-
1
-
-
27644443615
-
Randomized, placebo-controlled trial of nonpegylated and pegylated forms of recombinant human alpha IFN 2a for suppression of dengue virus viremia in rhesus monkeys
-
Ajariyakhajorn C., Mammen M.P., Endy T.P., Gettayacamin M., Nisalak A., Nimmannitya S., and Libraty D.H. Randomized, placebo-controlled trial of nonpegylated and pegylated forms of recombinant human alpha IFN 2a for suppression of dengue virus viremia in rhesus monkeys. Antimicrob. Agents Chemother. 49 (2005) 4508-4514
-
(2005)
Antimicrob. Agents Chemother.
, vol.49
, pp. 4508-4514
-
-
Ajariyakhajorn, C.1
Mammen, M.P.2
Endy, T.P.3
Gettayacamin, M.4
Nisalak, A.5
Nimmannitya, S.6
Libraty, D.H.7
-
2
-
-
26444489068
-
Inhibition of IFN-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an IFN antagonist
-
Best S.M., Morris K.L., Shannon J.G., Robertson S.J., Mitzel D.N., Park G.S., Boer E., Wolfinbarger J.B., and Bloom M.E. Inhibition of IFN-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an IFN antagonist. J. Virol. 79 (2005) 12828-12839
-
(2005)
J. Virol.
, vol.79
, pp. 12828-12839
-
-
Best, S.M.1
Morris, K.L.2
Shannon, J.G.3
Robertson, S.J.4
Mitzel, D.N.5
Park, G.S.6
Boer, E.7
Wolfinbarger, J.B.8
Bloom, M.E.9
-
3
-
-
0001422785
-
Flaviviridae
-
Knipe D.M., and Howley P.M. (Eds), Lippincott-Williams and Wilkins, New York
-
Burke D.S., and Monath T.P. Flaviviridae. In: Knipe D.M., and Howley P.M. (Eds). Fields Virology. 4th ed. (2001), Lippincott-Williams and Wilkins, New York 1043-1125
-
(2001)
Fields Virology. 4th ed.
, pp. 1043-1125
-
-
Burke, D.S.1
Monath, T.P.2
-
4
-
-
35448972183
-
Differential effects of mutations in NS4B on West Nile Virus replication and inhibition of IFN signaling
-
Evans J.D., and Seeger C. Differential effects of mutations in NS4B on West Nile Virus replication and inhibition of IFN signaling. J. Virol. 81 (2007) 11809-11816
-
(2007)
J. Virol.
, vol.81
, pp. 11809-11816
-
-
Evans, J.D.1
Seeger, C.2
-
5
-
-
13744259524
-
West Nile virus inhibits the signal transduction pathway of alpha IFN
-
Guo J.T., Hayashi J., and Seeger C. West Nile virus inhibits the signal transduction pathway of alpha IFN. J. Virol. 79 (2005) 1343-1350
-
(2005)
J. Virol.
, vol.79
, pp. 1343-1350
-
-
Guo, J.T.1
Hayashi, J.2
Seeger, C.3
-
6
-
-
20444409731
-
Dengue virus type 2 antagonizes IFN-alpha but not IFN-gamma antiviral effect via down-regulating Tyk2-STAT signaling in the human dendritic cell
-
Ho L.J., Hung L.F., Weng C.Y., Wu W.L., Chou P., Lin Y.L., Chang D.M., Tai T.Y., and Lai J.H. Dengue virus type 2 antagonizes IFN-alpha but not IFN-gamma antiviral effect via down-regulating Tyk2-STAT signaling in the human dendritic cell. J. Immunol. 174 (2005) 8163-8172
-
(2005)
J. Immunol.
, vol.174
, pp. 8163-8172
-
-
Ho, L.J.1
Hung, L.F.2
Weng, C.Y.3
Wu, W.L.4
Chou, P.5
Lin, Y.L.6
Chang, D.M.7
Tai, T.Y.8
Lai, J.H.9
-
7
-
-
33750976374
-
5′-Triphosphate RNA is the ligand for RIG-I
-
Hornung V., Ellegast J., Kim S., Brzozka K., Jung A., Kato H., Poeck H., Akira S., Conzelmann K.K., Schlee M., Endres S., and Hartmann G. 5′-Triphosphate RNA is the ligand for RIG-I. Science 314 (2006) 994-997
-
(2006)
Science
, vol.314
, pp. 994-997
-
-
Hornung, V.1
Ellegast, J.2
Kim, S.3
Brzozka, K.4
Jung, A.5
Kato, H.6
Poeck, H.7
Akira, S.8
Conzelmann, K.K.9
Schlee, M.10
Endres, S.11
Hartmann, G.12
-
8
-
-
11244303498
-
Weapons of STAT destruction
-
Horvath C.M. Weapons of STAT destruction. Eur. J. Biochem. 271 (2004) 4621-4628
-
(2004)
Eur. J. Biochem.
, vol.271
, pp. 4621-4628
-
-
Horvath, C.M.1
-
9
-
-
0033554631
-
The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by IFN-alpha
-
Li S., Labrecque S., Gauzzi M.C., Cuddihy A.R., Wong A.H., Pellegrini S., Matlashewski G.J., and Koromilas A.E. The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by IFN-alpha. Oncogene 18 (1999) 5727-5737
-
(1999)
Oncogene
, vol.18
, pp. 5727-5737
-
-
Li, S.1
Labrecque, S.2
Gauzzi, M.C.3
Cuddihy, A.R.4
Wong, A.H.5
Pellegrini, S.6
Matlashewski, G.J.7
Koromilas, A.E.8
-
10
-
-
33744943788
-
Blocking of IFN-induced Jak-Stat signaling by Japanese encephalitis virus NS5 through a protein tyrosine phosphatase-mediated mechanism
-
Lin R.J., Chang B.L., Yu H.P., Liao C.L., and Lin Y.L. Blocking of IFN-induced Jak-Stat signaling by Japanese encephalitis virus NS5 through a protein tyrosine phosphatase-mediated mechanism. J. Virol. 80 (2006) 5908-5918
-
(2006)
J. Virol.
, vol.80
, pp. 5908-5918
-
-
Lin, R.J.1
Chang, B.L.2
Yu, H.P.3
Liao, C.L.4
Lin, Y.L.5
-
11
-
-
4143151721
-
Blocking of the alpha IFN-induced Jak-Stat signaling pathway by Japanese encephalitis virus infection
-
Lin R.J., Liao C.L., Lin E., and Lin Y.L. Blocking of the alpha IFN-induced Jak-Stat signaling pathway by Japanese encephalitis virus infection. J. Virol. 78 (2004) 9285-9294
-
(2004)
J. Virol.
, vol.78
, pp. 9285-9294
-
-
Lin, R.J.1
Liao, C.L.2
Lin, E.3
Lin, Y.L.4
-
12
-
-
34249077040
-
Functional determinants of NS2B for activation of Japanese encephalitis virus NS3 protease
-
Lin C.W., Huang H.D., Shiu S.Y., Chen W.J., Tsai M.H., Huang S.H., Wan L., and Lin Y.J. Functional determinants of NS2B for activation of Japanese encephalitis virus NS3 protease. Virus Res. 127 (2007) 88-94
-
(2007)
Virus Res.
, vol.127
, pp. 88-94
-
-
Lin, C.W.1
Huang, H.D.2
Shiu, S.Y.3
Chen, W.J.4
Tsai, M.H.5
Huang, S.H.6
Wan, L.7
Lin, Y.J.8
-
13
-
-
32344434707
-
Japanese encephalitis virus NS2B-NS3 protease binding to phage-displayed human brain proteins with the domain of trypsin inhibitor and basic region leucine zipper
-
Lin C.W., Lin K.H., Lyu P.C., and Chen W.J. Japanese encephalitis virus NS2B-NS3 protease binding to phage-displayed human brain proteins with the domain of trypsin inhibitor and basic region leucine zipper. Virus Res. 116 (2006) 106-113
-
(2006)
Virus Res.
, vol.116
, pp. 106-113
-
-
Lin, C.W.1
Lin, K.H.2
Lyu, P.C.3
Chen, W.J.4
-
14
-
-
27544476966
-
Binding interaction of SARS coronavirus 3CL(pro) protease with vacuolar-H+ATPase G1 subunit
-
Lin C.W., Tsai F.J., Wan L., Lai C.C., Lin K.H., Hsieh T.H., Shiu S.Y., and Li J.Y. Binding interaction of SARS coronavirus 3CL(pro) protease with vacuolar-H+ATPase G1 subunit. FEBS Lett. 579 (2005) 6089-6094
-
(2005)
FEBS Lett.
, vol.579
, pp. 6089-6094
-
-
Lin, C.W.1
Tsai, F.J.2
Wan, L.3
Lai, C.C.4
Lin, K.H.5
Hsieh, T.H.6
Shiu, S.Y.7
Li, J.Y.8
-
15
-
-
0000163169
-
Flaviviridae: the viruses and their replication
-
Knipe D.M., and Howley P.M. (Eds), Lippincott-Williams and Wilkins, New York
-
Lindenbach B.D.M., and Rice C. Flaviviridae: the viruses and their replication. In: Knipe D.M., and Howley P.M. (Eds). Fields Virology. 4th ed. (2001), Lippincott-Williams and Wilkins, New York 991-1041
-
(2001)
Fields Virology. 4th ed.
, pp. 991-1041
-
-
Lindenbach, B.D.M.1
Rice, C.2
-
16
-
-
13744254078
-
Inhibition of IFN signaling by the New York 99 strain and Kunjin subtype of West Nile virus involves blockage of STAT1 and STAT2 activation by nonstructural proteins
-
Liu W.J., Wang X.J., Mokhonov V.V., Shi P.Y., Randall R., and Khromykh A.A. Inhibition of IFN signaling by the New York 99 strain and Kunjin subtype of West Nile virus involves blockage of STAT1 and STAT2 activation by nonstructural proteins. J. Virol. 79 (2005) 1934-1942
-
(2005)
J. Virol.
, vol.79
, pp. 1934-1942
-
-
Liu, W.J.1
Wang, X.J.2
Mokhonov, V.V.3
Shi, P.Y.4
Randall, R.5
Khromykh, A.A.6
-
17
-
-
33144482922
-
A single amino acid substitution in the West Nile virus nonstructural protein NS2A disables its ability to inhibit alpha/beta IFN induction and attenuates virus virulence in mice
-
Liu W.J., Wang X.J., Clark D.C., Lobigs M., Hall R.A., and Khromykh A.A. A single amino acid substitution in the West Nile virus nonstructural protein NS2A disables its ability to inhibit alpha/beta IFN induction and attenuates virus virulence in mice. J. Virol. 80 (2006) 2396-2404
-
(2006)
J. Virol.
, vol.80
, pp. 2396-2404
-
-
Liu, W.J.1
Wang, X.J.2
Clark, D.C.3
Lobigs, M.4
Hall, R.A.5
Khromykh, A.A.6
-
18
-
-
33846061693
-
Inhibition of retinoic acid-inducible gene I-mediated induction of beta IFN by the NS1 protein of influenza A virus
-
Mibayashi M., Martínez-Sobrido L., Loo Y.M., Cárdenas W.B., Gale Jr. M., and García-Sastre A. Inhibition of retinoic acid-inducible gene I-mediated induction of beta IFN by the NS1 protein of influenza A virus. J. Virol. 81 (2007) 514-524
-
(2007)
J. Virol.
, vol.81
, pp. 514-524
-
-
Mibayashi, M.1
Martínez-Sobrido, L.2
Loo, Y.M.3
Cárdenas, W.B.4
Gale Jr., M.5
García-Sastre, A.6
-
19
-
-
34247848008
-
The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner
-
Miller S., Kastner S., Krijnse-Locker J., Bühler S., and Bartenschlager R. The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner. J. Biol. Chem. 282 (2007) 8873-8882
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 8873-8882
-
-
Miller, S.1
Kastner, S.2
Krijnse-Locker, J.3
Bühler, S.4
Bartenschlager, R.5
-
21
-
-
20744453948
-
Inhibition of alpha/beta IFN signaling by the NS4B protein of flaviviruses
-
Munoz-Jordan J.L., Laurent-Rolle M., Ashour J., Martínez-Sobrido L., Ashok M., Lipkin W.I., and Garcia-Sastre A. Inhibition of alpha/beta IFN signaling by the NS4B protein of flaviviruses. J. Virol. 79 (2005) 8004-8013
-
(2005)
J. Virol.
, vol.79
, pp. 8004-8013
-
-
Munoz-Jordan, J.L.1
Laurent-Rolle, M.2
Ashour, J.3
Martínez-Sobrido, L.4
Ashok, M.5
Lipkin, W.I.6
Garcia-Sastre, A.7
-
22
-
-
34250827756
-
Identification of residues critical for the IFN antagonist function of Langat Virus NS5 reveals a role for the RNA-dependent RNA polymerase domain
-
Park G.S., Morris K.L., Hallett R.G., Bloom M.E., and Best S.M. Identification of residues critical for the IFN antagonist function of Langat Virus NS5 reveals a role for the RNA-dependent RNA polymerase domain. J. Virol. 81 (2007) 6936-6946
-
(2007)
J. Virol.
, vol.81
, pp. 6936-6946
-
-
Park, G.S.1
Morris, K.L.2
Hallett, R.G.3
Bloom, M.E.4
Best, S.M.5
-
23
-
-
33750984771
-
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates
-
Pichlmair A., Schulz O., Tan C.P., Näslund T.I., Liljeström P., Weber F., and Reis e Sousa C. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates. Science 314 (2006) 997-1001
-
(2006)
Science
, vol.314
, pp. 997-1001
-
-
Pichlmair, A.1
Schulz, O.2
Tan, C.P.3
Näslund, T.I.4
Liljeström, P.5
Weber, F.6
Reis e Sousa, C.7
-
24
-
-
33646167045
-
Regulated cleavages at the West Nile virus NS4A-2K-NS4B junctions play a major role in rearranging cytoplasmic membranes and Golgi trafficking of the NS4A protein
-
Roosendaal J., Westaway E.G., Khromykh A., and Mackenzie J.M. Regulated cleavages at the West Nile virus NS4A-2K-NS4B junctions play a major role in rearranging cytoplasmic membranes and Golgi trafficking of the NS4A protein. J. Virol. 8 (2006) 4623-4632
-
(2006)
J. Virol.
, vol.8
, pp. 4623-4632
-
-
Roosendaal, J.1
Westaway, E.G.2
Khromykh, A.3
Mackenzie, J.M.4
-
25
-
-
27144486896
-
Alpha/beta IFN protects against lethal West Nile virus infection by restricting cellular tropism and enhancing neuronal survival
-
Samuel M.A., and Diamond M.S. Alpha/beta IFN protects against lethal West Nile virus infection by restricting cellular tropism and enhancing neuronal survival. J. Virol. 79 (2005) 13350-13361
-
(2005)
J. Virol.
, vol.79
, pp. 13350-13361
-
-
Samuel, M.A.1
Diamond, M.S.2
-
26
-
-
35448937696
-
Differential expression of IFN (IFN) regulatory factors and IFN-stimulated genes at early times after West Nile virus infection of mouse embryo fibroblasts
-
Scherbik S.V., Stockman B.M., and Brinton M.A. Differential expression of IFN (IFN) regulatory factors and IFN-stimulated genes at early times after West Nile virus infection of mouse embryo fibroblasts. J. Virol. 81 (2007) 12005-12018
-
(2007)
J. Virol.
, vol.81
, pp. 12005-12018
-
-
Scherbik, S.V.1
Stockman, B.M.2
Brinton, M.A.3
-
27
-
-
0034013015
-
Japanese encephalitis
-
Solomon T., Dung N.M., Kneen R., Gainsborough M., Vaughn D.W., and Khanh V.T. Japanese encephalitis. J. Neurol. Neurosurg. Psychiatry 68 (2000) 405-415
-
(2000)
J. Neurol. Neurosurg. Psychiatry
, vol.68
, pp. 405-415
-
-
Solomon, T.1
Dung, N.M.2
Kneen, R.3
Gainsborough, M.4
Vaughn, D.W.5
Khanh, V.T.6
-
28
-
-
0037426083
-
IFN alfa-2a in Japanese encephalitis: a randomised double-blind placebo-controlled trial
-
Solomon T., Dung N.M., Wills B., Kneen R., Gainsborough M., Diet T.V., Thuy T.T., Loan H.T., Khanh V.C., Vaughn D.W., White N.J., and Farrar J.J. IFN alfa-2a in Japanese encephalitis: a randomised double-blind placebo-controlled trial. Lancet 361 (2003) 821-826
-
(2003)
Lancet
, vol.361
, pp. 821-826
-
-
Solomon, T.1
Dung, N.M.2
Wills, B.3
Kneen, R.4
Gainsborough, M.5
Diet, T.V.6
Thuy, T.T.7
Loan, H.T.8
Khanh, V.C.9
Vaughn, D.W.10
White, N.J.11
Farrar, J.J.12
-
29
-
-
31644440766
-
Ddx42p-a human DEAD box protein with RNA chaperone activities
-
Uhlmann-Schiffler H., Jalal C., and Stahl H. Ddx42p-a human DEAD box protein with RNA chaperone activities. Nucleic Acids Res. 34 (2006) 10-22
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 10-22
-
-
Uhlmann-Schiffler, H.1
Jalal, C.2
Stahl, H.3
-
30
-
-
0032477720
-
The polyoma virus T antigen interferes with IFN-inducible gene expression
-
Weihua X., Ramanujam S., Lindner D.J., Kudaravalli R.D., Freund R., and Kalvakolanu D.V. The polyoma virus T antigen interferes with IFN-inducible gene expression. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 1085-1090
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 1085-1090
-
-
Weihua, X.1
Ramanujam, S.2
Lindner, D.J.3
Kudaravalli, R.D.4
Freund, R.5
Kalvakolanu, D.V.6
-
31
-
-
23844438864
-
Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity
-
Yoneyama M., Kikuchi M., Matsumoto K., Imaizumi T., Miyagishi M., Taira K., Foy E., Loo Y.M., Gale Jr. M., Akira S., Yonehara S., Kato A., and Fujita T. Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J. Immunol. 175 (2005) 2851-2858
-
(2005)
J. Immunol.
, vol.175
, pp. 2851-2858
-
-
Yoneyama, M.1
Kikuchi, M.2
Matsumoto, K.3
Imaizumi, T.4
Miyagishi, M.5
Taira, K.6
Foy, E.7
Loo, Y.M.8
Gale Jr., M.9
Akira, S.10
Yonehara, S.11
Kato, A.12
Fujita, T.13
|