The role of extraneuronal amine transport systems for the removal of extracellular catecholamines in the rabbit

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 354, Issue 3, 1996, Pages 275-286

  Friedgen, Bernd ^a   Wölfel, Reinhard ^a   Russ, Hermann ^b   Schömig, Edgar ^c   Graefe, Karl Heinz ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

COMT inhibition; Disprocynium24; MAO inhibition; Organic cation transporters; Plasma clearance of catecholamines; Uptake2

Indexed keywords

1,1' DIISOPROPYL 2,4' CYANINE; ADRENALIN; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; AMINE OXIDASE (FLAVIN CONTAINING); CATECHOL METHYLTRANSFERASE; CATECHOLAMINE DERIVATIVE; DISPROCYNIUM 24; DOPAMINE; NORADRENALIN; UNCLASSIFIED DRUG;

ADRENALIN RELEASE; AMINE TRANSPORT; ANIMAL EXPERIMENT; ARTICLE; CATECHOLAMINERGIC SYSTEM; CONTROLLED STUDY; DOPAMINE RELEASE; INTRAVENOUS DRUG ADMINISTRATION; MONOAMINERGIC SYSTEM; NONHUMAN; NORADRENALIN RELEASE; RABBIT;

EID: 0029818984     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00171058     Document Type: Article

References (49)

1. Bryan-Lluka LJ, O'Donnell SR (1992) Dopamine and adrenaline, but not isoprenaline, are substrates for uptake and metabolism in isolated perfused lungs of rats. Naunyn-Schmiedeberg's Arch Pharmacol 346:20-26
2. 1 in noradrenergic neurones. Naunyn-Schmiedeberg's Arch Pharmacol 345:319-326
3. Cohen MD, Finberg J, Dibner-Dunlap M, Yuish SN, Thames MD (1990) Effects of desipramine hydrochloride on peripheral sympathetic nerve activity. Am J Physiol 258 (Regulatory Integrative Comp Physiol 27): R876-R882
4. Cuche J-L, Brochier P, Klioua N, Poirier M-F, Cuche H, Benmiloud M, Loo H, Safar M (1990) Conjugated catecholamines in human plasma: Where are they coming from? J Lab Clin Med 116: 681-686
5. Eisenhofer G, Goldstein DS, Kopin IJ (1989) Plasma dihydroxyphenylglycol for estimation of noradrenaline neuronal re-uptake in the sympathetic nervous system in vivo. Clin Sci 76: 171-182
6. Eisenhofer G, Esler MD, Meredith IT, Ferrier C, Lambert G, Jennings G (1991a) Neuronal re-uptake of noradrenaline by sympathetic nerves in humans. Clin Sci 80: 257-263
7. Eisenhofer G, Saigusa T, Esler, MD, Cox HS, Angus JA, Dorward PK (1991b) Central sympathoinhibition and peripheral neuronal uptake blockade after desipramine in rabbits. Am J Physiol 260 (Regulatory Integrative Comp Physiol 29): R824-R832
8. Eisenhofer G, Åneman A, Hooper D, Holmes C, Goldstein DS, Friberg P (1995) Production and metabolism of dopamine and noradrenaline in mesenteric organs and liver of swine. Am J Physiol 268 (Gastrointest Liver Physiol 31): G641-G649
9. Eisenhofer G, McCarty R, Pacak K, Russ H, Schomig H (1996) Disprocynium24, a novel inhibitor of the extraneuronal monoamine transporter, has potent effects on the inactivation of circulating norepinephrine and epinephrine in conscious rats. Naunyn-Schmiedeberg's Arch Pharmacol 354:287-294
10. Esler M, Willett I, Leonard P, Hasking G, Johns J, Little P, Jennings G (1984) Plasma noradrenaline kinetics in humans. J Auton Nerv Syst 11:125-144
11. Friedgen B, Halbrügge T, Graefe K-H (1993) The part played by catechol-O-methyltransferase in the plasma kinetics of 3,4-dihydroxy-phenylglycol and 3,4-dihydroxyphenylalanine in the anaesthetized rabbit. Naunyn-Schmiedeberg's Arch Pharmacol 347: 155-161
12. 1 and catechol-O-methyltransferase in removal of circulating catecholamines in the rabbit. Am J Physiol 267 (Endocrinol Metab 30): E814-E821
13. 2) plays a role in vivo. Naunyn-Schmiedeberg's Arch Pharmacol 351 [Suppl]: R136
14. Friedgen B, Wölfel R, Graefe K-H (1996) The contribution by monoamine oxidase and catechol-O-methyltransferase to the total-body and pulmonary plasma clearance of catecholamines. Naunyn-Schmiedeberg's Arch Pharmacol 353:193-199
15. Fuentes JA, Ordaz A, Neff NH (1979) Central mediation of the anti-hypertensive effect of pargyline in spontaneously hypertensive rats. Eur J Pharmacol 57: 21-27
16. Gillespie JS (1976) Extraneuronal uptake of catecholamines in smooth muscle and connective tissue. In: Paton DM (ed) The mechanism of neuronal and extraneuronal transport of catecholamines. Raven Press, New York, pp 325-354
17. Goldstein DS, Zimlichman R, Stull R, Keiser HR, Kopin IJ (1986) Estimation of intrasynaptic noradrenaline concentrations in humans. Hypertension 8:471-475
18. Goldstein DS, Mezey E, Yamamoto T, Aneman A, Friberg P, Eisenhofer G (1995) Is there a third peripheral catecholaminergic system? Endogenous dopamine as an autocrine/paracrine substance derived from plasma DOPA and inactivated by conjugation. Hypertens Res 18 [Suppl I]:S93-S99
19. Graefe K-H, Bönisch H (1988) The transport of amines across the axonal membranes of noradrenergic and dopaminergic neurones. In: Trendelenburg U, Weiner N (eds) Catecholamines I. Handbook of Exp Pharmacol, vol 90/I. Springer, Berlin Heidelberg New York London Paris Tokyo, pp 193-245
20. Gründemann D, Gorboulev V, Gambaryan S, Veyhl M, Koepsell H (1994) Drug excretion mediated by a new prototype of polyspecific transporter. Nature 372: 549-552
21. Halbrügge T, Lütsch K, Thyen A, Graefe K-H (1991) Role of nitricoxide formation in the regulation of haemodynamics and the release of noradrenaline and adrenaline. Naunyn-Schmiedeberg's Arch Pharmacol 344: 720-727
22. Iversen LL (1965) The uptake of catecholamines at high perfusion concentrations in the rat isolated heart: a novel catechol amine uptake process. Br J Pharmacol 25:18-33
23. Iversen LL (1967) The uptake and storage of noradrenaline in sympathetic nerves. Cambridge University Press, Cambridge
24. Iversen LL (1975) Uptake processes for biogenic amines. In: Iversen LL, Iversen SH, Snyder SH (eds) Handbook of psychopharmacology, vol 3. Plenum Press, New York London, pp 381-442
25. 3H-(-)-noradrenaline by rabbit endometrium. Naunyn-Schmiedeberg's Arch Pharmacol 336:148-154
26. Kopin IJ, Zukowska-Grojec Z, Bayorh MA, Goldstein DS (1984) Estimation of intrasynaptic noradrenaline concentrations at vascular neuroeffector junctions in vivo. Naunyn-Schmiedeberg's Arch Pharmacol 325:298-305
27. Lappe RW, Henry DP, Willis LR (1980) Mechanism of renal tubular secretion of norepinephrine in the rabbit. J Pharmacol Exp Ther 215:443-449
28. Lingen B, Brüss M, Bönisch H (1994) Cloning and expression of the bovine sodium- and chloride-dependent noradrenaline transporter. FEBS Lett 342:235-238
29. Pacholczyk T, Blakely RD, Amara SG (1991) Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter. Nature 350:350-354
30. Parker DAS, de la Lande IS, Proctor C, Marino V, Lam NX, Parker I (1987) Cocaine-sensitive O-methylation of noradrenaline in dental pulp of the rabbit: comparison with the rabbit ear artery. Naunyn-Schmiedeberg's Arch Pharmacol 335:32-39
31. Pscheidt GR (1963) Anomalous actions of monoamine oxidase inhibitors. Ann NY Acad Sci 107:1057-1067
32. Rennick BR (1981) Renal tubular transport of organic cations. In: Greger R, Lang F, Silbernagl S (eds) Renal transport of organic substances. Springer, Berlin Heidelberg New York, pp 178-188
33. Russ H, Engel W, Schömig E (1993a) Isocyanines and pseudoisocyanines as a novel class of potent noradrenaline transport inhibitors: synthesis, detection, and biological activity. J Med Chem 36: 4208-4213
34. Russ H, Sonna J, Keppler K, Baunach S. Schömig E (1993b) Cyanine-related compounds: a novel class of potent inhibitors of extraneuronal noradrenaline transport. Naunyn-Schmiedeberg's Arch Pharmacol 348:458-465
35. 1-antagonistic properties of two cyanine-type inhibitors of extraneuronal monoamine transport. Naunyn-Schmiedeberg's Arch Pharmacol 354:268-274
36. 2 in the isolated rat heart by steroids, clonidine and methoxylated phenylethylamines. Eur J Pharmacol 20:329-340
37. 2) in a human cell line (Caki-1 cells). Naunyn-Schmiedeberg's Arch Pharmacol 341:404-410
38. Schömig E, Babin-Ebell J, Russ H (1993) 1,1′-Diethyl-2,2′-cyanine (decynium22) potently inhibits the renal transport of organic cations. Naunyn-Schmiedeberg's Arch Pharmacol 347:379-383
39. 293 cells. Naunyn-Schmiedeberg's Arch Pharmacol 351 [Suppl]: R88
40. 2) exists in the human central nervous system (CNS). Naunyn-Schmiedeberg's Arch Pharmacol 347 [Suppl]: R118
41. 2) in human glioma cells. Naunyn-Schmiedeberg's Arch Pharmacol 353:328-333
42. Szabo B, Schultheiss A (1990) Desipramine inhibits sympathetic nerve activity in the rabbit. Naunyn-Schmiedeberg's Arch Pharmacol 342:469-476
43. Szabo B, Schultheiss A, Starke K (1991) The noradrenaline uptake inhibitor, (+)-oxaprotiline, but not the inactive enantiomer, (-)-oxaprotiline, inhibits sympathetic nerve activity in the rabbit: involvement of adrenoceptors. Eur J Pharmacol 199:325-344
44. Trendelenburg U (1972) Factors influencing the concentration of catecholamines at the receptors. In: Blaschko H, Muscholl E (eds) Catecholamines. Handbook of Exp Pharmacol. vol 33. Springer, Berlin Heidelberg New York, pp 726-761
45. Trendelenburg U (1976) The extraneuronal uptake and metabolism of catecholamines in the heart. In: Paton DM (ed) The mechanism of neuronal and extraneuronal transport of catecholamines. Raven Press, New York, pp 259-280
46. Trendelenburg U (1980) A kinetic analysis of extraneuronal uptake and metabolism of catecholamines. Rev Physiol Biochem Pharmacol 87:33-115
47. Trendelenburg U (1988) The extraneuronal uptake and metabolism of catecholamines. In: Trendelenburg U, Weiner N (eds) Catecholamines I. Handbook of Exp Pharmacol, vol 90/I. Springer, Berlin Heidelberg New York London Paris Tokyo, pp 279-319
48. Vieira-Coelho MA, Soares-da-Silva P (1993) Dopamine formation, from its immediate precursor 3,4-dihydroxyphenylalanine, along the rat digestive tract. Fundam Clin Pharmacol 7:235-243
49. Youdim MBH, Finberg JPM, Tipton KF (1988) Monoamine oxidase. In: Trendelenburg U, Weiner N (eds) Catecholamines I. Handbook of Exp Pharmacol, vol 90/I. Springer, Berlin Heidelberg New York London Paris Tokyo, pp 119-192