schwaibold U., and Pillay N. The gut morphology of the African ice rat, Otomys sloggetti robertsi, shows adaptations to cold environments and sex-specific seasonal variation. J Comp Physiol [B] 173 (2003) 653-659
23. Shimizu K., Kato Y., Shiratori K., Ding Y., Song Y., Furlanetto R., et al. Evidence for the existence of CCK-producing cells in rat pancreatic islets. Endocrinology 139 (1998) 389-396
24. Shimizu K., Shiratori K., Sakayori N., Kobayashi M., and Hayashi N. Expression of cholecystokinin in the pancreas during development. Pancreas 19 (1999) 98-104
25. Stoffers D.S., Zinkin N.T., Stanojevic V., Clarke W.L., and Habener J.F. Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nat Genet 15 (1997) 106-110
26. Sussel L., Kalamaras J., Hartigan-O'Connor D.J., Meneses J.J., Pedersen R.A., Rubenstein J.L.R., et al. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic β cells. Development 125 (1998) 2213-2221
27. Thomas M.K., Devon O.N., Lee J.H., Peter A., Schlosser D.A., Tenser M.S., et al. Development of diabetes mellitus in aging transgenic mice following suppression of pancreatic homeoprotein IDX-1. J Clin Invest 108 (2001) 319-329
28. Upchurch B.H., Aponte G.W., and Leiter A.B. Expression of peptide YY in all four islet cell types in the developing mouse pancreas suggests a common peptide YY-producing progenitor. Development 120 (1994) 245-252
29. Vedtofte L., Bödvarsdóttir T.B., Karlsen A.E., and Heller R.S. Developmental biology of the Psammomys obesus pancreas: cloning and expression of the Neurogenin-3 gene. J Histochem Cytochem 55 (2007) 97-104
30. Wierup N., Kuhar M., Nilsson B.O., Mulder H., Ekblad E., and Sundler F. Cocaine- and amphetamine-regulated transcript (CART) is expressed in several islet cell types during rat development. J Histochem Cytochem 53 (2004) 169-177
31. Yamada J., Campos V.J.M., Kitamura N., Pacheco A.C., Yamashita T., and Yanaihara N. An immunohistochemical study of endocrine cells in the pancreas of Caiman latirostris (Alligatorinae), with special reference to pancreatic motilin cells. Biomed Res 7 (1986) 199-208
32. Yukawa M., Takeuchi T., Watanabe T., and Kitamura S. Proportions of various endocrine cells in the pancreatic islets of wood mice (Apodemus speciosus). Anat Histol Embryol 28 (1999) 13-16