-
1
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
Imai S, Armstrong CM, Kaeberlein M, Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 2000 403 : 795 800.
-
(2000)
Nature
, vol.403
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
2
-
-
34249083199
-
Sirtuins in mammals: Insights into their biological function
-
Michan S, Sinclair D. Sirtuins in mammals: insights into their biological function. Biochem J 2007 404 : 1 13.
-
(2007)
Biochem J
, vol.404
, pp. 1-13
-
-
Michan, S.1
Sinclair, D.2
-
3
-
-
38949212965
-
Aging and anti-aging: Unexpected side effects of everyday medication through sirtuin1 modulation
-
Engel N, Mahlknecht U. Aging and anti-aging: unexpected side effects of everyday medication through sirtuin1 modulation. Int J Mol Med 2008 21 : 223 32.
-
(2008)
Int J Mol Med
, vol.21
, pp. 223-32
-
-
Engel, N.1
Mahlknecht, U.2
-
4
-
-
34547914840
-
Sirtuins: The 'magnificent seven', function, metabolism and longevity
-
Dali-Youcef N, Lagouge M, Froelich S, Koehl C, Schoonjans K, Auwerx J. Sirtuins: the 'magnificent seven', function, metabolism and longevity. Ann Med 2007 39 : 335 45.
-
(2007)
Ann Med
, vol.39
, pp. 335-45
-
-
Dali-Youcef, N.1
Lagouge, M.2
Froelich, S.3
Koehl, C.4
Schoonjans, K.5
Auwerx, J.6
-
5
-
-
33751113602
-
Mammalian sirtuins - Emerging roles in physiology, aging, and calorie restriction
-
Haigis MC, Guarente LP. Mammalian sirtuins - emerging roles in physiology, aging, and calorie restriction. Genes Dev 2006 20 : 2913 21.
-
(2006)
Genes Dev
, vol.20
, pp. 2913-21
-
-
Haigis, M.C.1
Guarente, L.P.2
-
6
-
-
3042681042
-
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
-
Picard F, Kurtev M, Chung N, Topark-Ngarm A, Senawong T, Machado De Oliveira R et al. Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ. Nature 2004 429 : 771 6.
-
(2004)
Nature
, vol.429
, pp. 771-6
-
-
Picard, F.1
Kurtev, M.2
Chung, N.3
Topark-Ngarm, A.4
Senawong, T.5
MacHado De Oliveira, R.6
-
7
-
-
0037291214
-
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
-
North BJ, Marshall BL, Borra MT, Denu JM, Verdin E. The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. Mol Cell 2003 11 : 437 44.
-
(2003)
Mol Cell
, vol.11
, pp. 437-44
-
-
North, B.J.1
Marshall, B.L.2
Borra, M.T.3
Denu, J.M.4
Verdin, E.5
-
8
-
-
0041829415
-
Proteomics-based identification of differentially expressed genes in human gliomas: Down-regulation of SIRT2 gene
-
Hiratsuka M, Inoue T, Toda T, Kimura N, Shirayoshi Y, Kamitani H et al. Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene. Biochem Biophys Res Commun 2003 309 : 558 66.
-
(2003)
Biochem Biophys Res Commun
, vol.309
, pp. 558-66
-
-
Hiratsuka, M.1
Inoue, T.2
Toda, T.3
Kimura, N.4
Shirayoshi, Y.5
Kamitani, H.6
-
9
-
-
34547397081
-
SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation
-
Jing E, Gesta S, Kahn CR. SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation. Cell Metab 2007 6 : 105 14.
-
(2007)
Cell Metab
, vol.6
, pp. 105-14
-
-
Jing, E.1
Gesta, S.2
Kahn, C.R.3
-
10
-
-
34447626095
-
SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction
-
Wang F, Nguyen M, Qin FX, Tong Q. SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction. Aging Cell 2007 6 : 505 14.
-
(2007)
Aging Cell
, vol.6
, pp. 505-14
-
-
Wang, F.1
Nguyen, M.2
Qin, F.X.3
Tong, Q.4
-
11
-
-
22744444561
-
Calorie restriction and SIR2 genes - Towards a mechanism
-
Guarente L. Calorie restriction and SIR2 genes - towards a mechanism. Mech Ageing Dev 2005 126 : 923 8.
-
(2005)
Mech Ageing Dev
, vol.126
, pp. 923-8
-
-
Guarente, L.1
-
12
-
-
0034626735
-
Oxidants, oxidative stress and the biology of ageing
-
Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 2000 408 : 239 47.
-
(2000)
Nature
, vol.408
, pp. 239-47
-
-
Finkel, T.1
Holbrook, N.J.2
-
13
-
-
4243077568
-
Basal and postprandial substrate oxidation rates in obese women receiving two test meals with different protein content
-
Labayen I, Díez N, Parra D, González A, Martínez JA. Basal and postprandial substrate oxidation rates in obese women receiving two test meals with different protein content. Clin Nutr 2004 23 : 571 8.
-
(2004)
Clin Nutr
, vol.23
, pp. 571-8
-
-
Labayen, I.1
Díez, N.2
Parra, D.3
González, A.4
Martínez, J.A.5
-
14
-
-
0034569866
-
Obesity: Preventing and managing the global epidemic. Report of a WHO consultation
-
World Health Organization.
-
World Health Organization. Obesity: preventing and managing the global epidemic. Report of a WHO consultation. Word Health Organ Tech Resp Ser 2000 894 : 1 253.
-
(2000)
Word Health Organ Tech Resp Ser
, vol.894
, pp. 1-253
-
-
-
15
-
-
33947538478
-
A hypocaloric diet enriched in legumes specifically mitigates lipid peroxidation in obese subjects
-
Crujeiras AB, Parra D, Abete I, Martinez JA. A hypocaloric diet enriched in legumes specifically mitigates lipid peroxidation in obese subjects. Free Radic Res 2007 41 : 498 506.
-
(2007)
Free Radic Res
, vol.41
, pp. 498-506
-
-
Crujeiras, A.B.1
Parra, D.2
Abete, I.3
Martinez, J.A.4
-
16
-
-
33646413180
-
A role for fruit content in energy-restricted diets in improving antioxidant status in obese women during weight loss
-
Crujeiras AB, Parra MD, Rodriguez MC, Martinez de Morentin BE, Martinez JA. A role for fruit content in energy-restricted diets in improving antioxidant status in obese women during weight loss. Nutrition 2006 22 : 593 9.
-
(2006)
Nutrition
, vol.22
, pp. 593-9
-
-
Crujeiras, A.B.1
Parra, M.D.2
Rodriguez, M.C.3
Martinez De Morentin, B.E.4
Martinez, J.A.5
-
17
-
-
33846114275
-
Appetite sensations and satiety quotient: Predictors of energy intake and weight loss
-
Drapeau V, King N, Hetherington M, Doucet E, Blundell J, Tremblay A. Appetite sensations and satiety quotient: predictors of energy intake and weight loss. Appetite 2007 48 : 159 66.
-
(2007)
Appetite
, vol.48
, pp. 159-66
-
-
Drapeau, V.1
King, N.2
Hetherington, M.3
Doucet, E.4
Blundell, J.5
Tremblay, A.6
-
19
-
-
15544383692
-
Postprandial insulin response and mitochondrial oxidation in obese men nutritionally treated to lose weight
-
Parra MD, Martínez de Morentín BE, Martínez JA. Postprandial insulin response and mitochondrial oxidation in obese men nutritionally treated to lose weight. Eur J Clin Nutr 2005 59 : 334 40.
-
(2005)
Eur J Clin Nutr
, vol.59
, pp. 334-40
-
-
Parra, M.D.1
Martínez De Morentín, B.E.2
Martínez, J.A.3
-
20
-
-
21644441612
-
[in vivo study of mitochondrial oxidation in obese patients treated by means of calorie restriction]
-
(in Spanish).
-
Parra MD, Martínez de Morentín BE, Pérez S, Rodríguez MC, Martínez JA. [In vivo study of mitochondrial oxidation in obese patients treated by means of calorie restriction]. Nutr Hosp 2004 19 : 269 76 (in Spanish).
-
(2004)
Nutr Hosp
, vol.19
, pp. 269-76
-
-
Parra, M.D.1
Martínez De Morentín, B.E.2
Pérez, S.3
Rodríguez, M.C.4
Martínez, J.A.5
-
21
-
-
33746397949
-
Nutritional aspects of breath testing based on stable isotopes
-
Parra MD, Martínez JA. Nutritional aspects of breath testing based on stable isotopes. Nutr Rev 2006 64 : 338 47.
-
(2006)
Nutr Rev
, vol.64
, pp. 338-47
-
-
Parra, M.D.1
Martínez, J.A.2
-
22
-
-
0021813187
-
Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
-
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985 28 : 412 9.
-
(1985)
Diabetologia
, vol.28
, pp. 412-9
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
Naylor, B.A.4
Treacher, D.F.5
Turner, R.C.6
-
23
-
-
4644338458
-
Circulating mononuclear cells in the obese are in a proinflammatory state
-
Ghanim H, Aljada A, Hofmeyer D, Syed T, Mohanty P, Dandona P. Circulating mononuclear cells in the obese are in a proinflammatory state. Circulation 2004 110 : 1564 71.
-
(2004)
Circulation
, vol.110
, pp. 1564-71
-
-
Ghanim, H.1
Aljada, A.2
Hofmeyer, D.3
Syed, T.4
Mohanty, P.5
Dandona, P.6
-
25
-
-
33947190432
-
11-β Hydroxysteroid dehydrogenase type 2 expression in white adipose tissue is strongly correlated with adiposity
-
Milagro FI, Campion J, Martinez JA. 11-β Hydroxysteroid dehydrogenase type 2 expression in white adipose tissue is strongly correlated with adiposity. J Steroid Biochem Mol Biol 2007 104 : 81 4.
-
(2007)
J Steroid Biochem Mol Biol
, vol.104
, pp. 81-4
-
-
Milagro, F.I.1
Campion, J.2
Martinez, J.A.3
-
26
-
-
8544265309
-
Oxidative modification of mitochondrial respiratory complexes in response to the stress of Trypanosoma cruzi infection
-
Wen JJ, Garg N. Oxidative modification of mitochondrial respiratory complexes in response to the stress of Trypanosoma cruzi infection. Free Radic Biol Med 2004 37 : 2072 81.
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 2072-81
-
-
Wen, J.J.1
Garg, N.2
-
27
-
-
0037221950
-
Mutations in COX15 produce a defect in the mitochondrial heme biosynthetic pathway, causing early-onset fatal hypertrophic cardiomyopathy
-
Antonicka H, Mattman A, Carlson CG, Glerum DM, Hoffbuhr KC, Leary SC et al. Mutations in COX15 produce a defect in the mitochondrial heme biosynthetic pathway, causing early-onset fatal hypertrophic cardiomyopathy. Am J Hum Genet 2003 72 : 101 14.
-
(2003)
Am J Hum Genet
, vol.72
, pp. 101-14
-
-
Antonicka, H.1
Mattman, A.2
Carlson, C.G.3
Glerum, D.M.4
Hoffbuhr, K.C.5
Leary, S.C.6
-
28
-
-
0006020398
-
How to calculate sample size for an experiment: A case-based description
-
Mera R, Thompson H, Prasad C. How to calculate sample size for an experiment: a case-based description. Nutr Neurosci 1998 1 : 87 91.
-
(1998)
Nutr Neurosci
, vol.1
, pp. 87-91
-
-
Mera, R.1
Thompson, H.2
Prasad, C.3
-
29
-
-
37448999140
-
Impact of fish intake on oxidative stress when included into a moderate energy-restricted program to treat obesity
-
Parra D, Bandarra NM, Kiely M, Thorsdottir I, Martinez JA. Impact of fish intake on oxidative stress when included into a moderate energy-restricted program to treat obesity. Eur J Nutr 2007 46 : 460 7.
-
(2007)
Eur J Nutr
, vol.46
, pp. 460-7
-
-
Parra, D.1
Bandarra, N.M.2
Kiely, M.3
Thorsdottir, I.4
Martinez, J.A.5
-
30
-
-
33846867711
-
Dietary α-linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjects
-
Zhao G, Etherton TD, Martin KR, Gillies PJ, West SG, Kris-Etherton PM. Dietary α-linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjects. Am J Clin Nutr 2007 85 : 385 91.
-
(2007)
Am J Clin Nutr
, vol.85
, pp. 385-91
-
-
Zhao, G.1
Etherton, T.D.2
Martin, K.R.3
Gillies, P.J.4
West, S.G.5
Kris-Etherton, P.M.6
-
31
-
-
14844317297
-
Molecular links between aging and adipose tissue
-
Picard F, Guarente L. Molecular links between aging and adipose tissue. Int J Obes (Lond) 2005 29 : 36 9.
-
(2005)
Int J Obes (Lond)
, vol.29
, pp. 36-9
-
-
Picard, F.1
Guarente, L.2
-
32
-
-
33746825135
-
Different dietary strategies for weight loss in obesity: Role of energy and macronutrient content
-
Abete I, Parra MD, Zulet MA, Martnez JA. Different dietary strategies for weight loss in obesity: Role of energy and macronutrient content. Nutr Res Rev 2006 19 : 1 19.
-
(2006)
Nutr Res Rev
, vol.19
, pp. 1-19
-
-
Abete, I.1
Parra, M.D.2
Zulet, M.A.3
Martnez, J.A.4
-
33
-
-
33846583673
-
SIR2: A potential target for calorie restriction mimetics
-
Chen D, Guarente L. SIR2: a potential target for calorie restriction mimetics. Trends Mol Med 2007 13 : 64 71.
-
(2007)
Trends Mol Med
, vol.13
, pp. 64-71
-
-
Chen, D.1
Guarente, L.2
-
34
-
-
24944559665
-
HST2 mediates SIR2-independent life-span extension by calorie restriction
-
Lamming DW, Latorre-Esteves M, Medvedik O, Wong SN, Tsang FA, Wang C et al. HST2 mediates SIR2-independent life-span extension by calorie restriction. Science 2005 309 : 1861 4.
-
(2005)
Science
, vol.309
, pp. 1861-4
-
-
Lamming, D.W.1
Latorre-Esteves, M.2
Medvedik, O.3
Wong, S.N.4
Tsang, F.A.5
Wang, C.6
-
35
-
-
30444439216
-
The discovery of nitric oxide and its role in vascular biology
-
Moncada S, Higgs EA. The discovery of nitric oxide and its role in vascular biology. Br J Pharmacol 2006 147 : 193 201.
-
(2006)
Br J Pharmacol
, vol.147
, pp. 193-201
-
-
Moncada, S.1
Higgs, E.A.2
-
36
-
-
33947710793
-
Calorie restriction increases muscle mitochondrial biogenesis in healthy humans
-
Civitarese AE, Carling S, Heilbronn LK, Hulver MH, Ukropcova B, Deutsch WA et al. Calorie restriction increases muscle mitochondrial biogenesis in healthy humans. PLoS Med 2007 4 : e76.
-
(2007)
PLoS Med
, vol.4
-
-
Civitarese, A.E.1
Carling, S.2
Heilbronn, L.K.3
Hulver, M.H.4
Ukropcova, B.5
Deutsch, W.A.6
-
38
-
-
33947327738
-
ESCI Award 2006. Mitochondrial function and endocrine diseases
-
Stark R, Roden M. ESCI Award 2006. Mitochondrial function and endocrine diseases. Eur J Clin Invest 2007 37 : 236 48.
-
(2007)
Eur J Clin Invest
, vol.37
, pp. 236-48
-
-
Stark, R.1
Roden, M.2
|