Effects of adding p38 mitogen-activated protein-kinase inhibitor to celsior solution in canine heart transplantation from non-heart-beating donors

Transplantation

Volumn 77, Issue 2, 2004, Pages 286-292

  Koike, Norimasa ^a   Takeyoshi, Izumi ^a   Ohki, Shigeru ^a   Tokumine, Masahiko ^a   Matsumoto, Koshi ^b   Morishita, Yasuo ^a  

^a GUNMA UNIVERSITY   (Japan)

^b NIPPON MEDICAL SCHOOL MUSASHI KOSUGI HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 [7 (4 FLUOROPHENYL) 1,2,3,4 TETRAHYDRO 8 (4 PYRIDYL)PYRAZOLO[5,1 C][1,2,4]TRIAZIN 2 YL] 2 PHENYLETHANEDIONE; CELSIOR; DRUG ADDITIVE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; DOG; DRUG EFFECT; ENZYME ACTIVATION; HEART ARREST; HEART BEAT; HEART FUNCTION; HEART GRAFT; HEART LEFT VENTRICLE PRESSURE; HEART OUTPUT; HEART PERFORMANCE; HEART TRANSPLANTATION; HISTOPATHOLOGY; ISCHEMIA; NONHUMAN; ORGAN DONOR; PRIORITY JOURNAL; REPERFUSION INJURY;

ANIMALS; CARDIOPLEGIC SOLUTIONS; DISACCHARIDES; DOGS; ELECTROLYTES; ENZYME ACTIVATION; ENZYME INHIBITORS; GLUTAMATES; GLUTATHIONE; GROWTH INHIBITORS; HEART; HEART ARREST; HEART TRANSPLANTATION; HISTIDINE; MANNITOL; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, ANIMAL; MYOCARDIAL ISCHEMIA; MYOCARDIUM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRAZOLES; PYRIDINES; REPERFUSION INJURY;

EID: 0742269909     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000101039.12835.A4     Document Type: Article

References (29)

1. Azuma H, Heeman UW, Tullius SG, et al. Cytokines and adhesion molecules in chronic rejection. Clin Transplant 1994; 8: 168.
2. Meldrum DR, Cleveland JC, Cain BS, et al. Increased myocardial TNF-α in a crystalloid perfused model of cardiac ischemia-reperfusion injury. Ann Thorac Surg 1998; 65: 439.
3. Yue TL, Wang C, Gu JL, et al. Inhibition of extracellular signal-regulated kinase enhances ischemia/reoxygenation-induced apoptosis in cultured cardiac myocytes and exaggerates reperfusion injury in isolated perfused heart. Circ Res 2000; 86: 692.
4. Sugden PH, Clerk A. "Stress-responsive" mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium. Circ Res 1998; 83: 345.
5. Bogoyevitch MA, Gillespie-Brown J, Ketterman AJ, et al. Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart: p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion. Circ Res 1996; 79: 162.
6. Cowley S, Paterson H, Kemp P, et al. Activation of MAP kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 1994; 77: 841.
7. Mansour SJ, Matten WT, Hermann AS, et al. Transformation of mammalian cells by constitutively active MAP kinase. Science 1994; 265: 966.
8. Mackay K, Mochly-Rosen D. An inhibitor of p38 mitogen-activated protein kinase protects neonatal cardiac myocytes from ischemia. J Biol Chem 1999; 274: 6272.
9. Raingeaud J, Gupta S, Rogers JS, et al. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem 1995; 270: 7420.
10. Lee JC, Young PR. Role of CSB/p38/RK stress response kinase in LPS and cytokine signaling mechanisms. J Leukoc Biol 1996; 59: 152.
11. Yamamoto N, Sakai F, Yamazaki H, et al. Effect of FR167653, a cytokine suppressive agent, on endotoxin-induced disseminated intravascular coagulation. Eur J Pharmacol 1996; 314: 137.
12. Yoshinari D, Takeyoshi I, Kobayashi M, et al. Effects of a p38 mitogen-activated protein kinase inhibitor as an additive to University of Wisconsin solution on reperfusion injury in liver transplantation. Transplantation 2001; 72: 22.
13. Lower RR, Shumway NE. Studies on orthotopic homotransplantations of the canine heart. Surg Forum 1960; 11: 18.
14. Morishita Y. Orthotopic allotransplantation of the preserved canine heart. Acta Med Univ Kagoshima 1974; 16: 107.
15. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248.
16. Fukuhara T. Histochemical, ultrastructural and cytochemical study of reperfusion effect on ischemic myocardial injury. Jpn Circ J 1985; 49: 432.
17. Schaper J, Schaper W. Reperfusion of ischemic myocardium: ultrastructural and histochemical aspects. J Am Coll Cardiol 1983; 1: 1037.
18. Ma XL, Kumar S, Gao F, et al. Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion. Circulation 1999; 99: 1685.
19. Zechner D, Thuerauf DJ, Hanford DS, et al. A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression. J Cell Biol 1997; 139: 115.
20. Shimizu N, Yoshiyama N, Omura T, et al. Activation of mitogen-activated protein kinases and activator protein-1 in myocardial infarction in rats. Cardiovasc Res 1998; 38: 116.
21. Cain BS, Meldrum DR, Meng X, et al. P38-MAPK inhibition decreases TNF-α production and enhances postischemic human myocardial function. J Surg Res 1999; 83: 7.
22. Guarnieri C, Flamigni F, Caldarera CM. Role of oxygen in the cellular damage induced by re-oxygenation of hypoxic heart. J Mol Cell Cardiol 1980;12:797.
23. Lee JC, Laydon JT, McDonnell PC, et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994; 372: 739.
24. Koyano T, Takeyoshi I, Takahashi T, et al. Effects of FR167653 on ischemia-reperfusion injury: evaluation through preservation and transplantation in canine hearts. J Heart Lung Transplant 1998; 17: 1247.
25. Kawashima Y, Takeyoshi I, Otani Y, et al. FR167653 attenuates ischemia and reperfusion injury of the rat lung with suppressing p38 mitogen-activated protein kinase. J Heart Lung Transplant 2001; 20: 568.
26. Kobayashi J, Takeyoshi I, Ohwada S, et al. The effect of FR167653 in extended liver resection with ischemia in dogs. Hepatology 1998; 28: 459.
27. Enslen H, Raingeaud J, Davis R. Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase MKK3 and MKK6. J Biol Chem 1998; 273: 1741.
28. Bethencourt DM, Laks H. Importance of edema and compliance changes during 24 hours of preservation of the dog heart. J Thorac Cardiovasc Surg 1981; 81: 440.
29. Clerk A, Sugden P. The p38-MAPK inhibitor, SB203580, inhibits cardiac stress-activated protein kinase/c-Jun N-terminal kinases (SPAKs/JNKs). FEBS Lett 1998; 426: 93.