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Volumn 24, Issue 9, 2008, Pages 907-917

Molecular recognition of the NPY hormone family by their receptors

Author keywords

Ligands; Neuropeptide Y; Y receptor

Indexed keywords

ARGININE; ASPARTIC ACID; LIGAND; NEUROPEPTIDE Y; NEUROPEPTIDE Y1 RECEPTOR; NEUROPEPTIDE Y2 RECEPTOR; NEUROPEPTIDE Y4 RECEPTOR; NEUROPEPTIDE Y5 RECEPTOR; PANCREAS POLYPEPTIDE; PEPTIDE YY;

EID: 49949111829     PISSN: 08999007     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nut.2008.06.025     Document Type: Review
Times cited : (61)

References (41)
  • 1
    • 0020419772 scopus 로고
    • Neuropeptide Y. complete amino acid sequence of the brain peptide
    • Tatemoto K. Neuropeptide Y. complete amino acid sequence of the brain peptide. Proc Natl Acad Sci U S A 79 (1982) 5485-5489
    • (1982) Proc Natl Acad Sci U S A , vol.79 , pp. 5485-5489
    • Tatemoto, K.1
  • 2
    • 4344595580 scopus 로고    scopus 로고
    • NPY and cohorts in regulating appetite, obesity and metabolic syndrome: beneficial effects of gene therapy
    • Kalra S.P., and Kalra P.S. NPY and cohorts in regulating appetite, obesity and metabolic syndrome: beneficial effects of gene therapy. Neuropeptides 38 (2004) 201-211
    • (2004) Neuropeptides , vol.38 , pp. 201-211
    • Kalra, S.P.1    Kalra, P.S.2
  • 3
    • 0000613769 scopus 로고
    • Isolation and characterization of peptide YY (PYY), a candidate gut hormone that inhibits pancreatic exocrine secretion
    • Tatemoto K. Isolation and characterization of peptide YY (PYY), a candidate gut hormone that inhibits pancreatic exocrine secretion. Proc Natl Acad Sci U S A 79 (1982) 2514-2518
    • (1982) Proc Natl Acad Sci U S A , vol.79 , pp. 2514-2518
    • Tatemoto, K.1
  • 4
    • 0036161876 scopus 로고    scopus 로고
    • Distribution of pancreatic polypeptide and peptide YY
    • Ekblad E., and Sundler F. Distribution of pancreatic polypeptide and peptide YY. Peptides 23 (2002) 251-261
    • (2002) Peptides , vol.23 , pp. 251-261
    • Ekblad, E.1    Sundler, F.2
  • 5
    • 0016708363 scopus 로고
    • Isolation and characterization of a new pancreatic polypeptide hormone
    • Kimmel J.R., Hayden L.J., and Pollock H.G. Isolation and characterization of a new pancreatic polypeptide hormone. J Biol Chem 250 (1975) 9369-9376
    • (1975) J Biol Chem , vol.250 , pp. 9369-9376
    • Kimmel, J.R.1    Hayden, L.J.2    Pollock, H.G.3
  • 6
    • 0027448057 scopus 로고
    • The pancreatic polypeptide (PP-fold) family: gastrointestinal, vascular, and feeding behavioral implications
    • Hazelwood R.L. The pancreatic polypeptide (PP-fold) family: gastrointestinal, vascular, and feeding behavioral implications. Proc Soc Exp Biol Med 202 (1993) 44-63
    • (1993) Proc Soc Exp Biol Med , vol.202 , pp. 44-63
    • Hazelwood, R.L.1
  • 7
    • 0019413468 scopus 로고
    • X-ray analysis (1. 4-A resolution) of avian pancreatic polypeptide: Small globular protein hormone
    • Blundell T.L., Pitts J.E., Tickle I.J., Wood S.P., and Wu C.W. X-ray analysis (1. 4-A resolution) of avian pancreatic polypeptide: Small globular protein hormone. Proc Natl Acad Sci U S A 78 (1981) 4175-4179
    • (1981) Proc Natl Acad Sci U S A , vol.78 , pp. 4175-4179
    • Blundell, T.L.1    Pitts, J.E.2    Tickle, I.J.3    Wood, S.P.4    Wu, C.W.5
  • 11
    • 0038002089 scopus 로고    scopus 로고
    • Control of signalling efficacy by palmitoylation of the rat Y1 receptor
    • Holliday N.D., and Cox H.M. Control of signalling efficacy by palmitoylation of the rat Y1 receptor. Br J Pharmacol 139 (2003) 501-512
    • (2003) Br J Pharmacol , vol.139 , pp. 501-512
    • Holliday, N.D.1    Cox, H.M.2
  • 12
    • 0028097051 scopus 로고
    • Complete L-alanine scan of neuropeptide Y reveals ligands binding to Y1 and Y2 receptors with distinguished conformations
    • Beck-Sickinger A.G., Wieland H.A., Wittneben H., Willim K.D., Rudolf K., and Jung G. Complete L-alanine scan of neuropeptide Y reveals ligands binding to Y1 and Y2 receptors with distinguished conformations. Eur J Biochem 225 (1994) 947-958
    • (1994) Eur J Biochem , vol.225 , pp. 947-958
    • Beck-Sickinger, A.G.1    Wieland, H.A.2    Wittneben, H.3    Willim, K.D.4    Rudolf, K.5    Jung, G.6
  • 13
    • 34147109144 scopus 로고    scopus 로고
    • Receptor subtype-specific docking of Asp6.59 with C-terminal arginine residues in Y receptor ligands
    • Merten N., Lindner D., Rabe N., Rompler H., Morl K., Schoneberg T., and Beck-Sickinger A.G. Receptor subtype-specific docking of Asp6.59 with C-terminal arginine residues in Y receptor ligands. J Biol Chem 282 (2007) 7543-7551
    • (2007) J Biol Chem , vol.282 , pp. 7543-7551
    • Merten, N.1    Lindner, D.2    Rabe, N.3    Rompler, H.4    Morl, K.5    Schoneberg, T.6    Beck-Sickinger, A.G.7
  • 14
    • 20144372480 scopus 로고    scopus 로고
    • Extracellular loop 3 (EL3) and EL3-proximal transmembrane helix 7 of the mammalian type I and type II gonadotropin-releasing hormone (GnRH) receptors determine differential ligand selectivity to GnRH-I and GnRH-II
    • Li J.H., Choe H., Wang A.F., Maiti K., Wang C., Salam A., et al. Extracellular loop 3 (EL3) and EL3-proximal transmembrane helix 7 of the mammalian type I and type II gonadotropin-releasing hormone (GnRH) receptors determine differential ligand selectivity to GnRH-I and GnRH-II. Mol Pharmacol 67 (2005) 1099-1110
    • (2005) Mol Pharmacol , vol.67 , pp. 1099-1110
    • Li, J.H.1    Choe, H.2    Wang, A.F.3    Maiti, K.4    Wang, C.5    Salam, A.6
  • 15
    • 39649113864 scopus 로고    scopus 로고
    • Extracellular loop 3 (ECL3) and ECL3-proximal transmembrane domains VI and VII of the mesotocin and vasotocin receptors confer differential ligand selectivity and signaling activity
    • Cho H.J., Moon M.J., Kwon H.B., Hwang J.I., and Seong J.Y. Extracellular loop 3 (ECL3) and ECL3-proximal transmembrane domains VI and VII of the mesotocin and vasotocin receptors confer differential ligand selectivity and signaling activity. Gen Comp Endocrinol 156 (2008) 71-82
    • (2008) Gen Comp Endocrinol , vol.156 , pp. 71-82
    • Cho, H.J.1    Moon, M.J.2    Kwon, H.B.3    Hwang, J.I.4    Seong, J.Y.5
  • 17
    • 0028564783 scopus 로고
    • The first highly potent and selective non-peptide neuropeptide Y Y1 receptor antagonist: BIBP3226
    • Rudolf K., Eberlein W., Engel W., Wieland H.A., Willim K.D., Entzeroth M., et al. The first highly potent and selective non-peptide neuropeptide Y Y1 receptor antagonist: BIBP3226. Eur J Pharmacol 271 (1994) R11-R13
    • (1994) Eur J Pharmacol , vol.271
    • Rudolf, K.1    Eberlein, W.2    Engel, W.3    Wieland, H.A.4    Willim, K.D.5    Entzeroth, M.6
  • 18
    • 0034031434 scopus 로고    scopus 로고
    • Molecular characterization of the ligand-receptor interaction of the neuropeptide Y family
    • Cabrele C., and Beck-Sickinger A.G. Molecular characterization of the ligand-receptor interaction of the neuropeptide Y family. J Pept Sci 6 (2000) 97-122
    • (2000) J Pept Sci , vol.6 , pp. 97-122
    • Cabrele, C.1    Beck-Sickinger, A.G.2
  • 19
    • 0031566869 scopus 로고    scopus 로고
    • GW1229, a novel neuropeptide Y Y1 receptor antagonist, inhibits the vasoconstrictor effect on neuropeptide Y in the hamster microcirculation
    • Bitran M., Daniels A.J., and Boric M.P. GW1229, a novel neuropeptide Y Y1 receptor antagonist, inhibits the vasoconstrictor effect on neuropeptide Y in the hamster microcirculation. Eur J Pharmacol 319 (1997) 43-47
    • (1997) Eur J Pharmacol , vol.319 , pp. 43-47
    • Bitran, M.1    Daniels, A.J.2    Boric, M.P.3
  • 20
    • 0035837061 scopus 로고    scopus 로고
    • Highly selective and potent neuropeptide Y (NPY) Y1 receptor antagonists based on [Pro(30), Tyr(32), Leu(34)]NPY(28-36)-NH2 (BW1911U90)
    • Balasubramaniam A., Dhawan V.C., Mullins D.E., Chance W.T., Sheriff S., Guzzi M., et al. Highly selective and potent neuropeptide Y (NPY) Y1 receptor antagonists based on [Pro(30), Tyr(32), Leu(34)]NPY(28-36)-NH2 (BW1911U90). J Med Chem 44 (2001) 1479-1482
    • (2001) J Med Chem , vol.44 , pp. 1479-1482
    • Balasubramaniam, A.1    Dhawan, V.C.2    Mullins, D.E.3    Chance, W.T.4    Sheriff, S.5    Guzzi, M.6
  • 21
    • 0347296029 scopus 로고    scopus 로고
    • Analogues of neuropeptide Y containing beta-aminocyclopropane carboxylic acids are the shortest linear peptides that are selective for the Y1 receptor
    • Koglin N., Zorn C., Beumer R., Cabrele C., Bubert C., Sewald N., et al. Analogues of neuropeptide Y containing beta-aminocyclopropane carboxylic acids are the shortest linear peptides that are selective for the Y1 receptor. Angew Chem Int Ed Engl 42 (2003) 202-205
    • (2003) Angew Chem Int Ed Engl , vol.42 , pp. 202-205
    • Koglin, N.1    Zorn, C.2    Beumer, R.3    Cabrele, C.4    Bubert, C.5    Sewald, N.6
  • 22
    • 0028169253 scopus 로고
    • Acidic residues in extracellular loops of the human Y1 neuropeptide Y receptor are essential for ligand binding
    • Walker P., Munoz M., Martinez R., and Peitsch M.C. Acidic residues in extracellular loops of the human Y1 neuropeptide Y receptor are essential for ligand binding. J Biol Chem 269 (1994) 2863-2869
    • (1994) J Biol Chem , vol.269 , pp. 2863-2869
    • Walker, P.1    Munoz, M.2    Martinez, R.3    Peitsch, M.C.4
  • 23
    • 0029566092 scopus 로고
    • Ligand binding analysis of human neuropeptide Y1 receptor mutants expressed in E. coli
    • Munch G., Walker P., Shine J., and Herzog H. Ligand binding analysis of human neuropeptide Y1 receptor mutants expressed in E. coli. Receptors Channels 3 (1995) 291-297
    • (1995) Receptors Channels , vol.3 , pp. 291-297
    • Munch, G.1    Walker, P.2    Shine, J.3    Herzog, H.4
  • 24
    • 9444264701 scopus 로고    scopus 로고
    • Neuropeptide Y and the nonpeptide antagonist BIBP 3226 share an overlapping binding site at the human Y1 receptor
    • Sautel M., Rudolf K., Wittneben H., Herzog H., Martinez R., Munoz M., et al. Neuropeptide Y and the nonpeptide antagonist BIBP 3226 share an overlapping binding site at the human Y1 receptor. Mol Pharmacol 50 (1996) 285-292
    • (1996) Mol Pharmacol , vol.50 , pp. 285-292
    • Sautel, M.1    Rudolf, K.2    Wittneben, H.3    Herzog, H.4    Martinez, R.5    Munoz, M.6
  • 25
    • 30044440426 scopus 로고    scopus 로고
    • Re-evaluation of receptor-ligand interactions of the human neuropeptide Y receptor Y1: a site-directed mutagenesis study
    • Sjodin P., Holmberg S.K., Akerberg H., Berglund M.M., Mohell N., and Larhammar D. Re-evaluation of receptor-ligand interactions of the human neuropeptide Y receptor Y1: a site-directed mutagenesis study. Biochem J 393 (2006) 161-169
    • (2006) Biochem J , vol.393 , pp. 161-169
    • Sjodin, P.1    Holmberg, S.K.2    Akerberg, H.3    Berglund, M.M.4    Mohell, N.5    Larhammar, D.6
  • 27
    • 0035096988 scopus 로고    scopus 로고
    • Different binding sites for the neuropeptide Y Y1 antagonists 1229U91 and J-104870 on human Y1 receptors
    • Kannoa T., Kanatani A., Keen S.L., Arai-Otsuki S., Haga Y., Iwama T., et al. Different binding sites for the neuropeptide Y Y1 antagonists 1229U91 and J-104870 on human Y1 receptors. Peptides 22 (2001) 405-413
    • (2001) Peptides , vol.22 , pp. 405-413
    • Kannoa, T.1    Kanatani, A.2    Keen, S.L.3    Arai-Otsuki, S.4    Haga, Y.5    Iwama, T.6
  • 28
    • 0031042157 scopus 로고    scopus 로고
    • Modeling the G-protein-coupled neuropeptide Y Y1 receptor agonist and antagonist binding sites
    • Du P., Salon J.A., Tamm J.A., Hou C., Cui W., Walker M.W., et al. Modeling the G-protein-coupled neuropeptide Y Y1 receptor agonist and antagonist binding sites. Protein Eng 10 (1997) 109-117
    • (1997) Protein Eng , vol.10 , pp. 109-117
    • Du, P.1    Salon, J.A.2    Tamm, J.A.3    Hou, C.4    Cui, W.5    Walker, M.W.6
  • 30
    • 0037042210 scopus 로고    scopus 로고
    • Reciprocal mutations of neuropeptide Y receptor Y2 in human and chicken identify amino acids important for antagonist binding
    • Berglund M.M., Fredriksson R., Salaneck E., and Larhammar D. Reciprocal mutations of neuropeptide Y receptor Y2 in human and chicken identify amino acids important for antagonist binding. FEBS Lett 518 (2002) 5-9
    • (2002) FEBS Lett , vol.518 , pp. 5-9
    • Berglund, M.M.1    Fredriksson, R.2    Salaneck, E.3    Larhammar, D.4
  • 31
    • 0000448922 scopus 로고    scopus 로고
    • Characterisation of neuropeptide Y receptor subtypes by synthetic NPY analogues and by anti-receptor antibodies
    • Eckard C.P., Cabrele C., Wieland H.A., and Beck-Sickinger A. Characterisation of neuropeptide Y receptor subtypes by synthetic NPY analogues and by anti-receptor antibodies. Molecules 6 (2001) 448-467
    • (2001) Molecules , vol.6 , pp. 448-467
    • Eckard, C.P.1    Cabrele, C.2    Wieland, H.A.3    Beck-Sickinger, A.4
  • 33
    • 10244235259 scopus 로고    scopus 로고
    • Identification of a novel hypothalamic neuropeptide Y receptor associated with feeding behavior
    • Hu Y., Bloomquist B.T., Cornfield L.J., DeCarr L.B., Flores-Riveros J.R., Friedman L., et al. Identification of a novel hypothalamic neuropeptide Y receptor associated with feeding behavior. J Biol Chem 271 (1996) 26315-26319
    • (1996) J Biol Chem , vol.271 , pp. 26315-26319
    • Hu, Y.1    Bloomquist, B.T.2    Cornfield, L.J.3    DeCarr, L.B.4    Flores-Riveros, J.R.5    Friedman, L.6
  • 34
    • 0037328334 scopus 로고    scopus 로고
    • Molecular identification of the long isoform of the human neuropeptide Y Y5 receptor and pharmacological comparison with the short Y5 receptor isoform
    • Rodriguez M., Audinot V., Dromaint S., Macia C., Lamamy V., Beauverger P., et al. Molecular identification of the long isoform of the human neuropeptide Y Y5 receptor and pharmacological comparison with the short Y5 receptor isoform. Biochem J 369 (2003) 667-673
    • (2003) Biochem J , vol.369 , pp. 667-673
    • Rodriguez, M.1    Audinot, V.2    Dromaint, S.3    Macia, C.4    Lamamy, V.5    Beauverger, P.6
  • 35
    • 33947604569 scopus 로고    scopus 로고
    • Neuropeptide Y receptors; antisecretory control of intestinal epithelial function
    • Cox H.M. Neuropeptide Y receptors; antisecretory control of intestinal epithelial function. Auton Neurosci 133 (2007) 76-85
    • (2007) Auton Neurosci , vol.133 , pp. 76-85
    • Cox, H.M.1
  • 36
    • 0037338622 scopus 로고    scopus 로고
    • Recent developments in our understanding of the physiological role of PP-fold peptide receptor subtypes
    • Berglund M.M., Hipskind P.A., and Gehlert D.R. Recent developments in our understanding of the physiological role of PP-fold peptide receptor subtypes. Exp Biol Med (Maywood) 228 (2003) 217-244
    • (2003) Exp Biol Med (Maywood) , vol.228 , pp. 217-244
    • Berglund, M.M.1    Hipskind, P.A.2    Gehlert, D.R.3
  • 37
    • 0037172670 scopus 로고    scopus 로고
    • Ala31-Aib32: identification of the key motif for high affinity and selectivity of neuropeptide Y at the Y5-receptor
    • Cabrele C., Wieland H.A., Koglin N., Stidsen C., and Beck-Sickinger A.G. Ala31-Aib32: identification of the key motif for high affinity and selectivity of neuropeptide Y at the Y5-receptor. Biochemistry 41 (2002) 8043-8049
    • (2002) Biochemistry , vol.41 , pp. 8043-8049
    • Cabrele, C.1    Wieland, H.A.2    Koglin, N.3    Stidsen, C.4    Beck-Sickinger, A.G.5
  • 39
    • 34248342673 scopus 로고    scopus 로고
    • Effect of NPY5R antagonist MK-0557 on weight regain after very-low-calorie diet-induced weight loss
    • Erondu N., Wadden T., Gantz I., Musser B., Nguyen A.M., Bays H., et al. Effect of NPY5R antagonist MK-0557 on weight regain after very-low-calorie diet-induced weight loss. Obesity (Silver Spring) 15 (2007) 895-905
    • (2007) Obesity (Silver Spring) , vol.15 , pp. 895-905
    • Erondu, N.1    Wadden, T.2    Gantz, I.3    Musser, B.4    Nguyen, A.M.5    Bays, H.6
  • 40
    • 44449139101 scopus 로고    scopus 로고
    • GPC receptors and not ligands decide the binding mode in neuropeptide Y multireceptor/multiligand system
    • Lindner D., van Dieck J., Merten N., Morl K., Gunthe R., Hofmann H.J., and Beck-Sickinger A.G. GPC receptors and not ligands decide the binding mode in neuropeptide Y multireceptor/multiligand system. Biochem 47 (2008) 5905-5914
    • (2008) Biochem , vol.47 , pp. 5905-5914
    • Lindner, D.1    van Dieck, J.2    Merten, N.3    Morl, K.4    Gunthe, R.5    Hofmann, H.J.6    Beck-Sickinger, A.G.7


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