A p38 mitogen-activated protein kinase inhibitor protects against renal damage in a non-heart-beating donor model

American Journal of Physiology - Renal Physiology

Volumn 295, Issue 1, 2008, Pages

  Doucet, Carole ^a   Milin, Serge ^a   Favreau, Frederic ^a   Desurmont, Thibault ^a   Manguy, Emilie ^a,b   Hébrard, William ^b   Yamamoto, Yuriyo ^c   Mauco, Gérard ^a   Eugene, Michel ^a   Papadopoulos, Vassilios ^d   Hauet, Thierry ^a,b,e   Goujon, Jean Michel ^a,e  

^a UNIVERSITÉ DE POITIERS   (France)

^b CEMAGREF   (France)

^c ASTELLAS PHARMA INC   (Japan)

^d GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^e POITIERS UNIVERSITY HOSPITAL   (France)

Author keywords

Angiogenesis; Ischemia reperfusion injury; Renal fibrosis; Tissue repair

Indexed keywords

1 [7 (4 FLUOROPHENYL) 1,2,3,4 TETRAHYDRO 8 (4 PYRIDYL)PYRAZOLO[5,1 C][1,2,4]TRIAZIN 2 YL] 2 PHENYLETHANEDIONE; BENZODIAZEPINE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; VASCULOTROPIN; VIMENTIN; ENZYME INHIBITOR; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL DAMAGE; CELL REGENERATION; COLD ISCHEMIA; CONTROLLED STUDY; CONVALESCENCE; DRUG MECHANISM; HEART BEAT; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; KIDNEY DONOR; KIDNEY FIBROSIS; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY PROXIMAL TUBULE; KIDNEY TRANSPLANTATION; MALE; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENAL PROTECTION; SURVIVAL; SWINE; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; BLOOD; DRUG ANTAGONISM; DRUG EFFECT; FIBROSIS; KIDNEY DISEASE; PATHOLOGY; PATHOPHYSIOLOGY; REPERFUSION INJURY;

ANIMALS; CELL ADHESION; ENZYME INHIBITORS; FIBROSIS; INTERLEUKIN-1BETA; KIDNEY DISEASES; KIDNEY TRANSPLANTATION; KIDNEY TUBULES, PROXIMAL; MALE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRAZOLES; PYRIDINES; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; REPERFUSION INJURY; SWINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 49949113944     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00252.2007     Document Type: Article

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