Brain single-photon emission CT physics principles

American Journal of Neuroradiology

Volumn 29, Issue 7, 2008, Pages 1247-1256

  Accorsi, Roberto ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; 2 [[2 [(DIMETHYLAMINO)METHYL]THIO] 5 IODOPHENYL]AMINE IODINE 123; 2,3 DIHYDRO 1H IMIDAZO[1,2 B]PYRAZOLE; [2 [[2 [[[3 (4 CHLOROPHENYL) 8 METHYL 8 AZABICYCLO[3.2.1]OCT 2 YL]METHYL](2 MERCAPTOETHYL)AMINO]ETHYL]AMINO]ETHANETHIOLATO]OXOTECHNETIUM TC 99M; BETA CARBOMETHOXY 3 BETA (4 IODOPHENYL) TROPANE IODINE 123; CYSTEINE ETHYL ESTER TC 99M; GALLIUM EDETATE GA 67; HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; IODOBENZAMIDE I 123; IODOBENZOFURAN I 123; ISOPROPYLIODOAMPHETAMINE I 123; MEDRONATE TECHNETIUM TC 99M; OCTREOTIDE; PENTETATE INDIUM IN 111; PENTETREOTIDE IN 111; PYRIDINE DERIVATIVE; PYROPHOSPHATE TECHNETIUM TC 99M; TRACER; UNCLASSIFIED DRUG; XENON 133;

COLLIMATOR; COMPUTER ASSISTED TOMOGRAPHY; DRUG RETENTION; HALF LIFE TIME; HUMAN; MATHEMATICAL ANALYSIS; NEUROIMAGING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; QUANTITATIVE ANALYSIS; REVIEW; SCINTILLATION CAMERA; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ALGORITHMS; EQUIPMENT DESIGN; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; MATHEMATICS; NUCLEAR PHYSICS; POSITRON-EMISSION TOMOGRAPHY; RADIOISOTOPES; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOMOGRAPHY, X-RAY COMPUTED;

EID: 49749106643     PISSN: 01956108     EISSN: None     Source Type: Journal    
DOI: 10.3174/ajnr.A1175     Document Type: Review

References (121)

1. Donohoe KJ, Frey KA, Gerbaudo VH, et al. Procedure guideline for brain death scintigraphy. J Nucl Med 2003;44:846-51
2. Kuhl DE, Edwards RQ. Image separation radioisotope scanning. Radiology 1963;80:653-61
3. Jaszczak RJ. The early years of single photon emission tomography (SPECT): an anthology of selected reminiscences. Phys Med Biol 2006;51:R99-15
4. Kuhl DE, Edwards RQ. Cylindrical and section radioisotope scanning of the liver and the brain. Radiology 1964;83:926-35
5. Wagner HN, ed: Principles of Nuclear Medicine. Philadelphia: Saunders; 1995
6. Sandler MP, Coleman RE, Patton JA, et al. eds. Diagnostic Nuclear Medicine. 4th ed. Baltimore: Lippincott Williams & Wilkins; 2002
7. Cherry SR, Sorenson JA, Phelps ME. Physics in Nuclear Medicine. 3rd ed. Philadelphia: Saunders; 2003
8. Wernick MN, Aarsvold JN, eds. Emission Tomography: The Fundamentals of SPECT and PET. San Diego: Elsevier; 2004
9. Rosenthal MS, Cullom J, Hawkins W, et al. Quantitative SPECT imaging: a review and recommendations by the Focus Committee of the Society of Nuclear Medicine Computer and Instrumentation Council. J Nucl Med 1995;36:1489-513
10. Groch MW, Erwin WD. SPECT in the year 2000: basic principles. J Nucl Med Tech 2000;28:233-44
11. Madsen MT. Recent advances in SPECT imaging. J Nucl Med 2007;48:661-73
12. Moore SC, Kouris K, Cullum I. Collimator design for single photon emission tomography. Eur J Nucl Med 1992;19:138-50
13. Catafau AM. Brain SPECT in clinical practice. Part I. Perfusion. J Nucl Med 2001;42:259-71
14. Taber KH, Black KJ, Hurley RA. Blood flow imaging of the brain: 50 years experience. J Neuropsychiatry Clin Neurosci 2005;17:441-46
15. Camargo EE. Brain SPECT in neurology and psychiatry. J Nucl Med 2001;42:611-23
16. Heiss W-D, Herholz K. Brain receptor imaging. J Nucl Med 2006;47:302-12
17. Frankle WG, Slifstein M, Talbot PS, et al. Neuroreceptor imaging in psychiatry: theory and applications. Int Rev Neurobiol 2005;67:385-440
18. Biersack HJ, Klemm E, Menzel C, et al. Interventional brain SPECT: a review. Ann Nucl Med 1996;10:277-80
19. Juni JE, Waxman AD, Devous MD Sr, et al. Procedure guideline for brain perfusion SPECT using technetium-99m radiopharmaceuticals: Society of Nuclear Medicine. J Nucl Med 1998;39:923-26
20. Beer HF, Blauenstein PA, Hasler PH, et al. In vitro and in vivo evaluation of iodine-123-Ro 16-0154: a new imaging agent for SPECT investigations of benzodiazepine receptors. J Nucl Med 1990;31:1007-14
21. Oya S, Choi SR, Hou C, et al. 2-((2-((dimethylamino)methyl)phenyl) thio)-5-iodophenylamine (ADAM): an improved serotonin transporter ligand. Nucl Med Biol 2000;27:249-54
22. 125IJRT1-55: a potent ligand for dopamine transporters. Eur J Pharmacol 1991;194:133-34
23. Ichise M, Ballinger JR, Golan H, et al. Noninvasive quantification of dopamine D2 receptors with iodine-123-IBF SPECT. J Nucl Med 1996;37:513-20
24. Kung HF, Pan SG, Kung MP, et al. In vitro and in vivo evaluation of [I-123]IBZM: a potential CNS D2 dopamine receptor imaging agent. J Nucl Med 1989;30:88-92
25. Kung HF, Kasliwal R, Pan S, et al. Dopamine D2 receptor imaging radiopharmaceuticals: synthesis, radiolabeling and in vitro binding of R-(+)-and S-(-)-3-iodo-2-hydoxy-6-methoxy-N-[(l-ethyl-2-pyrrolidinyl)methyl] benzamide. J Med Chem 1988;31:1039-43
26. Kung HF, Kim HJ, Kung MP, et al. Imaging of dopamine transporters in humans with technetium-99m TRODAT-1. Eur J Nucl Med 1996;23:1527-30
27. Brown ML, Keyes JW Jr, Leonard PF, et al. Facial bone scanning by emission tomography. J Nucl Med 1977;18:1184-88
28. Krasnow AZ, Collier BD, Kneeland JB, et al. Comparison of high-resolution MRI and SPECT bone scintigraphy for noninvasive imaging of the temporo-mandibular joint. J Nucl Med 1987;28:1268-74
29. Ramsay SC, Yeates MG, Ho LCY. Bone scanning in the early assessment of nasal bone graft viability. J Nucl Med 1991;32:33-36
30. de Jong M, Bakker WH, Krenning EP, et al. Yttrium-90 and Indium-111 labelling, receptor binding and biodistribution of [DOTA0, d-Phe1,Tyr3] octreotide, a promising somatostatin analogue for radionuclide therapy. Eur J Nucl Med 1997;24:368-71
31. 111In-pentetreotide. J Nucl Med 2001;42:1134-38
32. Mukhin AG, Gundisch D, Horti AG, et al. 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors. Mol Pharmacol 2000;57:642-49
33. Kung MP, Hou C, Zhuang ZP, et al. IMPY: an improved thioflavin-T derivative for in vivo labeling of β-amyloid plaques. Brain Res 2002;956:202-10
34. Kung HF, Kung MP, Choi SR. Radiopharmaceuticals for single-photon emission computed tomography brain imaging. Semin Nucl Med 2003;33:2-13
35. Muehllehner G, Dudek J, Moyer R. Influence of hole shape on collimator performance. Phys Med Biol 1976;21:242-50
36. Metz CE, Atkins FB, Beck RN. The geometric transfer function component for scintillation camera collimators with straight parallel holes. Phys Med Biol 1980;25:1059-70
37. Jaszczak RJ, Chang LT, Murphy PH. Single photon emission computed tomography using multi-slice fan beam collimators. IEEE Trans Nuc Sci 1979;NS-26:610-18
38. Tsui BM, Gullberg GT, Edgerton ER, et al. Design and clinical utility of a fan beam collimator for SPECT imaging of the head. J Nucl Med 1986;27:810-19
39. Genna S, Pang SC, Burrows BA. Applications of fan reconstruction geometries to transmission and emission systems. In: Ter-Pogossian MM, ed. Reconstruction Tomography in Diagnostic Radiology and Nuclear Medicine. Baltimore: University Park Press; 1977:139-54
40. Jaszczak RJ, Floyd CE, Manglos SH, et al. Cone beam collimation for single photon emission computed tomography: analysis, simulation, and image reconstruction using filtered backprojection. Med Phys 1986;13:484-89
41. Jaszczak RJ, Greer KL, Coleman RE. SPECT using a specially designed cone-beam collimator. J Nucl Med 1988;29:1398-405
42. Li J, Jaszczak RJ, van Mullekom A, et al. Half-cone beam collimation for triple-camera SPECT systems. J Nucl Med 1996;37:498-502
43. Park MA, Moore SC, Kijewski MF. Brain SPECT with short focal-length cone-beam collimation. Med Phys 2005;32:2236-44
44. Hawman EG, Hsieh J. An astigmatic collimator for high-sensitivity SPECT of the brain. J Nucl Med 1986;27:930
45. Holmes RA, Logan KW, Hasselquist BE, et al. Clinical evaluation of an astigmatic collimator for high-sensitivity SPECT imaging of the brain. J Nucl Med 1987;28:576-77
46. Li J, Jaszczack RJ, Turkington TG, et al. An evaluation of lesion detectability with cone-beam, fanbeam, and parallel-beam collimation in SPECT by continuous ROC study. J Nucl Med 1994;35:135-40
47. Jaszczak RJ, Li J, Wang H, et al. Pinhole collimation for ultra-high-resolution, small-field-of-view SPECT. Phys Med Biol 1994;39:425-37
48. Weber DA, Ivanovic M, Franceschi D, et al. Pinhole SPECT: an approach to in vivo high-resolution SPECT imaging in small laboratory animals. J Nucl Med 1994;35:342-48
49. Gilland DR, Johnson EL, Turkington TG, et al. Evaluation of a pinhole collimator for I-131 SPECT head imaging. IEEE Trans Nucl Sci 1996;43:2230-38
50. Tenney CR, Smith MF, Greer KL, et al. Uranium pinhole collimators for I-131 SPECT imaging. IEEE Trans Nucl Sci 1999;46:1165-71
51. Tenney CR, Tornai MP, Smith MF, et al. Uranium pinhole collimators for 511-keV photon SPECT imaging of small volumes. IEEE Trans Nucl Sci 2001;48:1483-89
52. Larsson SA, Bergstrand G, Bergstedt H, et al. A special cut-off-camera for high-resolution SPECT of the head. J Nucl Med 1984;25:1023-30
53. Lassen NA, Sveinsdottir E, Kanno I, et al. A fast moving single-photon emission tomograph for regional cerebral blood flow studies in man. J Comput Assist Tomogr 1978;2:661-62
54. Genna S, Smith AP. The development of ASPECT, an annular single crystal brain camera for high-efficiency SPECT. IEEE Trans Nucl Sci 1988;35:654-58
55. Ouyang J, El Fakhri G, Xia W, et al. The design and manufacture of an annular variable-focusing collimator for high-sensitivity brain SPECT. IEEE Trans Nucl Sci 2006;53:2613-18
56. Rogers WL, Clinthorne NH, Shao L, et al. SPRINT II: a second generation single photon ring tomography. IEEE Trans Med Imaging 1988;7:291-97
57. Chang W, Huang G, Tian Z, et al. Initial characterization of a prototype multicrystal cylindrical SPECT system. IEEE Trans Nucl Sci 1992;39:1084-87
58. Rowe RK, Aarsvold JN, Barrett HH, et al. A stationary hemispherical SPECT imager for three-dimensional brain imaging. J Nucl Med 1993;34:474-80
59. Esser PD, Mitnick RJ, Arliss J, et al. Angular single photon emission computed tomography (SPECT): an improved method for cranial tomographic imaging. J Nucl Med 1983;24:P75
60. Polak JF, Holman BL, Moretti J-L, et al. I-123 HIPDM brain imaging with a rotating gamma camera and slant-hole collimator. J Nucl Med 1984;25:495-98
61. Liu J, Chang W, Loncaric S. Comparison of different imaging geometries of brain SPECT systems. IEEE Trans Nucl Sci 1995;42:1147-53
62. Fulton RR, Eberl S, Meikle SR, et al. A practical 3D tomographic method for correcting patient head motion in clinical SPECT. IEEE Trans Nucl Sci 1999;46:667-72
63. Smith MF, Jaszczak RJ. A rotating parallel-hole collimator for high-resolution imaging of medium energy radionuclides. IEEE Trans Nucl Sci 1998;45:2102-12
64. Lim CB, Chang LT, Jaszczak RJ. Performance analysis of three camera configurations for single photon emission computed tomography. IEEE Trans on Nucl Sci 1980;27:559-68
65. Jaszczak RJ, Tsui BMW. Single photon emission computed tomography (SPECT). In: Wagner HN, ed. Principles of Nuclear Medicine. Philadelphia: Saunders; 1995
66. Orlov SS. Theory of three dimensional reconstruction. I. Conditions for a complete set of projections. Sov Phys Crystallogr 1975;20:312-14
67. . American Society of Nuclear Cardiology. Updated imaging guidelines for nuclear cardiology procedures. J Nucl Cardiol 2001;8(pt 1):G1-G58
68. Liu Y-H, Lam PT, Sinusas AJ, et al. Differential effect of 180° and 360° acquisition orbits on the accuracy of SPECT imaging: quantitative evaluation in phantoms. J Nucl Med 2002;43:1115-24
69. Shih WJ, Wierzbinski B, Liu Y-H. Cardiac SPECT: 360° circular acquisition may resolve defects of 180° data. J Nucl Med 2003;44:995-96
70. Tuy HK. An inversion formula for cone-beam reconstruction. SIAM J Appl Math 1983;43:546-52
71. Ter-Antonyan R, Jaszczak RJ, Bowsher JE, et al. Brain SPECT simulation using half-cone-beam collimation and single-revolution helical-path acquisition. IEEE Trans Nucl Sci 2007;54:475-79
72. Smith BD. Cone-beam tomography: recent advances and a tutorial review. Opt Eng 1990;29:524-34
73. Kamphuis C, Beekman FJ. A feasibility study of offset cone-beam collimators for combined emission transmission brain SPECT on a dual-head system. IEEE Trans Nucl Sci 1998;45:1250-54
74. Lalush DS, DiMeo AJ. An observer study evaluating dual-plane circular-orbit cone-beam brain SPECT. J Nucl Med 2002;43:1578-83
75. Stone CD, Smith MF, Greer KL, et al. A combined half-cone beam and parallel-hole collimation system for SPECT brain imaging. IEEE Trans Nucl Sci 1998;45:1219-24
76. Lang TF, Hasegawa BH, Liew SC, et al. Description of a prototype emission-transmission computed-tomography imaging system. J Nucl Med 1992;33:1881-87
77. Patton JA, Turkington TG. SPECT/CT physical principles and attenuation correction. J Nucl Med Tech 2008;36:1-10
78. Schillaci O. Hybrid SPECT/CT: a new era for SPECT imaging? Eur J Nucl Med Mol Imaging 2005;32:521-24
79. van Laere K, Koole M, Kauppinen T, et al. Nonuniform transmission in brain SPECT using 201Tl, 153Gd, and 99mTc static line sources: anthropomorphic dosimetry studies and influence on brain quantification. J Nucl Med 2000;41:2051-62
80. Bruyant PP. Analytic and iterative reconstruction algorithms in SPECT. J Nucl Med 2002;43:1343-58
81. van Laere K, Koole M, Lemahieu I, et al. Image filtering in single-photon emission computed tomography: principles and applications. Comput Med Imaging Graph 2001;25:127-33
82. Gilland DR, Tsui BMW, MacCartney WH, et al. Determination of the optimum filter function for SPECT imaging. J Nucl Med 1988;29:643-50
83. Perter TM, Lewitt RM. Computed tomography with fan bean geometry. J Comput Assist Tomogr 1977;1:429-36
84. Smith BD. Derivation of the extended fan-beam formula. IEEE Trans Med Imaging 1985;4:177-84
85. Feldkamp LA, Davis LC, Kress JW. Practical cone-beam algorithm. J Opt Soc Am A 1984;1:612-19
86. Pack JD, Noo F, Clackdoyle R. Cone-beam reconstruction using the back-projection of locally filtered projections. IEEE Trans Med Imaging 2005;24:70-85
87. Zhao S, Yu H, Wang G. A unified framework for exact cone-beam reconstruction formulas. Med Phys 2005;32:1712-21
88. Tang Q, Zeng GL, Gullberg GT. Analytical fan-beam and cone-beam reconstruction algorithms with uniform attenuation correction for SPECT. Phys Med Biol 2005;50:3153-70
89. Gordon R, Bender R, Herman GT. Algebraic reconstruction techniques (ART) for three-dimensional electron microscopy and x-ray photography. J Theoret Biol 1970;29:471-82
90. Andersen AH, Kak AC. Simultaneous algebraic reconstruction technique (SART): a superior implementation of the ART algorithm. Ultrason Imag 1984;6:81-94
91. Shepp LA, Vardi Y. Maximum likelihood reconstruction for emission tomography. IEEE Trans Med Imaging 1982;1:113-22
92. Hudson HM, Larkin RS. Accelerated image reconstruction using ordered subsets of projection data. IEEE Trans Med Imaging 1994;13:601-09
93. Browne JA, De Pierro AE. A row-action alternative to the EM algorithm for maximizing likelihoods in emission tomography. IEEE Trans Med Imaging 1996;15:687-99
94. Mumcuoglu E, Leahy R, Cherry S, et al. Fast gradient-based methods for Bayesian reconstruction of transmission and emission PET images. IEEE Trans Med Imaging 1994;13:687-701
95. Zaidi H, Hasegawa BH. Determination of the attenuation map in emission tomography. J Nucl Med 2003;44:291-315
96. Árlig Å, Gustafsson A, Jacobsson L, et al. Attenuation correction in quantitative SPECT of cerebral blood flow: a Monte Carlo study. Phys Med Biol 2000;45:3847-59
97. Licho R, Glick SJ, Xia W, et al. Attenuation compensation in 99mTc SPECT brain imaging: a comparison of the use of attenuation maps derived from transmission versus emission data in normal scans. J Nucl Med 1999;40:456-63
98. Tsui BM, Gullberg GT, Edgerton ER, et al. Correction of nonuniform attenuation in cardiac SPECT imaging. J Nucl Med 1989;30:497-507
99. Farncombe TH, Gifford HC, Narayanan MV, et al. Assessment of scatter compensation strategies for (67)Ga SPECT using numerical observers and human LROC studies. J Nucl Med 2004;45:802-12
100. Matsuda H, Ohnishi T, Asada T, et al. Correction for partial-volume effects on brain perfusion SPECT in healthy men. J Nucl Med 2003;44:1243-52
101. Du Y, Tsui BMW, Frey EC. Partial volume effect compensation for quantitative brain SPECT imaging. IEEE Trans Med Imaging 2005;24:969-76
102. Gullberg GT, Tsui BMW, Crawford CR, et al. Estimation of geometrical parameters for fan beam tomography. Phys Med Biol 1987;32:1581-94
103. Zaidi H, Koral KF. Scatter modelling and compensation in emission tomography. Eur J Nucl Med Mol Imaging 2004;31:761-82. Epub 2004 Mar 31
104. Seo Y, Wong KH, Sun M, et al. Correction of photon attenuation and collimator response for a body-contouring SPECT/CT imaging system. J Nucl Med 2005;46:868-77
105. King MA, Glick SJ, Pretorius PH, et al. Attenuation, scatter and spatial resolution compensation in SPECT. In: Wernick MN, Aarsvold JN, eds. Emission Tomography: The Fundamentals of SPECT and PET. San Diego: Elsevier; 2004:473-98
106. El Fakhri G, Kijewski MF, Albert MS, et al. Quantitative SPECT leads to improved performance in discrimination tasks related to prodromal Alzheimer's disease. J Nucl Med 2004;45:2026-31
107. Du Y, Tsui BMW, Frey EC. Model-based compensation for quantitative 123I brain SPECT imaging. Phys Med Biol 2006;51:1269-82
108. Celler A, Dixon KL, Chang Z, et al. Problems created in attenuation-corrected SPECT images by artifacts in attenuation maps: a simulation study. J Nucl Med 2005;46:335-43
109. El Fakhri, G Buvat I, Benali H, et al. Relative impact of scatter, collimator response, attenuation, and finite spatial resolution corrections in cardiac SPECT. J Nucl Med 2000;41:1400-08
110. Harel F, Genin R, Daou D, et al. Clinical impact of combination of scatter, attenuation correction, and depth-dependent resolution recovery for 201Tl studies. J Nucl Med 2001;42:1451-56
111. Bin H, Frey EC. Comparison of conventional, model-based quantitative planar, and quantitative SPECT image processing methods for organ activity estimation using In-111 agents. Phys Med Biol 2006;51:3967-81
112. El Fakhri G, Moore SC, Maksud P, et al. Absolute activity quantitation in simultaneous 123I/99mTc brain SPECT. J Nucl Med 2001;42:300-08
113. Devous MD, Lowe JL, Payne JK. Dual-isotope brain SPECT imaging with technetium and iodine-123: validation by phantom studies. J Nucl Med 1992;33:2030-35
114. Ivanovic M, Weber DA, Loncaric S, et al. Feasibility of dual radionuclide imaging with I-123 and Tc-99m. Med Phys 1994;21:667-74
115. Hashimoto J, Sasaki T, Itoh Y, et al. Brain SPECT imaging using three different tracers in subacute cerebral infarction. Clin Nucl Med 1998;23:275-77
116. Schramm NU, Ebel G, Engeland U, et al. High-resolution SPECT using multipinhole collimation. IEEE Trans Nucl Sci 2003;50:315-20
117. Vastenhouw B, Beekman FJ. Submillimeter total-body murine imaging with U-SPECT-I. J Nucl Med 2007;48:487-93
118. McElroy DP, MacDonald LR, Beekman FJ, et al. Performance evaluation of A-SPECT: a high-resolution desktop pinhole SPECT system for imaging small animals. IEEE Trans Nucl Sci 2002;49:2139-47
119. Acton PD, Kung M-P, Hou C., et al. Ultra-high resolution single photon emission tomography imaging of the mouse striatum. Eur J Nucl Med 2002;29:446
120. Kastis GA, Barber HB, Barrett HH, et al. Gamma-ray imaging using a CdZnTe pixel array and a high-resolution, parallel-hole collimator. IEEE Trans Nucl Sci 2000;47:1923-27
121. Barrett HH, Swindell W. Radiological Imaging. New York: Academic Press; 1981