-
1
-
-
33744513103
-
Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain
-
Amphoux A., Vialou V., Drescher E., Bruss M., Mannoury La Cour C., Rochat C., Millan M.J., Giros B., Bonisch H., and Gautron S. Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain. Neuropharmacology 50 (2006) 941-952
-
(2006)
Neuropharmacology
, vol.50
, pp. 941-952
-
-
Amphoux, A.1
Vialou, V.2
Drescher, E.3
Bruss, M.4
Mannoury La Cour, C.5
Rochat, C.6
Millan, M.J.7
Giros, B.8
Bonisch, H.9
Gautron, S.10
-
2
-
-
0025311288
-
Epithelial transport of drugs in cell culture. I: A model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cells
-
Artursson P. Epithelial transport of drugs in cell culture. I: A model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cells. J. Pharm. Sci. 79 (1990) 476-482
-
(1990)
J. Pharm. Sci.
, vol.79
, pp. 476-482
-
-
Artursson, P.1
-
3
-
-
0030588644
-
The use of the intestinal epithelial cell culture model, Caco-2, in pharmaceutical development
-
Bailey C., Bryla P., and Malick A. The use of the intestinal epithelial cell culture model, Caco-2, in pharmaceutical development. Adv. Drug Deliv. Rev. 22 (1996) 85-103
-
(1996)
Adv. Drug Deliv. Rev.
, vol.22
, pp. 85-103
-
-
Bailey, C.1
Bryla, P.2
Malick, A.3
-
4
-
-
33746427894
-
Apparent active transport of MDMA is not mediated by P-glycoprotein: a comparison with MDCK and Caco-2 monolayers
-
Bertelsen K.M., Greenblatt D.J., and von Moltke L.L. Apparent active transport of MDMA is not mediated by P-glycoprotein: a comparison with MDCK and Caco-2 monolayers. Biopharm. Drug Dispos. 27 (2006) 219-227
-
(2006)
Biopharm. Drug Dispos.
, vol.27
, pp. 219-227
-
-
Bertelsen, K.M.1
Greenblatt, D.J.2
von Moltke, L.L.3
-
5
-
-
0035868827
-
Measurement of secretory vesicle pH reveals intravesicular alkalinization by vesicular monoamine transporter type 2 resulting in inhibition of prohormone cleavage
-
Blackmore C.G., Varro A., Dimaline R., Bishop L., Gallacher D.V., and Dockray G.J. Measurement of secretory vesicle pH reveals intravesicular alkalinization by vesicular monoamine transporter type 2 resulting in inhibition of prohormone cleavage. J. Physiol. 531 (2001) 605-617
-
(2001)
J. Physiol.
, vol.531
, pp. 605-617
-
-
Blackmore, C.G.1
Varro, A.2
Dimaline, R.3
Bishop, L.4
Gallacher, D.V.5
Dockray, G.J.6
-
7
-
-
33749533053
-
Role of P glycoprotein in absorption of novel antimalarial drugs
-
Crowe A., Ilett K.F., Karunajeewa H.A., Batty K.T., and Davis T.M. Role of P glycoprotein in absorption of novel antimalarial drugs. Antimicrob. Agents Chemother. 50 (2006) 3504-3506
-
(2006)
Antimicrob. Agents Chemother.
, vol.50
, pp. 3504-3506
-
-
Crowe, A.1
Ilett, K.F.2
Karunajeewa, H.A.3
Batty, K.T.4
Davis, T.M.5
-
8
-
-
0031786057
-
In vitro and in situ absorption of SDZ-RAD using a human intestinal cell line (Caco-2) and a single pass perfusion model in rats: comparison with rapamycin
-
Crowe A., and Lemaire M. In vitro and in situ absorption of SDZ-RAD using a human intestinal cell line (Caco-2) and a single pass perfusion model in rats: comparison with rapamycin. Pharm. Res. 15 (1998) 1666-1672
-
(1998)
Pharm. Res.
, vol.15
, pp. 1666-1672
-
-
Crowe, A.1
Lemaire, M.2
-
9
-
-
33746824653
-
Limited P-glycoprotein mediated efflux for anti-epileptic drugs
-
Crowe A., and Teoh Y.K. Limited P-glycoprotein mediated efflux for anti-epileptic drugs. J. Drug Target. 14 (2006) 291-300
-
(2006)
J. Drug Target.
, vol.14
, pp. 291-300
-
-
Crowe, A.1
Teoh, Y.K.2
-
10
-
-
3042588695
-
pH dependent uptake of loperamide across the gastrointestinal tract: an in vitro study
-
Crowe A., and Wong P. pH dependent uptake of loperamide across the gastrointestinal tract: an in vitro study. Drug Dev. Ind. Pharm. 30 (2004) 449-459
-
(2004)
Drug Dev. Ind. Pharm.
, vol.30
, pp. 449-459
-
-
Crowe, A.1
Wong, P.2
-
12
-
-
0029818984
-
The role of extraneuronal amine transport systems for the removal of extracellular catecholamines in the rabbit
-
Friedgen B., Wolfel R., Russ H., Schomig E., and Graefe K.H. The role of extraneuronal amine transport systems for the removal of extracellular catecholamines in the rabbit. Naunyn-Schmiedeberg's Arch. Pharmacol. 354 (1996) 275-286
-
(1996)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.354
, pp. 275-286
-
-
Friedgen, B.1
Wolfel, R.2
Russ, H.3
Schomig, E.4
Graefe, K.H.5
-
13
-
-
0031022120
-
Application of the Caco-2 model in the design and development of orally active drugs: elucidation of biochemical and physical barriers posed by the intestinal epithelium
-
Gan L., and Thakker D. Application of the Caco-2 model in the design and development of orally active drugs: elucidation of biochemical and physical barriers posed by the intestinal epithelium. Adv. Drug Deliv. Rev. 23 (1997) 77-98
-
(1997)
Adv. Drug Deliv. Rev.
, vol.23
, pp. 77-98
-
-
Gan, L.1
Thakker, D.2
-
14
-
-
0022067913
-
Epithelial properties of human colonic carcinoma cell line Caco-2: effects of secretagogues
-
Grasset E., Bernabeu J., and Pinto M. Epithelial properties of human colonic carcinoma cell line Caco-2: effects of secretagogues. Am. J. Physiol. 248 (1985) C410-C418
-
(1985)
Am. J. Physiol.
, vol.248
-
-
Grasset, E.1
Bernabeu, J.2
Pinto, M.3
-
15
-
-
33646073783
-
Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs
-
Han D.D., and Gu H.H. Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs. BMC Pharmacol. 6 (2006) 6
-
(2006)
BMC Pharmacol.
, vol.6
, pp. 6
-
-
Han, D.D.1
Gu, H.H.2
-
16
-
-
0024593744
-
Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability
-
Hidalgo I., Raub T., and Borchardt R. Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability. Gastroenterology 96 (1989) 736-749
-
(1989)
Gastroenterology
, vol.96
, pp. 736-749
-
-
Hidalgo, I.1
Raub, T.2
Borchardt, R.3
-
17
-
-
0029896241
-
Age-dependent expression of P-glycoprotein gp170 in Caco-2 cell monolayers
-
Hosoya K., Kim K., and Lee V. Age-dependent expression of P-glycoprotein gp170 in Caco-2 cell monolayers. Pharm. Res. 13 (1996) 885-890
-
(1996)
Pharm. Res.
, vol.13
, pp. 885-890
-
-
Hosoya, K.1
Kim, K.2
Lee, V.3
-
18
-
-
0027369881
-
Pharmacokinetics of oral decongestants
-
discussion 143S-146S
-
Kanfer I., Dowse R., and Vuma V. Pharmacokinetics of oral decongestants. Pharmacotherapy 13 (1993) 116S-128S discussion 143S-146S
-
(1993)
Pharmacotherapy
, vol.13
-
-
Kanfer, I.1
Dowse, R.2
Vuma, V.3
-
19
-
-
0347762493
-
P-glycoprotein modulation by the designer drugs methylenedioxymethamphetamine, methylenedioxyethylamphetamine and paramethoxyamphetamine
-
Ketabi-Kiyanvash N., Weiss J., Haefeli W.E., and Mikus G. P-glycoprotein modulation by the designer drugs methylenedioxymethamphetamine, methylenedioxyethylamphetamine and paramethoxyamphetamine. Addict. Biol. 8 (2003) 413-418
-
(2003)
Addict. Biol.
, vol.8
, pp. 413-418
-
-
Ketabi-Kiyanvash, N.1
Weiss, J.2
Haefeli, W.E.3
Mikus, G.4
-
20
-
-
38149118966
-
Uptake of 3,4-methylenedioxymethamphetamine and its related compounds by a proton-coupled transport system in Caco-2 cells
-
Kuwayama K., Inoue H., Kanamori T., Tsujikawa K., Miyaguchi H., Iwata Y., Miyauchi S., Kamo N., and Kishi T. Uptake of 3,4-methylenedioxymethamphetamine and its related compounds by a proton-coupled transport system in Caco-2 cells. Biochim. Biophys. Acta 1778 (2008) 42-50
-
(2008)
Biochim. Biophys. Acta
, vol.1778
, pp. 42-50
-
-
Kuwayama, K.1
Inoue, H.2
Kanamori, T.3
Tsujikawa, K.4
Miyaguchi, H.5
Iwata, Y.6
Miyauchi, S.7
Kamo, N.8
Kishi, T.9
-
21
-
-
0030832634
-
Differential toxic effects of methamphetamine (METH) and methylenedioxymethamphetamine (MDMA) in multidrug-resistant (mdr1a) knockout mice
-
Mann H., Ladenheim B., Hirata H., Moran T., and Cadet J. Differential toxic effects of methamphetamine (METH) and methylenedioxymethamphetamine (MDMA) in multidrug-resistant (mdr1a) knockout mice. Brain Res. 769 (1997) 340-346
-
(1997)
Brain Res.
, vol.769
, pp. 340-346
-
-
Mann, H.1
Ladenheim, B.2
Hirata, H.3
Moran, T.4
Cadet, J.5
-
22
-
-
27144527244
-
Modulation of MPP+ uptake by tea and some of its components in Caco-2 cells
-
Monteiro R., Calhau C., Martel F., Faria A., Mateus N., and Azevedo I. Modulation of MPP+ uptake by tea and some of its components in Caco-2 cells. Naunyn-Schmiedeberg's Arch. Pharmacol. 372 (2005) 147-152
-
(2005)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.372
, pp. 147-152
-
-
Monteiro, R.1
Calhau, C.2
Martel, F.3
Faria, A.4
Mateus, N.5
Azevedo, I.6
-
23
-
-
33749017668
-
Interaction of amphetamines and related compounds at the vesicular monoamine transporter
-
Partilla J.S., Dempsey A.G., Nagpal A.S., Blough B.E., Baumann M.H., and Rothman R.B. Interaction of amphetamines and related compounds at the vesicular monoamine transporter. J. Pharmacol. Exp. Ther. 319 (2006) 237-246
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.319
, pp. 237-246
-
-
Partilla, J.S.1
Dempsey, A.G.2
Nagpal, A.S.3
Blough, B.E.4
Baumann, M.H.5
Rothman, R.B.6
-
24
-
-
34249989197
-
Extraneuronal monoamine transporter and organic cation transporters 1 and 2: a review of transport efficiency
-
Schomig E., Lazar A., and Grundemann D. Extraneuronal monoamine transporter and organic cation transporters 1 and 2: a review of transport efficiency. Handb. Exp. Pharmacol. (2006) 151-180
-
(2006)
Handb. Exp. Pharmacol.
, pp. 151-180
-
-
Schomig, E.1
Lazar, A.2
Grundemann, D.3
-
25
-
-
0020608563
-
Mechanism of uptake and retrograde axonal transport of noradrenaline in sympathetic neurons in culture: reserpine-resistant large dense-core vesicles as transport vehicles
-
Schwab M.E., and Thoenen H. Mechanism of uptake and retrograde axonal transport of noradrenaline in sympathetic neurons in culture: reserpine-resistant large dense-core vesicles as transport vehicles. J. Cell Biol. 96 (1983) 1538-1547
-
(1983)
J. Cell Biol.
, vol.96
, pp. 1538-1547
-
-
Schwab, M.E.1
Thoenen, H.2
-
26
-
-
33747090656
-
Variability in mRNA expression of ABC- and SLC-transporters in human intestinal cells: comparison between human segments and Caco-2 cells
-
Seithel A., Karlsson J., Hilgendorf C., Bjorquist A., and Ungell A.L. Variability in mRNA expression of ABC- and SLC-transporters in human intestinal cells: comparison between human segments and Caco-2 cells. Eur. J. Pharm. Sci. 28 (2006) 291-299
-
(2006)
Eur. J. Pharm. Sci.
, vol.28
, pp. 291-299
-
-
Seithel, A.1
Karlsson, J.2
Hilgendorf, C.3
Bjorquist, A.4
Ungell, A.L.5
-
27
-
-
0025938139
-
Facilitating effect of amphetamine on the response of rabbit aortic strips to adrenaline, dopamine and serotonin
-
Silvestrini B., Palmery M., Basta F., and Valeri P. Facilitating effect of amphetamine on the response of rabbit aortic strips to adrenaline, dopamine and serotonin. J. Neural.Transm. Gen. sect. 86 (1991) 51-59
-
(1991)
J. Neural.Transm. Gen. sect.
, vol.86
, pp. 51-59
-
-
Silvestrini, B.1
Palmery, M.2
Basta, F.3
Valeri, P.4
-
28
-
-
1842503142
-
Simultaneous determination of amphetamine derivatives in human urine after SPE extraction and HPLC-UV analysis
-
Soares M., Carvalho M., Remiao F., and Bastos M. Simultaneous determination of amphetamine derivatives in human urine after SPE extraction and HPLC-UV analysis. Biomed. Chromatogr. 18 (2004) 125-131
-
(2004)
Biomed. Chromatogr.
, vol.18
, pp. 125-131
-
-
Soares, M.1
Carvalho, M.2
Remiao, F.3
Bastos, M.4
-
29
-
-
0025647857
-
Amphetamine and other psychostimulants reduce pH gradients in midbrain dopaminergic neurons and chromaffin granules: a mechanism of action
-
Sulzer D., and Rayport S. Amphetamine and other psychostimulants reduce pH gradients in midbrain dopaminergic neurons and chromaffin granules: a mechanism of action. Neuron 5 (1990) 797-808
-
(1990)
Neuron
, vol.5
, pp. 797-808
-
-
Sulzer, D.1
Rayport, S.2
-
30
-
-
0018651761
-
Renal excretion of pseudoephedrine in the rat
-
Till A.E., and Benet L.Z. Renal excretion of pseudoephedrine in the rat. J. Pharmacol. Exp. Ther. 211 (1979) 555-560
-
(1979)
J. Pharmacol. Exp. Ther.
, vol.211
, pp. 555-560
-
-
Till, A.E.1
Benet, L.Z.2
-
31
-
-
0029782485
-
Carrier-mediated intestinal transport of drugs
-
Tsuji A., and Tamai I. Carrier-mediated intestinal transport of drugs. Pharm. Res. 13 (1996) 963-977
-
(1996)
Pharm. Res.
, vol.13
, pp. 963-977
-
-
Tsuji, A.1
Tamai, I.2
-
32
-
-
43249126070
-
Fluoxetine pretreatment effects pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA, ECSTASY) in rat
-
Upreti V.V., and Eddington N.D. Fluoxetine pretreatment effects pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA, ECSTASY) in rat. J. Pharm. Sci. 97 (2008) 1593-1605
-
(2008)
J. Pharm. Sci.
, vol.97
, pp. 1593-1605
-
-
Upreti, V.V.1
Eddington, N.D.2
-
33
-
-
0030588923
-
Determination of amphetamine in human urine by dansyl derivatization and high-performance liquid chromatography with fluorescence detection
-
Wang T.K., and Fuh M.S. Determination of amphetamine in human urine by dansyl derivatization and high-performance liquid chromatography with fluorescence detection. J. Chromatogr., B Biomed. Appl. 686 (1996) 285-290
-
(1996)
J. Chromatogr., B Biomed. Appl.
, vol.686
, pp. 285-290
-
-
Wang, T.K.1
Fuh, M.S.2
-
34
-
-
0034059327
-
Atorvastatin transport in the Caco-2 cell model: contribution of P-glycoprotein and the proton-monocarboxylic acid co-transporter
-
Wu X., Whitfield L., and Stewart B. Atorvastatin transport in the Caco-2 cell model: contribution of P-glycoprotein and the proton-monocarboxylic acid co-transporter. Pharm. Res. 17 (2000) 209-215
-
(2000)
Pharm. Res.
, vol.17
, pp. 209-215
-
-
Wu, X.1
Whitfield, L.2
Stewart, B.3
-
35
-
-
0036141727
-
Dansyl chloride derivatization of methamphetamine: a method with advantages for screening and analysis of methamphetamine in urine
-
Yamada H., Yamahara A., Yasuda S., Abe M., Oguri K., Fukushima S., and Ikeda-Wada S. Dansyl chloride derivatization of methamphetamine: a method with advantages for screening and analysis of methamphetamine in urine. J. Anal. Toxicol. 26 (2002) 17-22
-
(2002)
J. Anal. Toxicol.
, vol.26
, pp. 17-22
-
-
Yamada, H.1
Yamahara, A.2
Yasuda, S.3
Abe, M.4
Oguri, K.5
Fukushima, S.6
Ikeda-Wada, S.7
-
36
-
-
0037382257
-
Interaction between flavonoids and the blood-brain barrier: in vitro studies
-
Youdim K., Dobbie M., Kulhnle G., Proteggente A., Abbott N., and Rice-Evans C. Interaction between flavonoids and the blood-brain barrier: in vitro studies. J. Neurochem. 85 (2003) 180-192
-
(2003)
J. Neurochem.
, vol.85
, pp. 180-192
-
-
Youdim, K.1
Dobbie, M.2
Kulhnle, G.3
Proteggente, A.4
Abbott, N.5
Rice-Evans, C.6
-
37
-
-
33745271384
-
The role of the polymorphic efflux transporter P-glycoprotein on the brain accumulation of d-methylphenidate and d-amphetamine
-
Zhu H.J., Wang J.S., DeVane C.L., Williard R.L., Donovan J.L., Middaugh L.D., Gibson B.B., Patrick K.S., and Markowitz J.S. The role of the polymorphic efflux transporter P-glycoprotein on the brain accumulation of d-methylphenidate and d-amphetamine. Drug Metab. Dispos. 34 (2006) 1116-1121
-
(2006)
Drug Metab. Dispos.
, vol.34
, pp. 1116-1121
-
-
Zhu, H.J.1
Wang, J.S.2
DeVane, C.L.3
Williard, R.L.4
Donovan, J.L.5
Middaugh, L.D.6
Gibson, B.B.7
Patrick, K.S.8
Markowitz, J.S.9
|